scholarly journals Diagnosis-prescription studies – important steps towards a national drug prescription statistics in Norway

2009 ◽  
Vol 11 (1) ◽  
Author(s):  
Jørund Straand

<strong><span style="font-family: TimesNewRomanPS-BoldMT;"><font face="TimesNewRomanPS-BoldMT"><p align="left"> </p></font></span><p align="left"><span style="font-size: x-small; font-family: TimesNewRomanPS-BoldMT;"><span style="font-size: x-small; font-family: TimesNewRomanPS-BoldMT;">ABSTRACT</span></span></p></strong><span style="font-size: x-small; font-family: TimesNewRomanPSMT;"><span style="font-size: x-small; font-family: TimesNewRomanPSMT;"><p align="left">In the first part of this article, drug utilization and prescribing practice is discussed as seen from a</p><p align="left">Norwegian general practice perspective. Which are the data sources available? What kind of studies</p><p align="left">have been performed? Prescription-diagnosis studies are reviewed, in particular the Møre & Romsdal</p><p align="left">Prescription Study (MRPS). Because the wholesales drug statistics do not include information about</p><p align="left">neither patients, prescribers or diagnoses, there is a current need for establishing a more comprehensive</p><p align="left">statistics giving wider and deeper insights into the prescribing and utilization of drugs in the Norwegian</p><p align="left">society. The proposed Norwegian prescription statistics is discussed in relation to previous experiences</p><p align="left">from prescription-diagnosis studies and current needs for research and statistics in the field. Some</p><p align="left">examples are given illustrating why the 11-digit person number probably should be included in the</p><p align="left">database. Lack of diagnostic information may to some extent be compensated for by introducing a more</p><p align="left">differentiated list of diagnoses for the drugs reimbursed. The use of data from this statistics for quality</p><p align="left">assurance in e.g. general practice is discussed. Finally, some suggestions are given for how the Norwegian</p><p>prescription statistics may be organised.</p></span></span>

2009 ◽  
Vol 11 (1) ◽  
Author(s):  
Marit Rønning

<strong><span style="font-family: TimesNewRomanPS-BoldMT;"><font face="TimesNewRomanPS-BoldMT"><p align="left"> </p></font></span><p align="left"><span style="font-size: x-small; font-family: TimesNewRomanPS-BoldMT;"><span style="font-size: x-small; font-family: TimesNewRomanPS-BoldMT;">SUMMARY</span></span></p><p align="left"><span style="font-size: x-small; font-family: TimesNewRomanPS-BoldMT;"></span></p></strong><span style="font-size: x-small; font-family: TimesNewRomanPSMT;"><span style="font-size: x-small; font-family: TimesNewRomanPSMT;">The Anatomical Therapeutic Chemical (ATC) classification system and the defined daily dose (DDD)<p align="left">was developed in Norway in the early seventies. The creation of the ATC/DDD methodology was an</p><p align="left">important basis for presenting drug utilisation statistics in a sensible way. Norway was in 1977 also the</p><p align="left">first country to publish national drug utilisation statistics from wholesalers on an annual basis. The</p><p align="left">combination of these activities in Norway in the seventies made us a pioneer country in the area of drug</p><p align="left">utilisation research. Over the years, the use of the ATC/DDD methodology has gradually increased in</p><p align="left">countries outside Norway. Since 1996, the methodology has been recommended by WHO for use in</p><p align="left">international drug utilisation studies. The WHO Collaborating Centre for Drug Statistics Methodology</p><p align="left">in Oslo handles the maintenance and development of the ATC/DDD system. The Centre is now responsible</p><p align="left">for the global co-ordination. After nearly 30 years of experience with ATC/DDD, the methodology</p><p align="left">has demonstrated its suitability in drug use research. The main challenge in the coming years is to</p><p>educate the users worldwide in how to use the methodology properly.</p></span></span>


2020 ◽  
Author(s):  
Nicole Boffin ◽  
Jerome Antoine ◽  
Luk Van Baelen ◽  
Sarah Moreels ◽  
Kris Doggen

Abstract BackgroundIn Belgium, the incidence of treatment episodes for substance use problems is monitored by the Network of Sentinel General Practices (SGP) and by the Treatment Demand Indicator (TDI) surveillance at higher, specialist care levels. Using both data sources, we examine 1) how patients starting specialist treatment for substance use problems on referral by their GP compare to those that were referred by non-GP caregivers; 2) how patients starting GP treatment for substance use problems without receiving specialist treatment concurrently compare to those who do.MethodsThe same European protocol with common variables was used by both surveillances. Data from 2016 and 2017 were examined using 95% confidence intervals and multivariate regression.ResultsAccording to TDI-data (n=16,543), determinants of being referred by a GP (versus by a non-GP caregiver) for specialist treatment were age ≥ median (OR 1.25; 95% CI 1.13-1.38), education ≥ secondary level (OR 1.27; 95% CI 1.15-1.41), recent employment (OR 1.71; 1.56-1.88), stable housing (3.62; 95% CI 3.08-4.26), first treatment episode (OR 1.72; 95% CI 1.57-1.87), recent daily primary substance use (OR 1.46; 95% CI 1.33-1.59) and mono substance use (OR 1.23; 95% CI 1.04-1.48). Type of substance use was a significant determinant with higher odds of using pharmaceuticals (and alcohol) (OR 1.24; 95% CI 1.04-1.48), and lower odds of using cannabis only/primarily (OR 0.73; 95% CI 0.62-0.86), with reference to street drugs minus cannabis only/primarily. According to SGP data (n=314), determinants of starting GP treatment without concurrent specialist treatment were recent employment (OR 2.58; 95% CI 1.36-4.91), first treatment episode (OR 2.78; 95% CI 1.39-5.55) and living in the Brussels or Walloon region (OR 1.97; 95% CI 1.06-3.66).ConclusionsThis study adds knowledge about the general practice population treated for substance use problems and the consistency of data from the surveillances. Both studies show a relatively favourable profile of general practice patients with substance use problems.


Author(s):  
Zhiyuan Chen ◽  
Aryya Gangopadhyay ◽  
George Karabatis ◽  
Michael McGuire ◽  
Claire Welty

Environmental research and knowledge discovery both require extensive use of data stored in various sources and created in different ways for diverse purposes. We describe a new metadata approach to elicit semantic information from environmental data and implement semantics-based techniques to assist users in integrating, navigating, and mining multiple environmental data sources. Our system contains specifications of various environmental data sources and the relationships that are formed among them. User requests are augmented with semantically related data sources and automatically presented as a visual semantic network. In addition, we present a methodology for data navigation and pattern discovery using multi-resolution browsing and data mining. The data semantics are captured and utilized in terms of their patterns and trends at multiple levels of resolution. We present the efficacy of our methodology through experimental results.


BMJ Open ◽  
2019 ◽  
Vol 9 (4) ◽  
pp. e026076 ◽  
Author(s):  
François Drogou ◽  
Allison Netboute ◽  
Joris Giai ◽  
Xavier Dode ◽  
David Darmon ◽  
...  

ObjectivesOff-label drug prescribing is a public health and economic issue. The aim of this study was to describe off-label prescription in general practice in France, in terms of frequency and nature, and to identify its main determining factors.DesignMulticentre cross-sectional studySettingTwenty-three training general practice officesParticipantsAll the voluntary patients coming for a medical consultation or visited at home over a cumulative period of 5 days per office between November 2015 and January 2016.MethodsEleven interns, acting as observers, collected data. Two reviewers analysed the drugs prescribed by the trainers, in order to identify those prescribed off-label in terms of their indication or the age of the patient. We used a univariate, then a multivariate model, based on hierarchical mixed-effects logistic regression.ResultsAmong the 4932 drug prescriptions registered, 911 (18.5%[95% CI17.4% to 19.6%]) were off-label, of which 865 (17.6%) due to the indication of the drug and 58 (1.2%) due to the age of the patient. The prescription never mentioned the off-label use, neither was the patient informed of it, as required by the French law. With the multivariate analysis, variables contributing to off-label prescription were the number of drugs (OR=1.05 for each additional drug), the initiation of new drug therapy (OR=1.26) and the non-specific goal of the prescription (OR=1.43); the age of the patient ≤14 years (OR=1.42); the rural location of the physician’s practice (OR=1.38) and the low frequency of the visits of national health insurance representatives (OR=0.93).ConclusionAlmost one out of five drugs prescribed in French general practice was off-label. It seems necessary to better train physicians in clinical pharmacology, to provide them with more effective drug prescription software, to reinforce postmarketing surveillance and to clearly define off-label use by consensus.


2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
Thomas Frese ◽  
Henriette Druckrey ◽  
Hagen Sandholzer

Objective. Headache is a common reason for consulting the general practitioner. The goal of the investigation was to characterize the headache consultation rates, the associated symptoms, the frequency of diagnostic and therapeutic procedures, and the results of the encounter of patients with headache. Methods. Cross-sectional data were collected from randomly selected patients during the German SESAM 2 study and compared with unpublished but publicly available data from the Dutch Transition Project. Results. Headache accounts for up to five percent of all general practice consultations. Women consult the general practitioner for headache twice as often as men. Physical examination and drug prescription are the most frequent procedures. Most of the patients suffer from primary headache; secondary headache is due to upper respiratory tract infections or problems of the spinal column. Dangerous courses occur in very rare cases. Conclusion. This work confirms the findings of earlier studies regarding the management of patients that consult the general practitioner for headache. It broadens the preexisting database since cross-sectional data regarding headache in general practice was rarely published.


2016 ◽  
Vol 22 (6) ◽  
pp. 565 ◽  
Author(s):  
Angus Thompson ◽  
Patrick O'Sullivan ◽  
Elisabeth Banham ◽  
Greg Peterson

Prescribing guidelines are an essential component of antimicrobial stewardship programs in Australian hospitals. Nonetheless, the majority of antibiotic prescribing occurs in the community and the effectiveness of guidelines developed specifically to meet the needs of Australian general practice is unknown. This study aims to assess the uptake and effectiveness of a quick reference guide to antibiotic prescribing among primary care prescribers. A quick reference guide to antibiotic prescribing was developed and prescribers in five Tasmanian practices were surveyed regarding use of this guide. Thirty-three surveys were returned and, of those answering specific sections, 75% were aware of the guide and 71% had used it within the last month. The guide affected the antibiotic prescribing practice of 74% of responding prescribers; most often on choice of antibiotic; but also on duration of treatment, dose and dosing frequency. A quick reference guide to antibiotic prescribing was well received by prescribers and may usefully support efforts to improve antimicrobial stewardship in the community.


1990 ◽  
Vol 22 ◽  
pp. 341
Author(s):  
N. Montanaro ◽  
N. Magrini ◽  
A. Vaccheri ◽  
M. Battilana

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