scholarly journals Carcinosarcoma of the bladder: case report and review of the literature

2013 ◽  
Vol 5 (4) ◽  
pp. 69
Author(s):  
Arda Akoluk ◽  
Yagil Barazani ◽  
Denisa Slova ◽  
Sovrin Shah ◽  
Basir Tareen
Keyword(s):  
Case Report ◽  
Radical Cystectomy ◽  
Transurethral Resection ◽  
Bladder Tumour ◽  
Muscularis Propria ◽  
Complete Resection ◽  
High Grade ◽  
Review Of The Literature ◽  
Almost All ◽  
Disease Free

Primary osteosarcomas of the bladder account for about 0.04% ofbladder neoplasms. Most of the patients in the literature expiredwithin 6 months and, in almost all of the cases in the literature,radical cystectomy with postoperative chemotherapy was thetreatment choice. A 79-year-old gentleman presented with grosshematuria. Cystoscopy demonstrated a 2- to 3-cm tumour along thelateral wall of the bladder. The tumour was resected incompletelyvia initial transurethral resection of bladder tumour (TURBT), anda second TURBT was subsequently performed to fully resect theresidual mass. Surgical pathology from these 2 resections revealedosteosarcoma with invasion into the muscularis propria. Acystoprostatectomy was performed and final pathologic specimenrevealed high-grade CIS without evidence of residual osteosarcoma.Postoperatively, the patient did not receive chemotherapy orradiation and currently remains disease-free 2 years post-radicalcystectomy. Only 33 well-documented cases of primary osteosarcomaof the bladder have been reported to date. However, thereare only 3 cases in which TURBT resulted in complete resection.

scholarly journals Complete resection of isolated hepatic metastatic uveal melanoma with a notably long disease-free period: A case report and review of the literature

2015 ◽  
Vol 10 (1) ◽  
pp. 196-200
Author(s):  
SHENGZHANG LIN ◽  
DALONG WAN ◽  
HAIYONG CHEN ◽  
KANGJIE CHEN ◽  
SHUSEN ZHENG
Keyword(s):  
Case Report ◽  
Uveal Melanoma ◽  
Complete Resection ◽  
Review Of The Literature ◽  
Disease Free

Assessment of transurethral resection of the bladder specimens with pT1 high-grade urothelial carcinoma for the predictor features of muscularis propria invasion on radical cystectomy specimens

2018 ◽  
Vol 37 ◽  
pp. 25-29
Author(s):  
Gozde (Gözde) Kir ◽  
Rabia Burcin (Burçin) Girgin ◽  
Tuce (Tuçe) Soylemez (Söylemez) ◽  
Mukaddes Kubra (Kübra) Melemez ◽  
Cumhur Selcuk (Selçuk) Topal ◽  
...  
Keyword(s):  
Urothelial Carcinoma ◽  
Radical Cystectomy ◽  
Transurethral Resection ◽  
Muscularis Propria ◽  
High Grade

Trimodality bladder-sparing approach versus radical cystectomy for invasive bladder cancer

2014 ◽  
Vol 13 (4) ◽  
pp. 428-437 ◽  
Author(s):  
Samy M. AlGizawy ◽  
Hoda H. Essa ◽  
Mostafa E. Abdel-Wanis ◽  
Ahmed M. Abdel Raheem
Keyword(s):  
Bladder Cancer ◽  
Radical Cystectomy ◽  
Phase Ii ◽  
Transurethral Resection ◽  
Residual Disease ◽  
Bladder Tumour ◽  
Phase Iii ◽  
Invasive Bladder Cancer ◽  
Combined Modality ◽  
Combined Chemoradiotherapy

AbstractPurposeTo compare the outcome among patients with invasive bladder cancer treated with cystectomy alone with outcome among those treated with combined-modality treatment in a randomised phase III trial.Patients and methodsPatients with histologically confirmed invasive non-metastatic bladder cancer T2-3, N0 and M0 were randomly assigned to two arms: Arm 1: of which all patients underwent radical cystectomy (RC) alone; and Arm 2, of which all patients were subjected to maximal transurethral resection of bladder tumour, followed 2 weeks later by combined chemoradiotherapy. The whole pelvis received 46 Gy in 23 fractions over 4·5 weeks. Chemotherapy was administered concomitantly with radiotherapy with: cisplatin 70 mg/m2 q. 3 weeks and Gemcitabine 300 mg/m2 D 1, 8 and 15 q. 3 weeks for two cycles. Patients who had complete response were shifted to phase II treatment: 20 Gy/10 fractions/2 weeks to the bladder. Patients with residual tumour underwent RC.ResultsOf the 80 patients assigned Arm 2, a visibly completed transurethral resection of the bladder tumour was possible in 48 patients (60%). Phase I of combined chemoradiotherapy (CCRT) was accomplished in 74 patients. Post-induction urologic evaluation revealed no evidence of disease in 62 patients (83·8%) and residual disease in 12 patients (16·2%). Phase II of CCRT was completed in 58 of the 62 patients. The median follow-up for all patients is 27 months (range: 4–49). The 3-year overall survival (OS) for the combined-modality group and for the surgery group were 61 and 63%, respectively (p = 0·425), whereas the disease-specific survival (DSS) for each group was 69 and 73%, respectively (p = 0·714). The 3-year OS with bladder preservation for Arm 2 patients was 50%.Multivariate analysis for the whole series showed that tumour stage and performance status (PS) were the only factors independently associated with DSS, although PS was the only factor independently associated with OS. In addition, residual disease after transurethral resection of the bladder tumour in Arm 2 patients was independently associated with both DSS and OS.Acute toxicity was moderate and most of the late toxicities were grade 2 with no grade 4 toxicity and no treatment-related deaths, none required cystectomy for bladder contraction.ConclusionThis study demonstrates that trimodality bladder-preserving approach represents a valid alternative for suitable patients. The OS and DSS rates of patients treated with trimodality bladder-preserving protocol are comparable to the results reported on patients treated with immediate radical cystectomy.

High grade dedifferentiated liposarcoma. Case report and review of the literature

2010 ◽  
Vol 34 (8) ◽  
pp. 737-739
Author(s):  
G. García-Fadrique ◽  
E. Morán Pascual ◽  
G. Morales Solchaga ◽  
A. Soto ◽  
J.F. Morera ◽  
...  
Keyword(s):  
Case Report ◽  
Dedifferentiated Liposarcoma ◽  
High Grade ◽  
Review Of The Literature

scholarly journals Posttraumatic Intramuscular Nodular Fasciitis in a 7-Year-Old Boy: Case Report and Review of the Literature

2021 ◽  
pp. 1-4
Author(s):  
Markus Denzinger ◽  
Markus Denzinger ◽  
Sandra Steininger ◽  
Niels Zorger ◽  
Patricia Reis Wolfertstetter ◽  
...  
Keyword(s):  
Case Report ◽  
Rare Disease ◽  
Complete Resection ◽  
Primary Resection ◽  
Histopathological Diagnosis ◽  
Nodular Fasciitis ◽  
Pectoralis Muscle ◽  
Conservative Approach ◽  
Review Of The Literature

Nodular fasciitis is a rare disease, and its diagnosis is difficult. We present a case report of a seven-year-old child with progredient swelling of the left pectoralis muscle three weeks after trauma. After histopathological diagnosis, we performed complete resection. Normally, a conservative approach with regular follow-up is regarded as appropriate since nodular fasciitis does have the capability to regress spontaneously. Since recent publications indicate the possibility of malignant transformation, the complete primary resection also has to be discussed as therapy of choice.

scholarly journals High-grade testicular diffuse B lymphoma, a rare localization: a case report and review of the literature

2020 ◽  
Vol 11 (1) ◽  
pp. 23-25
Author(s):  
Zakaria Ahmed Youbi ◽  
Sena Yossi ◽  
Pierre Sesques ◽  
Hassan Jouhadi
Keyword(s):  
Case Report ◽  
High Grade ◽  
Review Of The Literature ◽  
B Lymphoma

scholarly journals Monophasic Synovial Sarcoma of the Infratemporal Fossa—Case Report and Review of the Literature

2017 ◽  
Vol 13 (01) ◽  
pp. 01
Author(s):  
Ignacio Mendoza ◽  
Ilson Sepúlveda ◽  
Geraldine Ayres ◽  
◽  
◽  
...  
Keyword(s):  
Case Report ◽  
Soft Tissue ◽  
South America ◽  
Head And Neck ◽  
Synovial Sarcoma ◽  
Infratemporal Fossa ◽  
Soft Tissue Sarcomas ◽  
Complete Resection ◽  
Review Of The Literature ◽  
Histological Features

Synovial sarcoma (SS) represents about 10% of all soft tissue sarcomas. It is believed that its origin would be found in cells that are related neither to ultrastructural nor to histological features of the synovial tissue. Head and neck is very rarely affected, with the lower extremities being most frequent. Complete resection with or without radiotherapy and chemotherapy is currently considered the best available therapy. This time we present the case of a patient with SS located in the infratemporal fossa, its diagnosis, treatment and evolution. According to our knowledge it is the first reported case in South America.

scholarly journals Recurrence and upstaging rates of T1 high-grade urothelial carcinoma of the bladder on repeat resection in a Canadian, resource-limited, healthcare system

2018 ◽  
Vol 12 (8) ◽  
Author(s):  
Adam Kinnaird ◽  
Peter Dromparis ◽  
Howard Evans
Keyword(s):  
Urothelial Carcinoma ◽  
Healthcare System ◽  
Bladder Tumour ◽  
Muscularis Propria ◽  
High Grade ◽  
Recurrence Rates ◽  
Repeat Resection ◽  
Resource Limited ◽  
Carcinoma Of The Bladder ◽  
Muscle Invasive

Introduction: Non-muscle-invasive bladder cancer is the most expensive malignancy to treat. Current Canadian guidelines recommend repeat transurethral resection of bladder tumour (TURBT) within six weeks after initial resection of T1 high-grade (T1HG) urothelial carcinoma, prior to initiation of intravesical bacillus Calmette- Guerin treatment. This is a burden on operating room usage and adds further cost and risk of complications. Internationally, major cancer centres report significant rates of recurrence and upstaging on repeat resection, however, minimal Canadian data is available. We aimed to determine the rate of recurrence and upstaging in a resource-limited, Canadian healthcare system.Methods: A retrospective review of patients receiving TURBT between November 2009 and November 2014 was performed. Patients were included if they had all three of the following: a pathological diagnosis of T1HG, adequate muscularis propria present in the specimen, and a repeat resection.Results: We reviewed 3166 patients who underwent TURBT and found 173 to meet our inclusion criteria. The overall recurrence and upstaging rates were 57.2% and 9.2%, respectively. Tumour recurrence and upstaging occurred more often in patients who had repeat resection after 12‒24 weeks compared to those patients whose repeat resection occurred within 12 weeks.Conclusions: Although recurrence rates are similar, we have found upstaging rates to be three- to four-fold lower than those previously reported. Despite this, one in 10 patients will be upstaged, justifying use of this resource within our healthcare system. Finally, timely repeat resection, within 12 weeks appears to be associated with preventing disease progression.

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