Front-end Design Optimization for Ionoacoustic 200 MeV Protons Beam Monitoring with Sub-millimeter Precision for Hadron Therapy Applications

For precise treatment purposes in hadron therapy, the beam has to be monitored in real time without being degraded. For the first time, silicon strip detectors have been fabricated over an area as large as 20.25 cm2 with an ultra low thickness of 20 or 10 μm in order to reduce the material budget and hence the beam degradation provoked by the sensor. In this work, we describe the novel design and its fabrication process. Afterwards, we present the first electrical characterizations compared to the application requirements. The novel devices and their fabrication process are validated through measurements and simulations. A low strip-to-strip behavior variation is demonstrated as well as a very good interstrip insulation and a very low leakage current. These novel fabricated devices constitute a very promising technology for future hadron therapy beam monitoring.

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Use of Truncated Finite Element Modeling for Efficient Design Optimization of an Automotive Front End Structure

10.4271/2015-01-0496 ◽

2015 ◽

Cited By ~ 7

Author(s):

Anindya Deb ◽

Ranga Srinivas Gunti ◽

Clifford Chou ◽

Utpal Dutta

Keyword(s):

Finite Element ◽

Finite Element Modeling ◽

Design Optimization ◽

Efficient Design ◽

Element Modeling ◽

Front End

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Application of the Medipix2 technology to space radiation dosimetry and hadron therapy beam monitoring

Radiation Measurements ◽

10.1016/j.radmeas.2011.08.026 ◽

2011 ◽

Vol 46 (12) ◽

pp. 1610-1614 ◽

Cited By ~ 7

Author(s):

Lawrence Pinsky ◽

Nicholas Stoffle ◽

Anton Empl ◽

Jan Jakubek ◽

Stanislav Pospisil ◽

...

Keyword(s):

Radiation Dosimetry ◽

Space Radiation ◽

Hadron Therapy ◽

Space Radiation Dosimetry ◽

Beam Monitoring

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Thermo-mechanical analysis and design optimization of front-end compound refractive lens

10.1117/12.568105 ◽

2004 ◽

Cited By ~ 5

Author(s):

Lin Zhang ◽

Anatoly A. Snigirev ◽

Irina I. Snigireva ◽

Graham Naylor ◽

Anders Madsen ◽

...

Keyword(s):

Design Optimization ◽

Mechanical Analysis ◽

Analysis And Design ◽

Front End ◽

Refractive Lens

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Analysis and Design Optimization of Diode Front-End Rectifier Passive Components for Voltage Source Inverters

IEEE Transactions on Power Electronics ◽

10.1109/tpel.2008.2001895 ◽

2008 ◽

Vol 23 (5) ◽

pp. 2278-2289 ◽

Cited By ~ 19

Author(s):

Fei Wang ◽

Gang Chen ◽

D. Boroyevich ◽

S. Ragon ◽

M. Arpilliere ◽

...

Keyword(s):

Design Optimization ◽

Voltage Source ◽

Passive Components ◽

Voltage Source Inverters ◽

Analysis And Design ◽

Front End

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Acoustic Bragg Peak Localization in Proton Therapy Treatment: Simulation Studies

Proceedings ◽

10.3390/ecsa-6-06533 ◽

2019 ◽

Vol 42 (1) ◽

pp. 71

Author(s):

Jorge Otero ◽

Ivan Felis ◽

Miguel Ardid ◽

Alicia Herrero ◽

José A. Merchán

Keyword(s):

Energy Deposition ◽

Bragg Peak ◽

Local Heating ◽

Therapy Monitoring ◽

Thermal Source ◽

The Finite Element Method ◽

Hadron Therapy ◽

Beam Monitoring ◽

The Brain ◽

Therapy Treatment

A full chain simulation of the acoustic hadron therapy monitoring for brain tumors is presented in this work. For the study, a proton beam of 100 MeV was considered. In the first stage, Geant4 was used to simulate the energy deposition and to study the behavior of the Bragg peak. The energy deposition in the medium produced local heating that can be considered instantaneous with respect to the hydrodynamic time scale producing a sound pressure wave. The resulting thermoacoustic signal was subsequently obtained by solving the thermoacoustic equation. The acoustic propagation was simulated by the Finite Element Method (FEM) in the brain and the skull, where a set of piezoelectric sensors were placed. Lastly, the final received signals in the sensors were processed in order to reconstruct the position of the thermal source and, thus, to determine the feasibility and accuracy of acoustic beam monitoring in hadron therapy.

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