Subinguinal versus peritesticular diameters of varicocele veins in the supine and standing posture

Author(s):  
Muhammad Asharib Arshad ◽  
Amjad Ali Siddiqui ◽  
Khaleeq ur Rehman

Objective: Scrotal CDUS is a standard investigation for varicocele patients, but it is not clear that which region should be considered as a standard. The aim of study was to determine that which region should be taken as a standard of measurement for varicocele veins. Methods: The study was conducted at the andro-urology clinic of a teaching hospital. Scrotal Color Doppler Ultrasound (CDUS) parameters were determined at subinguinal and peritesticular region in 35 varicocele patients. The data was collected as mean ± SD and compared using paired t test. Results: In supine position, the mean diameters of varicocele vein at peritesticular region (3.31mm ± 0.70) was compared with the mean diameters of varicocele vein at subinguinal region (2.94mm ± 0.52) and were found to be significantly greater (p < 0.01). The mean diameters of varicocele vein at peritesticular region, when measured in standing posture (3.65mm ± 0.77) was significantly greater (p < 0.01) than the mean diameters at subinguinal region (3.29mm ± 0.62). All varicocele patients had associated semen abnormalities but the diameter of varicocele veins had no significant correlation with semen abnormalities. Conclusion: The varicocele vein diameter at peritesticular region was found to be significantly greater than the sub-inguinal varicocele vein diameter in both lying and standing position. The diameters at peritesticular region may be routinely measured to reach at a better clinical decision. Continuous...

2012 ◽  
Vol 2 ◽  
pp. 85 ◽  
Author(s):  
Nazanin Farshchian ◽  
Negin Rezavand ◽  
Saeed Mohammadi

Objective: To assess the effect of injecting magnesium sulfate on Doppler parameters of fetal umbilical and middle cerebral arteries (MCA) in women with severe preeclampsia. Materials and Methods: A total of 21 patients with severe preeclampsia admitted to Imam Reza Hospital, Kermanshah (Iran), were evaluated. Before and after administration of magnesium sulfate, Doppler ultrasound scan was carried out to measure fetal middle cerebral artery and umbilical artery blood flow. Paired t-test was used for statistical analysis. Results: After injection of magnesium sulfate, the mean resistivity index (RI)-umbilical, and pulsatility index (PI)-cerebral showed a statistically significant reduction (P < 0.001). The cerebroumbilical C/U ratio increased after the intervention (P < 0.001). The PI-umbilical (P = 0.1) and pre- and post-RI-cerebral (P = 0.96) did not have statistically significant changes. Conclusions: Infusion of magnesium sulfate significantly decreases the flow in the fetus RI-umbilical and PI-MCA, and it increases C/U ratio indices in color Doppler ultrasound.


Author(s):  
Merve Ergin ◽  
Serpil Erdogan ◽  
Onur Akturk ◽  
Ozcan Erel

AbstractBackground:This research investigated the effects of the transport of blood samples between centers/laboratories by car on coagulation tests.Methods:Five tubes of blood samples were taken from 20 healthy volunteers. The samples consisted of a baseline (control) group, centrifuged and noncentrifuged transported samples; centrifuged and noncentrifuged untransported samples. The groups of centrifuged and noncentrifuged samples were transported by car for 2 h. The centrifuged and noncentrifuged untransported samples were incubated in the laboratory until the transported samples arrived. Prothrombin time (PT) and activated partial thromboplastin time (APTT) tests were conducted for all samples.Results:Significant differences between the baseline group and the centrifuged and noncentrifuged transported samples and the noncentrifuged untransported samples were found for APTT levels (p<0.05, for all). In addition, significant mean percentage differences in PT values were found between the baseline group and the noncentrifuged transported samples (p<0.001) and the noncentrifuged untransported samples (p=0.005). The mean level of PT in the noncentrifuged transported samples was outside the upper limit of the clinical decision level.Conclusions:Noncentrifuged transported samples showed clinically significant differences in PT test results that may have stemmed from mechanical agitation during transportation. Therefore, we recommend not transporting noncentrifuged specimens for PT testing by car.


2020 ◽  
Vol 14 (4) ◽  
pp. 211-218
Author(s):  
Minh Tam Le ◽  
Dac Nguyen Nguyen ◽  
Thi Thanh Tam Nguyen ◽  
Vu Quoc Huy Nguyen ◽  
Chi Kong Pham ◽  
...  

<b><i>Objective: </i></b>Scrotal ultrasound is not a routine investigation in the clinical approach to male infertility analysis. This study aims to identify the role of testicular Doppler ultrasound in male infertility assessment and its relation to semen parameters in non-azoospermic men. <b><i>Methods: </i></b>Cross-sectional descriptive analysis of 558 men from infertile couples were examined at the Hue Center for Reproductive Endocrinology and Infertility, Hue University Hospital from June 2016 to May 2018. Some cohort characteristics, semen analysis and testicular Doppler ultrasound were analyzed. Men with acute systemic diseases, acute urinary tract infection, hepatic dysfunction, malignant diseases, retrograde ejaculation, cryptorchidism or azoospermia were excluded. <b><i>Results: </i></b>The mean volumes of the right and left testicles were 8.87 and 8.77 ml, respectively. The total volume of the 2 sides was 17.63 ± 4.34 ml (95% confidence interval 17.27-18.00 ml). The mean right resistive index (RI) was 0.61 ± 0.23, and the mean left RI was 0.59 ± 0.01. The rate of normal semen quality was 23.2% in group with varicocele and 30.6% in group with non-varicocele. The ultrasound results from the normal semen group were much different from those of the abnormal semen group regarding testicular volume: mean right testis volume: 9.67 ± 1.88 vs. 8.75 ± 2.34 ml, p = 0.0096; mean left testis volume: 9.54 ± 1.78 vs. 8.51 ± 2.44 ml, p = 0.0047; mean total volume of 2 sides: 19.21 ± 3.60 vs. 17.26 ± 4.59 ml, p = 0.005 (varicocele group); mean right testis volume: 9.21 ± 2.21 vs. 8.63 ± 2.21 ml, p = 0.029 (non-varicocele group). The other indexes of color Doppler ultrasound (peak systolic velocity, end diastolic velocity, RI) were not found to correlate with semen quality. <b><i>Conclusions: </i></b>Testicular volume which has a close relation to the semen parameters could be used as a clinical prediction factor for the quality of semen.


Neurosurgery ◽  
2004 ◽  
Vol 55 (1) ◽  
pp. 155-161 ◽  
Author(s):  
Robert J. Dempsey ◽  
Roham Moftakhar ◽  
Myron Pozniak

Abstract OBJECTIVE: Intraoperative color Doppler ultrasound has been used to locate arteriovenous malformations (AVMs). We describe the use of spectral Doppler to measure flow resistance and resistive index (RI) of vessels around the nidus to distinguish feeding arteries from en passant and normal vessels. This is particularly helpful in small AVMs and aids in the identification of normal vessels and completeness of resection by ruling out persistent low RI flow. METHODS: Seven patients with AVMs underwent resection. Spectral Doppler applied to the vessels in proximity to the AVM, along with calculated RI, was used to identify feeding arteries and draining veins. After presumed surgical resection of the AVM, pre-resection and postresection RIs were compared to identify residual AVM. Postoperative angiography was performed in all seven patients to confirm complete resection of the AVM. RESULTS: The mean pre-resection RI of vessels feeding the AVM was 0.34 (±0.01). In five patients without residual nidus on the basis of postresection color Doppler and postoperative angiogram, the postresection RI was 0.62 (±0.04). In two patients, the postresection scan identified a nidus with persistent low RI flow. Once residual AVM was resected, the RI became significantly higher. A postoperative angiogram confirmed complete resection of the AVM in all patients. CONCLUSION: Intraoperative duplex Doppler allowed more accurate localization of the AVM nidus. RI of the vessels around the AVM helped to distinguish vessels feeding the AVM from en passant vessels. Furthermore, comparison of pre-resection and postresection RI accurately indicated the completeness of resection.


2020 ◽  
Author(s):  
Wanli Liu ◽  
Lianxiang He ◽  
Wenjing Zeng ◽  
Liqing Yue ◽  
Jie Wei ◽  
...  

Abstract Background: With the extensive use of peripherally inserted central catheter (PICC), PICC-associated venous thrombosis (VT) has become one of the most important complications in the hospital. To reduce unnecessary Color Doppler Ultrasound (CDU) or imaging tests, D-dimer values are usually used to exclude VT for patients with low VT risk. There is little evidence for the usefulness of the D-dimer level as an independent diagnostic marker for excluding PICC-associated VT.Aims: To examine the effectiveness of D-dimer values to be used as an independent diagnostic marker for excluding PICC-associated Upper Extremity Venous Thrombosis(UEVT).Methods:Records were reviewed for 281 patients who underwent PICC insertion over the two years period in Xiangya Hospital Central South University.The patients were categorized into the UEVT unlikely group (<2 points) and the UEVT likely group (≥2 points) according to the Constans Clinical Decision Score( Constans score) post PICC insertion, before extubation. After the score was determined, the patients underwent a D-dimer test and CDU within 7 days after D-dimer test.Results: Among 281 patients, 180 patients (36%, 95%CI:30.6%-41.8%) had negative D-dimer results, 39 of 180 patients had VT despite having a negative D-dimer result, resulting in a failure rate of 21.7% (95% CI: 16.3–28.3%).The NPV of PICC-associated VT in the cancer group (80.0%,95% CI: 73.2–85.4%) was higher than that of the non-cancer group (60.0%,95% CI: 35.7–80.2%). The NPV of PICC-associated DVT(Deep Venous Thrombosis) (84.9%,95% CI: 78.7–89.6%) was lower than that of the PICC-associated SVT(Superficial Venous Thrombosis) (91.0% ,95% CI: 85.4–94.6%).Conclusion: The D-dimer levels maybe should not be used as a diagnostic index to rule out PICC-associated VT to avoid missed diagnosis of PICC-related VT, which may cause adverse consequences.


2021 ◽  
Vol 9 ◽  
Author(s):  
George Koshy Parapatt ◽  
Teresa Oranges ◽  
Guglielmo Paolantonio ◽  
Lucilla Ravà ◽  
Simona Giancristoforo ◽  
...  

Infantile hemangioma (IH) is the most common benign vascular tumor in childhood. In more than 85% of all cases, IHs undergo spontaneous involution, but nearly 10–12% of IHs develop complications and require immediate therapy. Oral propranolol is currently the first-line treatment for IHs. Color Doppler ultrasound is the gold standard in the diagnosis of deep IH, and it is used to evaluate the morphological change and the modification of vascularization that occur during its evolution and treatment. To date, only few data in the literature described the changes of intralesional arterial resistive index (RI) during treatment with propranolol; particularly, some authors have shown an increase of intralesional arterial RI in IHs with clinical regression during treatment with propranolol. The objective of this paper is to evaluate the changes of RI of the intralesional arteries of the IHs during the treatment with oral propranolol. We retrospectively analyzed a total of 64 IHs in 60 patients treated with oral propranolol with a good clinical response. Gray-scale ultrasonography and color Doppler imaging were performed before and during the therapy. The intralesional RIs were measured before and during the treatment. For each lesion, we recorded the RI values, and then we calculated the mean RI value for any single lesion. We compared the mean RI value observed at the baseline with the mean RI value of the last detectable sampling at color Doppler. We also compared between them the mean RI values observed during intermediate ultrasound. The RI values were compared in 44 lesions, with at least two significant samplings of RI. In the 44 lesions compared, we did not find statistically significant variations in the mean RI values between the baseline control and the values recorded at the last post-treatment control. The time trend of mean RI values of the intermediate color Doppler analysis performed between the first pre-treatment control and the last measurable control did not show any statistically significant variation in the trend of mean RI values. Contrarily to what has been described by some authors, in our experience, we have not observed an increase of RI in IHs treated with oral propranolol.


1998 ◽  
Vol 274 (2) ◽  
pp. R335-R338 ◽  
Author(s):  
Angelo Cagnacci ◽  
Serenella Arangino ◽  
Marco Angiolucci ◽  
Elisabetta Maschio ◽  
Gian Benedetto Melis

The cardiovascular effects induced by the daytime administration of melatonin (1 mg) were compared with those of placebo in 17 young, healthy, early follicular-phase women. Compared with placebo, the administration of melatonin modified, within 90 min, the pulsatility index (PI), evaluated by color Doppler ultrasound, of the internal carotid artery, abdominal aorta, and axillary artery. The effect was linearly related to baseline PI, higher baseline PI being associated with greater PI declines. Melatonin administration significantly decreased mean PI of internal carotid artery ( P < 0.02), systolic and diastolic blood pressure ( P < 0.01), and norepinephrine levels evaluated after 5 min of standing position ( P < 0.02). Heart rate and supine catecholamine levels were not modified. These data indicate that in young, healthy women the administration of 1 mg of melatonin greatly influences artery blood flow, decreases blood pressure, and blunts noradrenergic activation. Clinical implications of present data are worthy to be fully explored.


2020 ◽  
Vol 27 (12) ◽  
pp. 2681-2685
Author(s):  
Farzana . ◽  
Hafiza Khatoon ◽  
Ambreen Naz ◽  
Nousheen Mushtaq ◽  
Safia . ◽  
...  

Objectives: To assess the diagnostic accuracy of color Doppler ultrasound in antenatal diagnosis of placenta accreta taking histopathology as gold standard. Study Design: Prospective study. Setting: Department of Obstetrics and Gynaecology, Gambat Institute of Medical Sciences Gambat, Khairpur Sindh. Period: 1st December 2018 to 30th June 2019. Material & Methods: Women aged 20-45 years with previous history of placenta accrete and uterine scar were selected for the study. Informed consent was taken from women with placenta Previa and previous scar to undergo Doppler ultrasound. Results: A total of 115 patients participated in this study during one year time period. The mean age of e participants was found to be 33.71±5.61 years. The mean gestational age was 35.24±2.7weeks. Out of total 115 cases, previous cesarean section was found in 48 (41.7%) cases and previous history of placenta accreta was found in 9 (7.8%) cases. Sensitivity of Color Doppler ultrasound in diagnosis of placenta accreta was 85.7% and specificity 96.6%. Conclusion: There has always been a debate about the use of different modalities in detection of placenta accreta and its surgical management. Our study shows high sensitivity and specificity of color Doppler ultrasound in detection of placenta accreta. Large scale studies must be carried out on government level comparing the results of color Doppler and MRI and their outcomes.  


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