Evaluating results of retroperitoneal and transperitoneal laparoscopic living donor nephrectomy in Hue Central Hospital

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Ngọc Khánh Trần ◽  

Abstract Introduction: Laparoscopic living donor nephrectomy (LLDN), which is standard technique, has more advantages than open nephrectomy. Today, there are two approachs in LLDN, including retroperitoneal and transperitoneal. We evaluate results of modified retroperitoneal and transperitoneal laparoscopic living donor nephrectomy, give selection criteria as well as the advantages and disadvantages of each approach. Materials and Methods: Prospective study of 84 voluntary living kidney donors who underwent modified retroperitoneal and transperitoneal laparoscopic living donor nephrectomy (RPLDN) and (TPLDN) in Transplant Center, Hue Central Hospital, between 1/2018 and 6/2020. Results: The difference in BMI among two groups was roughly 2 (Kg/m2) (p<0,05). The perioperative, postoperative complication rate and the conversion rate to open surgery were similar between the two groups. The surgical time and blood loss was significantly lower in RPLDN (139,38 ± 24,73 min, 46,35 ± 13,32 ml) than in TPLDN (174,39 ± 40,86 min, 67,92 ± 30,76 ml) (p<0,05). Comparing characteristics such as warm ischemic time, hospital stays, flatulence time, removal time of drainage and urinary catheter indicated that they were similar between the two groups (p>0,05). Conclusion: Both RPLDN and TPLDN are safe and effective procedures. RPLDN should be conducted in patients with low BMI (< 23 kg/m2), previous abdominal operations and wide flank space. Moreover, modified RPLDN has shorter operative time, less blood loss and good esthetic aspect comparing to TPLDN. Key word: Retroperitoneal laparoscopic, transperitoneal laparoscopic, nephrectomy living donor. Tóm tắt Đặt vấn đề: Phẫu thuật nội soi (PTNS) lấy thận ghép trên người hiến sống được xem là phương pháp có nhiều ưu điểm hơn so với mổ mở kinh điển. Hiện nay, có 2 phương pháp tiếp cận chính là sau phúc mạc (RPLDN) và xuyên phúc mạc (TPLDN). Chúng tôi đánh giá kết quả PTNS sau phúc mạc có cải biên và phẫu thuật xuyên phúc mạc để lấy thận ghép trên người hiến sống, đưa ra các tiêu chuẩn chọn lựa cho mỗi phương pháp và ưu nhược điểm của mỗi phương pháp. Phương pháp nghiên cứu: Nghiên cứu tiến cứu 84 người bệnh (NB) hiến thận tự nguyện được phẫu thuật lấy thận nội soi sau phúc mạc cải biên và xuyên phúc mạc tại Trung tâm Ghép tạng, Bệnh viện Trung ương Huế từ tháng 1/2018 đến tháng 6/2020. Kết quả: Chỉ số BMI có sự khác biệt giữa 2 nhóm RPLDN và TPLDN khoảng 2 (Kg/m2) (p<0,05). Tỷ lệ biến chứng trong mổ, tỷ lệ biến chứng sau mổ là tương đương nhau giữa 2 nhóm. Thời gian phẫu thuật và lượng máu mất của phương pháp nội soi sau phúc mạc là thấp hơn (139,38 ± 24,73 phút, 46,35 ± 13,32 ml) đáng kể so với xuyên phúc mạc (174,39 ± 40,86 phút, 67,92 ± 30,76 ml) (p<0,05). Thời gian thiếu máu nóng, thời gian hậu phẫu, thời gian có trung tiện, thời gian rút ống dẫn lưu, thời gian rút sonde tiểu, nghiên cứu của chúng tôi cũng cho thấy sự tương đồng giữa 2 nhóm (p>0,05). Kết luận: PTNS sau và xuyên phúc mạc là 2 phương pháp an toàn và hiệu quả trong lấy thận ghép trên người hiến sống. Nội soi sau phúc mạc nên áp dụng cho các ca hiến có chỉ số BMI thấp (< 23 kg/m2), khoảng hông lưng rộng hay có phẫu thuật vùng bụng trước đó. PTNS sau phúc mạc cải biên có thời gian phẫu thuật nhanh hơn, ít mất máu hơn nhưng ít thẩm mỹ hơn xuyên phúc mạc. Từ khóa: Nội soi sau phúc mạc, nội soi xuyên phúc mạc, lấy thận người hiến sống.

2018 ◽  
Vol 24 (8) ◽  
pp. 6238-6241
Author(s):  
Karina Evelyn Sidabutar ◽  
A. R Hamid ◽  
Nur Rasyid ◽  
Arry Rodjani ◽  
Irfan Wahyudi ◽  
...  

To assess the reliability and safety of polymer clips for vascular control in laparoscopic living donor nephrectomy. We collected data retrospectively from all laparoscopic living donor nephrectomy performed in Ciptomangunkusumo Hospital, Jakarta, Indonesia. Polymer clips was applied for both renal artery and renal vein ligation. The incidence of polymer clip failure was recorded accordingly. Between November 2011 and August 2015, we evaluated 260 patients of laparoscopic living donor nephrectomy in a center. The left kidney was harvested from 219 (84.5%) patients. Multiple renal arteries was discovered in 25 (9.6%) patients. For all cases we used polymer clips to control the renal artery (XL and L) and renal vein (XL). We placed 2 clips as proximal as possible to the aorta or caval vein. The median estimated blood loss was 100 (20–2000) ml. A blood loss of 2000 ml occurred in one/case of clip dislodgement. The median time to clip (the length of time from first incision to renal artery clamping) was 155 (68–318) minutes. The median warm ischemic time (the length of time from clamping to cold ischemic time) was 3.01 (1.22–30.43) minutes. There were 10 cases with warm ischemic time of more than 10 minutes. Three cases (1.2%) of clip failures occurred. One patient needed conversion to open surgery to achieve adequate vascular control. Two patients experienced improper locking of the polymer clips, necessitating clips reapplication. The use of polymer clips for vascular control in laparoscopic living donor nephrectomy is reliable and safe when properly applied. However the evaluation of renal vascular stump after harvesting donor kidney is an important step to ensure the right placement and safety of polymer clips.


2014 ◽  
Vol 21 (2) ◽  
Author(s):  
Chaidir Arif Mochtar ◽  
Irfan Wahyudi ◽  
Bagus Baskoro

Objective: To evaluate and analyze variables related to the surgical and direct post-operative outcomes of our initial experience of laparoscopic living donor nephrectomies (LLDN). Material & methods: This retrospective analysis describes the first 10 laparoscopic nephrectomies in living donors performed in Cipto Mangunkusumo Hospital. All surgeries were performed by the same surgical team. Variables related to the surgical and post-operative outcome and complications in donors were evaluated and analyzed.Results: The average age of the donors was 31.8 years with male : female ratio of 7 : 3. Thirty percent of them were family related to the recipient. The left kidney was extracted from all patients and multiple renal vessels were found in one cases. The mean operation time was 321.9 ± 27 min, first warm ischemia time was 9.37 ± 3.34 min and estimated blood loss was 270 ± 182.87ml. The hospital stay was 4.1 ± 1.3 days, VAS in the first day post surgery was 3 ± 1 with epidural analgesia needed for 1.8 ± 0.6 days, and drain was kept in for 2.8 ± 1.2 days while urethral cathether for 2.4 ± 1.2. Time to return to work was 16 ± 8.4 days. Conclusion: LLDN results in acceptable blood loss,less post-operative pain, short hospital stay and short time to return to work for the donors, therefore promising to be the gold standard among living donor nephrectomy surgical options.Keywords: Laparoscopic living donor nephrectomy,renal transplantation, Indonesia.


2019 ◽  
Vol 19 (2) ◽  
pp. 44-47
Author(s):  
Ryan Rochon ◽  
Mauricio Monroy ◽  
Serdar Yilmaz

Background:  Rhabdomyolysis is a post-operative complication resulting from skeletal muscle injury during the surgery.  The true incidence of rhabdomyolysis in laparoscopic living donor nephrectomy is unknown due to a paucity of evidence in the literature. Rhabdomyolysis can have serious short-term and long-term consequences for the living kidney donors. There have been a number of risk factors identified that may increase the risk of rhabdomyolysis. Materials and Methods: Our program has offered a hand assisted laparoscopic donor nephrectomy approach for our donors since 2001.We have performed 209 kidney transplants using this approach.  The institution’s database was searched for postoperative complications. Three donor patients with post-operative rhabdomyolysis were identified. Results: All three patients were young healthy males.  The operative times were all greater than four hours.  Fortunately, all three patients were recognized early and received treatment promptly.  Dialysis was not required and no long-term renal dysfunction occurred. Conclusion:  Rhabdomyolysis is an uncommon post-operative complication following hand assisted laparoscopic living donor nephrectomy.  We have a high index of suspicion for rhabdomyolysis to promptly recognize this rare but potentially serious complication after any operation lasting greater than 4 hours.  Creatinine Kinase levels have been implemented at our centre for all living kidney donors. Journal of Surgical Sciences (2015) Vol. 19 (2) : 44-47


Urology ◽  
2007 ◽  
Vol 70 (6) ◽  
pp. 1060-1063 ◽  
Author(s):  
Burak Kocak ◽  
Talia B. Baker ◽  
Alan J. Koffron ◽  
Joseph R. Leventhal

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