Capillaria hepatica (syn. Calodium hepaticum) as a Cause of Asymptomatic Liver Mass

2021 ◽  
Author(s):  
Uri Manor ◽  
Victoria Doviner ◽  
Jolanta Kolodziejek ◽  
Pia Weidinger ◽  
Amir Dagan ◽  
...  
Keyword(s):  
Eosinophilic Granuloma ◽  
Surgical Excision ◽  
Molecular Methods ◽  
Liver Mass ◽  
Ct Guided ◽  
Capillaria Hepatica ◽  
First Case ◽  
Calodium Hepaticum ◽  
Ct Guided Biopsy

Capillaria hepatica (syn. Calodium hepaticum) is a parasitic nematode of rodents, rarely infecting humans. An asymptomatic Israeli adult male with extensive travel history was diagnosed with a liver mass on routine post-thymectomy follow-up. Imaging and computer tomography (CT) guided biopsy were inconclusive. Surgical excision revealed an eosinophilic granuloma with fragments of a nematode suspected to be C. hepatica. Molecular methods verified the diagnosis, and the patient was treated empirically. This is the first case of hepatic capillariasis described in Israel, and the first to be diagnosed using molecular methods.

scholarly journals Granular cell tumour of the ureter: first case reported

2013 ◽  
Vol 3 (2) ◽  
pp. 156 ◽  
Author(s):  
Rabii Madi ◽  
Neriman Gokden ◽  
Graham Greene
Keyword(s):  
Frozen Section ◽  
Granular Cell ◽  
Normal Mucosa ◽  
Cell Tumour ◽  
Granular Cell Tumour ◽  
Ct Guided ◽  
First Case ◽  
Ct Guided Biopsy ◽  
Colicky Pain

A 33-year-old woman presented with nonspecific, colicky pain ofthe left lower abdomen. Computed tomography (CT) revealed a2-cm mass engulfing the mid–left ureter. Ureteroscopy and biopsyrevealed normal mucosa, and CT-guided biopsy of the masswas nondiagnostic. The patient underwent laparoscopic exploration.A frozen section taken from the mass revealed a granularcell tumour. We excised the whole involved portion of the ureterand performed end-to-end ureteroureteral anastamosis. The postoperativecourse was uneventful. Examination of a segment ofresected ureter revealed a granular cell tumour diffusely infiltratingthe wall of the ureter. There were no features suggestinga malignant phenotype. On follow-up, the patient was found tohave developed a stricture at the anastomotic area, which wassuccessfully treated with balloon dilatation. To our knowledge,this is the first reported case of a granular cell tumour involvingthe ureter.Une patiente de 33 ans présente des douleurs non spécifiquesau quadrant inférieur gauche de l’abdomen rappelant des coliques.Une TDM révèle une masse de 2 cm englobant la portioncentrale de l’uretère gauche. Une urétéroscopie et une biopsiene révèlent aucune anomalie de la muqueuse, et une biopsiede la masse guidée par TDM n’a pas permis de poser un diagnostic.La patiente a subi un examen par laparoscopie. Des fragmentscongelés de la masse ont révélé une tumeur à cellules granuleuses.Une excision de la partie atteinte de l’uretère a été suivied’une anastomose urétéro-urétérale. Aucune complication postopératoiren’a été signalée. Le rapport final de pathologie faitétat d’une tumeur à cellules granuleuses s’étant infiltrée de façondiffuse dans la paroi de l’uretère. Aucune observation ne porteà croire à la présence d’un phénotype malin. Au suivi, la patienteprésentait une sténose de la région de l’anastomose qu’on a putraiter efficacement par dilatation par ballonnet. À notre connaissance,il s’agit du premier cas de tumeur à cellules granuleusestouchant l’uretère.

scholarly journals STUDY OF THE PREVALENCE OF Capillaria hepatica IN HUMANS AND RODENTS IN AN URBAN AREA OF THE CITY OF PORTO VELHO, RONDÔNIA, BRAZIL

2015 ◽  
Vol 57 (1) ◽  
pp. 39-46 ◽  
Author(s):  
Elierson José Gomes da Rocha ◽  
Sérgio de Almeida Basano ◽  
Márcia Maria de Souza ◽  
Eduardo Resende Honda ◽  
Márcio Botelho de Castro ◽  
...  
Keyword(s):  
Urban Area ◽  
Histopathological Examination ◽  
Blood Samples ◽  
Specific Antibodies ◽  
Capillaria Hepatica ◽  
First Case ◽  
Calodium Hepaticum ◽  
True Infection ◽  
The City ◽  
Porto Velho

Introduction: Hepatic capillariosis, caused by Capillaria hepatica (Calodium hepaticum) (Bancroft, 1893), Travassos, 1915 (Nematoda, Trichinelloidea, Capillariidae), is a common zoonosis in rodents but is rare in humans. Seventy-two cases in humans have been reported worldwide since the first case was described by MACARTHUR in 192417,27. This study aimed to determine the prevalence of Capillaria hepatica in humans and rodents in an urban area of Porto Velho, the capital of Rondônia, in Brazil. Methods: After conducting a census of the area, 490 residents were randomly selected, and, after signing a term of consent, provided blood samples that were screened for anti-Capillaria hepatica antibodies. Simultaneously, rats were captured to assess the prevalence of this parasite in rodents by histopathological examination in liver sections. Results: A prevalence of 1.8% was found among residents who had specific antibodies at a dilution of 1:150, indicating exposure to parasite eggs; 0.8% of the subjects also had positive titers at a dilution of 1:400, indicating true infection. The prevalence in rats was 2%. Conclusions: The prevalence of infection with this parasite among humans and rats was low. While the prevalence encountered among humans was within the limits reported in the literature, the prevalence among rodents was much lower.

scholarly journals A Case of Radiation Fibrosis Appearing as Mass-Like Consolidation after SBRT with Elevation of Serum CEA

2010 ◽  
Vol 2010 ◽  
pp. 1-4 ◽  
Author(s):  
Kotaro Terashima ◽  
Yoshiyuki Shioyama ◽  
Satoshi Nomoto ◽  
Saiji Ohga ◽  
Takeshi Nonoshita ◽  
...  
Keyword(s):  
Local Recurrence ◽  
Short Interval ◽  
Primary Lung Cancer ◽  
Dorsal Side ◽  
Ct Guided ◽  
Radiation Fibrosis ◽  
Ct Guided Biopsy ◽  
Serum Cea ◽  
The Right

We report a case of radiation fibrosis appearing as mass-like consolidation, which was difficult to distinguish from local recurrence. A 72-year-old woman was diagnosed as having primary lung cancer (cT1N0M0 stage IA) in the right upper lobe and was treated with SBRT of 48 Gy in 4 fractions. After 12 months, mass-like consolidation appeared around the irradiated area, and after 13 months, it had increased in size. FDG-PET revealed high uptake (SUVmax=5.61) for the consolidation. CT-guided biopsy was performed, but we could not confirm the diagnosis. Considering her poor respiratory function and her age, short-interval follow-up was performed. After 15 months, the consolidation enlarged at the dorsal side, and carcinoembryonic antigen (CEA) became elevated (14.6 ng/mL). Serum KL-6 (436 U/mL) and SP-D (204 ng/mL) were also elevated. However, after 16 months, serum CEA slightly decreased. The consolidation gradually retracted on follow-up CT images. CEA, KL-6, and SP-D were also decreased by degrees. After 40 months, there is no evidence of local recurrence.

scholarly journals Aggressive Vertebral Hemangiomas Causing Compression Fracture with Neurological Deficits: A Retrospective Cohort Study

2020 ◽  
Author(s):  
Hongming Rao ◽  
Guishuang Li ◽  
Limin Liu ◽  
Yuming Huang ◽  
Zhengquan Xu ◽  
...  
Keyword(s):  
Clinical Outcomes ◽  
Body Height ◽  
Compression Fracture ◽  
Neurological Deficits ◽  
Ct Guided ◽  
Guided Biopsy ◽  
Estimated Blood Loss ◽  
Ct Guided Biopsy ◽  
Vertebral Hemangiomas

Abstract Background:In rare instances, aggressive vertebral hemangiomas (VHs) can cause compression fracture, resulting in severe pain and neurological deficits. But the diagnosis and treatment of these aggressive lesions are challenging because of these lesions are rare and atypical. This study aimed to evaluate the safety and efficacy of surgical management for aggressive VHs with vertebral compression fracture by a modified multimodality surgery.Methods:We retrospectively reviewed 6 cases suffering from aggressive VHs with compression fracture and neurological deficits in our department from July 2011 to April 2016. These patients were treated by the multimodality surgery, includingpreoperative embolization, intraoperative injection of gelfoam mixed with cement, and laminectomy decompression.The follow-up period was at least 3 years. Perioperative parameters, clinical outcomes, and radiographical data were collected and analyzed.Results: The 6 patients involved 1 male and 5 females (mean age, 52.3 years).The levels involved were: in thoracic spine (5 cases) and lumbar spine (1 case).Preoperative CT-guided biopsy was conducted in all patients, with 5 patients had definitive pathologic diagnosis. All patients were treated successfully with the multimodal surgery, with no cement leakage and other severe complications. The mean operation time was 182.2 minutes, and the estimated blood loss was 908.3 ml.At an average follow-up of 49.8 months, clinical outcomes assessed by the visual analogue scale and Frankel grade were significantly improved. The vertebral body height and kyphosis angle of the fractured vertebra were also corrected postoperatively. No affected vertebra re-fracture and adjacent vertebral fracture were developed, and none of the patients experienced recurrence of tumor at final follow-up.Conclusions:In cases of aggressive VHs causing compression fracture with neurological deficits, CT-guided biopsy is indicated for the diagnosis. The multimodality surgery (preoperative embolization, intraoperative injection of gelfoam mixed with bone cement combined laminectomy decompression) is effective and safe, and can be considered as an acceptable surgical choice.

scholarly journals Tuberculous Spondylitis of the Craniovertebral Junction

2016 ◽  
Vol 1 (1) ◽  
pp. 31-33 ◽  
Author(s):  
Panayiotis D. Megaloikonomos ◽  
Vasilios Igoumenou ◽  
Thekla Antoniadou ◽  
Andreas F. Mavrogenis ◽  
Konstantinos Soultanis
Keyword(s):  
Craniovertebral Junction ◽  
Tuberculous Spondylitis ◽  
Mycobacterium Tuberculosis Infection ◽  
Halo Vest ◽  
Ct Guided ◽  
Antituberculous Treatment ◽  
Ct Guided Biopsy ◽  
Bony Lesions ◽  
Infection Recurrence

Abstract. Craniovertebral junction tuberculosis is rare, accounting for 0.3 to 1% of all tuberculous spondylitis cases. MR imaging is the modality of choice to detect bone involvement, abscess formation and subligamentous spreading of the pus, to differentiate from other lesions affecting the craniovertebral junction, and to determine the efficacy of treatment. Given the fact that surgical treatment of patients with craniovertebral junction tuberculosis has been associated with a high mortality rate ranging up to 10% and recurrence rate ranging up to 20%, conservative is the standard of treatment for most patients.This article presents a patient with craniovertebral junction Mycobacterium tuberculosis infection diagnosed with CT-guided biopsy. A halo vest was applied and antituberculous treatment with rifampicin, isoniazid and ethambutol was initiated. At 6-month follow-up, the patient was asymptomatic; CT of the cervical spine showed healing of the bony lesions. The halo vest was removed and physical therapy was recommended. Antituberculous treatment was continued for a total of 18 months, without any evidence of infection recurrence

Tonsillar leiomyoma

1987 ◽  
Vol 101 (6) ◽  
pp. 619-623 ◽  
Author(s):  
E. Greenberg ◽  
A. Shupak ◽  
Judith Kelner ◽  
W. S. Meyer
Keyword(s):  
Smooth Muscle ◽  
Spindle Cell ◽  
Correct Diagnosis ◽  
Surgical Excision ◽  
Mitotic Figure ◽  
First Case ◽  
Spindle Cell Tumours ◽  
Benign Leiomyoma ◽  
Histologic Types

AbstractTumors of smooth muscle origin are rare in the oral cavity. To date, only eighty-three cases of oral leiomyomas have been reported. A first case of tonsillar leiomyoma in a 73-year-old male is presented. The theories of origin and the various histologic types of oral leiomyomas are discussed. Leiomyoma can easily be confused with other spindle-cell tumours. Special stains are necessary to reach a correct diagnosis. It is sometimes difficult to differentiate benign leiomyoma from malignant leiomyosarcoma. The use of mitotic figure count to indicate malignant behaviour is not always reliable. The need for wide surgical excision of the tumour, complete sectioning and examination of the specimen and meticulous follow-up of the patient for evidence of recurrence are emphasized.

scholarly journals Hematopoietic Islands Mimicking Osteoblastic Metastases in Axial Skeleton

2021 ◽  
Author(s):  
Sophia Samira Goller ◽  
Bernd Erber ◽  
Nicola Fink ◽  
Hans Roland Dürr ◽  
Thomas Knösel ◽  
...  
Keyword(s):  
Correct Diagnosis ◽  
Axial Skeleton ◽  
Appendicular Skeleton ◽  
Imaging Findings ◽  
Ct Guided ◽  
Additional Information ◽  
Ct Guided Biopsy ◽  
Characteristic Imaging ◽  
Important Additional Information

Abstract Background. Hyperplasia of the hematopoietic bone marrow in the appendicular skeleton is common. Focal hematopoietic islands within the axial skeleton is a rare entity and can cause confusion with osteoblastic metastases. The purpose of this study was to describe the characteristic imaging findings in MRI and CT.Methods. We retrospectively analyzed the imaging findings of 14 hematopoietic islands of the axial skeleton in ten patients (nine females, median age= 65.5 years [range, 49-74]), who received both CT and MRI at the time of initial diagnosis between 2006 and 2020. In five cases CT-guided biopsy was performed to confirm the diagnosis, while the other five patients received long term MRI follow-up (median follow-up= 28 months [range, 6-96 months]). Diffusion-weighted imaging was available in three, chemical shift imaging in two, 18F fluorodeoxyglucose PET/CT in two and Technetium 99m skeletal scintigraphy in one of the patients.Results. All lesions were small (mean size=1.72 cm2) and showed moderate hypointense signals on T1- and T2-weighted MRI sequences. They appeared iso- to slightly hyperintense on STIR images and showed slight enhancement after gadolinium administration. To differentiate this entity from osteoblastic metastases, CT provides important additional information, as hematopoietic islands do not show sclerosis. Conclusions. Hematopoietic islands within the axial skeleton can occur and mimic osteoblastic metastases. However, the combination of MRI and CT allows for making the correct diagnosis.

scholarly journals Pediatric Extraspinal Sacrococcygeal Ependymoma: Report of Two Cases and Literature Review

Diagnostics ◽  
2021 ◽  
Vol 11 (9) ◽  
pp. 1680
Author(s):  
Francesco Fabozzi ◽  
Silvia Ceccanti ◽  
Antonella Cacchione ◽  
Giovanna Stefania Colafati ◽  
Andrea Carai ◽  
...  
Keyword(s):  
Literature Review ◽  
Case Reports ◽  
Case Series ◽  
Surgical Excision ◽  
Central Canal ◽  
Ependymal Cells ◽  
The Past ◽  
First Case ◽  
One Year

Primary central nervous system (CNS) tumors represent the most common solid tumors in childhood. Ependymomas arise from ependymal cells lining the wall of ventricles or central canal of spinal cord and their occurrence outside the CNS is extremely rare, published in the literature as case reports or small case series. We present two cases of extra-CNS myxopapillary ependymomas treated at our institution in the past three years; both cases originate in the sacrococcygeal region and were initially misdiagnosed as epidermoid cyst and germ cell tumor, respectively. The first case, which arose in a 9-year-old girl, was treated with a surgical excision in two stages, due to the non-radical manner of the first operation; no recurrence was observed after two years of follow-up. The other case was a 12-year-old boy who was treated with a complete resection and showed no evidence of recurrence at one-year follow-up. In this paper, we report our experience in treating an extremely rare disease that lacks a standardized approach to diagnosis, treatment and follow-up; in addition, we perform a literature review of the past 35 years.

scholarly journals Giant Cell Reparative Granuloma of the Orbit: Clinicopathological Characteristics and Treatment

2021 ◽  
Vol 2021 ◽  
pp. 1-7
Author(s):  
Álvaro Bengoa-González ◽  
Enrique Mencía-Gutiérrez ◽  
Beatriz Alonso-Martín ◽  
Bianca-Maria Laslău ◽  
Elena Salvador ◽  
...  
Keyword(s):  
Giant Cell ◽  
Surgical Excision ◽  
Clinicopathological Characteristics ◽  
Giant Cell Reparative Granuloma ◽  
First Case ◽  
Complete Surgical Excision ◽  
Cranial Fossa ◽  
Histopathologic Analysis ◽  
Fluid Levels

Giant cell reparative granuloma (GCRG) is a rare fibroosseous lesion uncommonly seen in the orbital area. Although benign, it is known to be recurrent and locally destructive. We report two cases of GCRG of the orbit. In both cases, computed tomography revealed a heterogeneously growing well-defined mass, arising from the roof of the orbit, affecting the cortex, and invading the orbit. In the first case, the mass extended into the anterior cranial fossa. Magnetic resonance imaging with gadolinium showed, in both cases, a cystic character of the lesion with fluid levels. The surgical treatment was performed via an upper crease incision. An ultrasonic aspirator system was used to remove the tumor tissue and its extension into cranial fossa. Careful histopathologic analysis established the diagnosis of GCRG. Symptoms resolved completely with no evidence of recurrence after a follow-up of 18 and 14 months, respectively. We present the clinicopathological and radiological findings, and we describe the surgical approach. As a rare entity, GCRG of the orbit should be considered in differential diagnosis of fibroosseous orbital masses. Complete surgical excision carries a low risk of recurrence.

scholarly journals Neuro-radiology: a new gold standard investigation for management of central nervous system tuberculosis

2016 ◽  
Vol 4 (1) ◽  
pp. 14
Author(s):  
Vinod Gautam
Keyword(s):  
Drug Sensitivity ◽  
Therapeutic Interventions ◽  
Drug Resistant ◽  
Biochemical Tests ◽  
Sensitivity Testing ◽  
Radiological Investigation ◽  
Ct Guided ◽  
Ct Guided Biopsy

<p>Treatment of CNS TB is challenging due to lack of specific biochemical tests and inability to get the pathological sample from deeply located eloquent areas of CNS without causing any neurological deficit. Moreover, it is unnecessary to operate for biopsy in a patient who has presented with a very small granulomatious lesion in brain or spinal cord. In such as situations neuro-radiology helps in managing CNS TB and it may be the only source of establishing diagnosis and evaluating treatment response.</p><p>Role of radiological investigation has expanded from the initial diagnosis to the therapeutic interventions. In some Muli-drug- resistant (MDR) CNS TB cases, Stereotaxy or USG or CT guided biopsy helps in obtaining pathological sample and drug sensitivity testing. A regular clinical and neuro-radiological follow-up is mandatory during the entire course of anti tuberculous therapy to take prompt decisions to change ATT and to reduce morbidity and mortality associated with CNS TB.</p>

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