scholarly journals The Relationship Between Irritable Bowel Syndrome , Depression , Anxiety, and Stress among a Sample of Irritable Bowel Patients - Predictive Study

2016 ◽  
Vol 7 (1) ◽  
Author(s):  
Osama Hasan Gaber

<p>This study aimed to examine the relationship of irritable bowel syndrome, anxiety, depression and stress among a sample of78 IBS patients (Rome III Diagnostic Criteria for Irritable Bowel Syndrome),anxiety symptoms scale ,Depression symptoms scale ,and stress scale (prepared by the researcher) were used Pearson Correlation Coefficient showed that there are statistically significant relationship between IBS and Anxiety ,Depression and Stress (P≤=0.01).The Regression and Prediction Coefficient (stepwise) was also used and showed that the depression and Stress of predicts to IBS.<strong></strong></p>

2019 ◽  
pp. 152-155 ◽  
Author(s):  
G. M. Sakhautdinova ◽  
R. R. Nagaeva ◽  
K. E. Asanbaeva

This article is devoted to the theme of the etiology of irritable bowel syndrome. This topic is highlighted in comparison with the Roman diagnostic criteria of III and IV revision. The following is considered: the theory of disturbed interaction within the «brain-gut» axis and visceral hypersensitivity induced in this way, as well as a possible mechanism for its implementation; also, the relationship of symptoms of IBS with patients’ mental state: anxiety, depression, sleep disorders. The relationship of IBS with microbiota of the intestine, the genetic mediation of IBS, the examples of candidate genes in biomarkers; the mechanisms of work of these genes are also described; the issue of intolerance to certain foods (FODMAPs, IgE-mediated hypersensitivity) in patients with IBS is highlighted as well; immunological aspects, including the theory of subclinical inflammation (low-grade inflammation) or post-infection IBS.


1996 ◽  
Vol 8 (2) ◽  
pp. 81-88 ◽  
Author(s):  
David Kaplan ◽  
Prakash Masand ◽  
Sanjay Gupta

2011 ◽  
Vol 140 (5) ◽  
pp. S-364
Author(s):  
Gregory S. Sayuk ◽  
Christina L. Fales ◽  
C. Prakash Gyawali ◽  
Billy D. Nix ◽  
Yvette I. Sheline

2019 ◽  
Vol 77 (3) ◽  
pp. 161-165
Author(s):  
Zeynep Tugba Ozan ◽  
Nermin Tanik ◽  
Levent Ertugrul Inan

ABSTRACT Tension-type headaches (TTH) and irritable bowel syndrome (IBS) are comorbid diseases affecting, especially, women. One of the underlying mechanisms for both is autonomic dysfunction in the brain-gut axis. We aimed to evaluate the factors accompanying TTH and their relation to functional gastrointestinal disorders. Methods: Women diagnosed with TTH were questioned about headache pattern and severity, and accompanying factors, as well as being screened for IBS according to the Rome III criteria. The participants were divided into two groups: constipation-dominant IBS (IBS-C) group and “others”, with a total of 115 individuals included in the study. Results: Of the 115 patients; 48 (41.8%) of the women had IBS-C criteria while 67 (58.2%) described mixed-type IBS or diarrhea-dominant IBS. There were no significant differences in terms of mean age (p = 0.290), body mass index (p = 0.212), visual analog scale (p = 0.965), duration of attacks (p = 0.692), and episodic/chronic type (p = 0.553). Osmophobia was seen in 43.5%; phonophobia in 68.7%, and photophobia in 47.0% of the patients, and only osmophobia was significantly associated in women in the IBS-C group (p = 0.001). Conclusion: In female patients with TTH, a higher level of constipation was detected. The relationship of these two diseases suggests that they may share common mechanisms. This is the first study showing the relationship of osmophobia with constipation.


2019 ◽  
Vol 28 (4) ◽  
pp. 415-419
Author(s):  
Mihaela Fadgyas Stanculete ◽  
Octavia Capatina ◽  
Cristina Pojoga ◽  
Teodora Surdea Blaga

Background and Aims: Anger has been linked to irritable bowel syndrome (IBS), but the mechanism underlying this relationship is still unknown. This cross-sectional study explores the possibility that anger mediates the relationship between pain severity and depression in IBS patients. Methods: The sample included 70 consecutively evaluated patients who met Rome III criteria for IBS diagnosis and 55 healthy controls. All participants completed measures of depression, pain, state and trait anger, and anger expression style. Results: Using a mediational model involving a series of linear regressions we found that trait anger and anger expression index partially mediated the association between depression and abdominal pain severity. The IBS patients with significant pain reported higher depressive symptoms; these results could be partially explained by their tendency to experience angry feelings generated by pain. Conclusions: The relation between pain and depression is not a direct and linear one, but works partly through patients’ tendency to become angry and through anger expression style regarding their pain.


2018 ◽  
Vol 9 (3) ◽  
pp. 345-355 ◽  
Author(s):  
M.M. Heitkemper ◽  
K.C. Cain ◽  
R.J. Shulman ◽  
R.L. Burr ◽  
C. Ko ◽  
...  

Previously we showed that urine trefoil factor 3 (TFF3) levels were higher in females with irritable bowel syndrome (IBS) compared to non-IBS females. To assess if TFF3 is associated with symptoms and/or reflect alterations in gastrointestinal permeability and gut microbiota in an IBS population, we correlated stool and urine TFF3 levels with IBS symptoms, intestinal permeability, stool microbial diversity and relative abundance of predominant bacterial families and genera. We also tested the relationship of stool TFF3 to urine TFF3, and compared results based on hormone contraception use. Samples were obtained from 93 females meeting Rome III IBS criteria and completing 4-week symptom diaries. TFF3 levels were measured by ELISA. Permeability was assessed with the urine lactulose/mannitol (L/M) ratio. Stool microbiota was assessed using 16S rRNA. Stool TFF3, but not urine TFF3, was associated positively with diarrhoea and loose stool consistency. Higher stool TFF3 was also associated with lower L/M ratio and microbial diversity. Of the 20 most abundant bacterial families Mogibacteriaceae and Christensenellaceae were inversely related to stool TFF3, with only Christensenellaceae remaining significant after multiple comparison adjustment. There were no significant relationships between stool or urine TFF3 levels and other symptoms, nor between stool and urine levels. In premenopausal females, urine TFF3 levels were higher in those reporting hormone contraception. Collectively these results suggest that higher stool TFF3 levels are associated with IBS symptoms (loose/diarrhoeal stools), lower gut permeability, and altered stool bacteria composition (decreased diversity and decreased Christensenellaceae), which further suggests that TFF3 may be an important marker of host-bacteria interaction.


2016 ◽  
Vol 7 (4) ◽  
pp. ar.2016.7.0184 ◽  
Author(s):  
Maria Lauriello ◽  
Alberto Eibenstein ◽  
Anna Maria Angelone ◽  
Marina Pasqua ◽  
Cinzia Tucci ◽  
...  

Background Vasomotor rhinitis (VMR) and irritable bowel syndrome (IBS) are two of the most widespread pathologies in industrialized countries, and they have a substantial impact on health-related quality of life. Objective To investigate the relationship between VMR and IBS to provide evidence to classify VMR and IBS as a sole disorder. Methods The study included 150 patients from San Salvatore Hospital, L'Aquila: 50 with VMR, 50 with IBS, and 50 healthy volunteers. Results With regard to a probable link between VMR and IBS, 62 patients of the whole population, 150 patients (413%) were affected by both VMR and IBS, 33 subjects (22%) were not affected by VMR or IBS, 25 patients (16.67%) only had VMR, and 30 patients (20%) only had IBS. When considering the 87 subjects affected by VMR, 62 of them also had IBS (71.26%). In turn, when considering all 92 subjects with IBS, 62 (67.39%) had VMR. We found a significant association among IBS and nasal obstruction, rhinorrhea, and turbinates, and among VMR and a change in stool consistency and abdominal pain. Among the patients affected by nonallergic rhinitis (NAR), we found a prevalence of NAR with eosinophils (31%) compared with the other cytologic types. Conclusion This study expanded the knowledge of the link between VMR and IBS, also the correlation between typical VMR symptoms and IBS, and about the correlation between typical IBS symptoms and VMR. For future implications, the diagnosis of NAR indicated the need to check for the presence of IBS, by using the Rome III criteria, and a diagnosis of IBS indicated the need to check for the presence of VMR. More studies are needed to find the pathogenetic mechanisms to explain the clinical correlation between VMR and IBS as seen in the present study.


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