scholarly journals Fascioliasis: una causa infrecuente de obstrucción de vía biliar. Reporte de un caso

2021 ◽  
Vol 51 (3) ◽  
Author(s):  
Amada Belén Geldres Molina ◽  
Juan Luis Romero García ◽  
Laura Isabel García Honores ◽  
Christian Eduardo Alcántara Figueroa

Hepatic fascioliasis is a parasitic disease caused by the fluke Fasciola hepatica. In the chronic phase of the disease, the adult form of the parasite adopts the bile ducts as the ideal environment to develop, causing them to dilate and simulating an obstructive jaundice process. The case of a 48-year-old woman is presented, who was admitted for jaundice, choluria and eight loss. After the corresponding complementary studies had been carried out, an endoscopic retrograde cholangiography (ERCP) was performed and an adult Fasciola hepatica parasite was extracted from the biliary tract. Subsequently, anthelmintic treatment with triclabendazole was started, resulting in a favorable evolution and resolution of the condition.

Author(s):  
Olival Cirilo Lucena da FONSECA-NETO ◽  
Moacir Cavalcante de ALBUQUERQUE-NETO ◽  
Antonio Lopes de MIRANDA

BACKGROUND: The cystic dilatation of the biliary tract is a rare disease and uncertain origin. It is recognized more frequently in children; however, its incidence comes increasing in adults, representing 20% of the cases. AIM: To evaluate morbimortality rates, evolution and handing of patients with cystic dilatation bile ducts in adults. METHODS: Were evaluated, retrospectively, five adults who had the diagnosis of choledochal cyst and that had been submitted to some surgical procedure. RESULTS: Abdominal pain was the commonest complain to all patients. Jaundice was present in 80%. Ultrasound scanning was done in all the cases as initial examination. CT scan, magnetic resonance imaging and endoscopic retrograde cholangiopancreatography were also done in some patients; however, the diagnosis was established intra-operatively in all cases. The cyst resection with reconstruction of the biliary tract was done in 60%; the cystojejunostomy in 20%; and in 20% biliary tract drainage. CONCLUSIONS: Biliary tract cystic dilatation is a rare disease. However, its incidence is increasing in the adult population, so, it must be thought as differential diagnosis when facing obstructive jaundice.


1978 ◽  
Vol 12 (2) ◽  
pp. 71-72 ◽  
Author(s):  
S. P. Lee

A systematic autopsy study found that 29 of 112 animals had anomalies of the bile ducts. Another rabbit had a septate gallbladder. Awareness of these variants is important during hepatic bile collection, studies involving surgical transplantation or manipulation of the extrahepatic ducts, interpretation of results in experimental cholelithiasis and extrahepatic obstructive jaundice.


1978 ◽  
Vol 15 (6) ◽  
pp. 763-769 ◽  
Author(s):  
R. A. Masake ◽  
R. B. Wescott ◽  
G. R. Spencer ◽  
B. Z. Lang

Primary and secondary infections of F. hepatica in mice were compared to determine how prior exposure to the parasite affected host response. Mice with primary parenchymal Fasciola infections initially had hemorrhagic tunnels filled with inflammatory cells and connective tissue. These lesions were progressive and became most severe 30 days after exposure as the parasites entered the bile ducts. At this time there was much hyperplasia and thickening of all layers of the duct system near the parasites and occasionally severe periportal fibrosis. By 2 months after exposure regeneration of the damaged liver cells was complete although hyperplasia persisted in bile ducts containing flukes. In mice with secondary infections (mice exposed 40 to 50 days after first infection), the inflammatory response was faster and shorter. Most lesions were resolved by 30 days after the second exposure. There was little difference in histology of primary and secondary infections during the chronic phase of the disease.


2020 ◽  
pp. 5-10
Author(s):  
V. V. Boyko ◽  
D. O. Yevtushenko ◽  
I. A. Taraban ◽  
D. V. Minukhin ◽  
A. L. Sochneva

Summary. Introduction. Diseases of the biliary tract can have a malignant, incendiary and traumatic etiology and be accompanied by a syndrome of obstructive jaundice. Objective: to study the effectiveness and specificity of modern technologies for the diagnosis of biliary tract diseases complicated by obstructive jaundice. Materials and research methods. We analyzed the instrumental examination of 118 patients with biliary tract diseases complicated by obstructive jaundice. Results and its discussion. Ultrasound is the first screening test in the diagnosis of biliary tract diseases. Ultrasound was performed in 74 (62.7 %) patients. The sensitivity of ultrasound as an indicator of biliary tract was 74.3 %. In 74.3 % (55 patients), an ultrasound scan was sufficient to make the correct clinical diagnosis. Multispiral computed tomography (MSCT) is an indispensable diagnostic method and method for predicting the volume of surgical intervention for malignant neoplasms of the organs of hepatopancreatic zone. MSCT performed in 59 (50 %) patients. The diagnostic accuracy of MSCT for cholangiocarcinoma of various localization was 91.5 %. Endoscopic examinations were performed in 31 (26.3 %) patients. Endoscopic retrograde cholangio-pancreatography, based on the results of which, if there are indications for further performance, endoscopic papillosphincterotomy, can be considered the method of choice in the diagnosis and stage-by-stage treatment of obstructive jaundice of gallstone etiology. Conclusions. In diseases of the biliary tract, complicated by obstructive jaundice, it is first necessary to perform an ultrasound scan. The highest diagnostic accuracy of ultrasound showed in benign diseases, especially with choledocholithiasis — 94.5 %. In case of insufficient information, MSCT should be used. In the presence of X-ray non-contrast calculi, the use of MSCT is impractical, the sensitivity is 80 %. The highest diagnostic accuracy of MSCT was shown for malignant neoplasms of the urinary tract — 91.5 % and is the method of choice in the diagnosis of the prevalence of tumors and its invasion in adjacent anatomical structures and major vessels.


2018 ◽  
Vol 06 (08) ◽  
pp. E984-E988 ◽  
Author(s):  
Martin Goetz ◽  
Nisar P. Malek

Abstract Introduction The ideal endoscopic retrograde cholangiopancreatography (ERCP) tissue sampling technique should be simple, inexpensive, and yield sufficient tissue for histology while permitting contrast-guided targeting under fluorescence and multiple passes into the bile duct. Current techniques do not fulfill these requirements comprehensively. We designed a catheter for optimized targeting of large intrabiliary biopsies. Methods A 3.5-mm sterile, single-use prototype catheter was developed, with three independent lumina extending continuously to the distal tip for three distinct functions to be available simultaneously: passage of large volume biopsy forceps (1.8 mm), wire guidance (0.035″), and contrast injection. Results First clinical use in five patients (four transpapillary, one percutaneous access) allowed good intrabiliary manipulation in 4/5 patients. Contrast-guided sampling provided adequate specimens. No adverse events were noted. Discussion Technical aspects and preliminary clinical data for the novel triple lumen biopsy catheter are encouraging. The catheter allowed wire guidance and contrast application to guide sampling of larger pieces of tissue. In perspective, the working channel could host any accessory for targeted intrabiliary diagnosis and therapy, and catheter use is not limited to bile ducts.


1996 ◽  
Vol 37 (3P2) ◽  
pp. 685-687 ◽  
Author(s):  
R. Nyman ◽  
H. Al-Suhaibani ◽  
I. Kagevi

The case of a 28-year-old female patient with portal vein thrombosis mimicking tumour and causing obstructive jaundice is presented. The cavernous-transformed enlarged portal vein, explaining the mass-like lesion in the hepatic hilum on ultrasonography, compressed the extrahepatic bile ducts and caused obstructive jaundice. Endoscopic retrograde cholangiography demonstrated multiple nodular extrinsic indentations of the extrahepatic bile ducts with moderately dilated intrahepatic bile ducts.


Author(s):  
Oleksandr Maloshtan ◽  
Rostyslav Smachilo ◽  
Oleksandr Tishchenko ◽  
Аndrii Nekludov ◽  
Мariia Klosova ◽  
...  

Introduction. The problems of the pathogenesis of cholangitis have not been finally clarified to date. Aim: to investigate the dynamics of microbial contamination of the biliary tract in obstructive jaundice before and after decompression. Materials and methods. To determine the significance of the infectious factor in the development of acute cholangitis, bile from the common bile duct was examined in 40 patients with the biliary tract obstruction, which were divided into three groups according to the clinical course of the disease. Results. The quantitative infection indicators of the common bile duct were studied in asymptomatic choledocholithiasis, in obstructive jaundice without clinical manifestations of cholangitis and in a developed clinic of cholangitis. It has been proven that endoscopic decompression of the biliary tree allows to obtain an almost instant therapeutic effect, the number of colony-forming units of the pathogen decreases by almost three orders of magnitude within 3 days. However, in phlegmonous inflammation of the bile duct wall patients, this period was significantly lengthened, and the course of the disease, according to the Tokyo Guidelines (2013), was assessed as severe. Conclusion. In the study of quantitative infection indicators in patients with a bright clinic of cholangitis, a significant decrease in the number of colony-forming units was observed already on the third day after endoscopic papilosphincterotomy due to an adequate drainage effect. When a stone is driven into the large papilla of the duodenum, the common bile duct turns into an analogue of an abscess. Opening the papilla not only frees the mouth of the duct from the stone, but also provides free passage of the contents of the common bile duct (pus) into the duodenum. This provides an almost instant healing effect. When comparing the severity of cholangitis with the histological picture of the wall of the bile ducts (common bile duct, intrahepatic ducts), data were obtained that it is in patients with a severe form of the disease that phlegmonous inflammation of the wall of the duct system takes place. When comparing the severity of cholangitis with the histological picture of the wall of the bile ducts (common bile duct, intrahepatic ducts), data were obtained that phlegmonous inflammation of the wall of the duct system is observed precisely in patients with a severe form of the disease. Keywords: cholangitis, endoscopic decompression


HPB Surgery ◽  
1991 ◽  
Vol 3 (2) ◽  
pp. 129-137 ◽  
Author(s):  
Graham Cullingford ◽  
Brian Davidson ◽  
James Dooley ◽  
Nagy Habib

Biliary tract abnormalities occur in about one of every three people, usually being minor and of no clinical significance.Major abnormalities, however, may present in an unusual manner and provide a major hazard to the unsuspecting surgeon.A patient presenting with cholangitis without jaundice or abnormal liver function tests is reported. Endoscopic retrograde cholangiography failed to demonstrate any bile ducts in the right postero-lateral segments of the liver, the “naked segment sign”. A percutaneous transhepatic cholangiogram demonstrated a stricture obstructing the right posterior segmental hepatic duct with hepatolithiasis above the stricture. At operation an anomalous vessel was found at the site of the stricture.This case highlights the unusual way in which biliary tract anomalies may present and the importance of adequate pre-operative investigation.


2011 ◽  
Vol 152 (47) ◽  
pp. 1907-1910 ◽  
Author(s):  
Krisztina Hagymási ◽  
Zoltán Péter ◽  
Éva Csöregh ◽  
Emese Szabó ◽  
Zsolt Tulassay

Foreign bodies in the biliary tree are rare causes of obstructive jaundice. Food bezoars are infrequent as well. They can cause biliary obstruction after biliary tract interventions, or in the presence of biliary-bowel fistula or duodenum diverticulum. Food bezoars usually pass the gastrointestinal tract without any symptoms, but they can cause abdominal pain and obstructive jaundice in the case of biliary tract obstruction. Endoscopic retrograde cholangio-pancreatography has the major role in the diagnosis and the treatment of the disease. Authors summarize the medical history of a 91-year-old female patient, who developed vomiting and right subcostal pain due to the presence of tomato peel within the ductus choledochus. Orv. Hetil., 2011, 152, 1907–1910.


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