Translation of 15D questionnaire into Romanian language to study quality of life of cancer patients in Romania

2021 ◽  
Vol 2 (1) ◽  
pp. 1-9
Author(s):  
Adina Turcu-Stiolica ◽  
Mihaela-Simona Subtirelu

The 15D is a self-administered questionnaire for assessment of health-related quality of life, which contains 15 questions with 5 response options each. This research was aimed to translate the 15D questionnaire into Romanian to use for cancer patients and scientific community. The standard procedure of forward-backward translation was used in the translation procedure. The original questionnaire was given to two independent forward-translators (one English teacher and one experienced translator). The second step was the backward-translation with two English speakers who translated the first consensus version into English. The back translation was compared with the original version. The third step was the pilot-test on 15 patients and 10 healthy people. The patients’ obstacles in understanding and completing the questionnaires were reviewed and used to modify the questionnaires by the translation group. The final Romanian version of the 15D can be used for the next step of validation.

Author(s):  
Hester.R. Trompetter ◽  
Cynthia S. Bonhof ◽  
Lonneke V. van de Poll-Franse ◽  
Gerard Vreugdenhil ◽  
Floortje Mols

Abstract Purpose Chemotherapy-induced peripheral neuropathy ((CI)PN) becomes chronic in 30% of cancer patients. Knowledge of predictors of chronic (CI)PN and related impairments in health-related quality of life (HRQoL) is lacking. We examined the role of optimism in chronic (CI)PN severity and associated HRQoL in colorectal cancer (CRC) patients up to two years after diagnosis. Methods CRC patients from a prospective cohort study participated, with sensory peripheral neuropathy (SPN) 1 year after diagnosis (n = 142). Multivariable regression analyses examined the cross-sectional association between optimism (measured by the LOT-R) and SPN severity/HRQoL (measured by the EORTC QLQ-CIPN20 and QLQ-C30), as well as the prospective association in a subsample that completed measures 2 years after diagnosis and still experienced SPN (n = 86). Results At 1-year follow-up, higher optimism was associated with better global HRQoL, and better physical, role, emotional, cognitive, and social functioning (all p < .01). Optimism at year one was also prospectively associated with better global HRQoL (p < .05), and emotional and cognitive functioning at 2-year follow-up (both p < .01). Optimism was not related to self-reported SPN severity. Significant associations were retained when controlling for demographic/clinical variables, and became non-significant after controlling for depressive and anxiety symptoms. Conclusions Optimism and depressive and anxiety symptoms are associated with HRQoL in CRC patients with chronic (CI)PN. Future research may illuminate the mechanisms that these factors share, like the use of (non)adaptive coping styles such as avoidance and acceptance that may inform the design of targeted interventions to help patients to adapt to chronic (CI)PN.


2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Kristin Zimmermann ◽  
Hadi Mostafaei ◽  
Axel Heidenreich ◽  
Hans U. Schmelz ◽  
Shahrokh F. Shariat ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document