scholarly journals Granular cell tumour of the ureter: first case reported

2013 ◽  
Vol 3 (2) ◽  
pp. 156 ◽  
Author(s):  
Rabii Madi ◽  
Neriman Gokden ◽  
Graham Greene

A 33-year-old woman presented with nonspecific, colicky pain ofthe left lower abdomen. Computed tomography (CT) revealed a2-cm mass engulfing the mid–left ureter. Ureteroscopy and biopsyrevealed normal mucosa, and CT-guided biopsy of the masswas nondiagnostic. The patient underwent laparoscopic exploration.A frozen section taken from the mass revealed a granularcell tumour. We excised the whole involved portion of the ureterand performed end-to-end ureteroureteral anastamosis. The postoperativecourse was uneventful. Examination of a segment ofresected ureter revealed a granular cell tumour diffusely infiltratingthe wall of the ureter. There were no features suggestinga malignant phenotype. On follow-up, the patient was found tohave developed a stricture at the anastomotic area, which wassuccessfully treated with balloon dilatation. To our knowledge,this is the first reported case of a granular cell tumour involvingthe ureter.Une patiente de 33 ans présente des douleurs non spécifiquesau quadrant inférieur gauche de l’abdomen rappelant des coliques.Une TDM révèle une masse de 2 cm englobant la portioncentrale de l’uretère gauche. Une urétéroscopie et une biopsiene révèlent aucune anomalie de la muqueuse, et une biopsiede la masse guidée par TDM n’a pas permis de poser un diagnostic.La patiente a subi un examen par laparoscopie. Des fragmentscongelés de la masse ont révélé une tumeur à cellules granuleuses.Une excision de la partie atteinte de l’uretère a été suivied’une anastomose urétéro-urétérale. Aucune complication postopératoiren’a été signalée. Le rapport final de pathologie faitétat d’une tumeur à cellules granuleuses s’étant infiltrée de façondiffuse dans la paroi de l’uretère. Aucune observation ne porteà croire à la présence d’un phénotype malin. Au suivi, la patienteprésentait une sténose de la région de l’anastomose qu’on a putraiter efficacement par dilatation par ballonnet. À notre connaissance,il s’agit du premier cas de tumeur à cellules granuleusestouchant l’uretère.

Author(s):  
Atheetha R. ◽  
Sankar Sundaram

Congenital granular cell tumour (epulis) is a rare benign tumour occurring in gingiva of neonates, of unknown histogenesis, predominantly occurring in girls. It can cause feeding and respiratory difficulty. We describe a case of a newborn male baby born with swelling in the gingiva of anterior segment of upper jaw. The lesion was excised, with baby doing well at follow up.  


2018 ◽  
Vol 100 (4) ◽  
pp. e85-e87
Author(s):  
A Goetz ◽  
N Nweze ◽  
A Joshi ◽  
J Farma

We describe a unique presentation of a rare disease presentation of a granular cell tumour. A 36-year-old woman presents with a large symptomatic left flank mass that had been slowly increasing in size. Multiple synchronous subcutaneous masses were found at presentation on the left breast, right auricle and right cheek. After diagnosis of granular cell tumour by core needle biopsy, the masses were excised with histopathological and immunohistochemical analysis of both specimens confirming the presence of non-malignant granular cell tumours. Granular cell tumours are rare Schwann cell derived tumours that are typically asymptomatic and benign. These tumours are most often located in the head and neck, with multifocal disease present in approximately 5–16% of patients. Final pathology is necessary for diagnosis and frozen section is rarely helpful. Malignancy is present in approximately 2% of cases and can be diagnosed by the presence of a high mitotic rate, large nucleoli, necrosis, spindling and pleomorphism are other suspicious features. Granular cell tumours do not generally require adjuvant treatment. The mainstay of therapy is surgical resection with surveillance.


2004 ◽  
Vol 44 (5) ◽  
pp. 502-503 ◽  
Author(s):  
I V Prematilleke ◽  
V Sujendran ◽  
B F Warren ◽  
N D Maynard ◽  
J Piris

2007 ◽  
Vol 121 (5) ◽  
pp. 506-509 ◽  
Author(s):  
C Holton ◽  
H E Cruickshank ◽  
A S High ◽  
K Maclennan ◽  
Z G G Makura

Granular cell tumours of the larynx are a very rare cause of persistent hoarse or husky voice in children. We report the case of a 13-year-old girl who presented with a three-year history of progressively huskier voice. We discuss the presentation, location and diagnosis of the tumour. In addition, we present a method of surgical treatment of the tumour, involving the hitherto unreported technique of laser excision and frozen section of the lesion.


2019 ◽  
Vol 22 (3) ◽  
pp. 359-367
Author(s):  
D. Dimov ◽  
T. Dikov ◽  
L. Dimitrova ◽  
C. Filipov ◽  
I. Raychev

The case of a 5-year-old intact female Pitbull Terrier with a granular cell tumour (GCT) of the mammary gland is presented. The dog was admitted for surgical removal of a non-painful lump assumed to be a fibroadenoma. Histological and immunohistochemical findings leading to the diagnosis consisted of polygonal tumour cells with well-defined cell borders and granular cytoplasm, staining positively with neuron-specific enolase (NSE) and protein S100 and negatively for cytokeratin AE1-AE3. Some important points in the diagnostic and therapeutic approach to this uncommon neoplasm are discussed. To our best knowledge this is the first case of such tumour in the mammary gland described in the veterinary literature.


Author(s):  
Uri Manor ◽  
Victoria Doviner ◽  
Jolanta Kolodziejek ◽  
Pia Weidinger ◽  
Amir Dagan ◽  
...  

Capillaria hepatica (syn. Calodium hepaticum) is a parasitic nematode of rodents, rarely infecting humans. An asymptomatic Israeli adult male with extensive travel history was diagnosed with a liver mass on routine post-thymectomy follow-up. Imaging and computer tomography (CT) guided biopsy were inconclusive. Surgical excision revealed an eosinophilic granuloma with fragments of a nematode suspected to be C. hepatica. Molecular methods verified the diagnosis, and the patient was treated empirically. This is the first case of hepatic capillariasis described in Israel, and the first to be diagnosed using molecular methods.


1973 ◽  
Vol 2 (22) ◽  
pp. 1010-1011 ◽  
Author(s):  
Stewart Hart ◽  
Lorna Sisely

2012 ◽  
Vol 24 (7) ◽  
pp. 857-859 ◽  
Author(s):  
Konstantinos Papamichael ◽  
Emmanuel Archavlis ◽  
Constantina Lariou ◽  
Alexia Tsigka ◽  
Gerassimos J. Mantzaris

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