scholarly journals A case report of retroperitoneal Castleman disease

2013 ◽  
Vol 3 (3) ◽  
pp. 14 ◽  
Author(s):  
Peng Bo ◽  
Zheng Junhua ◽  
Gao Qiruo ◽  
Li Hong

Castleman disease (CD) is an uncommon lymphoproliferative disorderand is especially rare in the retroperitoneum or perirenalarea. We report the case of a 42-year-old woman in whom we foundon routine physical examination a mass localized in the rightabdomen without clinically important constitutional symptoms for30 days. Abdominal ultrasound, magnetic resonance images andcomputed tomography scans revealed a solid mass localized justbelow the right kidney in the retroperitoneum. The patient subsequentlyunderwent an exploratory laparotomy. Pathological examinationrevealed a right retroperitoneal mass of CD (hyaline vasculartype). The patient completely recovered after surgery. Castlemandisease is commonly misdiagnosed as malignant lymphoma,lymphadenitis or ectopic thymoma. So far, its diagnosis is mainlyachieved via histopathological examination of surgically obtainedtissue. After removal of the lesion, local CD has a good prognosis.La maladie de Castleman est un trouble lymphoprolifératif rare,surtout dans les régions rétropéritonéale ou périrénale. Nousdécrivons le cas d'une femme de 42 ans chez qui un examenphysique de routine a révélé la présence d'une masse localiséeau côté droit de l'abdomen sans que cette patiente n'affiche desymptômes constitutionnels d'importance clinique pendant 30 jours.Des images obtenues par échographie abdominale, par IRM et partomodensitométrie ont révélé la présence d'une masse solide situéejuste en dessous du rein droit dans la région rétropéritonéale. Lapatiente a ensuite subi une laparotomie exploratoire. L'examend'histopathologie a révélé une masse rétropéritonéale droite caractéristiquede la maladie de Castleman dans sa forme hyaline vasculaire.La patiente s'est complètement rétablie après l'intervention.Au moment du diagnostic, la maladie de Castleman est souventconfondue avec un lymphome malin, une lymphadénite ou un thymomeectopique. Jusqu'à présent, le diagnostic de cette maladieest posé principalement sur la base d'un examen histopathologiquede tissus prélevés par chirurgie. Après ablation de la masse, lepronostic lié à la maladie de Castleman est favorable.

2015 ◽  
Vol 23 (2) ◽  
pp. 256-258
Author(s):  
Mafruha Akter ◽  
Ibrahim Khalil ◽  
Golam Nabi ◽  
Syed Zakir Hossain ◽  
Md Uzzwal Mallik ◽  
...  

Castleman disease (CD) or angiofollicular lymph node hyperplasia is an uncommon benign lymphoproliferative disorder. Sometimes it is related to the chronic human herpes virus 8 (HHV-8) infection and the human immunodeficiency virus (HIV). Two clinical entities have been described: a unicentric presentation with the disease confined to a single anatomic lymph node and a multicentric presentation characterized by generalized lymphadenopathy and a more aggressive clinical course. Also, three histopathological subtypes have been described: hyalinevascular, plasma cell, and a mixed variant.We report the case of a 22-year-old young man who was diagnosed as unicentric Castleman Disease. We found on routine physical examination a mass localized in the left abdomen without clinically important constitutional symptoms for 3 years. Abdominal ultrasound and computed tomography scans revealed minimally enhancing soft tissue density lesion & it was seen in the left para aortic region measuring about 71mm x 42 mm in size. The patient subse-quently underwent an exploratory laparotomy. After opening of the abdomen, a lump measuring about 8 cm x 5 cm was found in the mesentery. The whole lump was dissected out and the gap in the mesentery was closed. No other lymphadenopathy was found. The specimen was sent for histopathology which revealed Castleman disease, plasma cell type. The patient completely recovered after surgery. Castleman disease is commonly misdiagnosed as malignant lymphoma, lymphadenitis or ectopic thymoma. So far, its diagnosis is mainly achieved via histopathological examination of surgically obtained tissue. Local or unicentric CD has a good prognosis if surgically excised properly.J Dhaka Medical College, Vol. 23, No.2, October, 2014, Page 256-258


2020 ◽  
Vol 8 (2) ◽  
pp. e001012
Author(s):  
Luis Pedro Rocha Moreira ◽  
Emma Scurrell ◽  
Paul Mahoney ◽  
Stephen Baines

Canine thyroid tumours are uncommon and the majority of tumours are carcinomas or adenomas, with only very few mixed tumours or metastases from distant sites described to date. A primary thyroid haemangiosarcoma has never been reported in veterinary medicine. In this case report, we describe a dog with a history of a large, non-painful, mobile ventral neck mass in the right paralaryngeal region. CT and ultrasound-guided fine needle aspirates were used for clinical staging. The mass was surgically excised and histopathological examination indicated a haemangiosarcoma. Abdominal ultrasound revealed the presence of splenic nodules and splenectomy indicated the presence of haemangiosarcoma. Chemotherapy with doxorubicin was started, but the dog was euthanased after three rounds of therapy, 97 days after the mass was discovered.


2018 ◽  
Vol 159 (19) ◽  
pp. 768-772
Author(s):  
Tamás Vass ◽  
Attila Zaránd ◽  
Dániel Horányi ◽  
László Harsányi

Abstract: Diverticulitis of the vermiform appendix is a rare disease with clinical features often similar to conventional acute appendicitis. The importance of appendiceal diverticulosis is the fact that it can lead to an early and a higher incidence of perforation and therefore a higher mortality rate, in contrast to acute appendicitis alone. In this study we present the clinicopathology, diagnosis and therapy of the disease with a review of the literature. A 65-year-old woman presented to the emergency department with a 48-hour history of intermittent pain in the right iliac fossa. Abdominal ultrasound raised the possibility of acute appendicitis but because of the relative asymptomatic state of the patient, the lack of fever and rebound tenderness we started observation. After 2 days with episodic abdominal pain, the patient was taken to the operating theatre for laparoscopic exploration. Intraoperatively, multiple diverticula were noted on the appendix and appendectomy was performed. Histopathological examination revealed diverticulosis and inflammation of the appendiceal wall. Due to the possible complications, the difficult preoperative diagnosis and its frequent association with appendiceal neoplasm, appendiceal diverticulosis requires special attention. For asymptomatic cases, incidentally diagnosed intraoperatively or discovered by radiology prophylactic appendectomy is recommended. Orv Hetil. 2018; 159(19): 768–772.


2021 ◽  
Vol 15 (7) ◽  
pp. 1449-1449
Author(s):  
M. Hajri ◽  
W. Ferjaoui ◽  
S. Baccouche ◽  
L. Gharbi ◽  
H. Mestiri ◽  
...  

A 55-year-old woman, with no medical history, presented with acute right flank pain. She had no history of other urinary complaints. On physical examination, the patient was tachycardic (pulse rate: 100bpm) and tachypneic (respiratory rate: 24 breaths/min), blood pressure was11/6 and temperature was 37.4°. The abdominal examination showed severe tenderness in the right flank and the right iliac fossa. All blood reports were normal, including C-reactive protein, cell blood count and serum creatinine. Computed Tomography of the abdomen revealed a right hydronephrosis with delayed phase contrast leak and a retroperitoneal mass of 48x36mm of unknown nature, enhanced after contrast injection, which seemed to compress the right ureter causing the forniceal rupture. A double J ureteral stent was insterted into the right renal cavities with favorable evolution and immediate resolution of pain. Surgical management of the mass was scheduled one month later after the inflammatory phase and resorption of the urinoma. The patient underwent an exploratory laparotomy. Intraoperatively, a tissular retroperitoneal mass of 4 cm was discovered which invadedthe right proximal ureter as well asthe duodenum and the ileocecal pedicle (Figure 1). Resection of the tumor was performed as well as a segmental ureterectomy, right colectomy, and resection of a small portion of the duodenum. Both ureteric and colic anastomosis were then performed along with duodenal suture. The post operative course was uneventful.


2018 ◽  
Vol XXIII (132) ◽  
pp. 56-64
Author(s):  
Sayonara da Luz Ferro ◽  
Ewerton Cardoso ◽  
Fernanda Jönck ◽  
Marta Cristina Thomas Heckler ◽  
Bruna Warmlin ◽  
...  

Hemangioma is a benign, noninvasive and non-metastatic neoplasm originating from endothelial cells of the blood vessels. The involvement of the urinary vesicle with neoplasias occurs in less than 0.5% of dogs. The main clinical signs are hematuria, dysuria, pollakiuria, incontinence and urinary obstruction. The diagnosis is based on imaging tests and is confirmed by histopathological examination. The treatment of choice is surgical resection with safety margins. This paper reports the case of a twelve-year-old Poodle with a history of abdominal pain, which was attended at the Florianópolis Veterinary Hospital. Abdominal ultrasound showed the presence of free fluid. During exploratory laparotomy, the urinary vesicle was observed to be ruptured, presenting a thickened wall and small areas of necrosis. A sample was sent for histopathological analysis and the diagnosis was of benign vascular neoplasia compatible with hemangioma.


2009 ◽  
Vol 11 (8) ◽  
pp. 701-705 ◽  
Author(s):  
Mellora J. Sharman ◽  
Clara S. Goh ◽  
Richard G. Kuipers von Lande ◽  
Jennifer L. Hodgson

A 5-year-old, female Ragdoll cat was diagnosed with an intra-abdominal mycetoma involving the ileocaecal region. Diagnosis was obtained via histopathological examination following surgical resection of the mass and an ileocolic anastomosis. The initial surgery was complicated by lymphangiectasia, chylous abdominal effusion and mild bacterial leakage from the anastomosis site. A second, exploratory laparotomy was performed to augment the anastomosis with serosal patching and omentalisation and to investigate a cystic structure observed on follow-up abdominal ultrasound. Initial amoxycillin clavulanate (Clavulox; Pfizer Animal Health) therapy was ineffective, but clindamycin (Antirobe; Pfizer Animal Health) proved successful in resolving the infection. Abdominal actinomycetoma in the cat may be an under-diagnosed condition due to its close resemblance to neoplastic disease. Standard diagnostic and therapeutic regimens are commonly ineffective in Actinomyces species infections. Surgical resection along with adjunctive, long-term, selective antimicrobial therapy is effective and prognosis is good for localised lesions.


Mediscope ◽  
2020 ◽  
Vol 7 (1) ◽  
pp. 58-62
Author(s):  
Ashish Kumar Chowdhury ◽  
Jashim Uddin Ahmed ◽  
Mowsumi Chowdhury ◽  
Satyam Sarker

Carcinoid of the pancreas is rare among children. We treated a debilitating child who complained about post-prandial pain with a mass in upper abdomen, vomiting and weakness for a period of six months. Abdominal examination revealed an immobile, mildly tender, solid mass in the right lumbar region. Ultrasonography of abdomen demonstrated a tumour of head of the pancreas and ultrasonography-guided fine needle aspiration cytology of the mass suggested a malignant small round cell tumour. With Computed Tomogram an enhancing compact big mass was found at the head of the pancreas compressing the duodenum without invasion and metastasis. At exploratory laparotomy, we also detected a well-defined, rounded, big solid mass arising from uncinate process of the pancreas with no metastasis. After the excision of the mass along with a healthy portion of uncinate process, the patient recovered successfully. Histopathology evaluation showed a neoplasm composed of small nests and sheets of a dense cluster of malignant round cells with hyperchromatic nuclei, sometimes forming acini with stromal invasion. Diagnosis was malignant carcinoid of the pancreas, T2 N0 M0. At follow-up of three and a half years, the patient was found symptom-free and there was no evidence of recurrence. Mediscope Vol. 7, No. 1: Jan 2020, Page 58-62


2020 ◽  
Vol 8 (3) ◽  
pp. e001121
Author(s):  
Caroline Knox Benham ◽  
Vincent Doré ◽  
Pierre-Yves Mulon

An adult Highland cow weighing 380 kg presented following a five-day history of inappetence, recumbency and trauma inflicted by herd-mates. Physical exam demonstrated significant swelling of the right ventral abdomen with skin excoriations. Abdominal ultrasound of the bulging area indicated significant oedema within pockets, thinning of the right body wall compared with the left side, as well as accumulation of free abdominal fluid. Severe mastitis was noted in three quarters of its udder. The patient was stabilised with intravenous fluids, electrolytes and a belly band. It developed severe, haemorrhagic diarrhoea over the following days, and an exploratory laparotomy was performed. A complete 50 cm-long abdominal wall laceration in the caudoventral right paralumbar fossa was repaired, and jejunal resection and anastomosis performed. The patient recovered with supportive care. Surgical complications included postoperative pneumonia and development of a surgical site infection. The patient maintains good quality of life.


2019 ◽  
Vol 05 (04) ◽  
pp. e142-e145
Author(s):  
Tanweerul Huda ◽  
Mahendra Pratap Singh

AbstractTeratoma can be defined as a true neoplasm that contains tissues that either are foreign to the primary site of origin or are histologically diverse and represent more than one of the embryonic germ layers. A 20-year-old female patient presented with chief complaints of swelling in the right upper abdomen since childhood and back pain for the past 4 years. Per abdomen, examination revealed a lump of around 15 cm in size in the right hypochondrial region extending to the epigastric region. Contrast-enhanced computed tomography abdomen revealed a 14.3 × 14.1 × 17.4 cm well-defined heterogeneously hypoattenuating nonenhancing complex cystic mass with focal areas of calcifications and fat attenuation in retroperitoneum. The patient was taken up for exploratory laparotomy and a tumor was found in the retroperitoneum, retrocavally and was excised with due care. Histopathological examination features were suggestive of mature cystic teratoma. The postoperative stay was uneventful.


2014 ◽  
Vol 2014 ◽  
pp. 1-4
Author(s):  
Seyyed Reza Fatemi ◽  
M. Ghobakhlou ◽  
L. Alizadeh

Retroperitoneal pseudotumor is an extremely rare presentation of extrapulmonary tuberculosis. The diagnosis of this paucibacillary disease is difficult which is usually misdiagnosed as a malignant tumor. High index of suspicion is required for early diagnosis and treatment of retroperitoneal pseudotumor which can affect prognosis of this disease. Because of its rarity and difficult diagnosis, we report an 18-year-old immunocompetent girl who presented with abdominal pain and vomiting. Upper endoscopy showed an exudative mass between the second and third parts of duodenum. Abdominal computed tomography (CT) revealed a large retroperitoneal mass with extension into small bowel. Exploratory laparotomy and histopathological examination of tissue showed calcified granuloma. Ziehl-Neelsen staining and PCR confirmed the tuberculosis. The patient was successfully treated with standard antituberculosis therapy.


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