Study on the synthesis of thioamides from aldehyde N-tert-butylsulfinyl amide and sulfur in aqueous media

2021 ◽  
pp. 54-60
Author(s):  
Pham Xuan Thao
Keyword(s):  
Organic Chemistry ◽  
Metal Complex ◽  
Organic Synthesis ◽  
Noble Metal ◽  
High Temperatures ◽  
Bioactive Compounds ◽  
Plant Protection ◽  
Aqueous Media ◽  
Environmentally Friendly ◽  
Straightforward Method

Thioamides have been widely used in the fields of medicine and organic chemistry, some of which are essential bioactive compounds, plant protection agents, and drugs. It could also be used as a vulcanizing agent, an additive to lubricants and greases, and a ligand in organic synthesis. Usually, thioamide is synthesized at high temperatures or in the microwave using an expensive noble metal complex as catalysts. This paper presented a straightforward method for synthesizing thioamides by using N-tert-butylsulfinyl amide, aldehyde, and sulfur. The reaction was carried out in water, which is an environmentally friendly solvent. The reaction selectivity and yield were up to 89%.

BIOCATALYST FOR ENVIRONMENTALLY FRIENDLY PROCESSES OF ORGANIC SYNTHESIS AND BIODIESEL PRODUCTION

Tsitologiya ◽  
2018 ◽  
Vol 60 (7) ◽  
pp. 567-571
Author(s):  
A. I. Sidorenko ◽  
◽  
A. V. Sklyarenko ◽  
S. V. Yarotsky ◽  
◽  
...  
Keyword(s):  
Organic Synthesis ◽  
Environmentally Friendly ◽  
Biodiesel Production

The molecular diversity of 1,8-diaminonaphthalene in organic chemistry

2020 ◽  
Vol 23 ◽  
Author(s):  
Ghodsi Mohammadi Ziarani ◽  
Fatemeh Mohajer ◽  
Suraj N. Mali
Keyword(s):  
Organic Chemistry ◽  
Organic Synthesis ◽  
Molecular Diversity ◽  
Organic Reactions ◽  
Recent Application ◽  
Organic Structure

: 1,8-diaminonaphthalene (1,8-DAN) with special organic structure was applied in organic synthesis to provide efficient complex scaffolds, through the two or four-component fashion. This review highlights its recent application in organic reactions under different conditions and heterogynous catalysts to produce various molecules, which were used as medicines, sensors, and dyes.

Heterogeneous System in Organic Synthesis: A Review

2020 ◽  
Vol 17 (6) ◽  
pp. 740-753
Author(s):  
Bishwajit Changmai ◽  
Gunindra Pathak ◽  
Jasha Momo H. Anal ◽  
Lalthazuala Rokhum
Keyword(s):  
Organic Synthesis ◽  
Heterogeneous System ◽  
Heterogeneous Catalysts ◽  
Solid Phase Synthesis ◽  
Solid Phase ◽  
Environmentally Friendly ◽  
Henry Reaction ◽  
Phase Synthesis ◽  
Recent Developments ◽  
Recovery And Reuse

Due to its inherent advantages such as easy recovery and reuse of the catalysts/ reagents, and environmentally friendly nature, the heterogeneous system has gain popularity in the realm of organic synthesis. In recent years, several chemically or biologically potent molecules are achieved through heterogeneous synthesis strategies. By recalling some of the classical fundamentals of the heterogeneous system in important organic synthesis, this mini-review outlines the recent developments in the applications heterogeneous catalysts and reagents; particularly in the solid phase synthesis, esterification and transesterification reactions to produce biodiesel, and Henry reaction.

Modern Organic Synthesis in the Laboratory

2008 ◽  
Author(s):  
Jie Jack Li ◽  
Chris Limberakis ◽  
Derek A. Pflum
Keyword(s):  
Organic Chemistry ◽  
Graduate Students ◽  
Organic Synthesis ◽  
Functional Group ◽  
Bond Formation ◽  
Reaction Conditions ◽  
Carbon Bond ◽  
Oxidation Reduction ◽  
Carbon Carbon Bond ◽  
Daunting Task

Searching for reaction in organic synthesis has been made much easier in the current age of computer databases. However, the dilemma now is which procedure one selects among the ocean of choices. Especially for novices in the laboratory, it becomes a daunting task to decide what reaction conditions to experiment with first in order to have the best chance of success. This collection intends to serve as an "older and wiser lab-mate" one could have by compiling many of the most commonly used experimental procedures in organic synthesis. With chapters that cover such topics as functional group manipulations, oxidation, reduction, and carbon-carbon bond formation, Modern Organic Synthesis in the Laboratory will be useful for both graduate students and professors in organic chemistry and medicinal chemists in the pharmaceutical and agrochemical industries.

scholarly journals Luminescent Supramolecular Nano- or Microstructures Formed in Aqueous Media by Amphiphile-Noble Metal Complexes

2020 ◽  
Vol 2020 ◽  
pp. 1-24 ◽  
Author(s):  
Carmen Cretu ◽  
Loredana Maiuolo ◽  
Domenico Lombardo ◽  
Elisabeta I. Szerb ◽  
Pietro Calandra
Keyword(s):  
Noble Metal ◽  
Smart Materials ◽  
Self Assembly ◽  
Noble Metals ◽  
Photophysical Properties ◽  
Aqueous Media ◽  
Molecular Architecture ◽  
Stimuli Responsive ◽  
Panoramic View ◽  
Amphiphilic Molecules

The involvement of metal ions within the self-assembly spontaneously occurring in surfactant-based systems gives additional and interesting features. The electronic states of the metal, together with the bonds that can be established with the organic amphiphilic counterpart, are the factors triggering new photophysical properties. Moreover, the availability of stimuli-responsive supramolecular amphiphile assemblies, able to disassemble in a back-process, provides reversible switching particularly useful in novel approaches and applications giving rise to truly smart materials. In particular, small amphiphiles with an inner distribution, within their molecular architecture, of various polar and apolar functional groups, can give a wide variety of interactions and therefore enriched self-assemblies. If it is joined with the opportune presence and localization of noble metals, whose chemical and photophysical properties are undiscussed, then very interesting materials can be obtained. In this minireview, the basic concepts on self-assembly of small amphiphilic molecules with noble metals are shown with particular reference to the photophysical properties aiming at furnishing to the reader a panoramic view of these exciting problematics. In this respect, the following will be shown: (i) the principles of self-assembly of amphiphiles that involve noble metals, (ii) examples of amphiphiles and amphiphile-noble metal systems as representatives of systems with enhanced photophysical properties, and (iii) final comments and perspectives with some examples of modern applications.

scholarly journals Cycloaddition of Thiourea- and Guanidine-Substituted Furans to Dienophiles: A Comparison of the Environmentally-Friendly Methods

2020 ◽  
Vol 3 (1) ◽  
pp. 57
Author(s):  
Luka Barešić ◽  
Davor Margetić ◽  
Zoran Glasovac
Keyword(s):  
High Pressure ◽  
Functional Groups ◽  
Organic Synthesis ◽  
High Speed ◽  
Environmentally Friendly ◽  
Microwave Assisted ◽  
Pressure Synthesis ◽  
Ultrasound Assisted ◽  
Substituted Furans ◽  
Guanidine Moiety

The cycloaddition strategy was employed in order to obtain a 7-oxanorbornene framework substituted with a guanidine moiety or its precursor functional groups: protected amine or thiourea. In order to optimize the conditions for the cycloaddition, several environmentally-friendly methods—microwave assisted organic synthesis, high pressure synthesis, high speed vibrational milling, and ultrasound assisted synthesis—were employed. The outcomes of the cycloaddition reactions were interpreted in terms of endo/exo selectivity, the conversion of the reactants to the product, and the isolated yields. In general, our results indicated the HP and HSVM approaches as the methods of choice to give good yields and conversions.

scholarly journals DABCO Catalyzed Synthesis of Xanthene Derivatives in Aqueous Media

2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
Pradeep Paliwal ◽  
Srinivasa Rao Jetti ◽  
Anjna Bhatewara ◽  
Tanuja Kadre ◽  
Shubha Jain
Keyword(s):  
Reaction Time ◽  
Aqueous Media ◽  
Environmentally Friendly ◽  
The Other ◽  
Short Reaction Time ◽  
Xanthene Derivatives ◽  
Reaction Proceeds ◽  
Conventional Methods

The reaction of 5,5-dimethylcyclohexane-1,3-dione with various heteroarylaldehydes afforded the corresponding heteroaryl substituted xanthene derivatives 1(a–f). The reaction proceeds via the initial Knoevenagel, subsequent Michael, and final heterocyclization reactions using 1,4-diazabicyclo[2.2.2]octane (DABCO) as a catalyst in aqueous media. The synthesized heteroaryl substituted xanthenes 1(a–f) reacted with malononitrile to obtain different alkylidenes 2(a–f). Short reaction time, environmentally friendly procedure, avoiding of cumbersome apparatus, and excellent yields are the main advantages of this procedure which makes it more economic than the other conventional methods.

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