scholarly journals Evaluation of the Applicability of the Standard Method of Ts Iso 15553 in Analysis of Cryptosporidium Oocysts and Giardia Cysts in Drinking Waters Using External Quality Control Samples

2017 ◽  
Vol 74 (50) ◽  
pp. 7-12
Author(s):  
Şule Şenses Ergül ◽  
Pınar Kaynar ◽  
Mustafa Yılmaz ◽  
Yıldırım Cesaretli ◽  
Mustafa Kemal Başarılı ◽  
...  
Keyword(s):  
Quality Control ◽  
Standard Method ◽  
External Quality Control ◽  
External Quality ◽  
Drinking Waters ◽  
Cryptosporidium Oocysts ◽  
Control Samples ◽  
Giardia Cysts

Development of the optimal procedure for increasing HbA1c concentration in control materials for external quality assessment

MedPharmRes ◽  
2021 ◽  
Vol 5 (3) ◽  
pp. 11-15
Author(s):  
Huy Quang Vu ◽  
Tuan Manh Ha ◽  
Triet Hy Van ◽  
Huynh Tien Nguyen ◽  
Phuc Thi Diem Huynh ◽  
...  
Keyword(s):  
Quality Control ◽  
Medical Laboratory ◽  
Medical Decision ◽  
Donor Blood ◽  
External Quality Control ◽  
External Quality ◽  
Optimal Procedure ◽  
Hba1c Concentration ◽  
Control Samples

Background: The research aimed to increase certain HbA1c concentrations at medical decision levels for external quality control samples from healthy donor blood. Methods: The in vitro study was performed from October 2019 to January 2021 at Quality Control Center for Medical Laboratory at University of Medicine and Pharmacy at Ho Chi Minh City. The study observed on the conditions including the optimal buffer solutions (BAGPM, BPS, Ringer, Saline), temperature (2ºC - 8ºC, 22ºC - 24ºC, 37ºC), and glucose concentration (100 mM, 305 mM, 500 mM) affecting the HbA1c concentration in vitro to make the external quality control samples fell in normal, prediabetes, and diabetes range. At every condition, the HbA1c concentration was measured by Tina Quant method to look for the optimal procedure to increase HbA1c concentration required of the external quality control protocol. Results: The highest HbA1c concentration (11.57±0.2%) was found in BAGPM solution with 100 mM glucose after 15 days with the baseline HbA1c 5.43±0.13%; the HbA1c level increase dramatically at 37ºC in BAGPM 500 mM glucose solution in fifteen days (40.03±1.05%). Conclusions: The appropriate conditions were identified to prepare HbA1c standards for prediabetic and diabetic levels. The standards for HbA1c concentrations were recommended to prepare by incubating RBCs from non-diabetic donor blood in BAGPM solution containing glucose at 37ºC for 24 hours. Glucose concentrations should be 100 mM and 500 mM, respectively, for prediabetic level (HbA1c ~ 6.0 ± 0.12%) and diabetic level (HbA1c ~ 9.6 ± 0.17%).

Use of plasmid-derived external quality control samples in pharmacogenetic testing

2008 ◽  
Vol 9 (9) ◽  
pp. 1261-1266 ◽  
Author(s):  
Tahar van der Straaten ◽  
Jesse Swen ◽  
Renee Baak-Pablo ◽  
Henk-Jan Guchelaar
Keyword(s):  
Quality Control ◽  
External Quality Control ◽  
External Quality ◽  
Pharmacogenetic Testing ◽  
Control Samples

scholarly journals Performance of the Boditech iCHROMA Covid-19 IgG antibody assay with the external quality control for UK NIBSC (National Institute of Biological Standards and Control)

2020 ◽  
Vol 2 (8) ◽  
pp. 01-04
Author(s):  
J Bolodeoku Bolodeoku
Keyword(s):  
Quality Control ◽  
Quality Control Material ◽  
External Quality Control ◽  
Antibody Assay ◽  
Igg Antibody ◽  
Control Material ◽  
External Quality ◽  
The Uk ◽  
And Control ◽  
Control Samples

Background: There is a need for laboratories to participate in EQA schemes to achieve a harmonization of test results and to improve serological testing and research on COVID-19 and SARS-CoV-2. The Boditech iCHROMA point of care immunoassay analyser has a Covid-19 antibody assay for the qualitative determination of IgG antibodies in human whole blood/serum/plasma. The National Institute for Biological Standards and Control (NIBSC) in the United Kingdom has a portfolio of reference and research reagents, including reagents for EQA that are available to laboratories to help them set up and develop accurate diagnostic tests for SARS-CoV-2 assays. Objectives: To determine the performance of the Boditech iCHROMA Covid-19 IgG antibody assay using the external quality control material provided by the UK NIBSC (National Institute for Biological Standards and Control). Results: The Boditech iCHROMA Covid-19 IgG assay using the cut off index >1.1, reported the results of the 33 positive control samples as positive with index range from 19.50 – 29.00, with a mean of 23.75 and standard deviation of SD of 2.53. It also reported the results of the 33 negative control samples as negative with an index range of 0.00 for all samples. Conclusion: The performance of the Boditech iCHROMA Covid-19 IgG antibody assay using external quality control material from the UK NIBSC was very good, confirming the precision of the Boditech iCHROMA Covid 19 IgG antibody method.

scholarly journals The Schemes of External Quality Control in Laboratory Medicine in the Balkans

2007 ◽  
Vol 26 (3) ◽  
pp. 245-247
Author(s):  
Petros Karkalousos
Keyword(s):  
Quality Control ◽  
Scientific Community ◽  
Clinical Chemistry ◽  
Laboratory Medicine ◽  
External Quality Control ◽  
External Quality ◽  
The Balkans ◽  
Control Schemes ◽  
Balkan Countries ◽  
Balkan Region

The Schemes of External Quality Control in Laboratory Medicine in the Balkans There are many differences between the national External Quality Control Schemes all around Europe, but the most important ones are certainly those between the countries of the Balkan region. These differences are due to these countries' different political and financial development, as well as to their tradition and the development of clinical chemistry science in each one. Therefore, there are Balkan countries with very developed EQAS and others where there is no such a scheme. Undoubtedly, the scientific community in these countries wants to develop EQAS despite of the financial and other difficulties.

scholarly journals Necessity of External Quality Control for anti-Mycoplasma pneumoniae IgM antibodies

2008 ◽  
Vol 23 (2) ◽  
Author(s):  
Massimo De Paschale ◽  
Luisa Belvisi ◽  
Debora Cagnin ◽  
Teresa Cerulli ◽  
Maria Teresa Manco ◽  
...  
Keyword(s):  
Quality Control ◽  
Mycoplasma Pneumoniae ◽  
External Quality Control ◽  
External Quality ◽  
Igm Antibodies

scholarly journals External Quality Assessment in the Evaluation of Laboratory Performance of Faecal Culture

2017 ◽  
Vol 10 ◽  
pp. 117863611769125
Author(s):  
Salla J Kiiskinen ◽  
Tarja Ojanen ◽  
Yvonne Björkman ◽  
Harri Laitinen ◽  
Anja Siitonen
Keyword(s):  
Public Health ◽  
Quality Control ◽  
External Quality Assessment ◽  
False Negative ◽  
The Other ◽  
Epidemiological Surveillance ◽  
External Quality Control ◽  
External Quality ◽  
Faecal Culture

In Finland, all laboratories carrying out diagnostics of infectious diseases in humans are approved by the Regional State Administrative Agencies and are obligated to participate in External Quality Assurance rounds. Performance in these rounds is thought to reflect the quality of laboratory work. In the 6-year study period, 17 Finnish laboratories received 48 simulated faecal specimens for the culturing of diarrhoeal pathogens, yielding altogether 586 faecal culture External Quality Control specimens and 581 reports. The results were correct in 92% of all reports and in 67% of all specimens. False-negative Salmonella results were given for 2 of the 18 specimens, one with biochemically atypical Salmonella strain and the other with a low count of Salmonella cells. False-negative Shigella report was given for 6 of the 7 specimens in some participating laboratory. Detection of all common faecal pathogens is especially relevant to patient safety, public health, and epidemiological surveillance.

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