scholarly journals HISTORICAL DEVELOPMENT OF THE HYPERBARIC OXYGENATION

2021 ◽  
Vol 27 (2) ◽  
pp. 3772-3777
Author(s):  
Krasimira Tsankova ◽  
◽  
Mila Dimitrova ◽  
Keyword(s):  
Hyperbaric Oxygen ◽  
Hyperbaric Oxygen Therapy ◽  
Historical Development ◽  
Oxygen Therapy ◽  
Hyperbaric Oxygenation ◽  
The Past ◽  
History Of ◽  
Hyperbaric Medicine ◽  
Physical Laws ◽  
Based Medicine

Background: Hyperbaric oxygenation (HBO) is a treatment in which a patient breathes near 100% oxygen within a chamber at a pressure greater than one atmosphere absolute (ATA). The development of hyperbaric medicine is continuous and associated with the history of underwater activities, the development of physical laws and physiological mechanisms of breathing. Purpose: The aim of this article is to present the development of hyperbaric oxygenation internationally and nationally. Materials and Methods: We have conducted a literature review of the published works on hyperbaric oxygen therapy (HBOT) during the last 100 years. Our survey includes scientific reports and books in English and Bulgarian. Results: Three main periods of the historical development of HBOT can be defined. In the past, HBO did not have much scientific support but is extensively used in the field of medicine. We observed an increase in scientific interest in HBO during the last two decades both in our country and worldwide. The majority of the reviewed articles contained information about different aspects of HBO as clinical uses, effects, risks. HBOT has been used as a primary and adjuvant treatment for a variety of diseases for nearly 50 years in Bulgaria. The main areas of application and researches of hyperbaric oxygen therapy include diving diseases, intoxications, traumatic injuries, soft tissue infections, diabetic foot, hearing loss, some neurological disorders, etc. Conclusion: Over the past decades, hyperbaric oxygen therapy has grown rapidly worldwide in accordance with evidence-based medicine methods, and future developments to expand the knowledge are perspective.

scholarly journals The History of Carbon Monoxide Intoxication

Medicina ◽  
2021 ◽  
Vol 57 (5) ◽  
pp. 400
Author(s):  
Ioannis-Fivos Megas ◽  
Justus P. Beier ◽  
Gerrit Grieb
Keyword(s):  
Carbon Monoxide ◽  
Middle Ages ◽  
Hyperbaric Oxygen ◽  
Hyperbaric Oxygen Therapy ◽  
Oxygen Therapy ◽  
Diagnosis And Treatment ◽  
Carbon Monoxide Intoxication ◽  
History Of ◽  
The Middle Ages

Intoxication with carbon monoxide in organisms needing oxygen has probably existed on Earth as long as fire and its smoke. What was observed in antiquity and the Middle Ages, and usually ended fatally, was first successfully treated in the last century. Since then, diagnostics and treatments have undergone exciting developments, in particular specific treatments such as hyperbaric oxygen therapy. In this review, different historic aspects of the etiology, diagnosis and treatment of carbon monoxide intoxication are described and discussed.

scholarly journals Research on the Possibility of Treating Streptococcal Infections with Hyperbaric Oxygenation

2020 ◽  
Vol 70 (1) ◽  
pp. 43-46
Author(s):  
Władysław Wolański
Keyword(s):  
Hyperbaric Oxygen ◽  
Hyperbaric Oxygen Therapy ◽  
Oxygen Therapy ◽  
Hyperbaric Oxygenation ◽  
Lethal Effect ◽  
Streptococcal Infections ◽  
Group A

AbstractThe aim of the study was to determine the effect of the application of hyperbaric oxygen therapy on the course of an infection with group A type T-3 hemolytic β streptococcus. Experiments were carried out on Porton white mice and in vitro blood plates. General and local infections with streptococci were induced in animals. The infected animals were treated with hyperbaric oxygenation. The lethal effect of infection was significantly inhibited using hyperbaric oxygenation on the first and second day following the infection.

scholarly journals Successful Treatment of Lower Limb Complex Regional Pain Syndrome following Three Weeks of Hyperbaric Oxygen Therapy

2016 ◽  
Vol 2016 ◽  
pp. 1-4 ◽  
Author(s):  
Rita Katznelson ◽  
Shira C. Segal ◽  
Hance Clarke
Keyword(s):  
Complex Regional Pain Syndrome ◽  
Hyperbaric Oxygen ◽  
Lower Limb ◽  
Hyperbaric Oxygen Therapy ◽  
Skin Color ◽  
Oxygen Therapy ◽  
Pain Syndrome ◽  
Animal Pain ◽  
History Of ◽  
One Year

Hyperbaric oxygen therapy (HBOT) is a treatment that delivers 100% oxygen at increased atmospheric pressures. The efficacy of HBOT for treating pain has been described in various animal pain models and may have clinical efficacy in the treatment of human chronic pain syndromes. We present our experience with posttraumatic Complex Regional Pain Syndrome (CRPS) type 2 in a patient who underwent 15 sessions of HBOT. A 41-year-old male with one-year history of CRPS of left foot followed by left ankle fracture demonstrated less pain, decreased swelling, less allodynia, and improvement in skin color and range of motion of the lower limb after 3 weeks of HBOT. Patient was back to work for the first time in over a year. HBOT may be considered as a valuable therapeutic tool in the treatment of long-standing CRPS.

scholarly journals Double-blind trials in hyperbaric medicine: A narrative review on past experiences and considerations in designing sham hyperbaric treatment

2018 ◽  
Vol 15 (5) ◽  
pp. 462-476 ◽  
Author(s):  
Nina CA Lansdorp ◽  
Rob A van Hulst
Keyword(s):  
Hyperbaric Oxygen ◽  
Hyperbaric Oxygen Therapy ◽  
Oxygen Therapy ◽  
Lower Pressure ◽  
Controlled Trials ◽  
Double Blind ◽  
Hyperbaric Treatment ◽  
Hyperbaric Medicine ◽  
Oxygen Group ◽  
Blind Trials

Background Hyperbaric oxygen therapy, which consists of breathing 100% oxygen under a higher atmospheric pressure than normal, is utilized worldwide in the treatment of several diseases. With the growing demand for evidence-based research, hyperbaric oxygen therapy has been criticized for delivering too little high-quality research, mainly in the form of randomized controlled trials. While not always indispensable, the addition of a sham-controlled group to such a trial can contribute to the quality of the research. However, the design of a sham (hyperbaric) treatment is associated with several considerations regarding adequate blinding and the use of pressure and oxygen. This narrative review discusses information on the sham profile and the blinding and safety of double-blind trials in hyperbaric medicine, irrespective of the indication for treatment. Methods MEDLINE, Embase and CENTRAL were searched for sham-controlled trials on hyperbaric oxygen therapy. The control treatment was considered sham if patients were blinded to their allocation and treatment took place in a hyperbaric chamber, with no restrictions regarding pressurization, oxygen levels or indication. Studies involving children or only one session of hyperbaric oxygen were excluded. Information on (the choice of) treatment profile, blinding measures, patient’s perception regarding allocation and safety issues was extracted from eligible studies. Results A total of 42 eligible trials were included. The main strategies for sham treatment were (1) use of a lower pressure than that of the hyperbaric oxygen group, while breathing 21% oxygen; (2) use of the same pressure as the hyperbaric oxygen group, while breathing an adjusted percentage of oxygen; and (3) use of the same pressure as the hyperbaric oxygen group, while breathing 21% oxygen. The advantages and disadvantages of each strategy are discussed using the information provided by the trials. Conclusion Based on this review, using a lower pressure than the hyperbaric oxygen group while breathing 21% oxygen best matches the inertness of the placebo. Although studies show that use of a lower pressure does allow adequate blinding, this is associated with more practical issues than with the other strategies. The choice of which sham profile to use requires careful consideration; moreover, to ensure proper performance, a clear and detailed protocol is also required.

scholarly journals Hyperbaric Oxygenation as a Possible Therapy of Choice for Infertility Treatment

2006 ◽  
Vol 6 (2) ◽  
pp. 21-24 ◽  
Author(s):  
Ana Mitrović ◽  
Branka Nikolić ◽  
Svetlana Dragojević ◽  
Predrag Brkić ◽  
Aleksandar Ljubić ◽  
...  
Keyword(s):  
Menstrual Cycle ◽  
Hyperbaric Oxygen ◽  
Hyperbaric Oxygen Therapy ◽  
Oxygen Therapy ◽  
Hyperbaric Oxygenation ◽  
Endometrial Thickness ◽  
Color Doppler ◽  
Endometrial Receptivity ◽  
Doppler Flowmetry ◽  
Randomised Study

Endometrial sonographic and color doppler features can be used to predict the occurrence of pregnancy in natural or stimulated cycles. Implantation will usually only take place if the endometrium has reach a certain stage of vascularisation and development. The aim of this study was to evaluate endometrial development -- endometrial thickness and reflectivity , subendometrial, endometrial and uterine perfusion, after hyperbaric oxygenation, using transvaginal color doppler. During a three years period 32 women with unexplained infertility were entered into a randomised study. The patients were treated in multiplaced HAUX chamber at pressure of 2.3 ATA during 70 minutes, 7 days consecutively beginning with day 5th of menstrual cycle. The evaluation of effects of hyperbaric oxygen therapy was carried out by transvaginal color doppler sonography which was continuously used starting from 8th day of menstrual cycle until the ovulation in the cycles when the therapy was applied , one month before and one month after the therapy. Folliculometry in the cycles when hyperbaric oxygen therapy at 2.3 ATA was applied, indicated an excellent response of endometrium. Thickness of endometrium at the time of ovulation was 11.0 +/- 2.6 mm. Desirable quality of endometrium was significantly better in the cycle when HBO therapy had been applied (p< 0.001). The doppler flowmetry of the uterine arteries indicated that the uterine blood vessel resistance was slightly higher than expected. Mapping of subendometrial blood vessels in the cycles covered by hyperbaric oxygen therapy showed the intensive capillary network of endometrium with low resistance Ri< 0.45. The oxygen used under higher pressure -- oxygen as a drug , may have an extraordinary significance for better outcome of pregnancy implantation by improving endometrial receptivity. If endometrial receptivity is conditioned by adequate vascularisation and oxygenation, then hyperbaric oxygen therapy is the treatment of choice.

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