FEATURES OF THE PRODUCTION TECHNOLOGY LOW-PROTEIN FOODS

2021 ◽  
Vol 14 (3(53)) ◽  
pp. 98-104
Author(s):  
Alexey Iosifovich Grigel
Keyword(s):  
Amino Acids ◽  
Central Nervous System ◽  
Nervous System ◽  
Life Support ◽  
Hereditary Disease ◽  
Bakery Products ◽  
Severe Damage ◽  
Low Protein ◽  
The Central Nervous System ◽  
Manufacturing Technologies

Phenylketonuria is a hereditary disease associated with a violation of the metabolism of amino acids, in particular phenylalanine. It is accompanied by the accumulation of phenylalanine and its toxic products in the tissues, which leads to severe damage to the central nervous system, manifested, in particular, in a violation of mental development. An important component of the life support of such patients is the observance of a low-protein diet. The article describes the features of manufacturing technologies for lowprotein products, including such as low-protein pasta and cereals, low-protein dry mixes, small-piece bakery products. The technological process and equipment for the production of low-protein products are described, as well as the characteristics of the intake range of products are given.

scholarly journals Inhibition of choline acetyltransferase by excitatory amino acids as a possible mechanism for cholinergic dysfunction in the central nervous system

2001 ◽  
Vol 77 (4) ◽  
pp. 1136-1144 ◽  
Author(s):  
Nelson E. Loureiro-dos-Santos ◽  
Ricardo A. M. Reis ◽  
Regina C. C. Kubrusly ◽  
Olga M. M. S. De Almeida ◽  
Patricia F. Gardino ◽  
...  
Keyword(s):  
Amino Acids ◽  
Central Nervous System ◽  
Nervous System ◽  
Choline Acetyltransferase ◽  
Excitatory Amino Acids ◽  
Cholinergic Dysfunction ◽  
The Central Nervous System

scholarly journals Amino acid sequence of the encephalitogenic basic protein from human myelin

1971 ◽  
Vol 123 (1) ◽  
pp. 57-67 ◽  
Author(s):  
P. R. Carnegie
Keyword(s):  
Amino Acids ◽  
Central Nervous System ◽  
Nervous System ◽  
Amino Acid ◽  
Basic Protein ◽  
Structure And Function ◽  
Autoimmune Encephalomyelitis ◽  
The Central Nervous System ◽  
And Function ◽  
Experimental Autoimmune

Myelin from the central nervous system contains an unusual basic protein, which can induce experimental autoimmune encephalomyelitis. The basic protein from human brain was digested with trypsin and other enzymes and the sequence of the 170 amino acids was determined. The localization of the encephalitogenic determinants was described. Possible roles for the protein in the structure and function of myelin are discussed.

scholarly journals Exploring neurodegeneration at the atomic level

2018 ◽  
Vol 40 (5) ◽  
pp. 9-11
Author(s):  
Adam Tozer
Keyword(s):  
Amino Acids ◽  
Central Nervous System ◽  
Nervous System ◽  
Atomic Level ◽  
Tau Proteins ◽  
Microtubule Associated Proteins ◽  
Associated Proteins ◽  
The Central Nervous System ◽  
The Brain ◽  
Cell Maintenance

Tau proteins are microtubule-associated proteins essential for the correct functioning of neurons. This small family of proteins, 352–441 amino acids in length, are abundant in the brain and exist to stabilize microtubules in neurons and glia (non-neuronal cells of the central nervous system) to ensure correct trafficking of cellular cargo and cell maintenance.

scholarly journals Blood serum amino acids profile in patients with Multiple Sclerosis

2015 ◽  
Vol 26 (1) ◽  
pp. 50-53
Keyword(s):  
Multiple Sclerosis ◽  
Amino Acids ◽  
Central Nervous System ◽  
Nervous System ◽  
Blood Serum ◽  
Demyelinating Disease ◽  
Initial Step ◽  
Control Group ◽  
The Central Nervous System ◽  
Amino Acids Profile

Multiple sclerosis is the most common demyelinating disease of the central nervous system, affecting mostly young people. There were many risk factors for MS identified, however a direct cause of the disease is still unknown. Pathological changes in the SM lead to the myelin sheath damage around axons, what prevents proper transmission of nerve impulses in the central nervous system. The aim of this study was analyzing and comparing the amino acids profile in the blood serum of MS patients to control group of healthy individuals and evaluating the relationship between them. Significant (p<0.05) differences in the level of glutamate, aspartate and taurine in the blood serum of MS patients were revealed. A positive glutamate and aspartate level correlation in the serum has been demonstrated. Gender is significant only in the case of glutamate level in blood serum. The studies highlight the important role of neurotransmitters in MS and are the initial step in proteomic research.

DEVELOPMENT OF THE COMPONENT COMPOSITION OF AMINO ACID MIXTURES FOR THE NUTRITION OF PATIENTS WITH PHENYLKETONURIA

2021 ◽  
Vol 14 (1(51)) ◽  
pp. 31-42
Author(s):  
V. V. Shylau ◽  
H. A. Zhurnia
Keyword(s):  
Amino Acid ◽  
Component Composition ◽  
Hereditary Disease ◽  
Pku Phenylketonuria ◽  
Severe Damage ◽  
Special Diet ◽  
Low Protein ◽  
Amino Acid Mixtures ◽  
The Central Nervous System ◽  
The Republic

According to the Ministry of Health in the Republic of Belarus in 2019, there were about 500 patients with phenylketonuria (PKU). Phenylketonuria is a hereditary disease associated with a violation of the metabolism of amino acids, in particular phenylalanine (FA). This disease is accompanied by the accumulation of phenylalanine and its toxic products in the tissues, which leads to severe damage to the central nervous system, manifested in the form of impaired mental development. Many years of world experience shows that for the treatment of such patients, a special diet is prescribed using amino acid mixtures that do not contain phenylalanine or contain it in small amounts, as well as low-protein products based on starch, which are necessary to ensure an adequate energy value of the diet. The article presents the stages of development of the component composition of domestic amino acid mixtures for the nutrition of patients with phenylketonuria, taking into account their age characteristics.

scholarly journals Astroglial cradle in the life of the synapse

2014 ◽  
Vol 369 (1654) ◽  
pp. 20130595 ◽  
Author(s):  
Alexei Verkhratsky ◽  
Maiken Nedergaard
Keyword(s):  
Amino Acids ◽  
Central Nervous System ◽  
Nervous System ◽  
Synaptic Plasticity ◽  
Synaptic Connectivity ◽  
Synaptic Structure ◽  
Neuronal Membranes ◽  
The Central Nervous System ◽  
Multiple Molecules ◽  
Fundamental Mechanism

Astroglial perisynaptic sheath covers the majority of synapses in the central nervous system. This glial coverage evolved as a part of the synaptic structure in which elements directly responsible for neurotransmission (exocytotic machinery and appropriate receptors) concentrate in neuronal membranes, whereas multiple molecules imperative for homeostatic maintenance of the synapse (transporters for neurotransmitters, ions, amino acids, etc.) are shifted to glial membranes that have substantially larger surface area. The astrocytic perisynaptic processes act as an ‘astroglial cradle’ essential for synaptogenesis, maturation, isolation and maintenance of synapses, representing the fundamental mechanism contributing to synaptic connectivity, synaptic plasticity and information processing in the nervous system.

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