Leptospirosis in Si Sa Ket, Thailand: Incidence and Factors of Death during 2010-2019

Disease Surveillance ◽

Public Health Problem ◽

Agricultural Workers ◽

Epidemiological Characteristics

Leptospirosis is an emerging public health problem in Thailand especially Si Sa Ket. The aims of this study were to determine the leptospirosis incidence and factors of death among leptospirosis patients in Si Sa Ket. This study was performed during 2010-2019 from the 506-surveillance report of leptospirosis to the Sisaket Provincial Public Health Office and the National Disease Surveillance System, Bureau of Epidemiology, Ministry of Public Health, Thailand. The data was using the definition of leptospirosis patient for disease surveillance. Multiple logistic regression analysis was performed to evaluate factors of death. A total of 3,988 cases were reported from 22 districts, mainly in rural settings. The incidence rate for leptospirosis was 27.15 per 100,000 population. The dramatic phenomenal of epidemiological characteristics of leptospirosis in Si Sa Ket include a peak incidence in August and October in association with the rainy season. Seventy-four point eight percent of subjects were male, 24.5% were aged 45-54 years and 78.3% were agricultural workers. A total number of 86 deaths were registered in 19 districts. Mortality was higher in males (80.2%). The fatality rate was 2.16%. Significant factors of death found on multiple logistic regression analysis were agricultural workers (Adjusted OR=2.51, 95% CI: 1.15-5.49) and the duration of seeking for medical care >3 days after onset (Adjusted OR=2.45, 95% CI: 1.30-4.61). To reduce the burden disease, the promotion of preventive health behavior, early recognition and treatment of patients have been shown to reduce the severity of illness and death.

PENGARUH KEMAMPUAN IBU HAMIL DALAM MELAKUKAN DETEKSI DINI RISIKO PREEKLAMSIA TERHADAP PARITAS, PENGETAHUAN DAN KETERPAPARAN INFORMASI

Medical Technology and Public Health Journal ◽

10.33086/mtphj.v1i1.275 ◽

2017 ◽

Vol 1 (1) ◽

pp. 27-34

Author(s):

Rr. Galuh Ajeng Indu Dewi

Keyword(s):

Public Health ◽

Logistic Regression ◽

Regression Analysis ◽

Health Center ◽

Maternal Death ◽

Pregnant Mother ◽

Danger Signs

Health conditions, mental status and Life & Style can be lead to complications on Pregnancy can be causing death of mother and fetus (Depkes RI, 2014). The main factor that cause maternal death are postpartum bleeding / HPP (28%), preeclampsia (24%) and infection (11%) (Indonesia Health Profile, 2007). Those factors that cause maternal death actually could be prevented by pregnancy and early detection of the risk of pregnancy check up. The type of this research is analitic observational by using cross sectional design. The population is consist of 171 pregnant mother. The sample used are amount of 62 pregnant mothers. The sample used is probability sampling with stratified random sampling technique. Data collection using primary data with questionnaire instrument through interview. Furthermore, the data would be analyzed with simple logistic regression analysis and multiple logistic regression analysis with the level of meaning 5% (α = 0,05). Based on the results of multiple logistic regression analysis in Sawahan show disclosure information variable of danger signs with significancy Exp value (B) 5,657 are significant variables and variable of paritas with significancy Exp value (B) 9,060 are significant variables. Sawahan Public Health Center is the Public Health Center which has high of Maternal Mortality Rate. Puskesmas Sawahan must have information forum. So that, pregnant mother and the other patient or patient’s family should get more information about the danger signs of pregnancy, especially preeclampsia.

PENGARUH KEMAMPUAN IBU HAMIL DALAM MELAKUKAN DETEKSI DINI RISIKO PREEKLAMSIA TERHADAP PARITAS, PENGETAHUAN DAN KETERPAPARAN INFORMASI

Medical Technology and Public Health Journal ◽

10.33086/mtphj.v1i1.755 ◽

2018 ◽

Vol 1 (1) ◽

pp. 27-34

Author(s):

Rr. Galuh Ajeng Indu Dewi

Keyword(s):

Public Health ◽

Logistic Regression ◽

Regression Analysis ◽

Health Center ◽

Maternal Death ◽

Pregnant Mother ◽

Danger Signs

An Insight on the Use of Multiple Logistic Regression Analysis to Estimate Association between Risk Factor and Disease Occurrence

International Journal of Epidemiology ◽

10.1093/ije/15.1.22 ◽

1986 ◽

Vol 15 (1) ◽

pp. 22-29 ◽

Cited By ~ 34

Author(s):

J. LEE

Keyword(s):

Logistic Regression ◽

Regression Analysis ◽

Risk Factor ◽

Disease Occurrence

P.258 Treatment of nonresponders/relapsers to interferon with peginterferon alpha-2a (40KD) (PEGASYS®) plus ribavirin (COPEGUS®) in routine clinical practice: factors predicting SVR using multiple logistic regression analysis

Journal of Clinical Virology ◽

10.1016/s1386-6532(06)80438-5 ◽

2006 ◽

Vol 36 ◽

pp. S142

Author(s):

M. Sherman ◽

F.H. Anderson ◽

S.V. Feinman ◽

K. Kaita ◽

P. Marotta ◽

...

Keyword(s):

Logistic Regression ◽

Regression Analysis ◽

Clinical Practice ◽

Routine Clinical Practice ◽

Multiple Logistic Regression

Analysis and Factors Associated with Measles in Larut, Matang and Selama Districts, Perak, Malaysia

Malaysian Journal of Medical Sciences ◽

10.21315/mjms2020.27.5.13 ◽

2020 ◽

Vol 27 (5) ◽

pp. 130-140

Author(s):

Asraf Ahmad Qamruddin ◽

Reza Qamruddin ◽

Ayu Malik

Keyword(s):

Logistic Regression ◽

Regression Analysis ◽

Incidence Rate ◽

Protective Factor ◽

Prior History ◽

Case Definitions ◽

Factors Associated

Objectives: To determine the incidence rate of measles and the factors associated with confirmed measles cases in Larut, Matang and Selama districts. Methods: Cross-sectional analysis was carried out looking at all suspected and laboratoryconfirmed measles cases in Larut, Matang and Selama districts between 2015 and 2019. Multiple logistic regression analysis was used to determine the associated factors for laboratory-confirmed measles cases. Results: The incidence rate for suspected measles showed an increasing trend from 2015–2019. For laboratory-confirmed measles cases, the incidence rate showed more variation with an increase to 36.11 per million population in 2017 from 5.67 per million population in 2015. The incidence rate later decreased to 10.99 per million population in 2018 and increased again to 24.47 per million population in 2019. From multiple logistic regression analysis, cases that fulfilled the case definition of measles were more likely to be laboratory-confirmed measles. On the other hand, a prior history of measles immunisation was a protective factor. Conclusion: Measles incidence is increasing in trend. Any suspected measles cases that fulfilled the clinical case definitions need to be further investigated. Immunisation should be promoted as they are effective in preventing and eliminating measles.

Late Acute Kidney Injury is a Poor Prognosis Sign in Severe Burns: A Retrospective Cohort Study

10.21203/rs.3.rs-111856/v1 ◽

2020 ◽

Author(s):

Bo You ◽

Zi Chen Yang ◽

Yu Long Zhang ◽

Yu Chen ◽

Yun Long Shi ◽

...

Keyword(s):

Risk Factors ◽

Logistic Regression ◽

Regression Analysis ◽

Poor Prognosis ◽

Kidney Injury ◽

Occurrence Rate ◽

Severe Burns ◽

Epidemiological Characteristics

Abstract BackgroundAcute kidney injury (AKI) is a morbid complication and the main cause of multiple organ failure and death in severely burned patients. The objective of this study was to explore the epidemiological characteristics, the risk factors, and impact of both early and late AKIs, respectively.MethodsThis retrospective study was performed with prospectively collected data of severely burned patients from the Institute of Burn Research in Southwest Hospital during 2011-2017. AKI was diagnosed according to Kidney Disease Improving Global Outcomes (KDIGO) criteria (2012), and it was divided into early and late AKIs depending on its onset time (within the first 3 days or >3 days post burn). The baseline characteristics, clinical data, and outcomes of the three groups (early AKI, late AKI and non-AKI) were compared using logistic regression analysis. Mortality predictors of patients with AKI were assessed.ResultsA total of 637 patients were included in analysis. The incidence of AKI was 36.9% (early AKI 29.4%, late AKI 10.0%). The mortality of patients with AKI was 32.3% (early AKI 25.7%, late AKI 56.3%), and that of patients without AKI was 2.5%. AKI was independently associated with obviously increased mortality of severely burned patients [early AKI, OR = 12.98 (6.08-27.72); late AKI, OR = 34.02 (15.69-73.75)]. Multiple logistic regression analysis revealed that age, gender, total burn surface area (TBSA), full-thickness burns of TBSA, chronic comorbidities (hypertension or/and diabetes), hypovolemic shock of early burn, and tracheotomy were independent risk factors for both early and late AKIs. However, sepsis was only a risk factor for late AKI. Decompression escharotomy was a protective factor for both AKIs. ConclusionsAKI remains prevalent and is associated with high mortality in severely burned patients. Compared with early AKI, late AKI has a lower occurrence rate, but greater severity and worse prognosis，is a devastating complication. Late AKI is a poor prognosis sign in severe burns.

SAT-564 Effectiveness of Treatment with Mineralocorticoid Receptor Antagonistsin Primary Aldosteronism

Journal of the Endocrine Society ◽

10.1210/jendso/bvaa046.1399 ◽

2020 ◽

Vol 4 (Supplement_1) ◽

Author(s):

Yuta Tezuka ◽

Adina Turcu

Keyword(s):

Logistic Regression ◽

Regression Analysis ◽

Primary Aldosteronism ◽

Odds Ratio ◽

Mineralocorticoid Receptor ◽

Beta Blockers ◽

Low Renin Hypertension

Abstract Background: Medical treatment with mineralocorticoid receptor antagonists (MRAs) is preferred for patients with primary aldosteronism (PA) who are not surgical candidates. Adequate mineralocorticoid receptor blockade, as suggested by renin elevation above suppression levels, has been associated with lower rates of cardiovascular and renal complications as compared with PA with sustained renin suppression. Objectives: To assess the timeline and rates of achieving target renin levels in patients with PA and low renin hypertension treated with MRAs. Patients and Methods: We conducted a retrospective cohort study of adult patients with hypertension who were treated with MRAs in an academic center between 2003-2019. Of these, we included patients who had suppressed renin at baseline, and repeated renin measurement(s) during MRAs therapy. Renin suppression was defined as plasma renin activity (PRA) 1.0 ng/mL/h or direct renin concentration (DRC) 8.0 pg/mL. We excluded patients with adrenal cancer, end-stage renal disease, exogenous glucocorticoids, and critically ill. Mann-Whitney test, Wilcoxon signed rank test, Chi-Square test and multiple logistic regression analysis were employed, as appropriate. Results: So far, 89 patients (45 men), median age 56 (range, 19-84), have been included. Of these, 46% had confirmed PA; 25% had positive PA screening, but no confirmatory tests; and 29% had other forms of low-renin hypertension. On average, patients were on 2.9 1.6 antihypertensive agents; 62% of patients were prescribed beta blockers, and 38% were on K+ supplements. Overall, renin (PRA in 69 cases, and DRC in 20 cases) increased after MRA treatment (from 0.40 [0.10, 0.60] ng/mL/h to 1.10 [0.60, 2.23] ng/mL/h; and from 2.1 [2.1, 3.7] pg/mL to 5.7 [2.9, 16.7] pg/mL, respectively, p<0.0001 for both). The cumulative proportions of patients in whom renin reached target levels during MRA treatment were: 25% at 2 weeks; 38.9% at 1 month; 34.2% at 3 months; 39.5% at 6 months; and 47.2% at 1 year. Age, sex, race, blood pressure, use of beta blockers, renal function, serum K+ and aldosterone concentrations were similar between patients with target vs. suppressed renin. Multiple logistic regression analysis suggested that after adjusting for age and sex, higher MRA dose and higher BMI were associated with higher likelihood of achieving target renin during MRA therapy (odds ratio (95%CI): 1.021 (1.001-1.041) and 1.097 (1.008-1.193), respectively, p<0.05 for both); conversely, beta blockers use tended to be less often associated with target renin (odds ratio, 0.37 (0.13-1.008), p=0.052). Conclusion: Although raising renin above suppression levels is important for reducing the cardiovascular risk associated with PA, this goal is achieved in less than half of patients, even after one year of treatment with MRAs, in an academic setting. Strategies for optimizing PA treatment are critically needed.

Prevalence and Associated Metabolic Factors of Gallstone Disease in the Elderly Agricultural and Fishing Population of Taiwan

Gastroenterology Research and Practice ◽

10.1155/2014/876918 ◽

2014 ◽

Vol 2014 ◽

pp. 1-7 ◽

Cited By ~ 3

Author(s):

Hsi-Che Shen ◽

Yi-Chun Hu ◽

Yu-Fen Chen ◽

Tao-Hsin Tung

Keyword(s):

Logistic Regression ◽

Regression Analysis ◽

Gallstone Disease ◽

Older Age ◽

Metabolic Factors ◽

Female Sex ◽

Study Population

Purpose. To evaluate sex-related differences in the prevalence of and cardiovascular risk factors related to gallstone disease (GSD) in an elderly agricultural and fishing population of Taipei, Taiwan.Methods. The study sample consisted of 6511 healthy elderly participants (3971 men and 2540 women) who were voluntarily admitted to a teaching hospital for a physical checkup in 2010. The participants’ blood samples and real-time ultrasound fatty liver results were collected.Results. The prevalence of GSD in the study population was 13.2%, which increased significantly with population age (P<.0001). Women were associated with significantly higher GSD prevalence than men (14.8% versus 12.2%; for the chi-square test,P=.003). In a multiple logistic regression analysis, female sex, older age, and metabolic syndrome (MetS) were significantly associated with GSD. Multiple logistic regression analysis also revealed that obesity (odds ratioOR=1.26, 95% confidence interval (CI): 1.09–1.44) and metabolic factors (one or 2 versus none,OR=1.48, 95% CI: 1.08–1.76) were significantly associated with GSD in women but not in men.Conclusion. In the study population, female sex, older age, and MetS were associated with higher GSD prevalence. The population exhibited other sex-related differences.

Impact of Oral Health Status on Perceived Dental Problems Among Japan Maritime Self-Defense Force Personnel

Military Medicine ◽

10.1093/milmed/usab216 ◽

2021 ◽

Author(s):

Chikanobu Sonoda ◽

Yutaka Sakurai ◽

Manabu Okoda ◽

Masato Ebisawa ◽

Hiroshi Nakashima ◽

...

Keyword(s):

Logistic Regression ◽

Regression Analysis ◽

Oral Health Status ◽

Oral Disease ◽

Self Defense ◽

Military Mission ◽

Stepwise Procedure

ABSTRACT Introduction Dental problems may have a great impact on military mission effectiveness, as such, evidence-based dental classification guidelines are required for minimizing the occurrence of dental problems. The aim of this study is to elucidate the independent contribution of each oral disease to the perception of dental problems among Japan Maritime Self-Defense Force (JMSDF) personnel in order to make the dental classification guidelines more precise for the prediction of future dental problems. Materials and Methods Japan Maritime Self-Defense Force personnel who were examined during the annual dental checkup in 2013 answered questions about the experience of dental problems within the last 12 months in 2014. The associations between the items of a dental checkup and the perception of dental problems were examined using multiple logistic regression analysis with a stepwise procedure to calculate odds ratios (ORs) and 95% CIs. Results The data of a total of 22,441 subjects were included in the analysis. Those who declared to have perceived dental problems within the last 12 months were 5,088 (22.7%). The multiple logistic regression analysis showed that personnel who had decayed teeth had a higher chance of experiencing dental problems than those who had no dental caries. Personnel whose periodontal disease was judged to be more severe in a dental examination had a greater OR for the perception of dental problems. Conclusion These results may become recommendations for operations in the JMSDF dental classification system.