scholarly journals Effect of high- intensity interval training on tissue changes of collagen type 1 and fibrosis percent in male rats with myocardial infarction

2021 ◽  
Vol 23 (2) ◽  
pp. 267-274
Author(s):  
Rahman Soori ◽  
Zahra Mosayebi ◽  
Parisa Pournemati ◽  
Ali Akbarneghad ◽  
◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
High Intensity ◽  
Collagen Type ◽  
Interval Training ◽  
Male Rats ◽  
High Intensity Interval Training ◽  
Tissue Changes ◽  
High Intensity Interval ◽  
Collagen Type 1

High-Intensity Interval Training and Hypoglycemia Minimization in Adults with Type 1 Diabetes (HIIT HYPO T1D Study)

Diabetes ◽  
2018 ◽  
Vol 67 (Supplement 1) ◽  
pp. 743-P
Author(s):  
ANGELA S. LEE ◽  
KIMBERLEY L. WAY ◽  
NATHAN A. JOHNSON ◽  
STEPHEN M. TWIGG
Keyword(s):  
Type 1 Diabetes ◽  
High Intensity ◽  
Interval Training ◽  
High Intensity Interval Training ◽  
High Intensity Interval

scholarly journals Effect of high-intensity interval training on glycemic control in adults with type 1 diabetes with overweight or obesity: a randomized controlled trial with partial cross-over

2020 ◽  
Author(s):  
Angela S Lee ◽  
Nathan A Johnson ◽  
Margaret McGill ◽  
Jane Overland ◽  
Connie Luo ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Glycemic Control ◽  
High Intensity ◽  
Intervention Group ◽  
Interval Training ◽  
Control Group ◽  
High Intensity Interval Training ◽  
High Intensity Interval ◽  
Overweight Or Obesity

<b>Objective:</b> To study the effect of 12 weeks of high-intensity interval training (HIIT) on glycemic control in adults with type 1 diabetes with overweight or obesity. <p> </p> <p><b>Research Design and Methods:</b> Thirty inactive adults with type 1 diabetes who had BMI≥25kg/m<sup>2</sup> and HbA1c≥7.5% were randomized to 12 weeks of either: HIIT exercise intervention consisting of 4x4 minutes HIIT (85-95% HRpeak) performed thrice weekly, or usual care control. In a partial cross-over design, the control group subsequently performed the 12-week HIIT intervention. The primary endpoint was the change in HbA1c from baseline to 12 weeks. Glycemic and cardiometabolic outcomes were measured at 0, 12, and 24 weeks.</p> <p> </p> <p><b>Results:</b> Participants were aged 44±10 years, with diabetes duration 19±11 years, and BMI 30.1±3.1 kg/m<sup>2</sup>.<sup> </sup>HbA1c decreased from 8.63 ± 0.66% at baseline to 8.10 ± 1.04% at 12 weeks in the HIIT intervention group (p=0.01), however this change was not significantly different to the control group (HIIT -0.53 ± 0.61%, control -0.14 ± 0.48%, p=0.08). In participants who undertook at least 50% of the prescribed HIIT intervention, the HbA1c reduction was significantly greater than control (HIIT -0.64 ± 0.64% (n=9), control -0.14 ± 0.48% (n=15), p=0.04). There were no differences in insulin dose, hypoglycemia on continuous glucose monitoring, blood pressure, blood lipids, body weight or body composition between groups. </p> <p> </p> <p><b>Conclusions:</b> <a>Overall, there was no significant reduction in HbA1c with a 12-week HIIT intervention in adults with type 1 diabetes. However glycaemic control may improve for people who undertake HIIT with greater adherence.</a></p>

scholarly journals High-intensity interval training-induced hypertrophy in gastrocnemius muscle via improved IGF-I/Akt/FoxO and myostatin/Smad signaling pathways in rats

2020 ◽  
Vol 107 (2) ◽  
pp. 220-230 ◽  
Author(s):  
Soheil Biglari ◽  
Alireza Ghardashi Afousi ◽  
Farnoosh Mafi ◽  
Fatemeh Shabkhiz
Keyword(s):  
Signal Transduction ◽  
High Intensity ◽  
Muscle Hypertrophy ◽  
Gastrocnemius Muscle ◽  
Interval Training ◽  
Male Rats ◽  
Signal Transduction Pathways ◽  
High Intensity Interval Training ◽  
Igf I ◽  
High Intensity Interval

AbstractObjectiveIt has been shown that high-intensity interval training (HIIT) leads to skeletal muscle hypertrophy; however, its mechanisms of cellular and molecular regulation are still unclear. The purpose of this study was to investigate the effect of HIIT on muscle hypertrophy and major signal transduction pathways.Design12 male rats were randomly divided into two groups: control and HIIT. The exercise group performed 30-min HIIT in each session (5 × 4-min intervals running at 85–95% VO2max separated by 2-min active rest at 55–60% VO2max), 3 days/week for 8 weeks. Muscle fiber cross-sectional area (CSA) and the expression of signal transduction pathway proteins were determined in the gastrocnemius muscle.ResultsIn the HIIT group, the expression of IGF-I, IGF-IR Akt, p-Akt, AMPKα, p-AMPKα and follistatin increased significantly, whereas a significant decrease was observed in the expression of FoxO1, p-FoxO1, myostatin, ActRIIB, Smad2/3 and p-Smad2/3 (P < 0.05). However, there were no significant differences between the HIIT and control groups in the expression of mTOR, p-mTOR, P70S6K, and p-P70S6K (P > 0.05). In addition, CSA and gastrocnemius muscle weight increased significantly in the HIIT group (P < 0.05).ConclusionsHIIT induced muscle hypertrophy by improving IGF-I/Akt/FoxO and myostatin/Smad signal transduction pathways.

scholarly journals High-Intensity Interval Training in Cardiac Rehabilitation: Impact on Fat Mass in Patients With Myocardial Infarction

2019 ◽  
Vol 94 (9) ◽  
pp. 1718-1730 ◽  
Author(s):  
Yaoshan Dun ◽  
Randal J. Thomas ◽  
Jose R. Medina-Inojosa ◽  
Ray W. Squires ◽  
Hsuhang Huang ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Cardiac Rehabilitation ◽  
Fat Mass ◽  
High Intensity ◽  
Interval Training ◽  
High Intensity Interval Training ◽  
High Intensity Interval

scholarly journals The Effect of Two Types of High-Intensity Interval Training on Serum Value of GH and IGF-1 in Overweight Nurses

2020 ◽  
Vol 11 (4) ◽  
Author(s):  
Sahar Avazpour ◽  
Jamal Fazell Kalkhoran ◽  
Karamat Avazpour ◽  
Fatemeh Mohseni
Keyword(s):  
High Intensity ◽  
Interval Training ◽  
Control Group ◽  
High Intensity Interval Training ◽  
Significant Difference ◽  
Group 2 ◽  
High Intensity Interval ◽  
Group 1

Background: Growth hormone and insulin-like growth factor 1 are anabolic hormones that play a vital role in the growth of various physical organs. Exercise is one of the stimuli that affect GH and IGF-1 secretion. Objectives: This study aimed to compare the effect of two types of high-intensity interval training (HIIT) on plasma levels of GH and IGF-l in overweight nurses. Methods: In this study, 27 nurses were voluntarily selected and randomly assigned to three groups (9 participants for each group): 1. HIIT (type 1), including eight seconds of spring running and 12 seconds of active recovery, 2. HIIT (type 2), including a 40-meter shuttle run with maximum speed, 3. control. HIIT (type 1) was performed for four weeks, three sessions per week, each session 6 - 9 min with more than 90% HRmax. HIIT (type 2) was applied for four weeks, three sessions per week, with more than 90% HRmax. The control group did not participate in any training protocol. The serum value of GH and IGF-1 were compared in three groups. The data were analyzed by the dependent t-test and ANOVA. One-way analysis of variance (ANOVA) was used to analyze the intergroup data at P ⟨ 0.05. Results: The results showed that HIIT (type 1) and (type 2) significantly increased plasma GH (P = 0.032 in group 2 and P = 0.010 in group 1) and IGF-l (P = 0.004 in group 2 and P = 10.013 in group 1) levels in nurses. The results showed a significant difference in the variables (GH and IGF-l) among HIIT (type 1), HIIT (type 2), and control groups. Conclusions: It can be concluded that four weeks of adverse intermittent exercises are effective in increasing the concentration of GH and IGF-1 serum and decreased percentage body fat in young nurses with overweight, and proportional to the intensity of the exercise protocol response rate is different.

High intensity interval training decreases the expressions of KIF5B and Dynein in Hippocampus of Wistar male rats

Gene ◽  
2019 ◽  
Vol 704 ◽  
pp. 8-14
Author(s):  
Hadi Kerendi ◽  
Masoud Rahmati ◽  
Rahim Mirnasuri ◽  
Abdolreza Kazemi
Keyword(s):  
High Intensity ◽  
Interval Training ◽  
Male Rats ◽  
High Intensity Interval Training ◽  
High Intensity Interval ◽  
Wistar Male Rats

High-intensity interval training increase GATA4, CITED4 and c-Kit and decreases C/EBPβ in rats after myocardial infarction

Life Sciences ◽  
2019 ◽  
Vol 221 ◽  
pp. 319-326 ◽  
Author(s):  
Nasim Naderi ◽  
Mohammad Hemmatinafar ◽  
Abbas Ali Gaeini ◽  
Aida Bahramian ◽  
Alireza Ghardashi-Afousi ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
High Intensity ◽  
Interval Training ◽  
High Intensity Interval Training ◽  
High Intensity Interval
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