scholarly journals RETROSPECTIVE STUDY OF OVARIAN TUMORS AND TUMOR LIKE LESIONS

1969 ◽  
Vol 3 (1) ◽  
pp. 276-281
Author(s):  
NASIM AKHTAR
Keyword(s):  
Germ Cell ◽  
Mucinous Cystadenoma ◽  
Malignant Tumour ◽  
Serous Cystadenoma ◽  
Histological Type ◽  
Germ Cell Tumours ◽  
Neoplastic Lesion ◽  
Significant Difference ◽  
Ovarian Tumours ◽  
Operative Findings

Objective: To find frequency of various Neoplastic and non-neoplastic lesion of the ovaries and to analyzeits clinical presentation.Method: This study was conducted from first July 2007 to 30lh June 2010 in Gynae unit B of DHQ Mardan.All the cases of ovarian Tumours which were initially recruited after ultrasonography and were laterconfirmed by open surgery were included in the study Patients record files were used for collection ofrelevant data including detailed history, examination, investigations and operative findings. All thespecimens were sent for histopathology diagnosis to histopathology section lady reading hospital and a copyof report was attached in patients record files.Result: Out of 7574 Gynanocological admission 191 cases (2.5%) of ovarian Tumours were detected. Nonneo-plastic lesion were more common 98 (51.31%) than neoplastic lesion 93 (48.69%). Among theneoplastic lesion 69.89% were benign while 30% were malignant, serous cystadenoma were the commonestbenign Tumours (35.48%) followed by mucinous cystadenoma (21.50%). Serous cyst adenocarcinoma(10.75%) was the commonest malignant Tumour followed by mucinous cystadenomcarcinoma (8.6%).Average age at presentation was 57 years for malignant ephithelial Tumours, 40 years for gonadal stromalTumours and 22.5 % for germ cell Tumours. There was significant difference in the mean age for benign andmalignant ovarian tumours(34 versus52 p =0.0001)Conclusion:Epithelial ovarian Tumours are the commonest Tumours followed by Germ cell Tumours. Agehas strong correlation with the histological type of the Tumour. Grade, histological type and age of thepatient are important prognostic factors. Ultrasound assessment of risk of malignancy favours better patientmanagement. Menstrual irregularities ,mass and pain abdomen were the commonest clinical presentations.Keywords: Ovarian Tumours, Ovarian neoplasm, Ovarian non-neoplastic lesion.

scholarly journals STUDY OF CLINICOPATHOLOGICAL SPECTRUM OF OVARIAN NEOPLASMS WITH SPECIAL REFERENCE TO EXPRESSION OF ER AND PR IN MALIGNANT LESIONS

2020 ◽  
pp. 67-69
Author(s):  
Sujata Ganguli ◽  
Keya Basu ◽  
Ranjana Bandyopadhyay
Keyword(s):  
Germ Cell ◽  
Special Reference ◽  
Reproductive System ◽  
Ovarian Neoplasms ◽  
Germ Cell Tumours ◽  
Female Reproductive System ◽  
Gynaecological Malignancy ◽  
Ovarian Tumours ◽  
Epithelial Tumours ◽  
Malignant Lesions

Ovarian carcinoma is the second most common carcinoma of the female reproductive system .It is the leading cause of death from gynaecological malignancy .The purpose of this study is to observe the clinicopathological spectrum of ovarian neoplasms with the expression of ER and PR in the different malignant lesions .A total of 156 cases of ovarian tumours were included in this study, and surface epithelial tumours were found to be the commonest neoplasm followed by germ cell tumours. Expression of ER and PR was found to be highest in Serous and Endometrioid tumours. PR Negative cases showed a higher grade and stage.

An Overview of Ovarian Tumours at B.P. Koirala Memorial Cancer Hospital, Nepal

2019 ◽  
Vol 3 (1) ◽  
pp. 44-48
Author(s):  
Chin Bahadur Pun ◽  
Sadina Shrestha ◽  
Ranjan Raj Bhatta ◽  
Greta Pandey ◽  
Suraj Uprety ◽  
...  
Keyword(s):  
Mucinous Cystadenoma ◽  
Cystic Teratoma ◽  
Serous Cystadenoma ◽  
Serous Cystadenocarcinoma ◽  
Cancer Hospital ◽  
Benign Ovarian Tumours ◽  
Serous Cystadenomas ◽  
Ovarian Tumours ◽  
Epithelial Tumours ◽  
Yolk Sac Tumour

Introduction: Ovarian cancer is the seventh most commonly diagnosed cancer among women in the world. This study was conducted with the aim to find out different histological types of ovarian tumours reported at B.P. Koirala Memorial Cancer Hospital (BPKMCH), Chitwan, Nepal. Methods: This was a retrospective study carried out at the Department of Pathology of BPKMCH from January 1, 2018 to December 31, 2018. This study included the patients who were operated at BPKMCH or referred cases from elsewhere, but the specimen was processed and reported at BPKMCH. All the data were retrieved and analyzed from the records of Pathology Department. Results: Altogether 87 cases of ovarian tumours were reported during the study period. Out of which, 31 cases were benign ovarian tumours whereas 56 cases were malignant ovarian tumours. Both benign and malignant ovarian tumours were most common in age group 41 to 50 years of age. Among benign ovarian tumours, 12 cases were serous cystadenoma, 7 cases mucinous cystadenoma, 6 cases mature cystic teratoma, 2 cases serous cyst adenofibroma, 2 cases benign Brenner tumour and 2 endometroid cystadenoma. Among malignant ovarian tumours, 33 cases were serous cystadenocarcinoma, 11 cases mucinous cystadenocarcinoma, 2 cases immature teratoma, 3 cases were malignant sex cord stromal tumours (granulosa cell tumour), 2 cases dysgerminoma, 1 case yolk sac tumour, 1 case endometroid carcinoma and 3 cases were metastatic adenocarcinoma. Conclusion: Surface epithelial tumours were most common ovarian tumours in this study. Serous cystadenomas were most common benign ovarian tumours whereas serous cystadenocarcinomas were the most common malignant ovarian tumours.  

scholarly journals Comprehensive study of ovarian tumours in Kathmandu University Hospital

2018 ◽  
Vol 7 (4) ◽  
pp. 173-179
Author(s):  
Suman Raj Tamrakar ◽  
Ramesh Makaju ◽  
Abha Shrestha ◽  
Suresh Kayastha
Keyword(s):  
Cystic Teratoma ◽  
Malignant Tumour ◽  
University Hospital ◽  
P Value ◽  
Age Group ◽  
Primary Malignancy ◽  
Benign Ovarian Tumours ◽  
Significant Difference ◽  
Ovarian Tumours ◽  
The Mean

Background: Ovarian tumours account for 15% to 25% of all primary malignancy and the leading cause of death from gynaecolgical malignancies. There are limited publications related to ovarian tumours from Nepal. Ovarian related surgeries are the common surgeries in Kathmandu University Hospital. This study aims to provide basic information related to ovarian tumours from this geographical region of Nepal. Objectives: To review the nature of ovarian problems and certain socio-demographic information namely: caste, age, address and co-morbid condition of the patients presenting with ovarian problems. Methodology: This is a retrospective study of patients seeking surgical treatment of ovarian lesions in Kathmandu University Hospital from January 1, 2011 to June 30, 2018. This study was undertaken by reviewing the inpatient, outpatients and OT records in the Department of Obstetrics and Gynaecology and the records from Department of Pathology. All the files and computer records were reviewed and analyzed for nature of ovarian problems and certain demographic variables. Results: Out of the 860 cases, about 61% were non-neoplastic while benign ovarian tumours and malignant ovarian tumours were 35% and 3.7 % respectively. Almost one third of the cases were of Brahmin/Chhetri (37.3%) and 58.3% of the patients were from Kavre district. Mean age of the patients with ovarian problems was 34.89±11.15 years (range 12-72 years). There was no statistically significant difference between the mean age of patients with non-neoplastic ovarian lesions and neoplastic ovarian lesions (p value = 0.3371). There was statistically significant difference between the mean age of patients with benign ovarian tumours and malignant ovarian tumours (p value = 0.0001). And malignant ovarian tumours were significantly high among patients above 41 years in comparison to benign ovarian tumours of same age group (p value = 0.0008). Out of 32, ten malignant ovarian tumours occurred in relatively young age group. Of the 860 ovarian lesions, 438 and 422 ovarian lesions were removed through open technique and laparoscopic techniques respectively. Mature cystic teratoma (64.1%) was the commonest benign tumor and serous cyst adenocarcinoma (43.8%) was the commonest malignant tumour in this study. Conclusion: Ovarian tumours are one of the gynaecological diagnoses in Kathmandu University Hospital. If only ovarian neoplasms are considered, most of the ovarian tumours are benign and few are malignant. Minimal invasive surgeries are possible, except that for malignant ovarian tumours.

scholarly journals A Study on Histopathological Pattern of Ovarian Tumours in Chittagong Medical College Hospital

2020 ◽  
Vol 19 (2) ◽  
pp. 13-17
Author(s):  
Mahmuda Begum ◽  
Md Mukhlesur Rahman ◽  
Mahmuda Jahan ◽  
Zillur Rahman ◽  
Shahanara Chowdhury
Keyword(s):  
Germ Cell ◽  
Germ Cell Tumour ◽  
Malignant Tumour ◽  
Ovarian Tumour ◽  
Medical College Hospital ◽  
Cell Tumour ◽  
College Hospital ◽  
Medical College ◽  
Ovarian Tumours ◽  
Serous Cyst

Background: Ovarian tumours may either be asymptomatic, found on the routine ultrasound examination or symptoms may be vague till the patient has an acute emergency like torsion or rupture of a benign cyst. The worst is late presentation of malignant ovarian tumour. There is marked variation in the presentation of the tumour as well as in histological types. This study was under taken to analyse modes of presentation and various histopathological patterns of ovarian tumour. Materials and Methods: A total of 69 cases were selected consecutively. The age range was 13-70 years. This study was carried out in the Department of Pathology, Chittagong Medical College and Department of Gynaecology and obstetrics, Chittagong Medical College Hospital during the period from July 2013 to June 2014. The specimens of ovarian tumours were subjected to histopathological examination in the histopathology section. Results : Out of 69 cases, 54(78.3%) were benign and 15(21.7%) were malignant tumour. There was no borderline malignancy in our study. The commonest histological pattern in this study was surface epithelial tumour 49(70.6%) including both benign and malignant tumour followed by germ cell tumour 6(8.7%). The commonest benign tumour was serous cyst cyst adenoma 23(33.4) and malignant tumour was serous cyst adenocarcinoma 5(7.2%). Conclusion : Surface epithelial tumours are the commonest variety of ovarian tumour followed by germ cell tumour. The histological type of ovarian tumour correlates with the prognosis of the tumour. Chatt Maa Shi Hosp Med Coll J; Vol.19 (2); July 2020; Page 13-17

Unexpected borderline ovarian tumours (BOT) in late pregnancy: challenges in management and review of literature

2020 ◽  
Vol 13 (12) ◽  
pp. e237970
Author(s):  
Elizabeth Ande ◽  
Silky Jain ◽  
Schahrazed Rouabhi ◽  
Wai Yoong
Keyword(s):  
Elective Caesarean Section ◽  
Mucinous Cystadenoma ◽  
Late Pregnancy ◽  
Ovarian Tumour ◽  
Serous Cystadenoma ◽  
Reproductive Age ◽  
Third Trimester ◽  
Borderline Ovarian Tumour ◽  
Younger Women ◽  
Ovarian Tumours

This case report describes a right-sided borderline ovarian tumour diagnosed unexpectedly following suspected torsion in the third trimester of pregnancy. The patient had had a right mucinous cystadenoma and left serous cystadenoma in her previous pregnancy and underwent bilateral ovarian cystectomy at the time of her first elective caesarean section. The management of borderline ovarian tumours is generally difficult in younger women of reproductive age and is made more complex by pregnancy. The authors share the challenges of managing this condition in pregnancy together with a review of the literature.

scholarly journals COLLISION TUMOUR IN OVARY;

2019 ◽  
Vol 26 (03) ◽  
Author(s):  
Afra Samad ◽  
Namra Mahmood ◽  
Arbaz Samad
Keyword(s):  
Mature Teratoma ◽  
Mucinous Cystadenoma ◽  
Serous Cystadenoma ◽  
Surface Epithelium ◽  
Granulosa Cell Tumour ◽  
Review Of Literature ◽  
The Third ◽  
Collision Tumour ◽  
Ovarian Tumours ◽  
Sex Cord Stromal Tumor

Most of the ovarian tumours are of surface epithelium and account for 65-75% of tumours.1 Serous cystadenoma constitutes 20% of ovarian tumours. Sex- cord stromal tumour is less common. Fibroma is the most common sex-cord stromal tumor comprising 70%.2 Tumors can present in a combination in ovary like teratoma and mucinous cystadenoma, granulosa cell tumour and mature teratoma and/or mucinous tumors.3 We report a rare case of combined serous cystadenoma and fibroma in a 55 years old female. Review of literature reveal only two such cases. To best of our knowledge this is the third case which is being report.

scholarly journals TO STUDY RELATION BETWEEN SIZE OF OVARY AND VARIOUS HISTOMORPHOLOGICAL PATTERNS

2020 ◽  
Vol 4 (11) ◽  
Author(s):  
Archna Ramole ◽  
Tanya Agrawal Chaurasia
Keyword(s):  
Tumour Size ◽  
Germ Cell Tumours ◽  
Malignant Tumours ◽  
Medical College ◽  
Neoplastic Lesion ◽  
Neoplastic Lesions ◽  
Ovarian Tumours ◽  
Epithelial Tumours ◽  
Benign Tumours ◽  
Gandhi Medical College

Background & Method: The present study is based on histomorphological evaluation in 214 cases of Ovarian neoplastic and non-neoplastic lesions received at the department of Pathology of a Gandhi Medical College, Bhopal from Apr 2017 to March 2019. Result: All lesions of size 03cm or less are non neoplastic. Of 133 non neoplastic cases, 72 are of size 4 to 6 cm, 36 cases of size 07to 10 cm and 11 cases are >10cm. Out of 47 benign neoplastic lesions 25 are more than 10 cm in size, 18 are of size 07 to 10 cm and 04 cases are of 04 to 06 cm in size.  24 out of 31 malignant cases are more than 10 cm in size, 05 cases are of size 07 to 10 cm and 02 cases are of size 04 to 06 cm. Of tumour size more than 10 cm, 25 are benign tumours and 24 are malignant tumours. Out of 59 cases of size 07 to 10 cm, 36 cases are non neoplastic, 18 cases are benign tumours and 05 are malignant tumours. Conclusion: Among the 214 cases, non neoplastic lesions (62.0%) were more common than the neoplastic lesion (38.0%). Overall incidence of malignancy was 14.4%, and it is 38% among neoplastic lesions. Among 133 non neoplastic lesions studied simple serous cyst (36%) was commonest followed by corpus luteal cyst (25%). Out of 81 tumours, surface epithelial tumours (67.6%) are the commonest ovarian tumours followed by germ cell tumours (24.7%). Keywords: Ovary, Size & Histomorphological. Study Designed: Observational Study.

scholarly journals Clinicopathological study of benign and malignant ovarian tumours and the role of HER2/neu and ER expression in these tumours

2019 ◽  
Vol 7 (6) ◽  
pp. 2132
Author(s):  
Nidhi Verma ◽  
Kriti Grover ◽  
S. P. Sharma ◽  
Priya Gupta ◽  
Preeti Singh ◽  
...  
Keyword(s):  
Germ Cell ◽  
Mature Teratoma ◽  
Germ Cell Tumours ◽  
Malignant Tumours ◽  
Positive Expression ◽  
Ovarian Tumours ◽  
Epithelial Tumours ◽  
Benign Tumours ◽  
Er Expression

Background: Ovarian cancers represent the 6th most common cancer among females and are the most common cause of death from gynaecological cancers in the world. The aim is to do clinicopathologic study of ovarian tumours along with evaluation of the expression of estrogen receptor (ER) and human epidermal growth factor receptor (HER2/neu).Methods: A total of 85 cases of ovarian tumors were studied and immunohistochemistry was performed with specific antibodies against ER and HER2/neu as per standard protocol.Results: In present study, surface epithelial tumours were the commonest type comprising 64 cases (75.2%), followed by Germ cell tumours, 17cases (20%) and sex cord stromal tumours, 04 cases (4.8%).Among the surface epithelial tumours , ER‑positive cases were higher in malignant (71.4%) tumours as compared to borderline tumours (33.3%) and benign tumours (7.7%) while Her2/neu positive cases were higher in borderline (66.7%) tumours as compared to malignant tumours (42.9%) and benign tumours (15.3%).Among the germ cell tumours, ER expression was positive in 62.5% cases of mature teratoma while HER2/neu expression was positive in only 12.5% cases of mature teratoma. None of the sex cord stromal tumours showed positive expression of ER and HER2/neu.Conclusions: Positive expression of estrogen receptors is seen predominantly in surface epithelial malignancies and in mature teratoma. It proves the mitogenic role of estrogen in ovarian tumours. Her-2 neu was expressed mainly in malignant tumours. This suggests their carcinogenic role. This also helps in differentiating borderline and malignant tumours.

scholarly journals A Study of Histomorphology of Ovarian Neoplasms

2018 ◽  
Vol 27 (1) ◽  
pp. 25-28
Author(s):  
Enamul Haque ◽  
Naila Huq ◽  
Abdullah Yusuf ◽  
Shahana Khanam ◽  
Kazi Monisur Rahman
Keyword(s):  
Germ Cell ◽  
Germ Cell Tumor ◽  
Malignant Tumor ◽  
Malignant Tumors ◽  
Mucinous Cystadenoma ◽  
Serous Cystadenoma ◽  
Ovarian Neoplasm ◽  
Cell Tumor ◽  
Benign Tumors ◽  
Diagnostic Center

Background: Ovarian malignancy is one of the most common causes of cancer deaths in females in Bangladesh. Due to poor early symptoms and lack of screening protocol, it is detected later in the clinical course of the disease. It is also one of the most treatable tumors because majorities are sensitive to chemo-radiation. An accurate histology is often a critical factor in achieving optimum treatment response. Objective: To study the frequency and histological patterns of neoplastic ovarian lesions. Methodology: A retrospective cross sectional study was done. We analyzed the data compiled from ovarian lesions biopsied and reported in a private diagnostic center from January 2008 to December 2015. Results: Out of 231 ovarian specimens only 66 were neoplastic lesions, while the rest were nonneoplastic cysts. The age range was 9 to 65 years with a mean of 36.58 ±10.45. 73 percent (48) were benign, 6.01 percent (4) were borderline and 21.21 percent (14) were malignant. Surface epithelial tumors were the most common ovarian neoplasm (n=48; 72.73%) followed by germ cell tumor (n=14; 21.21%) and sex cord stromal tumor (n=4; 6.01%). Serous cystadenoma was the commonest benign tumor (23) followed by dermoid cyst (11), and mucinous cystadenoma (10). Only 4 borderline malignant tumors were found; 03 of which were mucinous and 01 serous. The number of malignant tumor was 18. Malignant mucinous neoplasm was the commonest, in both invasive carcinoma (05) and borderline group (03). Conclusion: Benign ovarian neoplasm was more common than malignant ones. Surface epithelial tumor was the frequent group followed by germ cell tumor. Serous cystadenoma was most common among benign tumors whereas mucinous cystadenocarcinoma was the commonest malignant tumor. J Dhaka Medical College, Vol. 27, No.1, April, 2018, Page 25-28

scholarly journals A retrospective study on surgical management of ovarian tumours in a teritary care semiurban hospital

2017 ◽  
Vol 6 (10) ◽  
pp. 4429
Author(s):  
S. Divya Ranjitha ◽  
Kavitha Karthikeyan ◽  
Amrita Priscilla Nalini
Keyword(s):  
Retrospective Study ◽  
Surgical Management ◽  
Preoperative Evaluation ◽  
Mucinous Cystadenoma ◽  
Serous Cystadenoma ◽  
Ovarian Tumors ◽  
Histopathological Diagnosis ◽  
Simple Cyst ◽  
Ovarian Tumours ◽  
Real Challenge

Background: The prevalance of ovarian tumors is around 1-3%. The accurate diagnosis and appropriate management of ovarian tumors is a real challenge to gynaecologists. The aim of the study was to analyse the risk factors, clinical presentation, surgical procedure and histopathological report in patients with surgically managed ovarian tumours.Methods: We conducted a retrospective study by collecting the data of patients operated in the department of Obstetrics and Gynecology at Chettinad Hospital and Research Institute, Kelambakkam. A total of 118 case records were studied.Results: 20.3% were nulliparous. 79.7% were multiparous. 10.2% were <20 years, 47.2% were 20-40 years, 39.2% were 40-60 years, 3.4% were >60 years. 72.9% were premenopausal. 27.1% were postmenopausal. 25.4% presented with acute abdominal pain, 11.9% with mass abdomen, 30.5% with chronic pain abdomen and 32.2% were incidentally diagnosed. 20.4% underwent ovarian cystectomy, 18.6% ovariotomy, 30.5% salpingoophorectomy and 30.5% total abdominal hystrectomy with bilateral salpingoophorectomy. Most common histopathology report was simple cyst in 44.%. 31.3% had serous cystadenoma, 9.3% had mucinous cystadenoma, 9.3% had teratoma, 2.5% had brenner tumour, 1.7% borderline tumours and 1.7% malignancy (Serous cystadenocarcinoma).Conclusions: Elective surgical management of ovarian tumours is better option for reducing emergency laparotomies for torsion and rupture and also for obtaining a conclusive histopathological diagnosis in suspicious cases. The choice between laparoscopy and laparotomy should made after making appropriate preoperative evaluation.

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