scholarly journals Efeitos do hiperboloide masticator apparatus na desordem temporomandibular - Estudo de caso

2016 ◽  
Vol 14 (4) ◽  
pp. 641-646 ◽  
Author(s):  
Carolina Marciela Herpich ◽  
Cid André Fidelis De Paula Gomes ◽  
Yasmin El Hage ◽  
Igor Phillip dos Santos Gloria ◽  
Ana Paula Amaral ◽  
...  
Keyword(s):  
Apparatus 3

Introdução: A disfunção temporomandibular caracteriza-se por um conjunto de alterações clínicas envolvendo os músculos mastigatórios, a articulação temporomandibular e outras estruturas associadas. Objetivo: A estimulação proprioceptiva condicionada pelo uso do hiperboloide diminui o quadro álgico e aumenta a amplitude do movimento mandibular. Métodos: Apresentamos o caso de uma jovem de 22 anos com diagnostico de Disfunção temporomandibular, que recebeu o tratamento fisioterapêutico utilizando hiperboloide mastigador apparatus 3 vezes por semana durante 8 semanas sendo realizadas duas avaliações específicas: extensão vertical do movimento mandibular e mensuração do limiar de dor por pressão sobre o músculo masseter, pré atendimento, pós imediato e pós tratamento. Resultados: Observou-se aumento expressivo na abertura mandibular e no aumento de limiar de dor. Conclusão: O uso do hiperboloide levou a um aumento mobilidade mandibular e diminuição de dores nos músculos masseteres e consequente melhora na mastigação.

scholarly journals Development of USP Apparatus 3 Dissolution Method with IVIVC for Extended Release Tablets of Metformin Hydrochloride and Development of a Generic Formulation

2019 ◽  
Vol 67 (1) ◽  
pp. 23-31
Author(s):  
Thamara de Carvalho Mendes ◽  
Alice Simon ◽  
Jaqueline Correia Villaça Menezes ◽  
Eduardo Costa Pinto ◽  
Lucio Mendes Cabral ◽  
...  
Keyword(s):  
Extended Release ◽  
Metformin Hydrochloride ◽  
Dissolution Method ◽  
Apparatus 3 ◽  
Usp Apparatus

scholarly journals Physicochemical and dissolution profile characterization of pellets containing different binders obtained by the extrusion-spheronization process

2012 ◽  
Vol 48 (3) ◽  
pp. 379-388 ◽  
Author(s):  
Michele Georges Issa ◽  
Letícia Pessole ◽  
Andrea Ikeda Takahashi ◽  
Newton Andréo Filho ◽  
Humberto Gomes Ferraz
Keyword(s):  
Small Diameter ◽  
Immediate Release ◽  
Physicochemical Characteristics ◽  
The United States ◽  
Dissolution Profile ◽  
Orally Disintegrating Tablets ◽  
Apparatus 3 ◽  
Usp Apparatus ◽  
Extrusion Spheronization

With the purpose of evaluating the behavior of different polymers employed as binders in small-diameter pellets for oral administration, we prepared formulations containing paracetamol and one of the following polymers: PVP, PEG 1500, hydroxypropylmethylcellulose and methylcellulose, and we evaluated their different binding properties. The pellets were obtained by the extrusion/spheronization process and were subsequently subjected to fluid bed drying. In order to assess drug delivery, the United States Pharmacopeia (USP) apparatus 3 (Bio-Dis) was employed, in conjunction with the method described by the same pharmacopeia for the dissolution of paracetamol tablets (apparatus 1). The pellets were also evaluated for granulometry, friability, true density and drug content. The results indicate that the different binders used are capable of affecting production in different ways, and some of the physicochemical characteristics of the pellets, as well as the dissolution test, revealed that the formulations acted like immediate-release products. The pellets obtained presented favorable release characteristics for orally disintegrating tablets. USP apparatus 3 seems to be more adequate for discriminating among formulations than the basket method.

scholarly journals Evaluation of USP apparatus 3 for dissolution testing of immediate-release products

AAPS PharmSci ◽  
2002 ◽  
Vol 4 (1) ◽  
pp. 1-5 ◽  
Author(s):  
Lawrence X. Yu ◽  
Jin T. Wang ◽  
Ajaz S. Hussain
Keyword(s):  
Immediate Release ◽  
Dissolution Testing ◽  
Apparatus 3 ◽  
Usp Apparatus
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