scholarly journals Tek Doz Olanzapin ile Gelişen Ölümcül Nöroleptik Malign Sendrom: Bir Olgu Sunumu / Single Dose Olanzapin-Induced Fatal Neuroleptic Malignant Syndrome: A Case Report

Author(s):  
Hatice HARMANCI ◽  
Serap ERDOĞAN TAYCAN ◽  
Feryal ÇAM ÇELİKEL ◽  
Hatice KARAER ÜNALDI ◽  
Gülsüm KURT
2019 ◽  
Vol 8 (1) ◽  
Author(s):  
Danielle Levin

We would like to present the first report of severe acute dystonic reaction after a single administration of metoclopramide during cesarean section under combined spinal-epidural anesthesia.  During elective cesarean section, a 30-year-old female vomited four times and was treated with 10mg intravenous metoclopramide and 8mg intravenous ondansetron.  Nausea subsided with the antiemetic treatment, but two minutes later, patient had rapid eye blinking, uncontrollable head movement, and became unresponsive.  Bolus of 50mg intravenous diphenhydramine resolved the acute dystonic symptoms within seconds.  Patient was again oriented times three, with no recollection of symptoms, and remained symptom free for the rest of admission. 


1986 ◽  
Vol 31 (1) ◽  
pp. 66-69 ◽  
Author(s):  
Margaret Schibuk ◽  
Debbie Schachter

The authors present a case report in which an agitated response to antidepressants preceded the neuroleptic malignant syndrome (NMS). In a review of 64 cases of NMS in the literature, they found that 80% were described as agitated prior to the development of the syndrome. Polypharmacy was common. A review of the literature on theories of pathogenesis involving sympathetic amines other than dopamine is presented to explain this phenomena. It is suggested that these toxic reactions to medication can be interpreted as resulting from a relative NE/DA excess, in which antidepressants increase the numerator, while neuroleptics functionally decrease the denominator. It is recommended that where an agitated response to antidepressants is observed, neuroleptics should be used only with considerable caution.


2010 ◽  
Vol 16 ◽  
pp. S13
Author(s):  
A. Gonzalez Ramirez ◽  
V. Mazoteras Muñoz ◽  
J. Martin Marquez ◽  
N. Fernandez Martinez ◽  
G. Martinon Torres ◽  
...  

1970 ◽  
Vol 1 (1) ◽  
pp. 56-58
Author(s):  
SC Kohli ◽  
UK Shrestha ◽  
VM Alurkar ◽  
A Maskey ◽  
M Parajuli ◽  
...  

The global program to eliminate Lymphatic Filariasis created by The World Health organization in 1997 is based on mass administration of single annual doses of diethylcarbamazine ( DEC) plus albendazole in non African regions and of albendazole plus ivermectin in Africa. The usual side effects of DEC treatment include fever, chills, arthralgia, headaches, nausea, and vomiting. Albendazole is associated with relatively few side effects consisting of occasional nausea, vomiting, abdominal pain, headache, reversible alopecia, elevated aminotransferases and rarely leucopenia and rash. We report a case of polyneuropathy in a young individual following DEC and albendazole during mass drug administration. Keywords: Albendazole; DEC; Polyneuropathy. DOI: http://dx.doi.org/10.3126/njms.v1i1.5800   Nepal Journal of Medical Sciences. 2012; 1(1): 56-58


1996 ◽  
Vol 30 (3) ◽  
pp. 419-421 ◽  
Author(s):  
Richard J. Bonwick ◽  
Malcolm J. Hopwood ◽  
Philip L.R Morris

Objective: To describe a case of neuroleptic malignant syndrome associated with risperidone. Clinical picture: An elderly patient with bipolar affective disorder presented with neuroleptic malignant syndrome and relapse of hypomania after commencing risperidone. Treatment: Risperidone was ceased and the patient monitored closely. Outcome: The symptoms of neuroleptic malignant syndrome were resolved. Conclusion: To our knowledge this is the first such case reported, and suggests that risperidone, like other neuroleptics, is associated with neuroleptic malignant syndrome.


2014 ◽  
Vol 18 (3) ◽  
pp. 156-158
Author(s):  
Seher Sayın ◽  
Ruhuşen Kutlu ◽  
Serhat Sayın ◽  
Hüseyin Ataseven

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