A rare case of high-grade chondroblastic osteosarcoma post-radiotherapy for a right frontal oligodendroglioma

This is the fourteenth case of an intracranial and dural-based osteosarcoma in the literature to date. The case involves a forty-year old woman with a previous history of a brain tumour, which was treated with surgery, chemotherapy and radiotherapy six years previously. The hypothesis is that this rare malignancy is secondary to the radiation exposure given the growth of the lesion in the previous radiation field

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A very rare case of HPV-53-related cervical cancer, in a 79-year-old woman with a previous history of negative Pap cytology [corrigendum]

Clinical Interventions in Aging ◽

10.2147/cia.s74477 ◽

2014 ◽

pp. 2103

Author(s):

Roberta Zappacosta ◽

Giuseppe Lattanzio ◽

Patrizia Viola ◽

Manuel Maria Ianieri ◽

Daniela Maria Pia Gatta ◽

...

Keyword(s):

Cervical Cancer ◽

Rare Case ◽

Previous History ◽

History Of

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Pancreatic and Hepatic Metastasis of an Undiagnosed Choriocarcinoma: An Exceptional Cause of Haemoperitoneum in Young Women – Report of a Rare Case

Case Reports in Oncology ◽

10.1159/000449462 ◽

2016 ◽

Vol 9 (3) ◽

pp. 633-638 ◽

Cited By ~ 2

Author(s):

Nishat Fatema ◽

Neeru Vinod Arora ◽

Fatma Majid Al Abri ◽

Yaseer Muhammad Tareq Khan

Keyword(s):

Hepatic Metastasis ◽

Rare Case ◽

Previous History ◽

Gestational Trophoblastic Disease ◽

Reproductive Age ◽

Childbearing Age ◽

Women Of Reproductive Age ◽

Positive Pregnancy Test ◽

History Of ◽

The Right

Haemoperitoneum in women of reproductive age usually suggests either ruptured ectopic pregnancy or ruptured ovarian cysts. Metastatic choriocarcinoma is considered the least common cause of haemoperitoneum in women of childbearing age. We report a rare case of pancreatic and hepatic metastasis of choriocarcinoma in a young, 30-year-old female who had delivered 10 months prior at term gestation with no previous history of gestational trophoblastic disease or molar pregnancy. She had a short history of fever and pain in the right hypochondrium, with findings of hypovolaemic shock due to intraperitoneal haemorrhage. Unfortunately, the patient expired with massive uncontrolled bleeding from liver metastasis despite 2 emergency laparotomies within 12 h. This case report is an apt reminder to clinicians to include metastatic choriocarcinoma on the list of differential diagnoses for haemoperitoneum with a positive pregnancy test in women of reproductive age to diagnose early and to avoid life-threatening consequences.

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A case of placenta increta in placenta previa: a rare case report

International Journal of Reproduction Contraception Obstetrics and Gynecology ◽

10.18203/2320-1770.ijrcog20212992 ◽

2021 ◽

Vol 10 (8) ◽

pp. 3245

Author(s):

Badal Das ◽

Debobroto Roy ◽

Malay Sarkar ◽

Krishna Pada Das ◽

Nazmin Khatun ◽

...

Keyword(s):

Rare Case ◽

Placenta Previa ◽

Previous History ◽

Placenta Increta ◽

Decidua Basalis ◽

Adherent Placenta ◽

Rare Case Report ◽

History Of ◽

Scarred Uterus ◽

Caesarean Hysterectomy

Placenta increta, one type of morbidly adherent placenta, is characterized by entire or partial absence of the decidua basalis, and by the incomplete development of the fibrinoid or Nitabuch’s layer and villi actually invading the myometrium. When the internal os is covered partially or completely by placenta, it is described as a placenta previa. Simultaneously these two complications occurring in a post LSCS scarred uterus is a very rare scenario and anticipated frequently to cause catastrophic obstetric outcome. A 32-years-old woman of second gravida, para 1, with previous history of LSCS 7 years back, with living issue one, admitted in our hospital at 35 weeks 5 days gestation with asymptomatic placenta previa with placenta increta. The case was diagnosed effectively by ultrasonography. Intra-operatively, compression sutures and bilateral uterine artery ligature was tried to control hemorrhage which were failed and a quick decision of caesarean hysterectomy was done. Preserving both ovaries, total hysterectomy was the only option to save the mother in our case. Other options attempting to preserve uterus could have ended up with grave consequences in this case. This was a very rare case of asymptomatic placenta previa with placenta increta in a post LSCS scarred uterus and it was successfully managed by judicious caesarean hysterectomy.

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Semi-mobile rudimentary tissues attached to a congenital intramitral ring in a woman with previous history of embolic stroke: A rare case report

Ultrasound ◽

10.1177/1742271x19855103 ◽

2019 ◽

Vol 27 (3) ◽

pp. 191-195

Author(s):

Maryam Nabati ◽

Homa Parsaee ◽

Alireza Fattahian

Keyword(s):

Case Report ◽

Mitral Valve ◽

Rare Case ◽

Previous History ◽

Left Ventricular ◽

Embolic Stroke ◽

Valve Repair ◽

Congenital Cardiac Anomalies ◽

Rare Case Report ◽

History Of

Isolated congenital mitral ring is a very rare subtype of congenital mitral valve malformation, which accounts for about one-third of congenital cardiac anomalies associated with left ventricular inflow obstruction. A mitral ring may be easily missed unless the disease is suspected. The mitral valve repair should be considered in symptomatic patients with mitral stenosis. We report a rare case of a 43-year-old woman with an intramitral ring who experienced previous embolic stroke with left hemiplegia. However, stroke happened several years ago and it does not completely prove causality.

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A rare case of high-grade serous ovarian epithelial carcinoma presenting as an isolated cystic mediastinal mass: a case report and brief review of the literature

Annals of The Royal College of Surgeons of England ◽

10.1308/147870810x12699662980718 ◽

2010 ◽

Vol 92 (5) ◽

pp. e57-e58

Author(s):

Marco Scarci ◽

Rizwan Attia ◽

Tom Routledge ◽

Juliet King

Keyword(s):

Rare Case ◽

Cystic Lesion ◽

Mediastinal Mass ◽

High Grade ◽

Review Of The Literature ◽

Right Thoracotomy ◽

Ovarian Epithelial Carcinoma ◽

History Of ◽

The Right ◽

Primary Presentation

A 70-year-old woman presented with a 2-year history of increasing breathlessness. Computed tomography (CT) of the chest confirmed a well-defined cystic lesion abutting the mediastinum in the right hemi thorax measuring 8 × 6 cm. She underwent a right thoracotomy to excise the cystic lesion. Biopsies for histology demonstrated metastatic serous ovarian epithelial carcinoma. We report a very unusual primary presentation of ovarian epithelial carcinoma as a single cystic mediastinal mass. We also include a brief review of the literature.

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A Contemporary Clinicopathologic Analysis of Primary Urothelial Carcinoma of the Urethra Without Concurrent Renal Pelvic, Ureteral, or Bladder Carcinoma

International Journal of Surgical Pathology ◽

10.1177/10668969211032481 ◽

2021 ◽

pp. 106689692110324

Author(s):

Fengming Chen ◽

Shreyas Joshi ◽

Bradley C. Carthon ◽

Adeboye O. Osunkoya

Keyword(s):

Urothelial Carcinoma ◽

Renal Pelvis ◽

Previous History ◽

Low Grade ◽

High Grade ◽

Divergent Differentiation ◽

History Of ◽

Variant Histology

Primary urothelial carcinoma (UCa) of the urethra is relatively uncommon, and the underlying pathogenesis has not been well characterized, especially in the absence of concurrent UCa at other sites. A search for cases of primary UCa of the urethra was conducted. Patients with concurrent UCa of the renal pelvis, ureter, or bladder at the time of diagnosis of the primary tumor were excluded. Clinicopathologic and follow-up data were obtained. A total of 35 cases from 30 patients (27 male and 3 female) were included in the study. The mean patient age at the initial diagnosis was 71 years (range: 41-90 years). Cases were composed of high-grade UCa (26 of 35 = 74%), low-grade UCa (4 of 35 = 11%), and UCa in situ (5 of 35 = 14%). Invasion was present in 14 of 26 (54%) cases of high-grade UCa. Interestingly, 23 of 30 (77%) patients had a previous history of UCa including 7 (30%) cases with divergent differentiation or variant histology. Follow-up data were available in 23 patients with a mean duration of 26.7 months (range: 0.6-87 months). Eleven patients (31%) died of metastatic UCa. This is one of the largest studies to date of primary UCa of the urethra without concurrent UCa of the renal pelvis, ureter, or bladder. Previous history of UCa of the bladder, especially with divergent differentiation or variant histology is conceivably a key risk factor for developing subsequent primary UCa of the urethra. These findings are important for the development of surveillance protocols and therapeutic strategies.

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A rare case of bacterial infective endocarditis caused by Streptococcus alactolyticus

Heart Vessels and Transplantation ◽

10.24969/hvt.2019.133 ◽

2019 ◽

Vol 3 (Issue 3) ◽

pp. 109

Author(s):

Nedim Cekmen ◽

Oben Baysan ◽

Emine Disbudak ◽

Ceren Gunt

Keyword(s):

Intensive Care Unit ◽

Infective Endocarditis ◽

Aortic Valve ◽

Rare Case ◽

Artery Bypass ◽

Previous History ◽

Blood Cultures ◽

Bypass Grafting ◽

History Of

Background: Streptococcus alactolyticus is a rarely isolated bacterium, which classified under DNA cluster IV of the S. Bovis/S. equinus complex. Infections, especially infective endocarditis, caused by Strep. alactolyticus are very rare in humans. Case Report: We describe a case of Strepotoccocus alactolyticus bacteriemia complicated by infective endocarditis. A 64-year-old male with a previous history of coronary artery bypass grafting applied to our cardiology outpatient clinic with complaints of dyspnea, fever, confusion and an apical holosystolic murmur. He was admitted to the intensive care unit. Transthoracic and transesophageal echocardiography showed the presence vegetation on the aortic valve. S. alactolyticus was detected on serial blood cultures. The patient was first treated with intensive antimicrobial therapy, and then underwent mitral and aortic valve replacements with uneventful follow-up. Conclusion: Streptococcus alactolyticus infective endocarditis has only been reported previously in one patient. More information is certainly needed for diagnosis and treatment of patients infected with Streptococcus alactolyticus. Key words: Streptococcus alactolyticus, endocarditis

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A Rare Shape of Placenta; Placenta Bipartite, Bilobata, Dimidiate, Duplex: A Rare Case Report

Bangladesh Journal of Obstetrics & Gynaecology ◽

10.3329/bjog.v31i2.34220 ◽

2017 ◽

Vol 31 (2) ◽

pp. 101-103

Author(s):

Pratima Rani Biswas ◽

Gautom Kumar Paul ◽

Mina Chowdhury ◽

Md Selim

Keyword(s):

Rare Case ◽

Blood Donors ◽

Previous History ◽

Bed Rest ◽

First Trimester ◽

Lung Maturation ◽

Rare Case Report ◽

History Of ◽

Foetal Movement ◽

Racial Ethnic

Placenta bipartite is a rare variation of placental morphology. The estimated incidence is up to 2-8 % of pregnancy. There is no distinct racial, ethnic or geographical prediction observed. The diagnosis of an anomalous placenta is important for patient management at the time of delivery. Specifically, the bilobed placenta can be associated with first-trimester bleeding, polyhydramnios, abruption, and retained placenta. Careful attention to the cord insertion is also required for optimal fetal management. We report a case of a 24 years multi gravida with previous history of 2 C/S who had regular antenatal checkup and her pregnancy was uneventful till 36 wks. Her early USG at 16 weeks showed low lying placenta little away from the internal os of cervix. She was advised to take complete bed rest, avoid journey and coitus. Couple was warned about pervaginal bleeding, which may occur any time and also advised to ready at least four blood donors. Her 2nd USG scan at 26wks showed placenta bipartite and insertion of cord over the internal os of cervix. Patient was treated conservatively and dose of inj. Oradexon was completed at 32wks for lung maturation. At 36 weeks, patient perceived less foetal movement and then emergency LUCS with BLTL was done. Baby was well and her postpartum period was uneventful.Bangladesh J Obstet Gynaecol, 2016; Vol. 31(2) : 101-103

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Primary Chondroblastic Osteosarcoma of the Breast in a Teenager: What Is Changing?

American Journal of Clinical Pathology ◽

10.1093/ajcp/aqz117.009 ◽

2019 ◽

Vol 152 (Supplement_1) ◽

pp. S88-S89

Author(s):

James Yahaya

Keyword(s):

Triple Negative ◽

Previous History ◽

Phyllodes Tumor ◽

Excisional Biopsy ◽

Left Breast ◽

Treatment Modalities ◽

Large Tumor ◽

Primary Osteosarcoma ◽

History Of ◽

Chondroblastic Osteosarcoma

Abstract Background Nonepithelial tumors of the breast are extremely rare and have an incidence of less than 1%. The most common nonepithelial breast tumor is phyllodes tumor (PT), which accounts for 61%. Primary osteosarcomas of the breast contribute up to only 12.5% of all the extraosseous osteosarcomas, and among young females, they are extremely rare, especially in those without a previous history of primary bone osteosarcoma. A case of a 16-year-old female with primary chondroblastic osteosarcoma of the left breast is herein presented. Case Description In this report, we describe and report a 16-year-old female with neither a previous history of bone osteosarcoma nor a family history of breast cancer who was diagnosed with a primary chondroblastic osteosarcoma of the left breast. The mass was shining, warm, firm, and slightly fixed. The excisional biopsy showed a large tumor measuring 11 × 9 × 7 cm, encapsulated, grayish-white, and nodular. The H&E-stained sections showed a tumor composed of atypical spindle cells, large pleomorphic epithelioid cells, and multinucleated cells of osteoclastic type with osteoid formation with abundant areas having malignant chondroid matrix. About 40 atypical mitoses/10 HPF were seen. A diagnosis of primary osteosarcoma was made. Immunohistochemically, the tumor was triple negative, vimentin was strongly positive, SMA was focally positive, and AE1/AE3 was negative. The patient was put under observation. Her postoperative course is generally promising without any complaint of pain. We present a case of a very young female with the rarest diagnosis of primary osteosarcoma involving the left breast. Conclusion Primary osteosarcomas of the breast carry poor prognosis by being triple negative, and because of being the rarest tumors, they pose a challenge in managing the patients due to lack of established treatment modalities.

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