scholarly journals Late-Onset GBS Lower Extremity Cellulitis in Premature Neonate with a GBS Negative Mother with Alternative Modes of Transmission: A Case Report

2021 ◽  
Vol 16 (1) ◽  
pp. 29-32
Author(s):  
Bansari Patel ◽  
Lakshan Fonseka ◽  
Nasser Hashem ◽  
Mitchell Goldstein

Purpose: To report a case of cellulitis-causing late-onset Group B streptococcus (GBS) GBS in a neonate with a previously negative antenatal tested mother. This report aims to discuss the various transmission modes potentially causing this case of cellulitis, such as contaminated breast milk.  Case Description:  A preterm neonate, born via cesarean section (C-section) at 29 weeks gestation to a G1P0 mother with a negative GBS rectovaginal antenatal swab test, subsequently developed late-onset cellulitis in the lower extremity due to GBS 19 days later.  Methods: This is a retrospective case report followed by clinical observation, blood cultures, imaging, and antibiotic interventions.    Results: A neonate with left lower extremity cellulitis was found to be GBS positive from a previously negative antenatal GBS-negative mother.   Discussion: As GBS is a common pathogen of neonatal sepsis and less commonly cellulitis, testing rectovaginal fluids once may not be enough to prevent neonates and preterm infants from protecting against transmission. As there have been rare cases of GBS-contaminated breast milk, culturing and testing of breast milk should also be considered, especially in preterm infants.

2016 ◽  
Vol 27 (1) ◽  
pp. 22-28
Author(s):  
Mahima Agrawal

Abstract Complex regional pain syndrome (CRPS) of the lower limb is a relatively uncommon entity as compared to CRPS of the upper extremity. Literature search has revealed only 2 retrospective case series and a single case report of lower extremity CRPS type I from 1975 to 2014 on Pubmed, isolated cases of CRPS type I of lower extremity have also been reported following knee surgeries and arthroscopies. This report presents a case of lower limb CRPS type I following blunt trauma to right foot, treatment of which was directed towards management of allodynia, vasomotor symptoms and surgical correction of deformity which had developed because of the disease, coping mechanisms were also reinforced through counselling and relaxation training. The individual responded well to treatment with a reported 75% reduction in the disabling symptoms and improvement in ambulatory status.


2012 ◽  
Vol 32 (suppl_1) ◽  
Author(s):  
Pooja M Swamy ◽  
Abeer Berry ◽  
Mahir D Elder

BACKGROUND: Complications of the vascular access-site (VAS) are not uncommon. With the evolution of hemostatic techniques used in the access site closure, in the last two decades, the rate of VAS related complications has significantly reduced from 6% to 2%. However, they still remain to be an important cause of morbidity following catheterization procedures. The most common complications encountered with closure of VAS are hematoma formation, arterio-venous fistula, dissection, pseudo -aneurysm and limb ischemia. According to two meta-analyses, the incidences of these complications were very low. The incidence of collagen plug from an Angioseal(™) device causing acute leg ischemia is low and upon occurrence, the use of an Angioscore(™) balloon in successful revascularization has never been reported. CASE PRESENTATION: A 62-year-old male with known severe peripheral artery disease, diabetes mellitus, hypertension and hypercholesterolemia had a successful angioplasty of a 100% chronically occluded right superficial femoral artery (SFA) via the left common femoral artery. An Angioseal (™) closure device was used to achieve hemostasis. The patient was discharged home after an uneventful post procedural course. Two days later, he presented to the ER with a cold and numb left lower extremity. On exam, the left lower extremity had no palpable pulse from below right femoral artery, confirmed by Doppler. The extremity was cold to touch with decreased sensory perception. Patient was found to have critical left lower extremity ischemia. He was emergently taken for a selective left lower extremity angiogram using the right common femoral artery for access. Fragments of the closure device and a collagen plug causing a total occlusion of the left common femoral artery were found. After a pre-dilatation with a 4.0x 40 balloon under prolonged inflations, a lesion reduction from 100 % to 30% with a TIMI 0 to TIMI 3 flow was achieved using an Angioscore (™) 5.0x 40 balloon inflated at 10 atmospheres. Subsequently, using laser 2.0 atherectomy of the left common femoral artery was performed. Flow in the dorsalis pedis artery was confirmed with Doppler. DISCUSSION: The Angio-Seal(™) device has a polylactide and polyglycolide polymer anchor, a collagen plug and a suture contained within a carrier system. Hemostasis is achieved by compressing the arterial puncture site between the anchor and the collagen plug. With newer studies, it appears that the occurrence of critical limb ischemia from collagen plug is under recognized. We therefore, with this case report urge the physicians to be aware of this serious though rare complication of closure devise and also highlight the successful use of Angioscore (™) balloon in the emergent treatment of non-athermatous vascular occlusion causing critical limb ischemia.


2015 ◽  
Vol 9 (1) ◽  
Author(s):  
Natalia Palmou-Fontana ◽  
Enrique Judez Navarro ◽  
Oscar Martín Melero ◽  
Sergio Losa Palacios

2011 ◽  
Vol 37 (1) ◽  
pp. 6 ◽  
Author(s):  
Manuela Chiavarini ◽  
Patrizia Bragetti ◽  
Alessandra Sensini ◽  
Elio Cenci ◽  
Roberto Castronari ◽  
...  

2021 ◽  
Vol 8 (3) ◽  
pp. 1090-1098
Author(s):  
Biljana Otašević ◽  
Bojana Petrović ◽  
Emina Čolak ◽  
Tatjana Nikolić ◽  
Aleksandar Stefanović ◽  
...  

Introduction: Hypocalcemia in preterm infants could occurs as early or late. Causes of late onset of hypocalcaemia: maternal vitamin D deficiency, metabolic syndromes, congenital abnormalities, iatrogenic (transfusion, bicarbonate therapy, phototherapy, antibiotics). Case report: The authors describe the occurrence of late hypocalcemia following transfusion of erythrocytes to the second newborn from a twin pregnancy born prematurely in the 32/33 week of gestation. Mother is diabetic and has hypertension, edema, hypothyroidism, and preeclampsia during pregnancy. Due to the detected pyelectasis in newborn, prophylactic use of cephalexin was introduced. At the end of the first month of life, anemia appear indicating a transfusion. The infant received 50 ml an O+ leukodepleted RBC transfusion. Immediately after transfusion was completed, there is a short-term deterioration of the general condition. Cyanosis, stiffness, trismus, and bradycardia appear within a few seconds. DAT was negative, bilirubin in the reference range. After transfusion, laboratory, echosonographic examination, neurological examination, EEG and ECG showed normal results. It was concluded that the adverse reaction was probably caused by transfusion. Conclusion: In preterm infants, hypocalcaemia may occur during transfusion due to citrate overload. Children of diabetic mothers, on antibiotic and photo therapy are at higher risk of developing hypocalcemia. Future studies should evaluate incidence rate of adverse transfusion reactions in newborns.


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