scholarly journals Accuracy of High-Resolution Computed Tomography Chest in Diagnosing Pulmonary Tuberculosis by taking AFB culture findings as Gold Standard

2021 ◽  
Vol 15 (6) ◽  
pp. 1429-1430
Author(s):  
M. Amin ◽  
M. Javed ◽  
A. Noreen ◽  
M. Mehboob ◽  
N. Pasha ◽  
...  
Keyword(s):  
Computed Tomography ◽  
High Resolution ◽  
Pulmonary Tuberculosis ◽  
Gold Standard ◽  
Imaging Modality ◽  
Sufficient Accuracy ◽  
Male Population ◽  
High Resolution Computed Tomography ◽  
Pulmonary Tb ◽  
High Resolution Ct

Aim: To determine the accuracy of high resolution CT Chest (HRCT) for diagnosis of pulmonary tuberculosis (PTB) by taking AFB culture findings as gold standard. Methods: This validation study was conducted in patients referred for HRCT Chest for diagnosis of pulmonary tuberculosis in OPD/ Radiology unit of CH & ICH within duration of 6 months from September-2020 to February -2021. Patients with suspicion of PTB were included. In all patients, sputum samples were obtained and the AFB test was performed for diagnosis of PTB. After that high resolution CT Chest (HRCT) was performed for diagnosis of PTB. Results: Mean age was 54.67 ± 12.36 years. Male population 54% and female was 46%. AFB culture results for pulmonary. TB was positive in 44 patients and was negative in 56 patients. HRCT findings were positive for pulmonary TB in 46 patients and were negative in 54 patients (Table 1). The sensitivity of HRCT was 81.8%, specificity of HRCT was 82.1%, PPV was 78.3% and NPV was 85.2% (Table 2). Conclusion: HRCT Chest has a sufficient accuracy for PTB diagnosis taking AFB culture results as gold standard. So HRCT Chest can be opted as imaging modality of choice in patients having mixed plain radiographs findings. This will aid in early identification and starting treatment of PTB. Keywords: Accuracy, high resolution computed tomography, pulmonary tuberculosis.

Diagnostic Accuracy of High-Resolution Computed Tomography in Assessing Activity of Pulmonary Tuberculosis

2020 ◽  
Vol 11 (4) ◽  
pp. 07-11
Keyword(s):  
Computed Tomography ◽  
High Resolution ◽  
Pulmonary Tuberculosis ◽  
Age Groups ◽  
Clinical History ◽  
Clinical Analysis ◽  
High Resolution Computed Tomography ◽  
Cross Sectional ◽  
Pulmonary Tb ◽  
Suspected Tuberculosis

Background: High-resolution computed tomography (HRCT) has been used in the diagnosis of Pulmonary TB and rapid TB diagnosis is essential and critical for TB control. Objective: To evaluate the role of High-Resolution Computed Tomography in diagnosing and assessing the activity of pulmonary tuberculosis in patients. Methodology: Study Design: Cross-sectional study involving radiographic (HRCT) and clinical analysis of patients with suspected tuberculosis, from October 2018 to March 2019. This study was done on a group of 100 patients with suspected tuberculosis having symptoms of fever, cough with sputum, and hemoptysis. After informed consent first detailed clinical history was taken from patients. Criteria standardized for inclusion was; all age groups and both genders. Patients with a history of previous chest surgery and carcinoma were excluded. Then patients undergoing HRCT chest were analyzed and correlated with clinical findings. Features of primary TB include consolidation, lymphadenopathy, pleural effusion, and miliary nodules whereas post-primary TB include apical consolidation, nodules, and cavitation. Results: Overall 80 (80%) out of 100 subjects were diagnosed with Pulmonary TB on High-Resolution Computed Tomography (HRCT). The most common HRCT findings were tree in bud appearance (77%), fibrotic changes (72%), consolidation (68%), cavitation (40%), bronchiectatic changes (18%), ground-glass haze (18%), and calcified granulomas( 10%). Conclusion: Although chest radiography is the foremost imaging technique in the diagnosis and evaluation of pulmonary tuberculosis in our setup, HRCT can be important in early diagnosis and management with greater sensitivity. Bud appearance and consolidation were the commonest patterns found.

Determination of the Activity of Pulmonary Tuberculosis: the Utility of High-Resolution Computed Tomography

2000 ◽  
Vol 42 (5) ◽  
pp. 757
Author(s):  
Myung Hee Chung ◽  
Hae Giu Lee ◽  
Won Jong Yu ◽  
Hong Jun Chung ◽  
Bo Sung Yang ◽  
...  
Keyword(s):  
Computed Tomography ◽  
High Resolution ◽  
Pulmonary Tuberculosis ◽  
High Resolution Computed Tomography

Diagnostic Accuracy of HRCT Chest in Detection of Covid-19 Infection Taking PCR as Gold Standard

2021 ◽  
Vol 15 (6) ◽  
pp. 1679-1681
Author(s):  
Afaque Ali ◽  
Majid Shaikh ◽  
Ahsanullah . ◽  
Adeel Ahmed ◽  
Abid Ali Sahito ◽  
...  
Keyword(s):  
Computed Tomography ◽  
High Resolution ◽  
Diagnostic Accuracy ◽  
Predictive Value ◽  
Gold Standard ◽  
Cross Sectional Study ◽  
Radiology Department ◽  
High Resolution Computed Tomography ◽  
Cross Sectional ◽  
Head Of Department

Objective: To determine the diagnostic accuracy of High-resolution computed tomography (HRCT) chest in detection of covid-19 infection taking PCR as gold standard. Study Design: Cross-sectional study Setting: Radiology department of Tabba Hospital, Karachi. Duration: From March 2019 to September 2020 Material and Methods: All the clinically suspected patients of covid-19, of any age, both genders and those referred to radiology for High-resolution computed tomography (HRCT) chest to detect the covid-19 infection were included. After two days, patients’ PCR reports were collected from the ward, after taking informed consent and permission from head of department. The diagnostic accuracy of HRCT was established with respect to sensitivity, PPV, NPV, and specificity by taking PCR as gold standard. All the information was collected via study proforma. Results: Total 70 patients suspected for COVID-19 were studied, and the patients’ mean age was 58.23±9.52 years. Males were in majority 54(77.1%). As per HRCT findings, COVID-19 infection was positive in 46 patients, however, 48 patients were detected positive for COVID-19 infection as per PCR findings. In the detection of COVID-19 infection, HRCT chest showed sensitivity of 91%, specificity of 90%, PPV of 83%, NPV of 84% and diagnostic accuracy of 94%; by taking PCR as gold standard. Conclusion: High-resolution computed tomography (HRCT) is a reliable diagnostic approach in promptly detecting the COVID-19; with 91% sensitivity, 90% specificity, 83% positive predictive value, 84% negative predictive value and 94% diagnostic accuracy. Keywords: Accuracy, HRCT, COVID-19

scholarly journals Hypersensitivity Pneumonitis with Normal High Resolution Computed Tomography Scans

2001 ◽  
Vol 8 (2) ◽  
pp. 98-101 ◽  
Author(s):  
Farah J Nasser-Sharif ◽  
Meyer S Balter
Keyword(s):  
Computed Tomography ◽  
High Resolution ◽  
Lupus Erythematosus ◽  
Hypersensitivity Pneumonitis ◽  
Pulmonary Function Tests ◽  
Open Lung Biopsy ◽  
Ct Scans ◽  
High Resolution Computed Tomography ◽  
High Resolution Ct ◽  
History Of

A case of symptomatic hypersensitivity pneumonitis with normal high resolution computed tomography (CT) scans is presented. The patient, a 32-year-old man with systemic lupus erythematosus, had a chronic, progressive history of respiratory symptoms, abnormal findings on examination and abnormal pulmonary function tests but normal high resolution CT scans of the chest. Diagnosis was made through open lung biopsy. Clinical improvement was seen on removal of the offending antigen. The literature on the utility of high resolution CT scans in hypersensitivity pneumonitis is reviewed.

scholarly journals Dual-Energy Computed Tomography Lung in patients of Pulmonary Tuberculosis

2020 ◽  
Vol 10 ◽  
pp. 39
Author(s):  
Ahmad Umar Khan ◽  
Sachin Khanduri ◽  
Zikra Tarin ◽  
Syed Zain Abbas ◽  
Mushahid Husain ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Pulmonary Tuberculosis ◽  
Imaging Techniques ◽  
Ground Glass Opacity ◽  
Signs And Symptoms ◽  
Dual Energy ◽  
Dual Energy Ct ◽  
High Resolution Computed Tomography ◽  
Cross Sectional ◽  
Pulmonary Tb

Objectives: The objective of this study was to characterize findings of high-resolution computed tomography (HRCT) and dual-energy CT (DECT) (80 keV, 140 keV, and mixed) in pulmonary tuberculosis (TB) patients and to compare and correlate HRCT and DECT findings. Material and Methods: This cross-sectional study was conducted on 67 patients of 18–65 years of age who were suspected cases of pulmonary TB with signs and symptoms of cough, fever, hemoptysis, sputum, night sweats, and weight loss with positive sputum AFB examinations/bronchoalveolar lavage. All the patients subjected to HRCT scan and followed with DECT scan. Comparison of various imaging techniques (DECT 80 keV, DECT 140 keV, and DECT mixed) with HRCT was done for detecting lung findings and data so obtained were subjected to statistical analysis. Results: On comparing the various imaging techniques with HRCT for detecting consolidation, tree in bud pattern, cavitary lesions, ground-glass opacity, bronchiectasis, atelectasis, nodules, granuloma, peribronchial thickening, and fibrosis, the maximum agreement of HRCT was found with DECT 80 keV and minimum agreement was found with DECT 140 keV. Conclusion: The study concluded that DECT 80 keV monochromatic reconstructions among 80 keV, mixed, and 140 keV monochromatic reconstructions in lung parenchyma window settings are a faster and better analytical tool for the assessment of findings of pulmonary TB when compared with HRCT.

scholarly journals Tracheal Tube Obstruction in Mechanically Ventilated Patients Assessed by High-resolution Computed Tomography

2014 ◽  
Vol 121 (6) ◽  
pp. 1226-1235 ◽  
Author(s):  
Cristina Mietto ◽  
Riccardo Pinciroli ◽  
Annop Piriyapatsom ◽  
John G. Thomas ◽  
Lynn Bry ◽  
...  
Keyword(s):  
Computed Tomography ◽  
High Resolution ◽  
Tracheal Tube ◽  
Chest Ct ◽  
Ct Scans ◽  
Common Finding ◽  
High Resolution Computed Tomography ◽  
Airflow Resistance ◽  
High Resolution Ct ◽  
Ventilated Patients

Abstract Background: Tracheal intubation compromises mucus clearance and secretions accumulate inside the tracheal tube (TT). The aim of this study was to evaluate with a novel methodology TT luminal obstruction in critically ill patients. Methods: This was a three-phase study: (1) the authors collected 20 TTs at extubation. High-resolution computed tomography (CT) was performed to determine cross-sectional area (CSA) and mucus distribution within the TT; (2) five TTs partially filled with silicone were used to correlate high-resolution CT results and increased airflow resistance; and (3) 20 chest CT scans of intubated patients were reviewed for detection of secretions in ventilated patients’ TT. Results: Postextubation TTs showed a maximum CSA reduction of (mean ± SD) 24.9 ± 3.9% (range 3.3 to 71.2%) after a median intubation of 4.5 (interquartile range 2.5 to 6.5) days. CSA progressively decreased from oral to lung end of used TTs. The luminal volume of air was different between used and new TTs for all internal diameters (P < 0.01 for new vs. used TTs for all studied internal diameters). The relationship between pressure drop and increasing airflow rates was nonlinear and depended on minimum CSA available to ventilation. Weak correlation was found between TT occlusion and days of intubation (R2 = 0.352, P = 0.006). With standard clinical chest CT scans, 6 of 20 TTs showed measurable secretions with a CSA reduction of 24.0 ± 3.9%. Conclusions: TT luminal narrowing is a common finding and correlates with increased airflow resistance. The authors propose high-resolution CT as a novel technique to visualize and quantify secretions collected within the TT lumen.

scholarly journals Use of High-Resolution Computed Tomography (HRCT) in Diagnosis of Sputum Negative Pulmonary Tuberculosis

2016 ◽  
Vol 17 (2) ◽  
pp. 59-64
Author(s):  
Vandna Raghuvanshi ◽  
Ram Gopal Sood ◽  
Anupam Jhobta ◽  
Malay Sarkar ◽  
Ashwani Tomar ◽  
...  
Keyword(s):  
Computed Tomography ◽  
High Resolution ◽  
Pulmonary Tuberculosis ◽  
High Resolution Computed Tomography
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