scholarly journals Current Status of Lung Cancer and Surgery Based on Studies Using a Nationwide Database

2021 ◽  
Author(s):  
Dohun Kim ◽  
Jung-Won Lee
Keyword(s):  
Lung Cancer ◽  
Current Status ◽  
Nationwide Database

scholarly journals Current Status and Future Perspectives of Liquid Biopsy in Small Cell Lung Cancer

Biomedicines ◽  
2021 ◽  
Vol 9 (1) ◽  
pp. 48
Author(s):  
Patricia Mondelo-Macía ◽  
Jorge García-González ◽  
Luis León-Mateos ◽  
Adrián Castillo-García ◽  
Rafael López-López ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Liquid Biopsy ◽  
Small Cell ◽  
New Drugs ◽  
Current Status ◽  
Small Cell Lung ◽  
Tumor Biopsy ◽  
Future Utility

Approximately 19% of all cancer-related deaths are due to lung cancer, which is the leading cause of mortality worldwide. Small cell lung cancer (SCLC) affects approximately 15% of patients diagnosed with lung cancer. SCLC is characterized by aggressiveness; the majority of SCLC patients present with metastatic disease, and less than 5% of patients are alive at 5 years. The gold standard of SCLC treatment is platinum and etoposide-based chemotherapy; however, its effects are short. In recent years, treatment for SCLC has changed; new drugs have been approved, and new biomarkers are needed for treatment selection. Liquid biopsy is a non-invasive, rapid, repeated and alternative tool to the traditional tumor biopsy that could allow the most personalized medicine into the management of SCLC patients. Circulating tumor cells (CTCs) and cell-free DNA (cfDNA) are the most commonly used liquid biopsy biomarkers. Some studies have reported the prognostic factors of CTCs and cfDNA in SCLC patients, independent of the stage. In this review, we summarize the recent SCLC studies of CTCs, cfDNA and other liquid biopsy biomarkers, and we discuss the future utility of liquid biopsy in the clinical management of SCLC.

Circulating Biomarkers in Non–Small-Cell Lung Cancer: Current Status and Future Challenges

2016 ◽  
Vol 17 (6) ◽  
pp. 507-516 ◽  
Author(s):  
Alexios Matikas ◽  
Konstantinos N. Syrigos ◽  
Sofia Agelaki
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Small Cell ◽  
Current Status ◽  
Circulating Biomarkers ◽  
Small Cell Lung ◽  
Future Challenges

Worldwide Overview of the Current Status of Lung Cancer Diagnosis and Treatment

2012 ◽  
Vol 136 (12) ◽  
pp. 1478-1481 ◽  
Author(s):  
Paul A. Bunn
Keyword(s):  
Lung Cancer ◽  
Cancer Mortality ◽  
Kinase Inhibitors ◽  
False Positive Rate ◽  
Lung Cancer Mortality ◽  
Current Status ◽  
Advanced Lung Cancer ◽  
Lung Cancer Diagnosis ◽  
Positive Rate ◽  
Inhaled Prostacyclin

Lung cancer is the leading worldwide cause of cancer deaths. Smoking is the dominant cause of lung cancer and smoking cessation is the established method to reduce lung cancer mortality. While lung cancer risk is reduced in former smokers, they have a lifelong increase in risk, compared to never-smokers. Novel chemoprevention strategies, such as oral or inhaled prostacyclin analogs, hold promise for these subjects. Low-dose spiral computed tomography screening reduced lung cancer mortality by 20% in high-risk heavy smokers older than 50 years. However, the high false-positive rate (96%) means that screened patients required controlled follow-up in experienced centers. An increasing percentage of patients with advanced lung cancer have molecular drivers in genes for which oral tyrosine kinase inhibitors have been developed.

Current Status of Mammalian Target of Rapamycin Inhibitors in Lung Cancer

2005 ◽  
Vol 7 ◽  
pp. S13-S18 ◽  
Author(s):  
Carlos Gómez-Martín ◽  
Belen Rubio-Viqueira ◽  
Manuel Hidalgo
Keyword(s):  
Lung Cancer ◽  
Mammalian Target Of Rapamycin ◽  
Target Of Rapamycin ◽  
Current Status

scholarly journals Current Status and Perspective of Call Request in Lung Cancer Screening

2017 ◽  
Vol 28 ◽  
pp. ix109
Author(s):  
Tatsuo Kimura ◽  
Shinya Fukumoto ◽  
Hiroyasu Morikawa ◽  
Akemi Nakano ◽  
Fumio Tanaka ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cancer Screening ◽  
Lung Cancer Screening ◽  
Current Status ◽  
Call Request
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