scholarly journals Brachial Plexopathy from Metaldehyde Poisoning – A Case Report

2021 ◽  
Vol 26 (4) ◽  
pp. 839-843
Author(s):  
See-Teng Tan ◽  
Guanglin Chen ◽  
Wai Ching, Deanna Lee ◽  
You-Jiang Tan

We describe the case of a middle-aged female with schizophrenia, who developed acute sensorimotor deficits of the right upper limb within a week of ingesting large amounts of metaldehyde in a suicide attempt. A right-sided brachial plexopathy was diagnosed clinically and supported by electrophysiologic assessments and targeted magnetic resonance imaging scans. Although metaldehyde’s neurotoxicity typically affects the central nervous system, focal involvement of the peripheral nervous system remains unreported in medical literature, and its pathogenic processes await further elucidation. Therefore, we recommend the continued observation for the subsequent development of sensorimotor deficits during the first week of metaldehyde poisoning.

2021 ◽  
Vol 13 (1) ◽  
pp. 259-266
Author(s):  
Ye-Tao Zhu ◽  
Yang Liu ◽  
Li-Gang Chen ◽  
Da-Ping Song

Solitary fibrous tumor is a very rare mesenchymal tumor that occurs mostly in the pleura, and there are few reported cases of a presence in the central nervous system, particularly in the cerebellum. In 2016, the WHO classified solitary fibrous tumors into grade I. In this article, we present a case of malignant solitary fibrous tumor recurring 8 years after surgery in a 63-year-old male. Magnetic resonance imaging showed low to intermediate mixed signal intensity on T1W1. Immunohistochemical staining positivity for Vimentin, CD99, CD34 and Bcl-2, it is consistent with the immunohistochemical characteristics of solitary fibrous tumor. We resected the patient’s tumor, and the patient was followed up for 3 months with no signs of recurrence. Solitary fibrous tumors are very rare in the central nervous system. Immunohistochemical staining positivity for CD34 and Bcl-2 is strongly expressed in most solitary fibrous tumor. Surgical resection is the preferred treatment. Due to the small number of cases, the biological behavior and prognosis of this tumor need to be further explored.


2001 ◽  
Vol 69 (10) ◽  
pp. 6545-6548 ◽  
Author(s):  
Jun Fujii ◽  
Yoshimasa Kinoshita ◽  
Takashi Yutsudo ◽  
Hatsumi Taniguchi ◽  
Tom Obrig ◽  
...  

ABSTRACT The action of Shiga toxin (Stx) on the central nervous system was examined in rabbits. Intravenous Stx1 was 44 times more lethal than Stx2 and acted more rapidly than Stx2. However, Stx1 accumulated more slowly in the cerebrospinal fluid than did Stx2. Magnetic resonance imaging demonstrated a predominance of Stx1-dependent lesions in the spinal cord. Pretreatment of the animals with anti-Stx1 antiserum intravenously completely protected against both development of brain lesions and mortality.


2013 ◽  
Vol 13 (4) ◽  
pp. 509-516 ◽  
Author(s):  
Iain D. Wilkinson ◽  
Dinesh Selvarajah ◽  
Marni Greig ◽  
Pallai Shillo ◽  
Elaine Boland ◽  
...  

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