Analisis Lingkungan Pengendalian dalam Pelaksanaan SPIP di Inspektorat Kabulaten Nagekeo

ABSTRACTThe control environment is a crucial object in the whole control activities carried out, thus without an effective control environment, internal control will not work effectively. The Inspectorate of Nagekeo Regency as an institution that assists the Regent in supervising the implementation of regional Government by conducting inspections, studies, evaluations, and other supervisory activities at other government institutions within the Scope of Government of Nagekeo Regency, have to have an adequate control environment in support of effective internal control activities. The used object of research in this study is the control environment built by the Regency Inspectorate Employees who taken by purposive sampling technique. This measure is used as a comparison in the control environment assessment category. This study uses a quantitative-descriptive technique with a field research approach at the Inspectorate of Nagekeo Regency. The variables of this study are the control environment sub-elements with eight variables which include the enforcement of integrity and ethical values, commitment to competence; Conducive leadership; Establishment of organizational structure as needed; Appropriate delegation of authority and responsibility; Formulation and implementation of sound human resource development policies; The realization of the role of an effective government internal control apparatus; and good working relationship with relevant Government Agencies. In general, the eight variables of the Nagekeo Inspectorate get a score of 2.25 with quite-adequate predicate. However, two of them that still get the inadequate predicate, including the Enforcement of Integrity and Ethics; Formulation and implementation of human resource development policies, need to get attention.

Sydney Metro and Melbourne Metro Rail Stochastic Comparison and Review

This paper aims to review an innovative artificial intelligence (AI) apparatus to enhance the rail transportation performance. In this light, the Sydney Metro and Melbourne Metro rail will be compared, since both of these Australian rail networks employ complex AI as part of their overall performance enhancement schemes. These two case studies further highlight the novel critical aspects of AI in rail transportation sector such as recalibration through smart system design and automation, nonlinear controls and precise design, modeling and control apparatus, and so on. As a part of such a view, different aspects of AI systems such as increased reliability and safety were also investigated. This research found that with such enhancements of system performance, the overall transportation functioning would ultimately be significantly improved. Subsequently, AI in the Australian context can be further refined based on comprehensive integration of the key factors.

Digital Transformation of Business Analytical Processes

Current development and management of economic activity is largely associated with the implementation of the concept of the digital economy, which poses new challenges for business intelligence. The set of tasks is formed in order to develop business intelligence so that it matches the improved management of economic subjects, and to ensure the quality of business processes when digital technologies are introduced. Improved management based on the concept of the business environment implies that monitoring principles are used to analyze the behavior of external business environment participants with the purpose to build a rational partnership relationship. The digital economy creates information opportunities in this area, as it provides the access to Big Data and their processing using Big data analytics technologies. With regard to the requirements of management, the article analyzes the behavior of elements of the internal business environment to develop a management solution to improve the effectiveness of their behavior. The high quality of the solution is provided by the information model being a highly adequate image of a particular object under control and the ability of the control apparatus to fully realize the volume of its inherent functions. Under these conditions, the digital transformation of analytical processes is based on its own information platform, which should use breakthrough digital technologies. The research uses such methods as systemic analysis to generalize the modern concepts of economic system management, development of digital technologies and their introduction into management decision-making processes.

The Heat Shock Protein 40-Type Chaperone MASH Supports the Endoplasmic Reticulum-Associated Degradation E3 Ubiquitin Ligase MAKIBISHI1 in Medicago truncatula

Jasmonates (JA) are oxylipin-derived phytohormones that trigger the production of specialized metabolites that often serve in defense against biotic stresses. In Medicago truncatula, a JA-induced endoplasmic reticulum-associated degradation (ERAD)-type machinery manages the production of bioactive triterpenes and thereby secures correct plant metabolism, growth, and development. This machinery involves the conserved RING membrane-anchor (RMA)-type E3 ubiquitin ligase MAKIBISHI1 (MKB1). Here, we discovered two additional members of this protein control apparatus via a yeast-based protein–protein interaction screen and characterized their function. First, a cognate E2 ubiquitin-conjugating enzyme was identified that interacts with MKB1 to deliver activated ubiquitin and to mediate its ubiquitination activity. Second, we identified a heat shock protein 40 (HSP40) that interacts with MKB1 to support its activity and was therefore designated MKB1-supporting HSP40 (MASH). MASH expression was found to be co-regulated with that of MKB1. The presence of MASH is critical for MKB1 and ERAD functioning because the dramatic morphological, transcriptional, and metabolic phenotype of MKB1 knock-down M. truncatula hairy roots was phenocopied by silencing of MASH. Interaction was also observed between the Arabidopsis thaliana (Arabidopsis) homologs of MASH and MKB1, suggesting that MASH represents an essential and plant-specific component of this vital and conserved eukaryotic protein quality control machinery.

An Application-Based Review of Haptics Technology

Recent technological development has led to the invention of different designs of haptic devices, electromechanical devices that mediate communication between the user and the computer and allow users to manipulate objects in a virtual environment while receiving tactile feedback. The main criteria behind providing an interactive interface are to generate kinesthetic feedback and relay information actively from the haptic device. Sensors and feedback control apparatus are of paramount importance in designing and manufacturing a haptic device. In general, haptic technology can be implemented in different applications such as gaming, teleoperation, medical surgeries, augmented reality (AR), and virtual reality (VR) devices. This paper classifies the application of haptic devices based on the construction and functionality in various fields, followed by addressing major limitations related to haptics technology and discussing prospects of this technology.

Button Operated Electromagnetic Gear Shifting System in Two Wheeler

There are disclosed an electromagnetic Type Gear Change System control apparatus for an automobile and a method of controlling such apparatus. A rotational output of an internal combustion engine is connected to drive wheels of the automobile and a load device. When a gear shifting-up of a electromagnetic type transmission is to be effected, the load applied by the load device is increased, or the load is connected to an output rotation shaft of the engine via a selectively-connecting device, thereby reducing the rotational speed of the output rotation shaft of the engine to a required level. In our project, two electromagnetic coils are coupled to the gear rod of the two ends. The two Buttons are used to activate the electro-magnetic coil so that the gear will be shifted. In this project, we aim at developing easy gear shifting mechanism for transmission which will make motor bike rider’s gear shifting very easy. Everyone desires for the smooth running of the vehicle whatsoever may be the speed of pickup of the vehicle a person is operating, but one of the most important systems which every engineer is concerned about in vehicle is gear shifting system for ensuring smooth and desired ride on their two wheelers. Some simple mechanism is arranged solenoid plunger which will help us to change the gear as per the desired torque. In this gear shifting mechanism, gear shifting is done with the help of two solenoid plungers. The up shifting and downshifting of gears is done with the help two independent switches. These two switches are connected to solenoid plungers via battery.

Dynamic regulation of translation quality control associated with ribosome stalling

Translation of problematic mRNA sequences induces ribosome stalling. Collided ribosomes at the stall site are recognized by cellular quality control machinery, resulting in dissociation of the ribosome from the mRNA and subsequent degradation of the nascent polypeptide and in some organisms, decay of the mRNA. However, the timing and regulation of these processes are unclear. We developed a SunTag-based reporter to monitor translation in real time on single mRNAs harboring difficult-to-translate poly(A) stretches. This reporter recapitulates previous findings in human cells that an internal poly(A) stretch reduces protein output ∼10-fold, while mRNA levels are relatively unaffected. Long-term imaging of translation indicates that poly(A)-containing mRNAs are robustly translated in the absence of detectable mRNA cleavage. However, quantification of ribosome density reveals a ∼3-fold increase in the number of ribosomes on poly(A)-containing mRNAs compared to a control mRNA, consistent with queues of many stalled ribosomes. Using single-molecule harringtonine runoff experiments, we observe the resolution of these queues in real-time by the cellular quality control machinery, and find that rescue is very slow compared to both elongation and termination. We propose that the very slow clearance of stalled ribosomes provides the basis for the cell to distinguish between transient and deleterious stalls, and that the human quality control apparatus predominantly targets the nascent protein rather than the mRNA.

Intermediary Liability in Russia and the Role of Private Business in the Enforcement of State Controls over the Internet

The rapid expansion of the internet in Russia, combined with its potential to instigate a social uprising, has led to the adoption of significant regulatory restrictions on online content and anonymity. Faced with new technical challenges, the Kremlin has enlisted competent and technically capable internet actors—search engines, social networks, hosting providers, and network operators—to help implement these restrictions and control the flow of information. This chapter attempts to demonstrate the evolution of intermediary liability in Russia since 2011–12, when the government drastically changed its stance on internet regulation. It describes how this regulation is followed and enforced with respect to content removal and online surveillance, and how private companies have become an integral part of the state’s internet control apparatus. The chapter examines the legislative framework, enforcement statistics, and most prominent cases for two areas of government control: content and surveillance. ‘Content’ refers to the types of information the state seeks to restrict online, while ‘surveillance’ refers to how the state collects user data and online activity. Within both categories, this chapter focuses on the obligations of intermediaries (telecom operators, web-hosting providers, and social media platforms). This chapter further complements the findings with quotations from semi-structured interviews that were conducted with executives of telecom and web-hosting companies, telecom lawyers, internet activists, and representatives of industry associations.