EFFECT OF TETRAHYDROCURCUMIN ON LIPID PROFILES IN STREPTOZOTOCIN–NICOTINAMIDE INDUCED TYPE 2 DIABETES MELLITUS
Keyword(s):
Hyperlipidemia is one of the major risk factors of cardiovascular complication in diabetes. A study was undertaken to evaluate the antihyperlipidemic activity of tetrahydrocurcumin (THC). Oral administration of THC (80mg/ kg bodyweight) to streptozotocin-nicotinamide induced diabetic rats for 45 days, significantly reduced the elevated serum very low density lipoprotein (VLDL) and low density lipoprotein (LDL) – cholesterol levels and significantly increased the serum high-density lipoprotein (HDL)-cholesterol. THC showed a better effect when compared with curcumin. Results of the present study indicate that THC showed antihyperlipidemic effect in addition to its antidiabetic effect in type 2 diabetic rats
2008 ◽
Vol 23
(1)
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pp. 22
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2010 ◽
Vol 2
(01)
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pp. 025-030
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Keyword(s):
2004 ◽
Vol 62
(2a)
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pp. 233-236
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2016 ◽
Vol 111
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pp. 66-73
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2005 ◽
Vol 19
(5)
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pp. 269-275
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