scholarly journals Pharmaceutical organic salt: Disordered crystal structure of levofloxacin with γ-resorcylic acid

2021 ◽  
Vol 12 (3) ◽  
pp. 323-328
Author(s):  
Syed Muddassir Ali Mashhadi ◽  
Muhammad Nawaz Tahir ◽  
David Apperley ◽  
Moazzam Hussain Bhatti ◽  
Muhammad Ashfaq ◽  
...  
Keyword(s):  
Preparation Method ◽  
Crystal Packing ◽  
Weak Interactions ◽  
Xrd Analysis ◽  
Organic Salt ◽  
Antibacterial Drug ◽  
Triclinic Space Group ◽  
Simple Preparation ◽  
Type C ◽  
Disordered Crystal

This study reports an organic salt prepared from an antibacterial drug, levofloxacin and antioxidant γ-resorcylic acid. A simple preparation method leads to a crystal with disordered structure. The idea is to prepare an organic salt comprising of pharmaceutically acceptable acidic and basic components. The salt is characterised by IR, solid state NMR, and single crystal XRD. Crystal data for C25H26N3O8F: triclinic, space group P-1 (no. 2), a = 7.0037(8) Å, b = 12.764(3) Å, c = 13.909(3) Å, α = 104.821(4)°, β = 92.039(4)°, γ = 95.334(4)°, V = 1194.6(4) Å3, Z = 2, T = 296(2) K, μ(MoKα) = 0.113 mm-1, Dcalc = 1.433 g/cm3, 16879 reflections measured (5.048° ≤ 2Θ ≤ 54.186°), 5139 unique (Rint = 0.0663, Rsigma = 0.0975) which were used in all calculations. The final R1 was 0.1121 (I>2σ(I)) and wR2 was 0.2505 (all data). SC-XRD analysis shows that the crystal packing is stabilized by strong H-bonding of type N-H···O and comparatively weak interactions of type C-H···O, C-H···π and off-set π···π stacking.

scholarly journals 3-(1-Adamantyl)-6-methyl-3-(3-methylbenzyl)isochroman-1-one

2009 ◽  
Vol 65 (6) ◽  
pp. o1190-o1190 ◽  
Author(s):  
Eva Babjaková ◽  
Marek Nečas ◽  
Robert Vícha
Keyword(s):  
Crystal Packing ◽  
Weak Interactions ◽  
Boat Conformation ◽  
Stacking Interactions ◽  
Torsion Angles ◽  
Compound C ◽  
Centroid Distance ◽  
Benzene Rings ◽  
Type C ◽  
Puckering Parameters

In the title compound, C28H32O2, the oxanone ring adopts distorted half-boat conformation with the following Cremer and Pople puckering parameters:Q= 0.619 (2) Å,θ= 0.75 (19) andφ= 172 (13)°. The dihedral angle betwen two benzene rings is 21.32 (7)°. The adamantane unit consists of three fused cyclohexane rings in classical chair conformations, with absolute values of C—C—C—C torsion angles in the range 57.5 (2)–60.9 (2)°. Weak interactions of the type C—H...O link molecules of each enantiomer into chains parallel to thebaxis and lying about inversion centers. The crystal packing is also stabilized by intermolecular π-π stacking interactions [centroid–centroid distance of 3.8566 (11) Å].

Scanning electron microscopy of human iliac bone by a simple preparation method

1990 ◽  
Vol 48 (3) ◽  
pp. 226-227
Author(s):  
Toshihiko Takita ◽  
Tomonori Naguro ◽  
Toshio Kameie ◽  
Akihiro Iino ◽  
Kichizo Yamamoto
Keyword(s):  
Electron Microscopy ◽  
Scanning Electron Microscopy ◽  
Preparation Method ◽  
Specimen Preparation ◽  
Real Surface ◽  
Public Attention ◽  
Preparation Methods ◽  
The Real ◽  
Simple Preparation ◽  
Scanning Electron

Recently with the increase in advanced age population, the osteoporosis becomes the object of public attention in the field of orthopedics. The surface topography of the bone by scanning electron microscopy (SEM) is one of the most useful means to study the bone metabolism, that is considered to make clear the mechanism of the osteoporosis. Until today many specimen preparation methods for SEM have been reported. They are roughly classified into two; the anorganic preparation and the simple preparation. The former is suitable for observing mineralization, but has the demerit that the real surface of the bone can not be observed and, moreover, the samples prepared by this method are extremely fragile especially in the case of osteoporosis. On the other hand, the latter has the merit that the real information of the bone surface can be obtained, though it is difficult to recognize the functional situation of the bone.

Three-dimensionally ordered mesoporous multicomponent (Ni, Mo) metal oxide/N-doped carbon composite with superior Li-ion storage performance

Nanoscale ◽  
2018 ◽  
Vol 10 (39) ◽  
pp. 18734-18741 ◽  
Author(s):  
Se Hwan Oh ◽  
Jin Koo Kim ◽  
Yun Chan Kang ◽  
Jung Sang Cho
Keyword(s):  
Metal Oxides ◽  
Preparation Method ◽  
Carbon Composite ◽  
Pyrolysis Process ◽  
Storage Performance ◽  
Simple Preparation ◽  
Ordered Mesoporous ◽  
Ion Storage ◽  
Li Ion ◽  
Spray Pyrolysis Process

A simple preparation method of mesoporous multicomponent metal oxides containing Ni and Mo components with N-doped carbon by spray pyrolysis process is introduced.

The role of weak interactions in the crystal packing of two novel 1D Hg(II) coordination polymers and investigation for preparation of their rod and spherical structures

2020 ◽  
Vol 501 ◽  
pp. 119243 ◽  
Author(s):  
Ghodrat Mahmoudi ◽  
Payam Hayati ◽  
Khosro Mohammadi ◽  
Ardavan Masoudiasl ◽  
Joel T. Mague ◽  
...  
Keyword(s):  
Coordination Polymers ◽  
Crystal Packing ◽  
Weak Interactions ◽  
Spherical Structures

A simple preparation method for superhydrophobic surface on silicon rubber and its properties

2020 ◽  
Vol 143 ◽  
pp. 105612 ◽  
Author(s):  
Xinyu Zhou ◽  
Guangfei Wang ◽  
Meimei Wang ◽  
Yu Zhang ◽  
Wanlei Yin ◽  
...  
Keyword(s):  
Superhydrophobic Surface ◽  
Preparation Method ◽  
Silicon Rubber ◽  
Simple Preparation

ChemInform Abstract: SIMPLE PREPARATION METHOD FOR O,O-DIGLYCIDYL ALKYL(ARYL)PHOSPHONATES

1985 ◽  
Vol 16 (16) ◽  
Author(s):  
E. V. BAYANDINA ◽  
D. N. SADKOVA ◽  
N. I. RIZPOLOZHENSKII ◽  
I. A. NURETDINOV
Keyword(s):  
Preparation Method ◽  
Alkyl Aryl ◽  
Simple Preparation

Updates on the use of liposomes for active tumor targeting in cancer therapy

Nanomedicine ◽  
2020 ◽  
Vol 15 (3) ◽  
pp. 303-318 ◽  
Author(s):  
Wei Yan ◽  
Sharon SY Leung ◽  
Kenneth KW To
Keyword(s):  
Preparation Method ◽  
Cancer Therapeutics ◽  
Active Targeting ◽  
Anticancer Drug Delivery ◽  
Liposomal Formulations ◽  
Simple Preparation ◽  
Low Toxicity ◽  
Future Direction ◽  
New Anticancer Drugs ◽  
Insight Into

In the development of cancer chemotherapy, besides the discovery of new anticancer drugs, a variety of nanocarrier systems for the delivery of previously developed and new chemotherapeutic drugs have currently been explored. Liposome is one of the most studied nanocarrier systems because of its biodegradability, simple preparation method, high efficacy and low toxicity. To make the best use of this vehicle, a number of multifunctionalized liposomal formulations have been investigated. The objective of this review is to summarize the current development of novel active targeting liposomal formulations, and to give insight into the challenges and future direction of the field. The recent studies in active targeting liposomes suggest the great potential of precise targeted anticancer drug delivery in cancer therapeutics.

scholarly journals Simple preparation method of asphalt polyurethane foam for various insulating purposes

2020 ◽  
Vol 29 (4) ◽  
pp. 257-264
Author(s):  
Z.L. Abo-Shanab ◽  
A.A. Ragab ◽  
M. Mohammedy ◽  
S.A. EI-kholy
Keyword(s):  
Polyurethane Foam ◽  
Preparation Method ◽  
Simple Preparation
Sign in / Sign up

Export Citation Format

Share Document