Usefulness and limitation of the body surface VAT (ventricular activation time) isochrone mapping for inferring the excitation spread disorders in the ventricles

This study describes a noninvasive method for detecting delayed ventricular activation, caused by ischemia, on the body surface. Signal averaging and a newly developed high-pass digital filter were used. The filter has the property that it does not create an artifact or ring after the QRS complex ends, thereby allowing the detection of microvolt-level potentials that occur immediately after the QRS complex. Eleven dogs were studied before and during acute ischemia induced by coronary artery ligation and latex embolization. The ischemic region was mapped with bipolar electrodes and, after the chest was rapidly closed, signal-averaged recordings were made from the body surface. Repeated cycles of ventricular mapping and signal averaging were performed. In each dog, delayed and fractionated electrograms were recorded directly from the ischemic epicardium that lasted a maximum of 118 +/- 18 ms after QRS onset. The duration of the ventricular electrograms varied with time. Whenever delayed epicardial electrograms were recorded, filtered signal-averaged leads showed microvolt-level potentials early in the S-T segment that were continuous with the QRS complex. The duration of ventricular activation, as measured from the bipolar electrograms and from the filtered signal-averaged leads, correlated well (r = 0.93, P less than 0.001). Because of the absence of filter ringing, low-level potentials could be detected less than 40 ms after the QRS complex ended. This study demonstrates that microvolt-level potentials arising from delayed ventricular activation can be reliably detected on the body surface, even when they occur just after the QRS complex.

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The QRS electrocardiogram, epicardiogram, vectorcardiogram and ventricular excitation of swine

American Journal of Physiology-Legacy Content ◽

10.1152/ajplegacy.1960.198.3.537 ◽

1960 ◽

Vol 198 (3) ◽

pp. 537-542 ◽

Cited By ~ 19

Author(s):

Robert L. Hamlin

Keyword(s):

Right Ventricular ◽

Body Surface ◽

The Body ◽

Ventricular Free Wall ◽

Activation Process ◽

Free Wall ◽

Right Ventricular Free Wall ◽

Surface Potentials ◽

Ventricular Activation ◽

Three Components

The ventricular activation process of normal pigs as estimated qualitatively from body surface potentials and epicardial electrograms is similar to that accurately described for the dog. Ventricular excitation may be divided sequentially into three components: interventricular septal from left to right, ventricular free-wall from endocardium to epicardium, and septal and ventricular basilar in an apico-basilar direction. The differences between the body surface potentials recorded from the dog and from the pig lies in the greater dorsal magnitude of the terminal basilar forces in the pig.

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Confirmation of a new technique for detecting slow ventricular activation on the body surface

The American Journal of Cardiology ◽

10.1016/0002-9149(81)91027-4 ◽

1981 ◽

Vol 47 ◽

pp. 488 ◽

Cited By ~ 5

Author(s):

Michael B. Simson ◽

David E. Euler ◽

Eric L. Michelson ◽

Rita Falcone ◽

Joseph F. Spear ◽

...

Keyword(s):

Body Surface ◽

The Body ◽

New Technique ◽

Ventricular Activation ◽

A New Technique

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A Comparison of Body Surface Laplacian and Potential Maps During Paced Ventricular Activation

Methods of Information in Medicine ◽

10.1055/s-0038-1636846 ◽

1997 ◽

Vol 36 (04/05) ◽

pp. 336-339 ◽

Cited By ~ 5

Author(s):

K. Ono ◽

H. Hosaka ◽

B. He

Keyword(s):

Electrical Activity ◽

Body Surface ◽

The Body ◽

Surface Laplacian ◽

Cardiac Electrical Activity ◽

Torso Model ◽

Body Surface Potential Maps ◽

Ventricular Activation ◽

Body Surface Potential ◽

Ventricular Activity

Abstract:The objective of this study is to evaluate the spatial resolution of body surface Laplacian maps (BSLMs) in localizing ventricular electrical activity by means of computer simulation. A 3-D computer heart-torso model was used to simulate cardiac electrical activity and the body surface maps. A two-site pacing protocol was used to generate two simultaneously activated myocardial events on the anterior epicardial wall and the anterior endocardial wall. Following the pacing, the BSLMs and the body surface potential maps (BSPMs) were calculated and compared with the known activation pattern. As a result, the BSLMs showed superior resolution than the BSPMs for localized initial ventricular activity. In summary, the present study suggests that body surface Laplacian mapping may provide a useful methodology for the clinical diagnosis of cardiac electrical abnormalities.

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The Role of Computer Modeling in Electrocardiography

Methods of Information in Medicine ◽

10.1055/s-0038-1634809 ◽

1990 ◽

Vol 29 (04) ◽

pp. 282-288 ◽

Cited By ~ 2

Author(s):

A. van Oosterom

Keyword(s):

Electrical Activity ◽

Computer Modeling ◽

Body Surface ◽

Electrical Current ◽

The Body ◽

Volume Conductor ◽

Current Generator ◽

Cardiac Electrical Activity ◽

Source Models

AbstractThis paper introduces some levels at which the computer has been incorporated in the research into the basis of electrocardiography. The emphasis lies on the modeling of the heart as an electrical current generator and of the properties of the body as a volume conductor, both playing a major role in the shaping of the electrocardiographic waveforms recorded at the body surface. It is claimed that the Forward-Problem of electrocardiography is no longer a problem. Several source models of cardiac electrical activity are considered, one of which can be directly interpreted in terms of the underlying electrophysiology (the depolarization sequence of the ventricles). The importance of using tailored rather than textbook geometry in inverse procedures is stressed.

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The use of Body Surface Index as a Better Clinical Health indicators Compare to Body Mass Index and Body Surface Area for Clinical Application

International Journal of Scientific Research in Science Engineering and Technology ◽

10.32628/ijsrset2184117 ◽

2018 ◽

pp. 131-136

Author(s):

Shirazu I. ◽

Theophilus. A. Sackey ◽

Elvis K. Tiburu ◽

Mensah Y. B. ◽

Forson A.

Keyword(s):

Surface Area ◽

Body Surface Area ◽

Clinical Application ◽

Body Surface ◽

Body Height ◽

Health Indicators ◽

The Body ◽

Body Parameters ◽

The Relationship ◽

Individual Body

The relationship between body height and body weight has been described by using various terms. Notable among them is the body mass index, body surface area, body shape index and body surface index. In clinical setting the first descriptive parameter is the BMI scale, which provides information about whether an individual body weight is proportionate to the body height. Since the development of BMI, two other body parameters have been developed in an attempt to determine the relationship between body height and weight. These are the body surface area (BSA) and body surface index (BSI). Generally, these body parameters are described as clinical health indicators that described how healthy an individual body response to the other internal organs. The aim of the study is to discuss the use of BSI as a better clinical health indicator for preclinical assessment of body-organ/tissue relationship. Hence organ health condition as against other body composition. In addition the study is `also to determine the best body parameter the best predict other parameters for clinical application. The model parameters are presented as; modeled height and weight; modelled BSI and BSA, BSI and BMI and modeled BSA and BMI. The models are presented as clinical application software for comfortable working process and designed as GUI and CAD for use in clinical application.

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Hydro-Thermodynamics of a Liquid Film with CRystals on the Body Surface in an Air Flow Containing Ice Particles

Прикладная механика и техническая физика ◽

10.15372/pmtf20170211 ◽

2017 ◽

Keyword(s):

Liquid Film ◽

Body Surface ◽

Air Flow ◽

The Body ◽

Ice Particles

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Mannose-binding C-type lectins as defense molecules on the body surface of the sea urchin Pseudocentrotus depressus

Developmental & Comparative Immunology ◽

10.1016/j.dci.2020.103915 ◽

2021 ◽

Vol 116 ◽

pp. 103915

Author(s):

Chihiro Iiyama ◽

Fuyu Yoneda ◽

Masaya Tsutsumi ◽

Shigeyuki Tsutsui ◽

Osamu Nakamura

Keyword(s):

Sea Urchin ◽

Body Surface ◽

The Body ◽

Mannose Binding ◽

Defense Molecules

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Development and Validation of a New Scoring Tool to Evaluate the Clinical Evolution of Adult Patients with Nonsegmental Vitiligo

Dermatology ◽

10.1159/000511890 ◽

2021 ◽

pp. 1-9

Author(s):

María Luisa Peralta-Pedrero ◽

Denisse Herrera-Bringas ◽

Karla Samantha Torres-González ◽

Martha Alejandra Morales-Sánchez ◽

Fermín Jurado Santa-Cruz ◽

...

Keyword(s):

Body Surface ◽

Task Force ◽

Intraclass Correlation ◽

The Body ◽

Response To Treatment ◽

Similar Response ◽

Clinical Evolution ◽

Wide Range ◽

Patient Reported ◽

Extreme Groups

Background: Vitiligo has an unpredictable course and a variable response to treatment. Furthermore, the improvement of some vitiligo lesions cannot be considered a guarantee of a similar response to the other lesions. Instruments for patient-reported outcome measures (PROM) can be an alternative to measure complex constructions such as clinical evolution. Objective: The aim of this study was to validate a PROM that allows to measure the clinical evolution of patients with nonsegmental vitiligo in a simple but standardized way that serves to gather information for a better understanding of the disease. Methods: The instrument was created through expert consensus and patient participation. For the validation study, a prospective cohort design was performed. The body surface area affected was measured with the Vitiligo Extension Score (VES), the extension, the stage, and the spread by the evaluation of the Vitiligo European Task Force assessment (VETFa). Reliability was determined with test-retest, construct validity through hypothesis testing, discriminative capacity with extreme groups, and response capacity by comparing initial and final measurements. Results: Eighteen semi-structured interviews and 7 cognitive interviews were conducted, and 4 dermatologists were consulted. The instrument Clinical Evolution-Vitiligo (CV-6) was answered by 119 patients with a minimum of primary schooling. A wide range was observed in the affected body surface; incident and prevalent cases were included. The average time to answer the CV-6 was 3.08 ± 0.58 min. In the test-retest (n = 53), an intraclass correlation coefficient was obtained: 0.896 (95% CI 0.82–0.94; p < 0.001). In extreme groups, the mean score was 2 (2–3) and 5 (4–6); p < 0.001. The initial CV-6 score was different from the final one and the change was verified with VES and VETFa (p < 0.05, n = 92). Conclusions: The CV-6 instrument allows patient collaboration, it is simple and brief, and it makes it easier for the doctor to focus attention on injuries that present changes at the time of medical consultation.

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