scholarly journals Possibilities of bioimpedance method of investigation of elderly patients with chronic heart failure

Author(s):  
V. V. Kirillova ◽  
L. A. Sokolova ◽  
V. N. Meshchaninov ◽  
V. S. Myakothyh

Introduction. Diagnostics of congestive events in chronic heart failure (CHF) in elderly people is increasingly relevant due to the general aging of the population, which determines the search for new research methods. The aim is to evaluate the diagnostic capabilities of bioimpedance method in determining the severity of congestion in elderly patients with CHF. Materials and methods. 86 elderly patients with CHF of different clinical stages were examined, 36.0% of them were burdened with varicose vein disease of the lower limbs. Total body water content was assessed by active impedance at 50 kHz, extracellular fluid content — at 5 kHz. Results. Active resistance at 50 kHz in patients with CHF II B was 473.92±29.39, with CHF II A - 569.24±58.97, with CHF I — 601.33±24.64 ohms, respectively, at 5 kHz — 555.52±27.44, 633.50±51.32 and 722.50±15.85 ohms respectively. No total and/or extracellular fluid retention was detected in CHF II A without lower limb varicosity, and in 10 (58.8%) patients — in cases of its presence. Retention of total and/or extracellular fluid was detected in 74.4% of CHF stage II B patients, and 48.3% of them had varicose vein disease of the lower limbs. Discussion. Patients with CHF stage II B have the highest amount of total and extracellular fluid in the body compared to patients with CHF stage II A and CHF stage I, but the method is insensitive for diagnosis of fluid retention in the small circle of the circulation and differential diagnosis of the genesis of edema in varicose vein disease of the lower limbs. Conclusion. Bioimpedance imaging can be used for additional diagnostics of CHF in elderly patients in order to estimate the amount of total/extracellular fluid in the body to build personalized treatment and prevention programs.

2021 ◽  
Vol 6 (3) ◽  
pp. 22-36
Author(s):  
Yu. G. Gorb ◽  
◽  
V. I. Strona ◽  
O. V. Tkachenko ◽  
S. A. Serik ◽  
...  

The features of the pathogenesis and course of type 2 diabetes mellitus and diseases of the cardiovascular system comorbid with it are considered in patients of elderly and old age – coronary artery disease, arterial hypertension, chronic heart failure. The leading role of insulin resistance, hyperglycemia and dyslipidemia in the development of metabolic, homeostatic disorders, the formation of oxidative stress and endothelial dysfunction, which, together with age-related changes in the body, contribute to the progression of type 2 diabetes mellitus and microvascular complications, primarily diabetic cardiomyopathy. Particular attention is paid to the relationship between cognitive impairment, type 2 diabetes mellitus and chronic heart failure. The main factors that worsen the course and prognosis of type 2 diabetes mellitus in elderly patients, in particular, hypertension, atrial fibrillation, diabetic polyneuropathy, nephropathy, and other concomitant diseases, have been identified. Lack of compensation for type 2 diabetes due to metabolic disorders leads to the development of diabetic cardiovascular autonomic neuropathy, diabetic cardiomyopathy along with the progression of atherosclerotic lesions of different localization. The course of type 2 diabetes in these patients is often complicated by geriatric syndrome, which contains a set of cognitive impairment, senile weakness, depression, functional disorders, polymorbidity. Cognitive disorders negatively affect the course of type 2 diabetes and its complications, significantly disrupting the process of teaching patients the methods of self-control, following the advice of a doctor. It is noted that the management of this category of patients should be individual and include adequate correction of hyperglycemia to prevent microvascular complications and hypoglycemic conditions, as well as reduce cardiovascular mortality and maintain quality of life. Rational selection of drugs, taking into account the factors that determine their impact on the body of elderly patients with type 2 diabetes mellitus and possible adverse drug reactions, will increase the effectiveness and safety of drug therapy in such patients. Optimizing therapeutic approaches for elderly patients with type 2 diabetes requires effective changes in the health care system to provide them with comprehensive medical and social care according to their special needs


2007 ◽  
Vol 8 (8) ◽  
pp. 608-612 ◽  
Author(s):  
Angela Beatrice Scardovi ◽  
Claudio Coletta ◽  
Renata De Maria ◽  
Silvia Perna ◽  
Nadia Aspromonte ◽  
...  

ESC CardioMed ◽  
2018 ◽  
pp. 1781-1787
Author(s):  
Perry Elliott

Heart failure refers to a state in which the cardiac output, no longer compensated by endogenous mechanisms, fails to meet the metabolic demands of the body. Clinically, it is defined by symptoms of breathlessness, fatigue, fluid retention, and a cardiac structural or functional abnormality. Most cases of heart failure are caused by coronary artery disease, hypertension, diabetes, and valvular heart disease, but the risk of heart failure also depends on genetic predisposition for the causative disorder as well as genetic variation that modulates the maladaptive pathophysiological response to pathophysiological stressors and the response to therapy. In a small, but almost certainly underdiagnosed proportion of cases, heart failure is caused by Mendelian genetic disorders of heart muscle (cardiomyopathies) that are mostly inherited as autosomal dominant traits characterized by locus and allelic heterogeneity and highly variable clinical expression. This chapter briefly reviews the clinical approach to the diagnosis of genetic disorders that cause heart failure and the role of genetic testing in everyday practice.


2005 ◽  
Vol 14 (12) ◽  
pp. 25
Author(s):  
L. Ingle ◽  
R.J. Shelton ◽  
A.S. Rigby ◽  
S. Nabb ◽  
A.L. Clark ◽  
...  

Author(s):  
Barry L. Karon ◽  
Naveen L. Pereira

Heart failure is a clinical syndrome characterized by the inability of the heart to maintain adequate cardiac output to meet the metabolic demands of the body while still maintaining normal or near-normal ventricular filling pressures. Heart failure may be present at rest, but often it is present only during exertion as a result of the dynamic nature of cardiac demands. For correct treatment of heart failure, the mechanism, underlying cause, and any reversible precipitating factors must be identified. Typical manifestations of heart failure are dyspnea and fatigue that limit activity tolerance and fluid retention leading to pulmonary or peripheral edema. The most recent proposed categorization divided the cardiomyopathies into primary and secondary cardiomyopathies, and the primary disorders are further subdivided as genetic, acquired, or mixed. Although this proposal takes into account our progressive understanding of this heterogeneous group of disorders, the previous phenotypic classification of dilated, hypertrophic, and restrictive diseases still provides utility in day-to-day understanding and management of these disorders.


2020 ◽  
Vol 27 ◽  
pp. 100497 ◽  
Author(s):  
Masayuki Sato ◽  
Yasuhiko Sakata ◽  
Kenjiro Sato ◽  
Kotaro Nochioka ◽  
Masanobu Miura ◽  
...  

2011 ◽  
Vol 148 (2) ◽  
pp. 199-203 ◽  
Author(s):  
Giuseppe Caminiti ◽  
Maurizio Volterrani ◽  
Giuseppe Marazzi ◽  
Anna Cerrito ◽  
Rosalba Massaro ◽  
...  

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