scholarly journals Effects of Transferrin (TF) Polymorphism on the Levels of Some Blood Serum Indices in Clinically Healthy Piglets and Piglets with Diarrhoea Caused by <i>Escherichia coli</i>

2006 ◽  
Vol 49 (5) ◽  
pp. 484-493
Author(s):  
G. M. Życzko ◽  
K. Życzko ◽  
J. Osek
Keyword(s):  
Blood Serum ◽  
Binding Capacity ◽  
Iron Concentration ◽  
Total Iron ◽  
Total Iron Binding Capacity ◽  
E Coli ◽  
Iron Saturation ◽  
Suckling Piglets ◽  
Iron Binding Capacity ◽  
Made In

Abstract. The effect of transferrin (TF) polymorphism and the levels of some blood serum indices, functionally linked to this protein, were studied. The following determinations were made in the blood serum of 311 hybrid suckling piglets - TF polymorphism, TIBC (total iron binding capacity), TF iron saturation percentage and levels of iron ceruloplasmin (CP) and copper. Clinically healthy piglets and piglets with diarrhoea caused by E. coli were divided into younger (aged 10 to 14 days) and older (aged 15 to 28 days). The piglets showed two genotypes, TF AB and TF BB. The TF BB genotype dominated among clinically healthy piglets, and the TF AB genotype in those suffering from diarrhoea. TF polymorphism differentiated the levels of CP and copper in clinically healthy piglets, and modified iron concentration and TF iron saturation percentage in piglets with diarrhoea. Regardless of health status, age had an almost identical effect on the levels of blood serum indices in piglets of both genotypes. The differences in the levels of CP, iron, and TF iron saturation percentage in healthy piglets and piglets with diarrhoea were modified by the presence of the TFA allele, but in older piglets only.

Clinico-pathological studies on naturally-occurring bovine fascioliasis in the Sudan

1975 ◽  
Vol 49 (3) ◽  
pp. 143-152 ◽  
Author(s):  
E. M. Haroun ◽  
M. F. Hussein
Keyword(s):  
Serum Iron ◽  
Binding Capacity ◽  
Iron Concentration ◽  
Total Iron ◽  
The Other ◽  
Liver Pathology ◽  
Total Iron Binding Capacity ◽  
Iron Saturation ◽  
Naturally Occurring ◽  
Iron Binding Capacity

AbstractAn investigation was made of the pathological, haematological and biochemical aspects of naturallyoccurring bovine fascioliasis in the Sudan. 228 animals infected with Fasdola gigantica and 25 non-infected controls were used in the study.The infected cattle revealed emaciation, typical liver pathology, and, occasionally, lesions in the lung and the pancreas. Analysis of their sera also showed reduced albumin values, increased globulin concentrations and decreased albumin/globulin ratio, in addition to increased arginase activity. The serum iron concentration, on the other hand, was decreased, while the total iron binding capacity increased and the resultant iron saturation values reduced. Haematological findings in the infected animals included reduced erythrocyte counts, decreased haematocrjt values, increased mean corpuscular volumes, eosinophilia and decreased neutrophil, lymphocyte and monocytc counts.

scholarly journals THE MAIN PARAMETERS OF IRON METABOLISM IN PATIENTS WITH UROTELIAL BLADDER CANCER AT DIFFERENT DEVELOPMENT STAGES OF MALIGNANT NEOPLASM ANEMIA

10.23856/4332 ◽  
2021 ◽  
Vol 43 (6) ◽  
pp. 247-255
Author(s):  
Dmytro Borysenko ◽  
Stanislav Vydyborets
Keyword(s):  
Bladder Cancer ◽  
Blood Serum ◽  
Binding Capacity ◽  
Malignant Neoplasm ◽  
Total Iron ◽  
The Body ◽  
Malignant Neoplasms ◽  
Iron Binding ◽  
Total Iron Binding Capacity ◽  
Iron Binding Capacity

The article presents information about the protein responsible for the iron depot in the body – ferritin. Its physiological role and clinical significance are demonstrated. A batophenanthroline method was used to determine the range of iron in the blood serum and the range of the total iron-binding capacity of the blood serum. The range of unsaturated iron-binding capacity of blood serum was calculated as the difference between total iron-binding capacity in blood serum and the range of iron in blood serum. The transferrin saturation coefficient of iron was defined as the ratio of the content of iron in blood serum to the total iron-binding capacity in blood serum. The range of transferrin was determined by the rate of the total iron-binding capacity in blood serum, and ferritin using the radiometric method. The dynamics of changes in ferritin content in malignant neoplasm anemia in patients with bladder cancer has been demonstrated. The conclusion about the importance of this parameter for laboratory diagnosis of iron deficiency and anemia of malignant neoplasms is made.

scholarly journals Dynamics of changes in iron concentration and total iron binding capacity in blood plasma of goat kids during their first month of life (Short Communication)

2009 ◽  
Vol 52 (4) ◽  
pp. 419-424
Author(s):  
W. F. Skrzypczak ◽  
M. Ożgo ◽  
A. Lepczyński ◽  
A. Łata
Keyword(s):  
Blood Plasma ◽  
Binding Capacity ◽  
Iron Concentration ◽  
Total Iron ◽  
Postnatal Life ◽  
Iron Binding ◽  
Total Iron Binding Capacity ◽  
Plasma Iron ◽  
Iron Binding Capacity ◽  
In Blood Plasma

Abstract. The experiment was carried out on 14 kids of Polish Improved White breed during the first 30 days of life. The aim of this study was to show changes in the concentration of blood plasma iron and total iron binding capacity (TIBC) during the neonatal period. The statistically confirmed differences (P≥0.01) in blood serum iron concentration was show in the kids between 5th (20.57 μmol/l) and 14th (9.97 μmol/l) day of life, and between 3rd and 4th week with the peak in 23rd day (27.50 μmol/l). We have also shown statisticly confirmed increase in TIBC (P≥0.01) between 1st and 4th day of life (+20.13 μmol/l), and between 14th and 23rd day of life (+15.59 μmol/l). Statistically confirmed decrease of TIBC was observed between 6th (52.30 μmol/l) and 14th (31.78 μmol/l) day of life. Conclusion: The studies have revealed dynamic changes in the concentration and total binding capacity of blood plasma iron concentration during the first month of postnatal life. The pattern of such changes does not depend on the gender or litter size. It was observed a significant decrease in the concentration of this trace element in blood plasma toward the end of the second week, which may indicate a relative iron deficiency, particularly in twin-born kids.

Day-to-day variation in serum ferritin concentration in healthy subjects.

1981 ◽  
Vol 27 (1) ◽  
pp. 78-82 ◽  
Author(s):  
V A Pilon ◽  
P J Howanitz ◽  
J H Howanitz ◽  
N Domres
Keyword(s):  
Serum Ferritin ◽  
Healthy Subjects ◽  
Serum Iron ◽  
Binding Capacity ◽  
Total Iron ◽  
Iron Binding ◽  
Total Iron Binding Capacity ◽  
Ferritin Concentration ◽  
Iron Saturation ◽  
Iron Binding Capacity

Abstract We report our observations on day-to-day variation in serum ferritin, serum iron, total iron-binding capacity, and percent saturation of binding proteins with iron in 13 ostensibly healthy subjects during five weeks. The average intrasubject coefficients of variation were 14.5, 28.5, 4.8, and 28.0%, respectively. Precision studies on control samples showed greater within-assay and between-assay analytical variation for serum ferritin than for serum iron or total iron-binding capacity. Evidently, serum ferritin varies less in a given individual from day to day than do serum iron and percent iron saturation. Thus, a single measurement of serum ferritin may be a more reliable index of iron stores than an isolated determination of either serum iron or percent iron saturation.

Sign in / Sign up

Export Citation Format

Share Document