scholarly journals Kuwait National Mammography Screening Program: outcomes of 5 years of screening in Kuwaiti women

2021 ◽  
Vol 41 (5) ◽  
pp. 257-267
Author(s):  
Hanaa Abdulla Alkhawari ◽  
Akram Mahmoud Asbeutah ◽  
Abdullah Abdulaziz Almajran ◽  
Latifa Abdullah AlKandari
Keyword(s):  
Breast Cancer ◽  
Early Detection ◽  
Mammography Screening ◽  
Ductal Carcinoma ◽  
Screening Program ◽  
Retention Rate ◽  
Lobular Carcinoma ◽  
Participation Rate ◽  
Program Outcomes ◽  
Mammography Screening Program

BACKGROUND: Breast cancer is the most common malignancy among women in Kuwait, representing 39.8% of all female cancer cases. OBJECTIVES: Report the data of the Kuwait National Mammography Screening Program (KNMSP) for a 5-year period. DESIGN: Prospective data collection. SETTING: Population-based screening. SUBJECTS AND METHODS: We included mammography screens done for Kuwaiti women (age 40 years and older) who attended the KNMSP from 2014 to 2019 to screen for breast cancer. A full-field digital mammography system was used to acquire the mammographic images in craniocaudal and mediolateral oblique projections. Independent double-blind reading of the mammograms was performed by two radiologists. MAIN OUTCOME MEASURE: Early detection of breast cancer. SAMPLE SIZE: 14 773 asymptomatic women met inclusion criteria (mean [SD] age, 51.8 (8.2). RESULTS: Lesions were detected in 551 women (3.7%). These included 233 malignant lesions (233/551, 42.3%), 57 high-risk lesions (10.3%) and 261 benign lesions (47.4%). The participation rate was 7.8% of the target population of women 40–69 years of age. The majority of breast cancer cases were reported in the age group 45–49 years (23.2%). The KNMSP study recall rate for 5 consecutive years was in a range of 11.9–16.5% (mean, 14.3%). The detection rate of ductal/lobular carcinoma in situ and invasive breast cancer were 2.5 and 13.6 per 1000 screened women, respectively. Invasive ductal carcinoma was the most common type. Only 4314 women followed up within 12–15 months of the first mammography for a retention rate of 29.2%. CONCLUSIONS: Screening mammography improves early detection of breast cancer in women older than 40 years but poor participation is a limitation. We are aiming to increase the participation rate to 70% of the population. LIMITATIONS: Lack of participation by women. CONFLICT OF INTEREST: None.

Coorscreen: A Low-Cost, on-Site Mammography Screening Program

1996 ◽  
Vol 10 (5) ◽  
pp. 364-370 ◽  
Author(s):  
Mary Greenwood ◽  
Joanne Henritze
Keyword(s):  
Breast Cancer ◽  
Early Detection ◽  
Malignant Disease ◽  
Screening Program ◽  
Low Cost ◽  
Cost Savings ◽  
Participation Rate ◽  
Program Cost ◽  
Mammography Screening Program ◽  
Screening And Prevention

Setting. Coors Brewing Company is a self-insured corporation of 10,600 employees located in Golden, Colorado. Management has long believed in the value of a healthy workforce and has instituted ongoing health and wellness programming since 1981. Program design. Coorscreen was started in September 1985 to create an ongoing awareness of breast cancer screening and prevention for all female employees, spouses, and retirees and to lower the health care costs for the company through early detection of breast cancer. Program impact. From 1985 through 1993, 12,210 mammograms were completed on 3729 employees, spouses, and retirees. The participation rate was 83%. Forty-seven malignant conditions were confirmed during the first 8 years. Pathology reports confirmed 43 early detections (10 employees) and four late detections (two employees). The 10 cases of malignant disease detected early among employees cost an average of $12,388 in terms of direct medical costs, short-term disability, temporary replacement, and ongoing benefits. The two cases detected late among employees cost an average of $143,398. Among spouses, cases of malignant disease detected late have cost an average of $69,230 more than cases detected early. On the basis of early detection for 10 employees and 26 spouses, the total savings are estimated to be $3,110,000. Discussion. The Coorscreen program cost savings for the first 8 years were $3,110,080 because of the lower cost of early versus late detection. Total screening and procedural costs to the company have equaled $668,690. Thus the company has realized a total cost savings of $2,441,190.

scholarly journals Implementation of the German Mammography Screening Program (German MSP) and First Results for Initial Examinations, 2005-2009

Breast Care ◽  
2016 ◽  
Vol 11 (3) ◽  
pp. 183-187 ◽  
Author(s):  
Daniela Malek ◽  
Vanessa Kääb-Sanyal
Keyword(s):  
Mammography Screening ◽  
Ductal Carcinoma ◽  
Screening Program ◽  
Breast Cancer Incidence ◽  
Performance Outcomes ◽  
Long Term Effects ◽  
Screening Process ◽  
Federal States ◽  
Target Values ◽  
Mammography Screening Program

Background: The German Mammography Screening Program (German MSP) is population-based and intended for women aged 50-69 years (approximately 10.5 million). The program started in 2005 and was implemented within 5 years. This article describes the implementation, structure, and screening process, and presents the results of initial examinations for the prevalence phase. Methods: Data were collected annually from invitation centers (invitation, attendance), screening units (performance, outcomes), and cancer registries (incidence). Results: In 2009, 92% of all annually eligible women were invited; 50% of the annually eligible population participated. The total cancer detection rate in the period of 2005-2009 was 8.1/1,000; the corresponding recall rate was 5.9%. 19.6% of detected cancers were ductal carcinoma in situ; 76.7% of invasive cancers were ≤ 20 mm in size, 30.2% were ≤ 10 mm, and 75.3% were node-negative. During the implementation period, incidence increased by 37 and 56% in the old and new federal states, respectively. Incidence rates decreased following the prevalence phase. Conclusion: The German MSP was successfully implemented. The results of the prevalence phase meet the target values of the European guidelines. Proper functioning of the program is also verified by its effects on breast cancer incidence. To draw reliable conclusions regarding the long-term effects of the program, results from the routine screening rounds have to be awaited.

Breast cancer subtype and screening sensitivity in the Quebec Mammography Screening Program

2018 ◽  
Vol 26 (3) ◽  
pp. 154-161
Author(s):  
Linda Perron ◽  
Sue-Ling Chang ◽  
Jean-Marc Daigle ◽  
Nathalie Vandal ◽  
Isabelle Theberge ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Mammography Screening ◽  
Triple Negative ◽  
Screening Program ◽  
Luminal A ◽  
Her2 Positive ◽  
Cancer Subtypes ◽  
Luminal B ◽  
Mammography Screening Program ◽  
Screening Sensitivity

Objective In mammography screening, interval cancers present a problem. The metric ‘screening sensitivity’ monitors both how well a programme detects cancers and avoids interval cancers. To our knowledge, the effect of breast cancer surrogate molecular subtypes on screening sensitivity has never been evaluated. We aimed to measure the 2-year screening sensitivity according to breast cancer subtypes. Methods We studied 734 women with an invasive breast cancer diagnosed between 2003 and 2007 after participating in one regional division of Quebec’s Mammography Screening Program. They represented 83% of all participating women with an invasive BC diagnosis in that region for that period. Tumours were categorized into ‘luminal A-like’, ‘luminal B-like’, ‘triple-negative’ and ‘HER2-positive’ subtypes. We used logistic regression and marginal standardization to estimate screening sensitivity, sensitivity ratios (SR) and sensitivity differences. We also assessed the mediating effect of grade. Results Adjusted 2-year screening sensitivity was 75.4% in luminal A-like, 66.1% in luminal B-like, 52.9% in triple-negative and 45.3% in HER2-positive, translating into sensitivity ratios of 0.88 (95% confidence interval [CI] = 0.78–0.98) for luminal B-like, 0.70 (CI = 0.56–0.88) for triple-negative and 0.60 (CI = 0.39–0.93) for HER2-positive, when compared with luminal A-like. Grade entirely mediated the subtype-sensitivity association for triple negative and mediated it partly for HER2-positive. Screening round (prevalent vs. incident) did not modify results. Conclusion There was substantial variation in screening sensitivity according to breast cancer subtypes. Aggressive phenotypes showed the lowest sensitivity, an effect that was mediated by grade. Tailoring screening according to women’s subtype risk factors might eventually lead to more efficient programs.

scholarly journals Breast cancer screening program in Lithuania: trends in breast cancer mortality before and during the introduction of the mammography screening programme

2020 ◽  
Vol 28 (2) ◽  
pp. 20-28
Author(s):  
Laura Steponavičienė ◽  
Rūta Briedienė ◽  
Rasa Vansevičiūtė-Petkevičienė ◽  
Daiva Gudavičienė ◽  
Ieva Vincerževskienė
Keyword(s):  
Breast Cancer ◽  
Cancer Mortality ◽  
Mammography Screening ◽  
Screening Program ◽  
Breast Cancer Mortality ◽  
Target Population ◽  
Population Based ◽  
Cancer Awareness ◽  
Cancer Screening Program ◽  
Mammography Screening Program

BackgroundBreast cancer is the most frequent oncological disease as well as the leading cause of cancer death among women worldwide. Decline in mortality in economically strong countries is observed. This decline is mostly related to early diagnosis (improvement in breast cancer awareness and mammography screening program (MSP)) and more effective treatment. In the end of 2005, the MSP started in Lithuania. The main aim of this article was to evaluate breast cancer mortality during 22 years in Lithuania, as well as changes before the start of the MSP and during its implementation, in order to assess the influence of the MSP on mortality. Materials and MethodsAnalysis was based on data from the population-based Lithuanian Cancer Registry. Analysis of changes in mortality included the period from 1998 to 2019. Age standardized mortality rates were calculated for assessment of changes. Join-point regression analysis was used. ResultsApplying the segmental regression model, it was found that during the study period mortality was statistically significantly decreasing by -1.1% each year.  Mortality among women under the age of 50 decreased both before and during the implementation of MSP. Mortality in the target population also was already decreasing until the implementation of the program, but since 2006 significant reduction in mortality was observed in this group. ConclusionsOverall breast cancer mortality is decreasing in Lithuania. After the implementation of MSP the largest reduction in mortality was observed among the target population, however, it is not as pronounced as it could be with the well-organized MSP.

Mortality reduction in the Swedish mammography screening program.

2011 ◽  
Vol 29 (27_suppl) ◽  
pp. 29-29
Author(s):  
P. H. Zahl ◽  
J. Mæhlen
Keyword(s):  
Breast Cancer ◽  
Cancer Mortality ◽  
Mammography Screening ◽  
Screening Program ◽  
Breast Cancer Mortality ◽  
Test Group ◽  
Control Group ◽  
Mortality Reduction ◽  
Mammography Screening Program

29 Background: The introduction of a nationwide mammography screening program in Sweden in 1986 was associated with a 50% persistent increase of breast cancer incidence (including carcinoma in situ). Whether screening has been instrumental in a recent decline in the breast cancer mortality remains an open question. Methods: We compared the 18 years breast cancer mortality for two groups of women; those diagnosed in the first 6 years of the screening program and those diagnosed during a 6 year period that included the last 4 years before screening started and the first 2 years of the screening program. The test group (n + 328,927) included women aged 40 to 69 at the first invitation to screening. On average the women in the age-matched control group (n + 317,404) were born 4 years earlier then the women in the test group. The numbers of incident invasive breast cancers in each county were obtained from the Swedish Cancer Registry (in-situ cancers were excluded) and the corresponding breast cancer deaths were obtained from the Swedish Causes of Death Registry. Results: After 18 years follow up, the mortality reduction was 14% in the test group. However, most of this difference (10%) occurred in the first five years after diagnosis reflecting improved medical treatment of breast cancer. Most of the 14% difference also disappeared if we adjusting for period effects. Conclusions: About 83% of women in the test group were also included in the control group making the two groups almost identical with respect to risk variables. By screening the control group at the end of a 6-year period, the results are adjusted for differences due to lead-time bias and by studying mortality instead of survival overdiagnosis (length time bias) is also adjusted for. We conclude that organized mammography screening is not an important cause for the reduction in the breast cancer mortality in Sweden.

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