scholarly journals EVALUATION OF THE LONG-TERM EFFECTS OF EXPOSURE TO GREENSPACE ON TYPE 2 DIABETIC PATIENTS: CASE STUDY – TEHRAN, IRAN

Author(s):  
A. Esmaeilzadeh ◽  
M. R. Delavar ◽  
E. Nasli-Esfahani

<p><strong>Abstract.</strong> Development of information technology and expansion of geospatial information systems have realized the planning managers and urban policy-makers’ wishes in making more informed decisions about urban management. At the same time, population growth and the provision of its health should be considered as one of the most important and remarkable issues for many researchers and medical specialists. So, in recent years there have been an increasing number of researches related to the study of effective factors such as environment parameters on the people’s health. In previous research, the long-term exposure effects of environmental parameters such as greenspace and air pollution on people’s health have been mostly ignored or access to reliable data has not been accomplished. The aim of this research is to study how the long-term exposure to greenspace surrounding the type 2 diabetes mellitus (T2DM) affects the average values of four years glycolized hemoglobin (HbA1c) levels. Moreover, in order to study the effects of the data type on reliability of the results, land-use data base (LDB) and satellite imagery have been employed. Pearson product and regression model have been used in this research for correlation and buffer analyse to calculate the degree of exposure of T2DM persons to greenspace. According to the results, negative correlation between long-term exposure to greenspace and the average values of four years HbA1c levels becomes statistically significant. Pearson correlation coefficients for the LDB (r&amp;thinsp;=&amp;thinsp;&amp;minus;0.366, p&amp;thinsp;=&amp;thinsp;0.001) and satellite imagery (r&amp;thinsp;=&amp;thinsp;&amp;minus;0.276, p&amp;thinsp;=&amp;thinsp;0.006) at 250-meter buffer from diabetic patients’ habitat is significant at 99% confidence level.</p>

2012 ◽  
Vol 78 (08) ◽  
pp. 122-128 ◽  
Author(s):  
Tiziana Ciarambino ◽  
Pietro Castellino ◽  
Giuseppe Paolisso ◽  
Ludovico Coppola ◽  
Nicola Ferrara ◽  
...  

Diabetes Care ◽  
2007 ◽  
Vol 30 (4) ◽  
pp. 1002-1004 ◽  
Author(s):  
S. Camastra ◽  
M. Manco ◽  
A. Mari ◽  
A. V. Greco ◽  
S. Frascerra ◽  
...  

PeerJ ◽  
2017 ◽  
Vol 5 ◽  
pp. e3405 ◽  
Author(s):  
Lubin Xu ◽  
Yang Li ◽  
Jiaxin Lang ◽  
Peng Xia ◽  
Xinyu Zhao ◽  
...  

Aim To evaluate the effects of sodium-glucose co-transporter 2 (SGLT2) inhibition on renal function and albuminuria in patients with type 2 diabetes. Methods We conducted systematic searches of PubMed, Embase and Cochrane Central Register of Controlled Trials up to June 2016 and included randomized controlled trials of SGLT2 inhibitors in adult type 2 diabetic patients reporting estimated glomerular filtration rate (eGFR) and/or urine albumin/creatinine ratio (ACR) changes. Data were synthesized using the random-effects model. Results Forty-seven studies with 22,843 participants were included. SGLT2 inhibition was not associated with a significant change in eGFR in general (weighted mean difference (WMD), −0.33 ml/min per 1.73 m2, 95% CI [−0.90 to 0.23]) or in patients with chronic kidney disease (CKD) (WMD −0.78 ml/min per 1.73 m2, 95% CI [−2.52 to 0.97]). SGLT2 inhibition was associated with eGFR reduction in short-term trials (WMD −0.98 ml/min per 1.73 m2, 95% CI [−1.42 to −0.54]), and with eGFR preservation in long-term trials (WMD 2.01 ml/min per 1.73 m2, 95% CI [0.86 to 3.16]). Urine ACR reduction after SGLT2 inhibition was not statistically significant in type 2 diabetic patients in general (WMD −7.24 mg/g, 95% CI [−15.54 to 1.06]), but was significant in patients with CKD (WMD −107.35 mg/g, 95% CI [−192.53 to −22.18]). Conclusions SGLT2 inhibition was not associated with significant changes in eGFR in patients with type 2 diabetes, likely resulting from a mixture of an initial reduction of eGFR and long-term renal function preservation. SGLT2 inhibition was associated with statistically significant albuminuria reduction in type 2 diabetic patients with CKD.


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