The Efficacy of Platelet-rich Plasma Combined with Platelet-rich Fibrin in the Treatment of Multiple Chronic Venous Leg Ulcer: A Case Report

Platelets release several growth factors which stimulate tissue regeneration. Several techniques for platelet concentrates such as platelet rich plasma (PRP), plasma rich in growth factors (PRGF), platelet rich fibrin (PRF) and concentrated growth factors (CGF) have been introduced in dental surgeries for the prevention of hemorrhage and acceleration of tissue regeneration. However, a fabricating growth factors-enriched bone graft matrix which is called “sticky bone” has been demonstrated to provide stabilization in bony defects. In this article, we presented the method of preparing and utilizing CGF and sticky bone and evaluate the effect of CGF mixed with bone graft and CGF barrier membrane in periodontal surgeries.Methodology: We used websites such as PubMed, Scopus, and ISI Web of knowledge to get related articles about this subject. The research process involved specific key words " concentrated growth factor”- “Platelet rich fibrin”- growth factors-enriched bone graft” - “sticky bone” to find more articles which published from 2007 to March 2018.Results: We reviewed 48 articles, 43 articles were excluded. Only five articles have been conducted. Original human studies and case report were included.Conclusion: We concluded that the use of sticky bone and CGF is effective in bone grafting and implant.

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Combination treatment with light emitting diode and wound dressings in a patient with a venous leg ulcer: a case report

Acta Dermatovenerologica Alpina Pannonica et Adriatica ◽

10.15570/actaapa.2020.9 ◽

2020 ◽

Vol 29 (1) ◽

Author(s):

Irma Bernadette S. Sitohang ◽

Mutiara Ramadhiani ◽

Karin Rachmani ◽

Hanif Sri Utami ◽

Melani Marissa

Keyword(s):

Case Report ◽

Combination Treatment ◽

Light Emitting Diode ◽

Leg Ulcer ◽

Wound Dressings ◽

Venous Leg Ulcer ◽

Light Emitting

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Venous Leg Ulcer in a Sarcoidosis Patient: A Case Report

Annals of Dermatology ◽

10.5021/ad.2015.27.6.744 ◽

2015 ◽

Vol 27 (6) ◽

pp. 744 ◽

Cited By ~ 1

Author(s):

Jungyoon Ohn ◽

Sang Young Byun ◽

In Su Kim ◽

Kyoung Chan Park

Keyword(s):

Case Report ◽

Leg Ulcer ◽

Sarcoidosis Patient ◽

Venous Leg Ulcer

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Successful treatment of venous leg ulcer with platelet-rich fibrin

Bőrgyógyászati és Venerológiai Szemle ◽

10.7188/bvsz.2020.96.6.1 ◽

2020 ◽

Vol 96 (6) ◽

pp. 303-306

Author(s):

Róbert Kui ◽

◽

Judit Vasas ◽

Győző Szolnoki ◽

Lajos Kemény

Keyword(s):

Successful Treatment ◽

Low Cost ◽

Autologous Blood ◽

Leg Ulcer ◽

Antimicrobial Proteins ◽

Venous Leg Ulcer ◽

Platelet Rich Fibrin ◽

Activated Platelets ◽

Autologous Platelet ◽

Detailed Presentation

The autologous platelet-rich blood derivatives have been used in bioregenerative medicine for decades in various indications including the facilitation of wound healing. Leukocyte- and platelet-rich fibrin (PRF) is a second-generation autologous blood-derived product, which can be obtained relatively easily and at low cost. PRF is rich in growth factors and antimicrobial proteins that are released by activated platelets and leukocytes. The authors present a successful treatment of a venous leg ulcer providing a detailed presentation of the PRF method.

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Management of Chronic Venous Leg Ulcer (traumatic) – A Case Report

Journal of Ayurveda and Integrated Medical Sciences (JAIMS) ◽

10.21760/jaims.v1i4.6935 ◽

2017 ◽

Vol 1 (4) ◽

Author(s):

Oorvi Kulkarni ◽

Prashanth A. S.

Keyword(s):

Deep Vein Thrombosis ◽

Case Report ◽

Leg Ulcer ◽

Chronic Ulcer ◽

Leg Ulcers ◽

Venous Leg Ulcer ◽

Venous Leg Ulcers ◽

Vein Thrombosis ◽

Deep Vein ◽

Guide Lines

A chronic venous leg ulcer is not so common in Ayurvedic practices. But deep vein thrombosis is more common in clinics. Venous and arterial diseases are most usual cause of leg ulcers accounting to 60 to 80% of them. On an average 33 to 60% of these ulcers are present for more than 6 weeks and therefore referred to as venous leg ulcers. The case reported here was as a result of repeated trauma with a history since 20 years. The treatment was given at IPD level diagnosing it as Upadrava Roopi Vatarakta with valid Chikitsa Siddhanta. This case report provides us a guide lines that even a chronic ulcer can be healed with proper assessment of Dosha, Dhatu, Strotas involvement.

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Complete healing and short-term treatment by Argania honey dressing in a venous leg ulcer: case report

Current Traditional Medicine ◽

10.2174/2215083807666210913105216 ◽

2021 ◽

Vol 07 ◽

Author(s):

Leila Khattabi ◽

Kawtar Raghay ◽

Mohamed Dakkach ◽

Mohamed Allouch

Keyword(s):

Case Report ◽

Bacterial Infections ◽

Healing Process ◽

Good Alternative ◽

Complete Healing ◽

Leg Ulcer ◽

Venous Leg Ulcer ◽

Short Term Treatment ◽

Biologic Treatment ◽

Ulcer Case

Background: Recent advances in care aware that inadequate management of the healing process in wounds and the development of bacterial infections leads to increase morbidity. Health professionals have progressively recognized the value of choosing suitable dressings to manage wounds particularly in developing countries. Honey has been used for thousands of years as a wound dressing and considered as biologic treatment due to its multiple bioactivities related to healing process. Objective: The aim of this case report is to demonstrate that Argania Honey dressing improve the healing process in a venous leg ulcer. Method: Pure raw Argania honey (Argania spinosa, endemic tree in southwestern of Morocco) with no additives, pasteurization, or manipulation was used and provided from local beekeepers. A mechanical debridement process was achieved previously to the application of honey dressings to a venous leg ulcer of a 67-year-old woman affected by type II diabetes for 11 years. Results : The Argania honey dressing accompanied by mechanical debridement process demonstrated a rapid recovery and complete healing of the wound for 12 weeks approximately (79 days). Conclusion: This Moroccan honey (Argania) experienced for the first time in venous leg ulcer management may represent a good alternative to treat other types of wounds. Further investigations by using Argania honey dressing are required to explain its effect and the mechanisms involved in the improvement of healing process.

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