scholarly journals Clinical analysis of cases of lichen ruber planus in the oral cavity

2021 ◽  
Vol 2 (6) ◽  
pp. 46-52
Author(s):  
Irina K. Lutskaya ◽  
◽  
Olga G. Zinovenko ◽  
Irina O. Beloivanenk ◽  
◽  
...  

The manifestation of skin diseases in the oral cavity can be detected by doctors of any profile during the interview and examination of the patient. Often, the diagnosis is carried out by a dentist. A thorough diagnostic search allows you to determine the main clinical manifestations and treatment tactics. The dentist independently prescribes local therapy. A complex general effect is recommended by a dermatologist. Severe cases require inpatient treatment. A correct diagnosis and adequate medical measures improve the general condition and the local clinical picture, as well as contribute to a stable remission of the disease.

2018 ◽  
pp. 34-36
Author(s):  
P.M. Skrypnikov ◽  
T.P. Skrypnikova ◽  
Yu.M. Vitko

The statistics indicates on the tendency of morbidity rate of sarcoidosis to increase. The pathology affects young and older people notably. Sarcoidosis becomes a common chronic disease, which is often difficult to diagnose. Insufficient experience in recognition of this disease leads to misdiagnosis and ineffective treatment. All mentioned above highlights the extreme relevance of this issue. Sarcoidosis is a multisystem inflammatory nature disease of unknown etiology. The hereditary predisposition is taken to be but the whole family cases are also known. An abnormal immune response is also considered among the theories of the development of the disease. The infectious factor is also regarded as the cause of the disease. The increasing activity of lymphocytes, which start to produce substances promoting the formation of the granulomas, which are considered to be the basis for the pathological process, can initiate the onset of the disease. The maximum morbidity rate of sarcoidosis is observed between the ages of 35 to 55 years. Two age periods of the peak in male population are 35-40 years and about 55 years. The rate of sarcoidosis morbidity among female population is 65%. Up to 700 new cases of sarcoidosis are registered in Ukraine annually. The clinical signs of sarcoidosis vary. This pathology is more often manifested by the bilateral lymphadenopathy of lung roots, eyes and skin lesions. The liver, spleen, lymph nodes, heart, nervous system, muscles, bones and other organs can also be affected. In dental practice sarcoidosis can be manifested on the prolabium, oral mucosa and salivary glands. Blood laboratory indices (the increased level of calcium) are changed in sarcoidosis. Chest X-ray, MRI and CT also demonstrate changes in the lungs. The test for detection of granulomas shows positive Kveim reaction (the formation of purple-red nodules due to administration of antigen). Biopsy and bronchoscopy facilitate detection of both direct and indirect signs of sarcoidosis of the lungs. A general treatment of sarcoidosis is provided by a pulmonologist, who can assess the severity of the lesion and provide appropriate treatment. The core of treatment is based on corticosteroids. In severe cases immunosuppressors, anti-inflammatory drugs, antioxidants are prescribed. A dentist performs oral cavity sanation, professional hygiene. Mouth rinses with Dekasan solution, sublingual Lisobakt pills are prescribed to prevent inflammatory lesions. Patients with sarcoidosis are recommended to avoid solar radiation and contact with chemical and toxic substances harmful to the liver, reduction of the consumption of foods rich in calcium. Healthy life-style is crucial in prevention of exacerbations of sarcoidosis. In the remission period regular medical check-ups and oral cavity sanation are recommended. The correct diagnosis in rare diseases requires highly qualified dental professionals, the interdisciplinary approach in the diagnosing and management of patients with this pathology.


2020 ◽  
Vol 4 (10) ◽  
pp. 642-646
Author(s):  
I.I. Zakhur ◽  
◽  
S.V. Koshkin ◽  
V.A. Bobro ◽  
◽  
...  

The paper reviews current data on lichen ruber planus, a disease characterized by multifactorial pathogenesis, polymorphic clinical symptoms, severe long recurrent course, and a significant resistance to treatment. In the last decades, a substantial growth in the prevalence of this dermatosis is observed. Moreover, the rate of atypical cases also increases. The most common symptoms at disease onset are a generalized rash, severe itching, and malaise. Many patients present with acute clinical signs. Patients with the different forms of the disease (in particular, those with oral lichen planus) report on the significant reduction in the quality of life. The authors describe the specificity of clinical polymorphism, the variability of clinical manifestations and HLA system in annular lichen planus. The aim of this paper is to summarize currently available data considering the diversity of clinical variants which are required for the understanding of the pathogenesis to improve the diagnosis in difficult cases and to control its course. The authors also address a case study of annular lichen planus in a 63-year-old woman. KEYWORDS: lichen ruber planus, dermatosis, histopathology, HLA system. FOR CITATION: Zakhur I.I., Koshkin S.V., Bobro V.A. Annular lichen planus, a rare variant of lichen planus. Russian Medical Inquiry. 2020;4(10):642–646. DOI: 10.32364/2587-6821-2020-4-10-642-646.


2020 ◽  
Vol 74 (2) ◽  
pp. 127-129
Author(s):  
N.G. Klinova ◽  
◽  
I.N. Ivanova ◽  
V.V. Popov ◽  
V.I. Rusinov ◽  
...  

The article is devoted to reflexotherapy of patients with different dermatoses. The experience of treatment with acupuncture of chronic skin diseases in reflexotherapy room is analised. The selection of acupuncture meridians and points in dermatological patients is proposed. The results of acupuncture of patients with lichen ruber planus, atopic dermatitis, eczema, chronic urticaria, prurigo, psoriasis of palms and soles, lichen ruber pillaris Devergy are discussed. Effect of therapy on basis of psychosomatic nature is explained.


1930 ◽  
Vol 26 (7) ◽  
pp. 91-97
Author(s):  
I. A. Kugushev ◽  
M. B. Potashnik

The group of lichenoid skin diseases still occupies the attention of dermatologists. Different forms of papules belong to the group of lichen papules: Lichen ruber planus, acuminatus, verrucosus, obtusus, corneus pemphigoides, atrophicans and others. skin. This applies in particular to the subdivision of the forms Lichen ruber planus, Lichen acuminatus et verrucosus.


2020 ◽  
Vol 23 (3) ◽  
pp. 157-164
Author(s):  
Denis V. Zaslavsky ◽  
A. A. Sidikov ◽  
A. I. Sadykov ◽  
I. N. Chuprov ◽  
D. V. Kozlova ◽  
...  

Background: Lichen ruber planus (LP) and lichenoid skin reaction (LSR) are clinically and histologically similar. The performance of histological diagnosis in these diseases remains controversial. Materials and methods: We prospectively studied 33 patients with clinical manifestations and histological signs of the classic form of LP and LSR to assess the accuracy of an isolated histological LP and LSR examinations and to identify a variety of microscopic features. Each histological study was conducted by a pathomorphologist, who was blinded to the patients clinical characteristics and diagnosis. Results: Isolated histopathological examination made it possible to make a correct diagnosis in 25 (75%) of 33 patients: in particular, the diagnosis of LRC was established in 10 (30%), CPL-in 15 (45%) cases. Based on a combined assessment of histological and clinical data and response to therapy, the final diagnosis was established in 30 (91%) of the 33 patients who were divided into two groups. The first group comprised 18 patients diagnosed with LSR, and the second group comprised 12 patients diagnosed with the classic form of LP. Conclusions: Through this investigation, some differences in these diseases based on their clinical and pathomorphological features were identified. The diseases were characterized by different typical localizations and lesion sizes. The pathomorphology of both diseases is represented by lichenoid type of interface dermatitis.


2002 ◽  
Vol 55 (7-8) ◽  
pp. 325-328 ◽  
Author(s):  
Mirjana Poljacki ◽  
Mirjana Begenesic ◽  
Verica Djuran ◽  
Ljubinka Matovic ◽  
Milan Matic ◽  
...  

Introduction Presuming that psoriasis is an autoimmune skin disease, the aim of this study was to establish its association with other autoimmune skin diseases. The material was obtained at the Dermatovenereological Clinic Clinical Center Novi Sad. Material and methods This 10-year retrospective study (1990-1999) included 1743 psoriasis patients. The control group consisted of 7492 nonpsoriatic dermatological patients. Results Association of psoriasis with other dermatological diseases of autoimmune nature has been established in 13 (0.74 %) patients. The most frequent association was with lichen ruber planus in five patients, with alopecia areata and vitiligo in three patients, and in one with bullous pemphigoid and herpetiform dermatitis. Using Fisher's test no significant association was established. Discussion and conclusion According to literature data association of psoriasis with other autoimmune diseases is well known, but rare, which is in accordance with our results. The question arises whether this association is the matter of poor coexistence or the matter of genetic mutations. However, once established, these associations can further highlight the autoimmune nature of psoriasis. The research of autoimmunity would lead us to epithelial cells in thymus, and their badly learnt cognitive function about what is own, and what is not.


2017 ◽  
Vol 20 (1) ◽  
pp. 30-33
Author(s):  
Irina V. Khamaganova ◽  
E. N Malyarenko ◽  
E. V Denisova ◽  
I. V Vorontsova ◽  
K. T Plieva

The causes for the fault diagnosis of pemphigus vulgaris are discussed. The lowering of the age of patients noted the last years, clinical peculiarities similar with those in other bullous dermatoses and toxic epidermal necrolysis and multiforme exudative erythema are considered. A case in a 35-year old man who was sequentially in different clinics diagnosed Exacerbation of chronic nasopharyngitis. aphthous stomatitis, Lacunar tonsillitis. oral thrush, Chemical burn of the mucosa of the oral cavity, Chemical burn of the esophagus. Erosive - ulcerative form of lichen ruber planus of the mucosa of the oral cavity, Multiforme exudative erythema is presented. According to the diagnosis different medicines were prescribed, any improvement was not noted The vulgar pemphigus was diagnosed in 2 months after the appearance of the first eruption.


Author(s):  
Fedor Ermolyuk

Keratoconus is a dystrophic disease of the cornea, when it is thinned with the formation of a conus-like protrusion (protrusion of the cornea). This disease belongs to the group of keratectasia, it has a multifactorial nature and occurs in approximately 25 % of all corneal pathologies. The disease can be either primary, which is based on dystrophic changes in the cornea, or secondary, which develops against the background of prenatal keratitis. Keratoconus of iatrogenic origin, which develops as a result of refractive eye microsurgery, has become widespread during the last 20 years. Most often primary keratoconus manifests during puberty, progresses to 30–40 years, after which its development slows down. An early clinical manifestation of this corneal pathology is a progressive decrease in visual acuity, development of double vision (binocular diplopia) with the development of a strong headache against this background. Monocular polyopia — images and symbols with multiple contours — develops subsequently. Severe dry eyes, itching, photophobia appear in advanced stages. Diagnosis of keratoconus in some cases can be a significant difficulty, since the use of conventional research methods only allow to suspect refractive errors in the form of myopia or astigmatism. It is necessary to take into account the impossibility of correcting visual impairment using conventional methods — glasses or contact lenses — to make correct diagnosis. As a rule, diagnosis of keratoconus requires use of expanded spectrum of instrumental research methods.


Author(s):  
IV Petrov ◽  
TKh Amirova ◽  
LV Petrova ◽  
FS Petrova

Introduction: Healthcare-associated infections are of great socio-economic importance and are characterized by a large number of different pathogens. Nontuberculous mycobacteria are ubiquitous microorganisms that can circulate in a medical organization. The purpose of this review of epidemiologic studies was to establish the main features of mycobacteriosis as a healthcare-associated infection, taking into account the significance of the results and the compliance of the reviewed studies with the criteria of evidence-based medicine. Methods: We did a key word search for “nontuberculous mycobacteria”, “healthcare-associated infections”, and “mycobacteriosis” in several electronic bibliographic databases including Web of Science, PubMed, eLIBRARY, and ResearchGate and selected 127 out of 342 search results. Having analyzed the selected articles, we decided to include 34 of them in this study according to the topic of work. We established that nontuberculous mycobacteria can be found in various objects of health facilities, e.g. water supply systems, medical products and equipment. We also found that mycobacterial infection of nosocomial etiology could have various clinical manifestations (arthritis, keratitis, circulatory and skin diseases, etc.) determined by various aspects, such as heterogeneity of the group of nontuberculous mycobacteria, portals of entry (surgical procedures on various organs and systems of the human body, etc.), pathways of exposure and transmission factors. Resistance of nontuberculous mycobacteria to a number of disinfectants is a special question defining the importance of profound research in terms of ensuring sanitary and anti-epidemic (disinfection) safety within health facilities. Conclusions: Our findings indicate that mycobacterial infection can be considered as a healthcare-associated infection requiring an in-depth assessment from various perspectives including a microbiological monitoring of medical objects, statistical accounting of nosocomial infections, and clinical alertness in the diagnosis of mycobacteriosis by attending physicians and bacteriologists, etc.


Sign in / Sign up

Export Citation Format

Share Document