Copper ferrite catalyst for direct arylation of acidic C-H bonds in azoles with aryl aldehydes

2021 ◽  
Vol 10 (4) ◽  
pp. 64-68
Author(s):  
Cuong Vu Minh ◽  
Anh Nguyen Thai ◽  
Nam Phan Thanh Son ◽  
Tung Nguyen Thanh
Keyword(s):  
Functional Groups ◽  
Aryl Halides ◽  
Copper Ferrite ◽  
Coupling Reagents ◽  
Direct Arylation ◽  
Aryl Aldehydes ◽  
Benzaldehyde Derivatives

Coupling reagents toward direct arylation of C2-H bonds in aryl azoles are often limited to aryl halides. Herein we report a functionalization of the acidic sp2 C-H bonds in benzothiazoles with benzaldehyde derivatives. Reactions proceeded in the presence of commercially ready CuFe2O4 catalyst. Scope of functional groups included chloro, nitro, cyano, and ester groups.

Carbon-Heteroatom Cross-Coupling via an Electronically Excited Nickel (II) Complex

2019 ◽  
Author(s):  
Randolph Escobar ◽  
Jeffrey Johannes
Keyword(s):  
Energy Transfer ◽  
Functional Groups ◽  
Cross Coupling ◽  
Reductive Elimination ◽  
Aryl Halides ◽  
Coupling Reactions ◽  
General Methodology ◽  
Cross Coupling Reactions ◽  
Electronically Excited ◽  
Energy Transfer Pathway

<div>While carbon-heteroatom cross coupling reactions have been extensively studied, many methods are specific and</div><div>limited to a set of substrates or functional groups. Reported here is a method that allows for C-O, C-N and C-S cross coupling reactions under one general methodology. We propose that an energy transfer pathway, in which an iridium photosensitizer produces an excited nickel (II) complex, is responsible for the key reductive elimination step that couples aryl halides to 1° and 2° alcohols, anilines, thiophenols, carbamates and sulfonamides.</div>

Borates as a Traceless Activation Group for Intermolecular Alkylarylation of Ethylene through Photoredox/Nickel Dual Catalysis

Synlett ◽  
2020 ◽  
Author(s):  
Shengqing Zhu ◽  
Lingling Chu ◽  
Xiaoliang Feng ◽  
Lei Guo
Keyword(s):  
Functional Groups ◽  
Aryl Halides ◽  
Nickel Catalysis ◽  
Mild Conditions ◽  
Dual Catalysis

AbstractA formal ethylene alkylarylation reaction with aryl halides and alkyl oxalates enabled by synergistic photoredox/nickel catalysis is reported. This protocol takes advantage of borates as a traceless activation group, achieving the formal ethylene difunctionalized products via a catalytic three-component 1,2-alkylarylation of vinyl borate followed by a base-assisted deborylation process. The mild conditions allow for excellent functional groups compatibility and broad substrate scope.

Iron-Catalyzed Direct Arylation of Unactivated Arenes with Aryl Halides

2010 ◽  
Vol 49 (11) ◽  
pp. 2004-2008 ◽  
Author(s):  
Wei Liu ◽  
Hao Cao ◽  
Aiwen Lei
Keyword(s):  
Aryl Halides ◽  
Direct Arylation

Styrylsilane coupling reagents for immobilization of organic functional groups on silica and glass surfaces

2018 ◽  
Vol 54 (71) ◽  
pp. 9961-9964 ◽  
Author(s):  
Soo-Bin Kim ◽  
Chang-Hee Lee ◽  
Chul-Ho Jun
Keyword(s):  
Functional Groups ◽  
Coupling Reagents ◽  
Organic Functional Groups ◽  
Glass Surfaces

Styrylsilanes serve as new coupling reagents for introducing organic functional groups on silica and glass surfaces.

scholarly journals Palladium-Catalyzed C12-Selective Direct Arylation of [1,2-c]Quinazolin-6(5H)-ones

Synthesis ◽  
2019 ◽  
Vol 51 (17) ◽  
pp. 3287-3294
Author(s):  
Antonio Arcadi ◽  
Sandro Cacchi ◽  
Giancarlo Fabrizi ◽  
Andrea Fochetti ◽  
Francesca Ghirga ◽  
...  
Keyword(s):  
Aryl Halides ◽  
Direct Arylation ◽  
Palladium Catalyzed ◽  
Straightforward Approach

A straightforward approach to the synthesis of the challenging 12-arylindolo[1,2-c]quinazolin-6(5H)-ones through the palladium-catalyzed direct arylation of N-benzyl and NH-free [1,2-c]quinazolin-6(5H)-ones with aryl halides is described.

Pd-NHC-Catalyzed Direct Arylation of 1,4-Disubstituted 1,2,3-Triazoles with Aryl Halides

2012 ◽  
Vol 30 (4) ◽  
pp. 979-984 ◽  
Author(s):  
Tao He ◽  
Min Wang ◽  
Pinhua Li ◽  
Lei Wang
Keyword(s):  
Aryl Halides ◽  
Direct Arylation

ChemInform Abstract: Palladium-Catalyzed Direct Arylation of Methyl Sulfoxides with Aryl Halides.

ChemInform ◽  
2013 ◽  
Vol 44 (35) ◽  
pp. no-no
Author(s):  
Tiezheng Jia ◽  
Ana Bellomo ◽  
Kawtar EL Baina ◽  
Spencer D. Dreher ◽  
Patrick J. Walsh
Keyword(s):  
Aryl Halides ◽  
Direct Arylation ◽  
Palladium Catalyzed

scholarly journals K2S2O8-Promoted Aryl Thioamides Synthesis from Aryl Aldehydes Using Thiourea as the Sulfur Source

Molecules ◽  
2018 ◽  
Vol 23 (9) ◽  
pp. 2225 ◽  
Author(s):  
Yongjun Bian ◽  
Xingyu Qu ◽  
Yongqiang Chen ◽  
Jun Li ◽  
Leng Liu
Keyword(s):  
Transition Metal ◽  
Functional Groups ◽  
Sulfur Atom ◽  
Coupling Reaction ◽  
Sulfur Source ◽  
Atom Transfer ◽  
Free Condition ◽  
Metal Free ◽  
Aryl Aldehydes ◽  
Three Component Coupling

Thiourea as a sulfur atom transfer reagent was applied for the synthesis of aryl thioamides through a three-component coupling reaction with aryl aldehydes and N,N-dimethylformamide (DMF) or N,N-dimethylacetamide (DMAC). The reaction could tolerate various functional groups and gave moderate to good yields of desired products under the transition-metal-free condition.

Cobalt‐Catalyzed Direct Arylation of Unactivated Arenes with Aryl Halides

2011 ◽  
Vol 17 (13) ◽  
pp. 3588-3592 ◽  
Author(s):  
Wei Liu ◽  
Hao Cao ◽  
Jie Xin ◽  
Liqun Jin ◽  
Aiwen Lei
Keyword(s):  
Aryl Halides ◽  
Direct Arylation
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