scholarly journals Formulasi Pangan Fungsional Tinggi Kalori Tinggi Protein: Biskuit Ubi Jalar-Ikan Gabus (Big@Bus)

2021 ◽  
Vol 12 (2) ◽  
pp. 199-209
Author(s):  
Cicilia Windiyaningsih ◽  
Yeny Sulistyowati ◽  
Yeni Ariestanti
Keyword(s):  

Peningkatan kasus TB merupakan tantangan bagi tenaga kesehatan dan sektor terkait dalam pencegahan dan penanganan TB secara terpadu dan komprehensif. Propinsi DKI di urutan kedua teratas di Indonesia. Perkembangan penanggulangan TB belum menggembirakan dan permasalahan TB masih belum dapat diselesaikan. Dalam menangani permasalahan untuk penderita TB, selain istirahat dan obat, diperlukan diet yang sehat dan tepat untuk membantu pemulihan penderita TB. Dietnya adalah Diet Tinggi Kalori Tinggi Protein. Sumber protein hewani yang memiliki potensi besar adalah ikan gabus (Ophiocephalus striatus).  Selain sumber makanan tinggi protein, diet yang diharapkan bisa mempercepat proses penyembuhan TB dengan diet tinggi kalori. Dari kelompok umbi-umbian, ada ubi jalar yang berasa manis, mengandung karbohidrat kompleks disertai vitamin dan mineral yang mudah dicerna. Makanan tambahan berbasis pangan lokal yaitu biskuit dengan suplementasi tepung ikan gabus dan ubi jalar dapat menjadi pilihan sebagai PMT Pemulihan TB. Dalam penelitian ini metode yang digunakan adalah metode eksperimen. Pelaksanaan penelitian adalah formulasi biskuit ikan gabus dengan penambahan tepung ubi jalar (Formula Pangan BIG@BUS). Hasil uji organoleptik oleh panelis diketahui bahwa warna dari tepung dan rasa dari biskuit mendapatkan rata-rata tertinggi dari penilaian panelis. Sedangkan aroma tepung dan tekstur dari biskuit mendapatkan nilai rerata terendah dari panelis. Hasil pemeriksaan kandungan zat gizi pemeriksaan untuk tepung menjadi biskuit terjadi penurunan kadar zat gizi karena perubahan bentuk dan proses pengolahannya, kecuali kadar Lemak.Kata Kunci: Ikan Gabus, Ubi, TB

Author(s):  
F. G. Zaki

Addition of lithocholic acid (LCA), a naturally occurring bile acid in mammals, to a low protein diet fed to rats induced marked inflammatory reaction in the hepatic cells followed by hydropic degeneration and ductular cell proliferation. These changes were accompanied by dilatation and hyperplasia of the common bile duct and formation of “gallstones”. All these changes were reversible when LCA was withdrawn from the low protein diet except for the hardened gallstones which persisted.Electron microscopic studies revealed marked alterations in the hepatic cells. Early changes included disorganization, fragmentation of the rough endoplasmic reticulum and detachment of its ribosomes. Free ribosomes, either singly or arranged in small clusters were frequently seen in most of the hepatic cells. Vesiculation of the smooth endoplasmic reticulum was often encountered as early as one week after the administration of LCA (Fig. 1).


2013 ◽  
Author(s):  
Francesco Saverio Mennini ◽  
Simone Russo ◽  
Andrea Marcellusi ◽  
Giuseppe Quintaliani ◽  
Denis Fouque

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Sonja Christiane Bäßler ◽  
Ákos Kenéz ◽  
Theresa Scheu ◽  
Christian Koch ◽  
Ulrich Meyer ◽  
...  

AbstractMetabolic consequences of an energy and protein rich diet can compromise metabolic health of cattle by promoting a pro-inflammatory phenotype. Laminitis is a common clinical sign, but affected metabolic pathways, underlying pathophysiology and causative relationships of a systemic pro-inflammatory phenotype are unclear. Therefore, the aim of this study was to elucidate changes in metabolome profiles of 20 months old Holstein bulls fed a high energy and protein diet and to identify novel metabolites and affected pathways, associated with diet-related laminitis. In a randomized controlled feeding trial using bulls fed a high energy and protein diet (HEP; metabolizable energy [ME] intake 169.0 ± 1.4 MJ/day; crude protein [CP] intake 2.3 ± 0.02 kg/day; calculated means ± SEM; n = 15) versus a low energy and protein diet (LEP; ME intake 92.9 ± 1.3 MJ/day; CP intake 1.0 ± 0.01 kg/day; n = 15), wide ranging effects of HEP diet on metabolism were demonstrated with a targeted metabolomics approach using the AbsoluteIDQ p180 kit (Biocrates Life Sciences). Multivariate statistics revealed that lower concentrations of phosphatidylcholines and sphingomyelins and higher concentrations of lyso-phosphatidylcholines, branched chain amino acids and aromatic amino acids were associated with an inflammatory state of diet-related laminitis in Holstein bulls fed a HEP diet. The latter two metabolites share similarities with changes in metabolism of obese humans, indicating a conserved pathophysiological role. The observed alterations in the metabolome provide further explanation on the underlying metabolic consequences of excessive dietary nutrient intake.


2008 ◽  
Vol 67 (OCE5) ◽  
Author(s):  
F. Vitari ◽  
A. Morise ◽  
M. Formal ◽  
C. Garcia ◽  
K. Mace ◽  
...  

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