scholarly journals Novel triple lumen catheter for ERCP tissue diagnosis

2018 ◽  
Vol 06 (08) ◽  
pp. E984-E988 ◽  
Author(s):  
Martin Goetz ◽  
Nisar P. Malek

Abstract Introduction The ideal endoscopic retrograde cholangiopancreatography (ERCP) tissue sampling technique should be simple, inexpensive, and yield sufficient tissue for histology while permitting contrast-guided targeting under fluorescence and multiple passes into the bile duct. Current techniques do not fulfill these requirements comprehensively. We designed a catheter for optimized targeting of large intrabiliary biopsies. Methods A 3.5-mm sterile, single-use prototype catheter was developed, with three independent lumina extending continuously to the distal tip for three distinct functions to be available simultaneously: passage of large volume biopsy forceps (1.8 mm), wire guidance (0.035″), and contrast injection. Results First clinical use in five patients (four transpapillary, one percutaneous access) allowed good intrabiliary manipulation in 4/5 patients. Contrast-guided sampling provided adequate specimens. No adverse events were noted. Discussion Technical aspects and preliminary clinical data for the novel triple lumen biopsy catheter are encouraging. The catheter allowed wire guidance and contrast application to guide sampling of larger pieces of tissue. In perspective, the working channel could host any accessory for targeted intrabiliary diagnosis and therapy, and catheter use is not limited to bile ducts.

1997 ◽  
Vol 83 (3) ◽  
pp. 698-702 ◽  
Author(s):  
Vittorio Pugliese ◽  
Giovanna Antonelli ◽  
Maura Vincenti ◽  
Beatrice Gatteschi

Aim and background Pathological proof of malignant in biliary strictures is useful in the preoperative setting as it helps define therapeutic planning and prognosis, and reduces the length of the subsequent surgical intervention. However, it is difficult to obtain. The aim of this study was to evaluate the yield of histological and cytological examination of endobiliary samples obtained during endoscopic retrograde cholangiopancreatography (ERCP). Methods Endobiliary forceps biopsy and brush cytology were performed during ERCP examination in 52 consecutive patients, 36 with malignant and 16 with benign strictures. Results Histology and cytology turned out to have the same sensitivity (53%). The gain in sensitivity achieved by combining the two techniques was limited, reaching a value of 61%. The specificity, however, was 100% for both methods. Most of the few complications observed were due to sphincterotomy and subsided spontaneously or with medical treatment. However, one patient experienced a serious complication and chose to be treated by surgical intervention. The complication was caused by forceps biopsy. Conclusions This study shows that 1) sampling of biliary strictures during ERCP is the primary approach to tissue diagnosis; 2) brush cytology alone is sufficient in clinical practice; 3) forceps biopsy must always be used to sample intra-ampullary strictures but should be considered as a secondary step to sample strictures located more proximally, in the bile ducts, if previous cytology was negative.


2021 ◽  
Vol 51 (3) ◽  
Author(s):  
Amada Belén Geldres Molina ◽  
Juan Luis Romero García ◽  
Laura Isabel García Honores ◽  
Christian Eduardo Alcántara Figueroa

Hepatic fascioliasis is a parasitic disease caused by the fluke Fasciola hepatica. In the chronic phase of the disease, the adult form of the parasite adopts the bile ducts as the ideal environment to develop, causing them to dilate and simulating an obstructive jaundice process. The case of a 48-year-old woman is presented, who was admitted for jaundice, choluria and eight loss. After the corresponding complementary studies had been carried out, an endoscopic retrograde cholangiography (ERCP) was performed and an adult Fasciola hepatica parasite was extracted from the biliary tract. Subsequently, anthelmintic treatment with triclabendazole was started, resulting in a favorable evolution and resolution of the condition.


2011 ◽  
pp. 32-38
Author(s):  
Agata Sadkowska-Fidala

Sixtine by Remy de Gourmont marks the refusal of nature and tangible reality and the choice of imagination to the detriment of reality. Its principal character, Hubert d’Entragues is a faithful disciple of idealism of symbolism. Since he chooses to think rather that to live, it is not surprising that the plot of the novel is almost nonexistent. The plot develops around of d’Entragues’ desire to win the beautiful Sixtine, which is in itself condemned to failure since he is doing nothing to reach her and refuses to take any effort. The woman, who could have served as the principal impulse of the plot, is practically inexistent in this story (though it is a passionate story) and is replaced by the ideal woman: the story is doubled by the second story, e.g. a novel written by the character which is a transposition of his “cerebral” relation with Sixtine and a realisation of presence of the latter. Art replaces life and life does not exist in itself. It is shaped by thought. But the chosen absence of any facts of life is fruitful: it gives birth to a novel. It is a story of a prisoner in love with the statute of the Virgin which he sees while taking a daily walk. In this novel the carnal accomplishment is not necessary in order for a true and sincere passion to develop and the satisfaction of desire may destroy the dream and the ideal.


2019 ◽  
Vol 7 (1) ◽  
pp. 48-54
Author(s):  
Chintia Handayani

This article is based on annotated translation. Annotated translation is a translation with commentary. The objective of this article is to find out strategies that was employed in translating in Personal Pronoun I and You in the novel The Sins of Father by Jeffry Archer. The research used qualitative method with retrospective and introspective as research approached. The syntactic strategies by Chesterman is employ as tools of analysis. The result shows that from 25 data, there are 5 primary data which are taken using purposive sampling technique. There are 3 word ‘I’ and 2 word ‘You’, which all the data has the same translation principle and strategies.


1981 ◽  
Vol 194 (2) ◽  
pp. 171-175 ◽  
Author(s):  
SEIYO IKEDA ◽  
MASAO TANAKA ◽  
HIDEO YOSHIMOTO ◽  
HIDEAKI ITOH ◽  
FUMIO NAKAYAMA

2016 ◽  
Vol 2016 ◽  
pp. 1-5 ◽  
Author(s):  
Tatsuki Ueda ◽  
Masataka Kikuyama ◽  
Yuzo Kodama ◽  
Takafumi Kurokami

Aims. To investigate the effect of biliary stent placement without endoscopic sphincterotomy (EST) on common bile duct stones (CBDS) disappearance and the contribution of preserving the duodenal papilla function to reduce recurrence of CBDS.Methods. Sixty-six patients admitted for acute obstructive cholangitis due to CBDS who underwent biliary stent placement without EST for 2 years from March 2011 were evaluated retrospectively. The second endoscopic retrograde cholangiopancreatography (ERCP) was performed for treatment of CBDS 3 to 4 months after the first ERCP. We estimated the rate of stone disappearance at the time of second ERCP.Results. CBDS disappearance was observed in 32 (48.5%) of 66 patients. The diameter of the bile ducts and the diameter of CBDS in patients with CBDS disappearance were significantly smaller than in those with CBDS requiring extraction (p=0.007andp<0.001, resp.). Stone disappearance was evident when the diameter of bile ducts and that of CBDS were <10 and 7 mm, respectively (p=0.002).Conclusions. Short-term stent placement without EST eliminates CBDS while preserving duodenal papilla function and may be suitable for treating CBDS in patients with nondilated bile ducts and small CBDS.


2021 ◽  
Vol 02 (09) ◽  
pp. 8-14
Author(s):  
Aziza Komilovna Akhmedova ◽  

The article analyzes the results of the research on the representation of the aesthetic ideal through the image of the ideal hero in two national literatures. For research purposes, attention was paid to highlighting the category of the ideal hero as an expression of the author's aesthetic views. In Sinclair Lewis’s “Arrowsmith” and Pirimkul Kodirov's “The Three Roots”, the protagonists artistically reflect the authors' views on truth, virtue, and beauty. In these novels, professional ethics is described as a high noble value. The scientific novelty of the research work includes the following: in the evolution of western and eastern poetic thought, in the context of the novel genre, the skill, common and distinctive aspects of the creation of an ideal hero were revealed by synthesis of effective methods in world science with literary criteria in the history of eastern and western literary studies, in the example of Sinclair Lewis and Pirimkul Kodirov.


Author(s):  
Dhirendra Godara ◽  
Vineet Choudhary ◽  
Nitish Soni

Background: Aims of this study was assess the ideal time of laparoscopic cholecystectomy after endoscopic retrograde cholangiopancreatography in cases of cholelithiasis with Choledocholthiasis Methods: The present study was carried out on 150 patients admitted in Department of General surgery National Institute of Medical Sciences and Research, Jaipur, diagnosed with cholelithiasis along with choledocholithiasis  from 1stJanuary 2019 to 30thJune, 2020. Results: In group 1 out of 75 patients 7 patients developed complications in post operative period compared to 35 patients out of 75 patients developed complications in group 2. The The mean hospital stay (in day) in group 1 patients was 2.26, median 2 and the mean of group 2 was 5.26, median 5. Conclusion: To conclude in our study there has been found significant advantage of early laparoscopic cholecystecomy following ERCP over the late group to minimize complications and promote early recovery of the patients. Keywords: ERCP, Cholecystectomy, Endoscopic retrograde cholangiopancreatography


Author(s):  
Olival Cirilo Lucena da FONSECA-NETO ◽  
Moacir Cavalcante de ALBUQUERQUE-NETO ◽  
Antonio Lopes de MIRANDA

BACKGROUND: The cystic dilatation of the biliary tract is a rare disease and uncertain origin. It is recognized more frequently in children; however, its incidence comes increasing in adults, representing 20% of the cases. AIM: To evaluate morbimortality rates, evolution and handing of patients with cystic dilatation bile ducts in adults. METHODS: Were evaluated, retrospectively, five adults who had the diagnosis of choledochal cyst and that had been submitted to some surgical procedure. RESULTS: Abdominal pain was the commonest complain to all patients. Jaundice was present in 80%. Ultrasound scanning was done in all the cases as initial examination. CT scan, magnetic resonance imaging and endoscopic retrograde cholangiopancreatography were also done in some patients; however, the diagnosis was established intra-operatively in all cases. The cyst resection with reconstruction of the biliary tract was done in 60%; the cystojejunostomy in 20%; and in 20% biliary tract drainage. CONCLUSIONS: Biliary tract cystic dilatation is a rare disease. However, its incidence is increasing in the adult population, so, it must be thought as differential diagnosis when facing obstructive jaundice.


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