Complete healing and short-term treatment by Argania honey dressing in a venous leg ulcer: case report

2021 ◽  
Vol 07 ◽  
Author(s):  
Leila Khattabi ◽  
Kawtar Raghay ◽  
Mohamed Dakkach ◽  
Mohamed Allouch

Background: Recent advances in care aware that inadequate management of the healing process in wounds and the development of bacterial infections leads to increase morbidity. Health professionals have progressively recognized the value of choosing suitable dressings to manage wounds particularly in developing countries. Honey has been used for thousands of years as a wound dressing and considered as biologic treatment due to its multiple bioactivities related to healing process. Objective: The aim of this case report is to demonstrate that Argania Honey dressing improve the healing process in a venous leg ulcer. Method: Pure raw Argania honey (Argania spinosa, endemic tree in southwestern of Morocco) with no additives, pasteurization, or manipulation was used and provided from local beekeepers. A mechanical debridement process was achieved previously to the application of honey dressings to a venous leg ulcer of a 67-year-old woman affected by type II diabetes for 11 years. Results : The Argania honey dressing accompanied by mechanical debridement process demonstrated a rapid recovery and complete healing of the wound for 12 weeks approximately (79 days). Conclusion: This Moroccan honey (Argania) experienced for the first time in venous leg ulcer management may represent a good alternative to treat other types of wounds. Further investigations by using Argania honey dressing are required to explain its effect and the mechanisms involved in the improvement of healing process.

Author(s):  
Irma Bernadette S. Sitohang ◽  
Mutiara Ramadhiani ◽  
Karin Rachmani ◽  
Hanif Sri Utami ◽  
Melani Marissa

2021 ◽  
Vol Volume 14 ◽  
pp. 809-814
Author(s):  
Eva Krishna Sutedja ◽  
Retno Hesty Maharani ◽  
Unwati Sugiri ◽  
Pati Aji Achdiat

2019 ◽  
Vol 35 (4) ◽  
pp. 237-246
Author(s):  
Leon Jonker ◽  
Jane Todhunter ◽  
Jose Schutter ◽  
Charlotte Halliday ◽  
Stacey Fisher

Objectives To evaluate the feasibility of an interventional study involving a seated plantar resistance exercise programme, using a StepIt pedal, aimed at promotion of venous leg ulcer healing. Methods Thirty-two venous leg ulcer patients, recruited from community, GP and hospital settings, were randomised to either a standard care or adjuvant StepIt exercise programme arm for up to 12 weeks. The exercise involved a twice daily routine of 10 times 1 min of exercise, i.e. 2 s push and 2 s lift repetitions (equating to 300 daily ‘steps’). Results Complete healing of the venous leg ulcers was observed in 10 out of 15 (67%; StepIt cohort) and 7 out of 17 (41%; control cohort), respectively (p-value 0.18, Fisher’s exact test). Baseline differences between the two cohorts were longer wound chronicity, less venous leg ulcer-related pain and better venous leg ulcer-related quality of life in the StepIt cohort. One adverse event, involving increased wound exudate and slough production, was observed in a participant using StepIt, and no study withdrawals were recorded in either arm. StepIt users whose wound had completely healed by week 12 were more likely to be compliant with the exercise programme (self-reported) and more positive about the trial experience; however, all would recommend the device to others. Conclusions Seated plantar resistance exercise shows promise and may accelerate venous leg ulcer wound healing. The StepIt pedal is well-received by patients, and its efficacy may depend on the degree of patient compliance with the exercise programme. Further larger scale studies are indicated to allow more concrete inferences to be made on the clinical and potential health economics impact that this device may have.


2015 ◽  
Vol 27 (6) ◽  
pp. 744 ◽  
Author(s):  
Jungyoon Ohn ◽  
Sang Young Byun ◽  
In Su Kim ◽  
Kyoung Chan Park

2019 ◽  
Vol 34 (9) ◽  
pp. 611-620 ◽  
Author(s):  
Jean L Gillet ◽  
Jean J Guex ◽  
François A Allaert ◽  
Bernard Avouac ◽  
Philippe Leger ◽  
...  

Objective To evaluate the efficacy, safety and acceptability of an innovative two-component versus a well-established four-component compression systems in the management of venous leg ulcer. Method Multicentre randomized controlled trial in patients with active venous leg ulcer. Patients were followed-up monthly for a maximum of 16 weeks. The primary endpoint was the complete healing rate at 16 weeks. Results Ninety-two patients were randomized to either the two-component BIFLEX® Kit group ( n = 49) or the four-component PROFORE® group ( n = 43). In the full analysis set ( n = 88), a complete healing rate of 48.9% and 24.4% was reported in BIFLEX® Kit versus PROFORE® groups, respectively (i.e. a superiority of 24.5%, p = 0.02). Acceptability of BIFLEX® Kit was higher from both the patients’ and physicians’ perspectives. Conclusion The BIFLEX® Kit represents a valid alternative therapy in the management of venous leg ulcer according to its clinical efficacy, safety and acceptability with potential positive impacts on healthcare costs.


Author(s):  
Jayshree Satpute ◽  
Rajesh Gundre ◽  
Chandrakant Chate

Siravyadhana and Trishothadi Lepam application was intended for healthy wound healing. Probably it will have an understanding of underlying mechanism of relieving vascular stasis, reducing venous congestion and beginning of re-vascularization and other wound healing process. The Group-B showing maximum percentage of benefit followed by Group-A. Hence it can be concluded that overall benefit is found maximum in Group-A where Siravyadhana with Trishothadi Lepam was administered. The  drug  Trishothadi Lepam might be shown the efficacy due to Lekhana, Kledahara, Shoshana, Shotha & Dahahara, RaktaShodhaka and Twaka Prasadana properties. this procedure is found to be very much safe, simple, cost-effective, easily administered in the patients of foot ulcers leading them for complete healing avoiding the most unwanted outcome of amputation.


Author(s):  
Oorvi Kulkarni ◽  
Prashanth A. S.

A chronic venous leg ulcer is not so common in Ayurvedic practices. But deep vein thrombosis is more common in clinics. Venous and arterial diseases are most usual cause of leg ulcers accounting to 60 to 80% of them. On an average 33 to 60% of these ulcers are present for more than 6 weeks and therefore referred to as venous leg ulcers. The case reported here was as a result of repeated trauma with a history since 20 years. The treatment was given at IPD level diagnosing it as Upadrava Roopi Vatarakta with valid Chikitsa Siddhanta. This case report provides us a guide lines that even a chronic ulcer can be healed with proper assessment of Dosha, Dhatu, Strotas involvement.


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