scholarly journals De volta ao meio líquido: efeitos da intervenção de fisioterapia aquática realizada em prematuros

2019 ◽  
Vol 20 (6) ◽  
pp. 566-575
Author(s):  
Karize Rafaela Mesquita Novakoski ◽  
Silvia Regina Valderramas ◽  
Vera Lucia Israel ◽  
Bruna Yamaguchi ◽  
Marimar Goretti Andreazza
Keyword(s):  
Sleep Disturbances ◽  
Care Setting ◽  
Physiological Parameters ◽  
Warm Water ◽  
Sleep State ◽  
Physiological Variables ◽  
Neonatal Icu ◽  
Preterm Newborns ◽  
Birth Preterm

At birth, preterm newborns (PTNB) often require Neonatal-ICU hospitalization, which, despite being a care setting, also causes stress such as pain, sleep disturbances and wakefulness, and alterations of physiological parameters. The aim of this study was to analyze the effects of aquatic physiotherapy on pain, sleep disturbances and wakefulness, and physiological variables of PTNB in Neonatal-ICU. Pain, sleep disturbances and wakefulness, and alterations of physiological parameters were evaluated at three moments: 5 minutes before intervention, immediately after and 10 minutes after intervention. At intervention, participants were wrapped in soft fabric and immersed at shoulder level in warm water (36 °C to 37.5 °C). Sideways, forward, backward and rotational movements were performed. Twenty-two newborns participated in the study. The results obtained in relation to pain, sleep state and wakefulness showed significant improvements in reevaluations after intervention. Physiological variables also underwent significant changes and remained within normality parameters. The results indicate that aquatic physiotherapy is effective in reducing pain, improving sleep and wakefulness and physiological variables of PTNB in Neonatal-ICU.

102 Single-Prolonged Stress as a Model of PTSD in Mice: Effects on Sleep and Anxiety

SLEEP ◽  
2021 ◽  
Vol 44 (Supplement_2) ◽  
pp. A42-A42
Author(s):  
Katelyn Gutowsky ◽  
Carolyn Jones ◽  
Miranda Lim
Keyword(s):  
Rem Sleep ◽  
Sleep Disturbances ◽  
Sleep Problems ◽  
Power Spectra ◽  
Post Traumatic Stress ◽  
Sleep State ◽  
Single Prolonged Stress ◽  
Post Traumatic ◽  
And Control ◽  
Prolonged Stress

Abstract Introduction Sleep problems are common in humans with post-traumatic stress disorder (PTSD). Rapid eye movement (REM) sleep is involved in processing emotional memories; it is often disrupted in those with PTSD, and may be related to increased anxiety. Single prolonged stress (SPS) is a protocol used to model PTSD in rats, however little is known about how this model impacts sleep in mice. Prior research suggests SPS produces short term disturbances in REM sleep and increases in anxiety-like behavior, but further validation of this model is needed to understand how SPS impacts sleep and anxiety-like behaviors in mice specifically, as they have greater potential for transgenic manipulation Methods C57BL6/J mice underwent a SPS protocol in which they were tube-restrained for 2 hours, followed by a 15 minute forced swim in a group, ether exposure until loss of consciousness, and 10 days of social isolation. Following SPS, mice were tested for anxiety-like behavior in a light-dark box and sleep was measured from surgically implanted EEG and EMG leads. Time spent in wake, REM sleep, and non-REM sleep was quantified for 24 continuous hours in SPS and Control mice. Results There were no significant effects of SPS on the amount of time spent in any vigilance state, or in sleep-wake transitions. However, SPS-exposed mice showed significantly more anxiety-like behavior. EEG power spectra were analyzed in relevant frequency bands during each sleep state, and exploratory analyses were conducted Conclusion Minimal effects on sleep macroarchitecture were seen in mice 10 days after SPS. It is possible that sleep disturbances seen immediately after trauma exposure (such as in prior studies in rats) may have diminished over time. Further studies will need to include additional timepoints and analysis of sleep microarchitecture following SPS, and in other mouse models of PTSD, in order to more comprehensively examine changes in sleep. Support (if any) VA CDA #IK2 BX002712, Portland VA Research Foundation, Medical Research Foundation

Rehabilitation in Neurocritical Care

2018 ◽  
pp. 286-296
Author(s):  
Michael E. Reznik ◽  
Amy K. Wagner
Keyword(s):  
Sleep Disturbances ◽  
Care Setting ◽  
Clinical Care ◽  
Management Strategies ◽  
Acquired Brain Injury ◽  
Medical Complications ◽  
Acute Care Setting ◽  
Rehabilitation Team ◽  
Bowel And Bladder Dysfunction ◽  
Language Pathology

Rehabilitation is a process that should begin in the neurointensive care unit. Once a rough prognosis has been made within the context of goals of care discussions, and a decision has been made to proceed with measures geared toward recovery, the focus of clinical care should begin to shift toward the transition to rehabilitation in order to maximize functional gains. In the acute care setting, this necessitates the collaboration of a multidisciplinary team, including physical medicine and rehabilitation, physical and occupational therapy, speech and language pathology, neuropsychology, social work, and nursing. Among the most challenging issues facing intensivists and the rehabilitation team in the critical care setting is the management of the various rehabilitation-related medical complications associated with acquired brain injury, including decreased level of arousal, agitation, sleep disturbances, depression, dysautonomia, bowel and bladder dysfunction, and spasticity. This chapter highlights current management strategies for dealing with these issues.

scholarly journals Quantitative Assessment of the Physiological Parameters Influencing QT Interval Response to Medication: Application of Computational Intelligence Tools

2018 ◽  
Vol 2018 ◽  
pp. 1-11
Author(s):  
Sebastian Polak ◽  
Barbara Wiśniowska ◽  
Aleksander Mendyk ◽  
Adam Pacławski ◽  
Jakub Szlęk
Keyword(s):  
Computational Intelligence ◽  
Qt Interval ◽  
Physiological Parameters ◽  
Programming Technique ◽  
Physiological Variables ◽  
Pr Interval ◽  
Wave Morphology ◽  
Heart Electrophysiology ◽  
Interval Response

Human heart electrophysiology is complex biological phenomenon, which is indirectly assessed by the measured ECG signal. ECG trace is further analyzed to derive interpretable surrogates including QT interval, QRS complex, PR interval, and T wave morphology. QT interval and its modification are the most commonly used surrogates of the drug triggered arrhythmia, but it is known that the QT interval itself is determined by other nondrug related parameters, physiological and pathological. In the current study, we used the computational intelligence algorithms to analyze correlations between various simulated physiological parameters and QT interval. Terfenadine given concomitantly with 8 enzymatic inhibitors was used as an example. The equation developed with the use of genetic programming technique leads to general reasoning about the changes in the prolonged QT. For small changes of the QT interval, the drug-related IKr and ICa currents inhibition potentials have major impact. The physiological parameters such as body surface area, potassium, sodium, and calcium ions concentrations are negligible. The influence of the physiological variables increases gradually with the more pronounced changes in QT. As the significant QT prolongation is associated with the drugs triggered arrhythmia risk, analysis of the role of physiological parameters influencing ECG seems to be advisable.

The factor structure of the General Health Questionnaire (GHQ): a scaled version for general practice in Spain

2006 ◽  
Vol 21 (7) ◽  
pp. 478-486 ◽  
Author(s):  
J.D. Molina ◽  
C. Andrade-Rosa ◽  
S. González-Parra ◽  
H. Blasco-Fontecilla ◽  
M.A. Real ◽  
...  
Keyword(s):  
General Health ◽  
Sleep Disturbances ◽  
Care Setting ◽  
Primary Care Setting ◽  
Sleep Problems ◽  
General Health Questionnaire ◽  
Health Questionnaire ◽  
Predictive Values ◽  
English Population ◽  
Components Analysis

AbstractBackgroundThe 28-item version of the General Health Questionnaire (GHQ-28) developed by Goldberg and Hillier in 1979 is constructed on the basis of a principal components analysis of the GHQ-60. When used on a Spanish population, a translation of the GHQ-28 developed for an English population may lead to worse predictive values.MethodsWe used our Spanish sample to replicate the entire process of construction of the GHQ-28 administered in a primary-care setting.ResultsTwo shorter versions were proposed: one with six scales and 30 items, and the other with four scales and 28 items.ConclusionsThe resulting GHQ-28 was a successful adaptation for use on the Spanish sample. When compared with the original version, only 21 items were the same. Moreover, contrary to the English version, which groups sleep problems and anxiety in the same scale, a scale with items related exclusively to ‘Sleep disturbances’ was found.

scholarly journals Sleep Disorders in Patients with Psoriatic Arthritis

2021 ◽  
Vol 1 (2) ◽  
Author(s):  
Mariana Castanho Risso
Keyword(s):  
Metabolic Syndrome ◽  
Psoriatic Arthritis ◽  
Sleep Disorders ◽  
Sleep Disturbances ◽  
Public Health Issue ◽  
Berlin Questionnaire ◽  
Sleep State ◽  
Simultaneous Control ◽  
Sleep Assessment

Sleep disorders are currently a major public health issue in Brazil, due to its high incidence and difficult diagnosis, identification of type and treatment.1 Rheumatic disorders have been associated with changes in sleep state, which cause reduction in quality of life, eventually reduced by the chronic inflammatory process of the primary disease.2–6 This study aimed to identify and describe the existence of sleep disturbances in patients with psoriatic arthritis, as well as to verify possible association of sleep disorders with metabolic syndrome and other parameters in these individuals. Thirty one patients with psoriatic arthritis from a Rheumatology Outpatient Clinic were analyzed. Three sleep assessment questionnaires were employed: Pittsburgh Sleep Quality Index (PSQI), Epworth Sleepiness Scale (EPW) and The Berlin Questionnaire (BQ). Sleep walking or talking were also inquired as a complementary scale. Sociodemographic variables and the presence of hypertension, obesity, diabetes, dyslipidemia and metabolic syndrome have also been investigated. On average, sleep disorders were found in 54.83% of the studied patients (64.5% from PSQI, 51.6% from EPW and 48.4% from Berlin) and around 70% of sleep disorders in patients with simultaneous diagnosis of metabolic syndrome and psoriatic arthritis. From these results, it is notable that sleep disorders are common in patients diagnosed with psoriatic arthritis. Thus, this pathology demands greater attention in clinical practice and search for ideal and complete therapy, in addition to simultaneous control of arthritis, sleep, hypertension, dyslipidemia and obesity.

scholarly journals Actigraphic and Self-reported Sleep in Traffic Accident Victims

2021 ◽  
pp. 1-6
Author(s):  
V. Renner ◽  
M. Keller ◽  
M. Beuth ◽  
W.T. Roth ◽  
K. Petrowski
Keyword(s):  
Sleep Quality ◽  
Traffic Accident ◽  
Sleep Disturbances ◽  
Sleep Onset ◽  
Group Differences ◽  
Sleep State ◽  
Subjective Sleep Quality ◽  
Sleep Log ◽  
Healthy Participants

Background: Some accident victims report poorer sleep during the months after the trauma, which may double the risk for and is a mediator of the development of a PTSD. Furthermore, subjective and objective sleep measures are often discrepant in PTSD-patients, which is why a ‘sleep state misperception’ of PTSD patients is often hypothesized. Objective: The goal of this study is to assess differences in sleep quality in victims of a traffic accident compared to healthy participants without an accident history as well as differences between objective and subjective sleep quality measures. Methods: We recruited 25 hospitalized accident victims within ten days of an accident and 31 age and sex-matched controls without an accident history. Three months later, participants were given a structured clinical interview (SCID), they completed the Pittsburg Sleep Quality Index (PSQI) for the previous two weeks, wore a wrist actigraph, and kept a sleep log for two consecutive nights. Results: At the three-month follow-up, none of the victims met the criteria for any kind of mental disorder, but scored higher on the Posttraumatic Diagnostic Scale. On the PSQI they reported slightly worse sleep than controls for the previous two weeks, although sleep log and actigraphy measures on the two recording nights showed no group differences. Actigraphy measures showed shorter sleep onset latencies compared to log measures. Conclusions: The accident victims suffered only minimal sleep disturbances three months later. The assumption of a ‘sleep state misperception’ in traffic accident victims is questioned by these results.

scholarly journals Refined versus Extra Virgin Olive Oil High-Fat Diet Impact on Intestinal Microbiota of Mice and Its Relation to Different Physiological Variables

2019 ◽  
Vol 7 (2) ◽  
pp. 61 ◽  
Author(s):  
Nieves Martínez ◽  
Isabel Prieto ◽  
Marina Hidalgo ◽  
Ana Segarra ◽  
Ana Martínez-Rodríguez ◽  
...  
Keyword(s):  
Olive Oil ◽  
Intestinal Microbiota ◽  
High Fat Diet ◽  
Virgin Olive Oil ◽  
Extra Virgin Olive Oil ◽  
Physiological Parameters ◽  
Minor Components ◽  
High Fat ◽  
Physiological Variables ◽  
Physiological Benefits

Extra virgin olive oil (EVOO) has been reported to have a distinct influence on gut microbiota in comparison to other fats, with its physiological benefits widely studied. However, a large proportion of the population consumes olive oil after a depurative process that not only mellows its taste, but also deprives it of polyphenols and other minority components. In this study, we compare the influence on the intestinal microbiota of a diet high in this refined olive oil (ROO) with other fat-enriched diets. Swiss Webster mice were fed standard or a high-fat diet enriched with EVOO, ROO, or butter (BT). Physiological parameters were also evaluated. At the end of the feeding period, DNA was extracted from feces and the 16S rRNA was pyrosequenced. The group fed ROO behaved differently to the EVOO group in half the families with statistically significant differences among the diets, with higher comparative levels in three families—Desulfovibrionaceae, Spiroplasmataceae, and Helicobacteraceae—correlating with total cholesterol. These results are again indicative of a link between specific diets, certain physiological parameters and the prevalence of some taxa, but also support the possibility that polyphenols and minor components of EVOO are involved in some of the proposed effects of this fat through the modulation of the intestinal microbiota

scholarly journals Identifying physiological origins of baroreflex dysfunction in salt-sensitive hypertension in the Dahl SS rat

2010 ◽  
Vol 42 (1) ◽  
pp. 23-41 ◽  
Author(s):  
Scott M. Bugenhagen ◽  
Allen W. Cowley ◽  
Daniel A. Beard
Keyword(s):  
Heart Rate ◽  
Control System ◽  
Physiological Parameters ◽  
High Salt ◽  
Physiological Mechanisms ◽  
Baroreflex Control ◽  
High Salt Diet ◽  
Salt Diet ◽  
Physiological Variables ◽  
Salt Sensitive Hypertension

Salt-sensitive hypertension is known to be associated with dysfunction of the baroreflex control system in the Dahl salt-sensitive (SS) rat. However, neither the physiological mechanisms nor the genomic regions underlying the baroreflex dysfunction seen in this rat model are definitively known. Here, we have adopted a mathematical modeling approach to investigate the physiological and genetic origins of baroreflex dysfunction in the Dahl SS rat. We have developed a computational model of the overall baroreflex heart rate control system based on known physiological mechanisms to analyze telemetry-based blood pressure and heart rate data from two genetic strains of rat, the SS and consomic SS.13BN, on low- and high-salt diets. With this approach, physiological parameters are estimated, unmeasured physiological variables related to the baroreflex control system are predicted, and differences in these quantities between the two strains of rat on low- and high-salt diets are detected. Specific findings include: a significant selective impairment in sympathetic gain with high-salt diet in SS rats and a protection from this impairment in SS.13BN rats, elevated sympathetic and parasympathetic offsets with high-salt diet in both strains, and an elevated sympathetic tone with high-salt diet in SS but not SS.13BN rats. In conclusion, we have associated several important physiological parameters of the baroreflex control system with chromosome 13 and have begun to identify possible physiological mechanisms underlying baroreflex impairment and hypertension in the Dahl SS rat that may be further explored in future experimental and modeling-based investigation.

scholarly journals PARÂMETROS FISIOLÓGICOS DO MILHO CULTIVADO SOB ADUBAÇÃO ORGANOMINERAL DE NPK, ÁGUA AMARELA E MANIPUEIRA

Irriga ◽  
2019 ◽  
Vol 24 (2) ◽  
pp. 444-459
Author(s):  
Jailton Garcia Ramos ◽  
Vera Lúcia Antunes De Lima ◽  
Ronaldo do Nascimento ◽  
Narcísio Cabral De Araújo ◽  
Rafaela Felix Basílio Guimarães ◽  
...  
Keyword(s):  
Human Urine ◽  
Physiological Parameters ◽  
Soluble Solids ◽  
Chlorophyll B ◽  
Organic Fertilization ◽  
Hybrid Corn ◽  
Physiological Variables ◽  
Solids Concentration ◽  
Cassava Wastewater ◽  
Soluble Solids Concentration

PARÂMETROS FISIOLÓGICOS DO MILHO CULTIVADO SOB ADUBAÇÃO ORGANOMINERAL DE NPK, ÁGUA AMARELA E MANIPUEIRA     JAILTON GARCIA RAMOS1; VERA LÚCIA ANTUNES DE LIMA2; RONALDO DO NASCIMENTO3; NARCÍSIO CABRAL DE ARAÚJO4; RAFAELA FÉLIX BASÍLIO GUIMARÃES5 E MARIANA DE OLIVEIRA PEREIRA6   1 Unidade Acadêmica de Engenharia Agrícola, Universidade Federal de Campina Grande, campus Campina Grande, Rua Aprígio Veloso, 882 - Universitário, 58429-900, Campina Grande, Paraíba, Brasil.  [email protected]; 2 Unidade Acadêmica de Engenharia Agrícola, Universidade Federal de Campina Grande, campus Campina Grande, Rua Aprígio Veloso, 882 - Universitário, 58429-900, Campina Grande, Paraíba, Brasil. [email protected]; 3 Unidade Acadêmica de Engenharia Agrícola, Universidade Federal de Campina Grande, campus Campina Grande, Rua Aprígio Veloso, 882 - Universitário, 58429-900, Campina Grande, Paraíba, Brasil. [email protected]; 4 Centro de Formação em Tecno-ciências e Inovações, Universidade Federal do Sul da Bahia, , Campus Itabuna, Rodovia de Acesso para Itabuna, km 39 - Ferradas, 45613-204, Itabuna, Bahia, Brasil. [email protected]; 5 Unidade Acadêmica de Engenharia Agrícola, Universidade Federal de Campina Grande, campus Campina Grande, Rua Aprígio Veloso, 882 - Universitário, 58429-900, Campina Grande, Paraíba, Brasil. [email protected]; 6 Unidade Acadêmica de Engenharia Agrícola, Universidade Federal de Campina Grande, campus Campina Grande, Rua Aprígio Veloso, 882 - Universitário, 58429-900, Campina Grande, Paraíba, Brasil. [email protected].     1 RESUMO   Objetivou-se neste trabalho, avaliar parâmetros fisiológicos do milho híbrido AG 1051 cultivado em ambiente protegido em solo fertilizado com urina humana e manipueira. O delineamento experimental foi inteiramente casualisado com quatorze tratamentos e quatro repetições, totalizando 56 parcelas. Os tratamentos foram: T1 (NPK), T2 (470 mL), T3 (670 mL), T4 (870 mL), T5 (1070 mL), T6 (1270 mL), T7 (1470 mL), T8 (F - NPK), T9 (F - 470 mL), T10 (F – 670 mL), T11 (F – 870 mL), T12 (F – 1070 mL), T13 (F – 1270 mL) e T14 (F – 1470 mL). Os volumes aplicados foram a combinação de urina humana + manipueira tratadas como adubação de fundação e fertirrigação (F).  Foram avaliadas as variáveis de pigmento (clorofilas A, B, total e carotenóides), SPAD e °Brix. O tratamento T1 promoveu incremento de 43,94% no índice SPAD em relação ao T2. Mariores incrementos na concentração de sólidos solúveis totais foram obtidos para T1, T5, T7 e T8. O tratmento T13 promoveu valores máximos de clorofila A e total de 3843,703 e 5479,152 μgg-1 respectivamente. E para T14 os rendimentos máximos foram para as variáveis clorofila B e carotenoides (2805,197 e 333440,042 μgg-1). Os tratamentos influenciam positivamente todas as variáveis fisiológicas.   Palavras–chave: ecossanemamento, urina humana, biofertilizante líquido, reuso agrícola         RAMOS, J.G.; DE LIMA, V. L. A.; DO NASCIMENTO, R.; DE ARAÚJO, N. C.; GUIMARÃES, R. F. B.; PEREIRA, M. O. PHYSIOLOGICAL PARAMETERS OF CORN CULTIVATED UNDER ORGANIC FERTILIZATION OF NPK, YELLOW WATER AND CASSAVA WASTEWATER      2 ABSTRACT   The aim of this study was to evaluate the physiological parameters of the hybrid corn AG 1051 grown in a protected environment in soil fertilized with human urine and treated cassava wastewater. The experimental design was completely randomized with fourteen treatments and four replications, thus totaling 56 experimental units. The treatments were as follows: T1 (NPK), T2 (470 mL), T3 (670 mL), T4 (870 mL), T5 (1070 ml), T6 (1270 ml), T7 (1470 mL), T8 (F - NPK), T9 (F - 470 ml), T10 (F - 670 ml), T11 (F - 870 ml), T12 (F - 1070 ml), T13 (F - 1270) and T14 (F - 1470). The volume applied is the combination of human urine + cassava wastewater treated as foundation fertilization and fertigation (F). The production of chlorophylls A, B, total and carotenoids, SPAD and °Brix were evaluated. The T1 treatment promoted an increase of 43.94% in the SPAD index in relation to T2. Height increases in total soluble solids concentration were obtained for T1, T5, T7 and T8. The T13 treatment promoted maximum values of chlorophyll A and total of 3843.703 and 5479.152 μgg-1 respectively. For T14 the maximum yields were for the variables chlorophyll B and carotenoids (2805.197 and 333440.042 μgg-1). Treatments positively influence all physiological variables.   Keywords: eco sanitation, human urine, liquid biofertilizer, reuse agriculture.

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