Evaluation of Changes in Anxiety and Depression Symptoms, and Sexual Functions in Patients Receiving Antidepressants; 3 Months-Long Naturalistic Follow-Up Study

Background: Motor vehicle crashes (MVCs) are leading contributors to the global burden of disease. Patients attending accident and emergency (A&E) after an MVC may develop symptoms of posttraumatic stress disorder (PTSD). There is evidence that brief cognitive behavioural therapy (B-CBT) can be effective in treating PTSD; however, there are few studies of the use of B-CBT to treat PTSD in MVC survivors. Aims: This study examined the effects of B-CBT and a self-help program on the severity of psychological symptoms in MVC survivors at risk of developing PTSD. Method: Sixty participants who attended A&E after a MVC were screened for PTSD symptoms and randomized to a 4-weekly session B-CBT or a 4-week self-help program (SHP) booklet treatment conditions. Psychological assessments were completed at baseline (1-month post-MVC) and posttreatment (3- and 6-month follow-ups) by utilizing Impact of Event Scale-Revised (IES-R) and Hospital Anxiety and Depression Scale (HADS). Results: There were significant improvements in the measures of anxiety, depression, and PTSD symptoms over time. Participants treated with B-CBT showed greater reductions in anxiety at 3-month and 6-month follow-ups, and in depression at 6-month follow-up. A comparison of effect size favoured B-CBT for the reduction of anxiety and depression symptoms measured by HADS. A high level of pretreatment anxiety and depression were predictive of negative outcome at 6-month follow-up in the SHP condition. There was no differential effect on PTSD symptoms measured by IES-R. Conclusions: This trial supports the efficacy of providing B-CBT as a preventive strategy to improve psychological symptoms after an MVC.

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What do predict anxiety and depression in breast cancer patients? A follow-up study

Social Psychiatry and Psychiatric Epidemiology ◽

10.1007/s00127-009-0068-7 ◽

2009 ◽

Vol 45 (3) ◽

pp. 355-361 ◽

Cited By ~ 120

Author(s):

Mariam Vahdaninia ◽

Sepideh Omidvari ◽

Ali Montazeri

Keyword(s):

Breast Cancer ◽

Cancer Patients ◽

Anxiety And Depression ◽

Breast Cancer Patients ◽

Follow Up Study

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Anxiety and depression in patients with head and neck cancer: 6-month follow-up study

Neuropsychiatric Disease and Treatment ◽

10.2147/ndt.s103203 ◽

2016 ◽

pp. 1029 ◽

Cited By ~ 24

Author(s):

Yi-Shan Wu ◽

Pao-Yen Lin ◽

Chih-Yen Chien ◽

Fu-Min Fang ◽

Nien-Mu Chiu ◽

...

Keyword(s):

Head And Neck Cancer ◽

Head And Neck ◽

Neck Cancer ◽

Anxiety And Depression ◽

Follow Up Study

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The effect of jaw exercises on anxiety and depression in patients with head and neck cancer receiving radiotherapy: Prospective 2‐year follow‐up study

Head & Neck ◽

10.1002/hed.26012 ◽

2019 ◽

Vol 42 (2) ◽

pp. 330-335 ◽

Cited By ~ 1

Author(s):

Susan Aghajanzadeh ◽

Therese Karlsson ◽

Lisa Tuomi ◽

Caterina Finizia

Keyword(s):

Head And Neck Cancer ◽

Head And Neck ◽

Neck Cancer ◽

Anxiety And Depression ◽

Follow Up Study

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Anxiety, Depression, and Colorectal Cancer Survival: Results from Two Prospective Cohorts

Journal of Clinical Medicine ◽

10.3390/jcm9103174 ◽

2020 ◽

Vol 9 (10) ◽

pp. 3174

Author(s):

Claudia Trudel-Fitzgerald ◽

Shelley S. Tworoger ◽

Xuehong Zhang ◽

Edward L. Giovannucci ◽

Jeffrey A. Meyerhardt ◽

...

Keyword(s):

Colorectal Cancer ◽

Fixed Effects ◽

Cox Regression ◽

Sensitivity Analyses ◽

Disease Stage ◽

Health Study ◽

Anxiety And Depression ◽

Depression Symptoms ◽

Standard Deviation Increase

Given the unalterable nature of most risk factors for colorectal cancer (CRC) survival (e.g., disease stage), identifying modifiable determinants is critical. We investigated whether anxiety and depression were related to CRC survival using data from the Nurses’ Health Study (NHS) and Health Professional Follow-up Study (HPFS). Participants who received a CRC diagnosis and provided information about anxiety (nNHS = 335; nHPFS = 232) and depression (nNHS = 893; nHPFS = 272) within 4 years of diagnosis were included. Cox regression models estimated hazard ratios (HR) and 95% confidence intervals (CI) of overall mortality, while controlling for covariates (sociodemographics, cancer characteristics, and lifestyle factors). Pooled risk estimates were derived from fixed effects meta-analyses of the cohorts. Among 1732 CRC patients, 814 deaths occurred during the 28-year follow-up. Each 1 standard deviation increase in anxiety or depression symptoms was associated with a similar 16% higher mortality risk (anxiety: 95% CI = 1.05–1.29; depression: 95% CI = 1.07–1.26). Comparable results were observed across all sensitivity analyses (introducing a 1-year lag, restricting to CRC-related mortality, considering potential behavioral pathways) and stratified models (cancer stage, sex). Our findings suggest greater anxiety and depression symptoms can not only impede adherence to healthy habits and reduce quality of life in cancer patients but could also be a marker for accelerated CRC progression.

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Anxiety and depression symptoms in Danish patients with an implantable cardioverter-defibrillator: prevalence and association with indication and sex up to 2 years of follow-up (data from the national DEFIB-WOMEN study)

EP Europace ◽

10.1093/europace/euaa176 ◽

2020 ◽

Vol 22 (12) ◽

pp. 1830-1840

Author(s):

Vivi Skibdal Frydensberg ◽

Jens Brock Johansen ◽

Sören Möller ◽

Sam Riahi ◽

Sonja Wehberg ◽

...

Keyword(s):

Implantable Cardioverter Defibrillator ◽

Depression Scale ◽

Anxiety And Depression ◽

Depression Symptoms ◽

Depression Symptom ◽

Icd Implantation ◽

Cardioverter Defibrillator ◽

Time Points ◽

Mixed Modelling

Abstract Aims To investigate (i) the prevalence of anxiety and depression and (ii) the association between indication for implantable cardioverter-defibrillator (ICD) implantation and sex in relation to anxiety and depression up to 24 months’ follow-up. Methods and results Patients with a first-time ICD, participating in the national, multi-centre, prospective DEFIB-WOMEN study (n = 1496; 18% women) completed the Hospital Anxiety and Depression Scale at baseline, 3, 6, 12, and 24 months. Data were analysed using linear mixed modelling for longitudinal data. Patients with a secondary prophylactic indication (SPI) had higher mean anxiety scores than patients with a primary prophylactic indication (PPI) at baseline, 3, and 12 months and higher mean depression scores at all-time points, except at 24 months. Women had higher mean anxiety scores as compared to men at all-time points; however, only higher mean depression scores at baseline. Overall, women with SPI had higher anxiety and depression symptom scores than men with SPI. Symptoms decreased over time in both women and men. From baseline to follow-up, the prevalence of anxiety (score ≥8) was highest in patients with SPI (13.3–20.2%) as compared to patients with PPI (range 10.0–14.7%). The prevalence of depression was stable over the follow-up period in both groups (range 8.5–11.1%). Conclusion Patients with a SPI reported higher anxiety and depression scores as compared to patients with PPI. Women reported higher anxiety scores than men, but only higher depression scores at baseline. Women with SPI reported the highest anxiety and depression scores overall.

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