Morphometric Analysis and Characterization of Teeth Extracted from Mature Cystic Teratoma of the Ovary

ABSTRACT Mature cystic teratomas are a form of ovarian germ cell tumor and often called ‘dermoid cysts’ because they are mostly cystic. Many teratomas have teeth with morphologically identifiable crowns and roots. The objective of this study was to carry out morphometric measurements of teratomatous teeth extracted from a mature cystic teratoma excised from a 28-year-old female patient. The extracted teeth were stored in normal saline till they were subjected to morphometric analysis. All measurements were done using digital calipers (Derby, France), repeated twice and the average was recorded. The teeth were labeled as teratomatous tooth 1 (TT1), teratomatous tooth 2 (TT2) and teratomatous tooth 3 (TT3). The gross morphology of TT1 resembled a maxillary deciduous canine whereas TT2 and TT3 resembled a deciduous incisor and a mesioden respectively. The teratomatous broadly resembled normal intraoral teeth. With all of them primarily resembling maxillary deciduous teeth it would not be out of place to postulate that the displaced embryonic tissue leading to the formation of these was from the upper front region of the stomodeum. How to cite this article Togoo RA. Morphometric Analysis and Characterization of Teeth Extracted from Mature Cystic Teratoma of the Ovary. World J Dent 2013;4(3):155-157.

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Mature Cystic Teratoma of the Lung With a Somatic-Like Malignant Component in a Patient With Testicular Germ-Cell Tumor

Archivos de Bronconeumología (English Edition) ◽

10.1016/j.arbr.2018.03.009 ◽

2018 ◽

Vol 54 (12) ◽

pp. 629-630

Author(s):

Ana Vallejo-Benítez ◽

Enrique Rodríguez-Zarco ◽

Sofia Pereira-Gallardo ◽

Laura Macías-García

Keyword(s):

Germ Cell ◽

Germ Cell Tumor ◽

Cystic Teratoma ◽

Testicular Germ Cell Tumor ◽

Cell Tumor ◽

Mature Cystic Teratoma ◽

Testicular Germ Cell

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Mature Cystic Teratoma of the Lung With a Somatic-Like Malignant Component in a Patient With Testicular Germ-Cell Tumor

Archivos de Bronconeumología ◽

10.1016/j.arbres.2018.03.004 ◽

2018 ◽

Vol 54 (12) ◽

pp. 629-630

Author(s):

Ana Vallejo-Benítez ◽

Enrique Rodríguez-Zarco ◽

Sofia Pereira-Gallardo ◽

Laura Macías-García

Keyword(s):

Germ Cell ◽

Germ Cell Tumor ◽

Cystic Teratoma ◽

Testicular Germ Cell Tumor ◽

Cell Tumor ◽

Mature Cystic Teratoma ◽

Testicular Germ Cell

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Ovarian Germ Cell Tumor – Histopathological and statistical analysis

Journal of Pathology of Nepal ◽

10.3126/jpn.v3i6.8990 ◽

2013 ◽

Vol 3 (6) ◽

pp. 441-446

Author(s):

A Ghosh ◽

D Magar Gharti ◽

B Sathian ◽

R Narasimhan ◽

Op Talwar

Keyword(s):

Germ Cell ◽

Germ Cell Tumor ◽

Malignant Tumors ◽

Germ Cell Tumors ◽

Cystic Teratoma ◽

Cell Tumor ◽

Ovarian Tumors ◽

Mature Cystic Teratoma ◽

Age Group ◽

Malignant Germ Cell Tumors

Background: Ovarian cancers are common among females. The ovarian tumors are classified according to its histogenesis. In the present study, we analyzed the germ cell ovarian tumors reported in our institute. Materials and Methods: This study was a hospital based retrospective study. All ovarian germ cell tumor reported from Jan 2001 to Feb 2013 were retrieved and analyzed. The specimens were routinely processed and the slides were stained with H&E and special stains wherever required. Results: A total of 340 cases of ovarian tumors were reported and 150 cases (44%) were of germ cell origin. We had 137 cases of benign and 13 cases of malignant germ cell tumors. Most common subtype was mature cystic teratoma comprising 125 cases. Among the malignant cases, the most common was immature teratoma (5 cases). Age range in our series was from 8 to 82 years (mean 28 years). The most common age group affected was 21-30 years. Most of the malignant cases (76.9%) were in less than 30 years. Among the malignant cases majority (84.6%) were more than 10 cm in size. None of the malignant germ cell tumors were bilateral. Conclusion: Among germ cell tumors of ovary, mature cystic teratoma is the most common tumor and malignant subtypes are uncommon. Malignant tumors tend to occur in younger age group. DOI: http://dx.doi.org/10.3126/jpn.v3i6.8990 Journal of Pathology of Nepal (2013) Vol. 3, 441-446

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Bowel loop in an ovarian tumor: Grossly visible, completely developed intestinal loop in mature cystic teratoma of malignant mixed germ cell tumor

Pathology International ◽

10.1111/j.1440-1827.2009.02396.x ◽

2009 ◽

Vol 59 (7) ◽

pp. 479-481 ◽

Cited By ~ 5

Author(s):

Mi Jung Kwon ◽

Eun Sook Nam ◽

Seong Jin Cho ◽

Hyung Sik Shin ◽

Yeon Sik Na ◽

...

Keyword(s):

Germ Cell ◽

Germ Cell Tumor ◽

Ovarian Tumor ◽

Cystic Teratoma ◽

Cell Tumor ◽

Mature Cystic Teratoma ◽

Bowel Loop ◽

Intestinal Loop ◽

Mixed Germ Cell Tumor

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“Sack of marble” appearance in mature cystic teratoma: an unusual finding

Nepal Journal of Obstetrics and Gynaecology ◽

10.3126/njog.v16i1.37624 ◽

2021 ◽

Vol 16 (1) ◽

Author(s):

Prajmi Shrestha ◽

Gehanath Baral ◽

Rakina Bhansakarya ◽

Amar Nath Chaudhary

Keyword(s):

Germ Cell ◽

Germ Cell Tumor ◽

Cystic Teratoma ◽

Cell Tumor ◽

Mature Cystic Teratoma ◽

Menopausal Woman ◽

Rare Occasion ◽

Unusual Finding

Mature cystic teratoma (Dermoid) of ovary is a benign germ cell tumor consisting predominantly of ectodermal derivatives. In rare occasion sebaceous material may get aggregated to form marble like appearance because of continuous mobility of Dermoid and its content. Such a case in a menopausal woman has been presented in this report.

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Mature Cystic Teratoma of the Ovary; Clinicopathological Evaluation of 143 Cases in our Series, 5 Years Experience

Gynecology Obstetrics and Reproductive Medicine ◽

10.21613/gorm.2021.1189 ◽

2021 ◽

pp. 1-6

Author(s):

Betul Ogut ◽

Ferah Kazanci ◽

Dilek Yapar ◽

Özlem Erdem ◽

M.Anil Onan

Keyword(s):

Germ Cell ◽

Dermoid Cyst ◽

Malignant Transformation ◽

Germ Cell Tumor ◽

Cystic Teratoma ◽

Cell Tumor ◽

Mature Cystic Teratoma ◽

Tumor Diameter ◽

Preliminary Diagnosis ◽

Clinicopathological Findings

OBJECTIVE: Mature cystic teratoma, also known as a dermoid cyst, is the most common germ cell tumor of the ovary. In this retrospective study, it is aimed to evaluate clinicopathological findings of the patients who were operated on due to the preliminary diagnosis of dermoid cyst. STUDY DESIGN: Between May 2013 and May 2018, the findings of a total of 143 patients who were operated on with a preliminary diagnosis of dermoid cyst in our institution were analyzed retrospectively. In addition to demographic characteristics such as age, parity number and tumor size, lateralization, preoperative tumor markers, surgical procedure, presence of other pathological findings, and the rate of malignant transformation were analyzed. RESULTS: The median age of patients was 35.4 years and the ratio of nulliparous, primiparous, and multiparous patients was 46.9%, 25.2%, and 28%, respectively. The median tumor diameter was 6.7 cm, 50.3% of which were right-sided, 46.9% were left-sided and the remaining 2.8% were bilateral. Intraoperative torsion was found in 15 (10.5%) cases. The treatment consisted of 60.1% cystectomy by laparoscopy, 3.5% unilateral salpingo-oophorectomy by laparoscopy, 9.8% unilateral salpingo-oophorectomy by laparotomy, while the rate of 16.1% cases underwent hysterectomy with bilateral salpingo-oophorectomy by laparotomy, 10.5% of the cases, cysts were excised during cesarean section. As the final pathology report revealed, of 143 patients, immature teratoma was observed in five cases (3.5%), in one of them (0.7%) mixed germ cell tumor and in three of them (2.1%) borderline mucinous cancer, squamous cell carcinoma, and carcinoid tumor on mature cystic teratoma base were observed. CONCLUSION: Torsion is the most common complication with mature cystic teratoma. The size of the tumor is an important prognostic factor in terms of the malignant transformation of teratoma. Fertility sparing surgery with a minimally invasive surgical approach is available for fertility patients diagnosed with Mature cystic teratoma.

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Mediastinal Cystic Teratoma with Right Sided Extra Renal Wilms’ Tumor - A Rare Case Report

Bangladesh Journal of Child Health ◽

10.3329/bjch.v42i3.39271 ◽

2018 ◽

Vol 42 (3) ◽

pp. 155-158

Author(s):

AKMA Morshed ◽

S Islam ◽

K Alam

Keyword(s):

Early Childhood ◽

Case Report ◽

Germ Cell ◽

Rare Case ◽

Wilms Tumor ◽

Germ Cell Tumors ◽

Cystic Teratoma ◽

Cell Tumor ◽

Mediastinal Teratoma ◽

Rare Case Report

A teratoma of the mediastinum is an uncommon germ cell tumor. Five percent of germ cell tumors are extragonadally located and men are affected more than women .Most mediastinal teratoma produce no symptoms, but we are presenting a case which was present with respiratory distress in early childhood. Classical wilm’s tumor usually found within the kidney but rarely it can occur in extra renal situations. Combination of these two is not reported until today we have searched extensively. We are presenting a 26 month old boy with mediastinal cystic teratoma with right sided extra renal wilms’ tumor which may be the first reported case. Combined effort of various concern departments ensures the diagnosis and management of such a rare case. Bangladesh J Child Health 2018; VOL 42 (3) :155-158

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Intestinal Adenocarcinoma Arising from a Mature Cystic Teratoma

Case Reports in Pathology ◽

10.1155/2019/7894581 ◽

2019 ◽

Vol 2019 ◽

pp. 1-5

Author(s):

King Man Wan ◽

Forough Foroughi ◽

Rajni Bansal ◽

Martin K. Oehler

Keyword(s):

Germ Cell ◽

Incidence Rate ◽

Clinical Presentation ◽

Ovarian Neoplasms ◽

Germ Cell Tumour ◽

Cystic Teratoma ◽

Squamous Cell Carcinomas ◽

Mature Cystic Teratoma ◽

Histopathological Diagnosis ◽

Common Malignancy

Mature cystic teratomas are the most common ovarian germ cell tumour and account for 10–20% of all ovarian neoplasms. Malignant transformation of mature cystic teratomas is rare and has an incidence rate of less than 1%. The most common malignancy are squamous cell carcinomas. Here we present the case of an intestinal adenocarcinoma which is an exceedingly rare malignant entity arising within a mature cystic teratoma. Clinical presentation, imaging and histopathological diagnosis are discussed and previously presented cases in the literature reviewed.

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