scholarly journals Ultrasound Evaluation of Carotid Intima-Media Thickness in Children

2015 ◽  
Vol 22 (11) ◽  
pp. 1141-1147 ◽  
Author(s):  
Matias Epifanio ◽  
Matteo Baldisserotto ◽  
Edgar E. Sarria ◽  
Arthur Lazaretti ◽  
Rita Mattiello
2019 ◽  
Vol 37 (4) ◽  
pp. 428-434 ◽  
Author(s):  
Jovita Lane Soares Santos Zanini ◽  
Tânia Maria Barreto Rodrigues ◽  
Cristina Botelho Barra ◽  
Maria Francisca Tereza Freire Filgueiras ◽  
Ivani Novato Silva

ABSTRACT Objective: To contribute to the assessment of normal parameters of carotid intima-media thickness (CIMT) in healthy adolescents. Methods: A cross-sectional study was conducted through clinical, laboratory and ultrasound evaluation in 61 healthy adolescents. The inclusion criteria consisted of being in good health. The exclusion criteria were: presence or history of any chronic disease; being obese or overweight according to the World Health Organization (WHO) established criterion; continuous use of medication; or presenting a febrile condition or requiring medication within 48-hours prior to assessment. The pubertal stages were evaluated using the Tanner criteria. The high-resolution B-mode ultrasound examinations were performed according to the recommendations of the Consensus Statement from the American Society of Echocardiography Carotid Intima-Media Thickness Task Force. Results: Adolescents were 14±2.6 years old, 62.3% female, 19 (31%) at early puberty (Tanner II and III), and 38 (62%) at late puberty (Tanner IV and V). They presented normal clinical and laboratorial parameters. CIMT values were 0.46±0.04 to 0.55±0.04 mm on the right and 0.48±0.02 to 0.53±0.04 mm on the left, according to pubertal maturation. CIMT values increased significantly on the right and left sides, according to pubertal stage (p<0.001 and p=0.016), and maximum internal diameters of the common carotid artery (p<0.025 and p<0.003). It was higher in males compared to females. Conclusions: An increase in CIMT in the healthy adolescents group, according to both age, and the degree of pubertal maturation should be considered when evaluating adolescents in diagnostic procedures.


2017 ◽  
Vol 4 (2) ◽  
pp. 16 ◽  
Author(s):  
Ibrahim A. Awad ◽  
Hanan Y. Abbas

Objective: The study purpose was to assess the change of carotid artery intima-media thickness (CAIMT) in patients with cardiovascular risk factors (CVRF), and determine the main factor that causing the abnormal IMT.Methods: We collected the data of 89 patients who underwent a carotid artery ultrasound between February 2011 and November 2012 (43 men and 46 women aged between 20-80 years old). All patients included in the study had one of the following cardiovascular risk factors: smoking (n = 40), arterial hypertension (n = 25) or diabetes mellitus (n = 24). The IMT of the common carotid artery was measured and the results were correlated with the recorded risk factor. Correlation with the patient’s age and gender was also performed.Results: The study revealed abnormal IMT (> 1 mm) in a total of 71 (79.8%) patients. These included 22 (88%) patients with hypertension, 19 (79.2%) patients with diabetes mellitus and 30 (75%) patients who were smokers (p < .05 for all 3 risk factors). While aging was also associated with increased IMT (p < .05), no gender differences were noted (p > .05).Conclusions: The present study showed that ultrasound is an excellent, noninvasive method for evaluation of carotid intima-media thickness. The main risk factors associated with abnormal carotid IMT were hypertension, diabetes mellitus, smoking andpatient’s age.


Author(s):  
Adhi Permana ◽  
Ian Effendi ◽  
Taufik Indrajaya

Chronic kidney disease is associated with a high mortality rate, especially cardiovascular disease associated with mineral and bone disorders. Sclerostin is an inhibitor of Wnt signaling which has the effect of increasing the occurrence of vascular calcification in patients with chronic kidney disease. There are several studies that show different results. Carotid intima media thickness ultrasound examination is a tool to identify atherosclerosis which is part of vascular calcification. The aim of this study is to look at the correlation of sclerostin with carotid intima media thickness (CIMT) in patients with chronic kidney disease undergoing hemodialysis. In this cross section, the concentration of sclerostin was measured by examination of enzymed linked immunosorbent assay. CIMT measurement by ultrasound mode B examination. There were 40 patients in this study. The mean sclerostin level was 256.68 ± 127.76 pg / ml. Sclerostin levels are declared high if above 162 pg / ml there are 30 people. CIMT thickening was present in 11 patients. There was no significant correlation of serum sclerostin with CIMT in patients with chronic kidney disease undergoing hemodialysis (r-0.32 p0,847). In multivariate linear regression, hemodialysis duration is an independent factor that is significantly significant with CIMT. There was no significant correlation of serum sclerostin with CIMT in patients with chronic kidney disease undergoing hemodialysis.


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