Niosomes: The Current and Future perspectives in Drug Delivery System

Author(s):  
Bhupendra Singh ◽  
Pooja Sharma ◽  
Sujit Bose ◽  
Jyoti Thakur ◽  
Geetanjali Saini ◽  
...  

There are many problems with the conventional dosage form of various drugs and one of them is dosing frequency in which patients have to take the drug again and again throughout the day which is very difficult mainly for the elder patient. So, to overcome this problem the approach of a novel drug delivery system (NDDS) is used to replace the conventional drug delivery system. NDDS mainly deals with sustained release of drugs which is effective to reduce the dosing frequency. Niosome is one of the best approaches of a novel drug delivery system, in which the drug in solution form is enclosed in vesicle which is made up of non-ionic surfactants. In the case of liposome which is another part of NDDS vesicles is made up of phospholipids. Niosome formulation is a powerful tool to resolve the issue of insolubility and the low bioavailability of drugs. This paper overviews the various methods of preparation of Niosome along with its pharmaceutical applications.

2022 ◽  
Vol 24 (1) ◽  
pp. 48-60
Author(s):  
Avani K. Shewale ◽  
◽  
Akshay R. Yadav ◽  
Ashwini S. Jadhav ◽  
◽  
...  

Most common methods of delivery include the preferred topical (skin), transmucosal (nasal, buccal, sublingual, vaginal, ocular and rectal) and inhalation routes. The conventional dosage forms provide drug release immediately and it causes fluctuation of drug level in blood depending upon dosage form. Therefore to maintain the drug concentration within therapeutically effective range needs novel drug delivery system. In the past few decades, considerable attention has been focused on the development of novel drug delivery system (NDDS). The NDDS should ideally fulfill two prerequisites. Firstly, it should deliver the drug at a rate directed by the needs of the body, over the period of treatment. Secondly, it should channel the active entity to the site of action. In conventional drug delivery systems, there is little or no control over release of the drug and effective concentration at the target site can be achieved by irregular administration of grossly excessive doses. At present, no available drug delivery system behaves ideally, but sincere attempts have been made to achieve them through various novel approaches in drug delivery.


2017 ◽  
Vol 14 (3) ◽  
pp. 386-393 ◽  
Author(s):  
Ulya Badilli ◽  
C. Tuba Sengel-Turk ◽  
Gulin Amasya ◽  
Nilufer Tarimci

2020 ◽  
Vol 6 (4) ◽  
pp. 620-622 ◽  
Author(s):  
Dominic C. Grimberg ◽  
Ankeet Shah ◽  
Brant A. Inman

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