Disseminated TB in inpatient deaths at a tertiary care centre: an autopsy study over three decades

2021 ◽  
Vol 25 (4) ◽  
pp. 271-276
Author(s):  
U. N. Siakia ◽  
V. Vishwajeet ◽  
R. Kumar ◽  
V. Suri ◽  
K. Joshi ◽  
...  
Keyword(s):  
Tertiary Care ◽  
Reproductive Organs ◽  
Hospital Inpatient ◽  
Tertiary Care Centre ◽  
Autopsy Study ◽  
Atypical Symptoms ◽  
Significant Burden ◽  
Post Graduate Institute ◽  
The Brain ◽  
Significant Mortality

BACKGROUND: One of the most severe forms of TB, disseminated TB (dTB) is associated with significant mortality. A retrospective study was undertaken to assess the proportion of dTB among inpatient deaths and to describe the pathological spectrum of lesions. Associated comorbidities and missed dTB cases ante-mortem were also sought.METHODS: Data on autopsy-confirmed cases of dTB from over three decades (1988–2016) obtained from the departmental archives of the Post Graduate Institute of Medical Education and Research, Chandigarh, India, were reviewed for clinical details, as well as gross and histopathological findings. The proportion of autopsy-confirmed dTB were reported.RESULTS: During this period, a total of 243 autopsy-confirmed cases were retrieved. The organs most commonly involved in these cases were the lungs (90.1%), followed by the liver (72%), spleen (44%), kidneys (37%), bone marrow (17%), adrenals (12.2%), intestine (11.4%), pancreas (8.5%) and reproductive organs (6.9%). The brain was involved in 73.3% cases. In one third of cases, the diagnosis of TB was not suspected ante-mortem. Comorbid conditions were noted in 36.2% cases.CONCLUSION: A significant burden of dTB was noted among hospital inpatient deaths. Due to multi-organ involvement, dTB has atypical symptoms and may remain undiagnosed ante-mortem. Increased awareness and robust screening of TB cases are mandatory, particularly in patients with underlying comorbidities.

Maternal Autopsy Study: An Experience at Tertiary Care Centre at Nanded

2017 ◽  
Vol 10 (2) ◽  
pp. 88-93
Author(s):  
Suvernakar S.V. ◽  
◽  
anmante R.D. ◽  
Deshpande S.A. ◽  
Panchal M.G. ◽  
...  
Keyword(s):  
Tertiary Care ◽  
Care Centre ◽  
Tertiary Care Centre ◽  
Autopsy Study

scholarly journals A clinicoepidemiological study of dermatoses among paediatric population

2018 ◽  
Vol 6 (6) ◽  
pp. 2106
Author(s):  
Rohini Sharma ◽  
Sameer Abrol
Keyword(s):  
Normal Population ◽  
Tertiary Care ◽  
Age Groups ◽  
Paediatric Population ◽  
Age Group ◽  
Tertiary Care Centre ◽  
Significant Burden ◽  
Epidemiological Profile ◽  
Histopathological Studies ◽  
A Prospective Study

Background: Alike the normal population, even paediatric population encounters various dermatological conditions. Dermatosis among paediatric population can range from acute conditions, to chronic or recurrent and does carry significant burden on quality of life. It has to be dealt separately from adults as it has different symptoms, requires different treatment as has different prognosis for the same disease as compared to adults. Aim was to study the clinico-epidemiological profile of various dermatoses prevalent among the paediatric population less than 18 years.Methods: This was a prospective study done at a tertiary care centre of Jammu region. Paediatric patients less than 18 years of age attending the dermatology outpatient department were taken up for study. A detailed history was taken from the patient or attendants, detailed clinical examination was done. Also, laboratory investigations like KOH, gram stain, AFB stain, woods lamp, histopathological studies among others were done wherever required. The results were statistically evaluated and inferences drawn.Results: A total of 600 children were taken up for study. Males outnumbered the females with 302 females and 298 males. Maximum no. of patients (36.8%) were in the 6-11 years age group followed by 1-5 years age group (27%). Most common dermatoses seen over all the age groups was infections and infestations (39.1%) followed by eczematous group (16%). However, the pattern of dermatoses did vary in each age group and also was determined by the climate. Many patients had more than one dermatoses.Conclusions: This study was done to assess the burden of dematoses among paediatric population and found that various dermatoses did vary according to various age groups. Infections and infestations formed a major share.

scholarly journals Evaluation of prevalence, clinical spectrum and outcome of acute ITP in children in a tertiary care centre in Odisha, India

2017 ◽  
Vol 4 (4) ◽  
pp. 1470
Author(s):  
Jyotiranjan Champatiray ◽  
Deepak Kumar Behera ◽  
Akhil Krishnamoorthy ◽  
Shreesh Bhat
Keyword(s):  
Past History ◽  
Tertiary Care ◽  
Significant Risk ◽  
Significant Risk Factor ◽  
Complete Recovery ◽  
Tertiary Care Centre ◽  
Thrombocytopenic Purpura ◽  
Number Of Patients ◽  
Acute Itp ◽  
Post Graduate Institute

Background: Idiopathic thrombocytopenic purpura (ITP), also known as immune thrombocytopenic purpura is one of the commonest bleeding disorders encountered in children between the ages of 2 to 10 years affecting both sexes. The objectives of the study were to collect the prospectively data including age, gender, bleeding type, platelet count and other laboratory tests, treatments, responses to treatment and outcomes in children with acute ITP from 1month to 14 years of age over a period of two years.Methods: The present study was conducted in the Department of Paediatrics Shrirama Chandra Bhanj, Medical College and Hospital and Sardar Vallabhbhai Patel Post Graduate Institute of Paediatrics, Cuttack during the period October 2011-Septmber 2013.Results: Total 36 cases of hospitalized acute ITP patients were studied out of 29200 cases. Prevalence of acute ITP was found to be 12.3 per 10,000 of all hospitalized children above 1 month. Male children outnumbered female children by Ratio 1.2. Past history of URTI was present in 78% of cases. Petechaie/purpura was the universal presenting features followed by Oral / Gum bleeding in 67% of cases. 8% of patient experienced clinical bleeding requiring blood transfusion and platelet transfusion. Mean duration of Hospital stay was 6.34 days. Maximum number of Patients (69%) had complete recovery and 14% each had persistent and chronic course.Conclusions: ITP is a common pediatrics disease presenting at any age with low morbidity and mortality. Most children with acute ITP recover in weeks to months. A long-term hospital based prospective study is suggested to know any significant risk factor in patient presenting with acute ITP.

scholarly journals Craniocerebral missile injuries in civilian Kashmir – India

1970 ◽  
Vol 29 (2) ◽  
pp. 13-28 ◽  
Author(s):  
BA Rashid ◽  
MA Wani ◽  
AR Kirmani ◽  
TH Raina ◽  
S Raina
Keyword(s):  
Tertiary Care ◽  
Medical Sciences ◽  
Tertiary Care Centre ◽  
Conflict Zones ◽  
Set Up ◽  
The Third World ◽  
Tertiary Care Hospitals ◽  
Modern Era ◽  
The Brain ◽  
Overall Mortality

Background The missile injuries of the cranium and brain in the modern era have shifted from soldiers to the civilians and from the battle grounds to the populated zones due to increase in the terrorist and military strikes. The management of the victims depends on the resuscitation at the site of injury and the distance and transportation to the tertiary care centre. This article presents the details of the missile injuries to the brain, the third-world problems and the management. Material and methods A retrospective analysis of 3794 craniocerebral missile injuries, managed by the Department of Neurosurgery at Sher-I-Kashmir Institute of Medical Sciences (SKIMS) Kashmir, India, over a period of more than 21 years from September 1988 to September 2009. Patients were triaged in emergency CT-room, resuscitated and operated. Statistical software programme SPSS 11.5 was used to derive the numerical significance. Results Revealed an overall mortality of 87.69% (3327 out of 3794). Most of the deaths 79.14% (2633 out of 3327) occurred within 30 minutes of the patient’s arrival to the hospital and only 694 patients lived beyond one hour of arrival. Conclusion Presently the quantum of outcome i.e, survival and good recovery in craniocerebral missile injuries appears a meager heap compared to the huge amount of death and disability. And the situation will continue to be so unless tertiary care hospitals are set up within and around the armed and conflict zones, war torn areas and battle fields, rather than risking transportation, time of resuscitation, intervention and the results.Key words: Craniocerebral, Kashmir, Missile Injuries, Outcome.

Abstract #1100: Tumor Induced Osteomalacia: Clinical; Biochemical and Radiological Features from a Single Tertiary Care Centre with Emphasis on Functional Imaging.

2017 ◽  
Vol 23 ◽  
pp. 289
Author(s):  
Vineet Surana ◽  
Rajesh Khadgawat ◽  
Nikhil Tandon ◽  
Chandrashekhar Bal ◽  
Kandasamy Devasenathipathy
Keyword(s):  
Functional Imaging ◽  
Tertiary Care ◽  
Care Centre ◽  
Tertiary Care Centre ◽  
Radiological Features

Emerging Antimicrobial Resistance Among Methicillin Resistant Staphylococcus Aureus (MRSA) in a Tertiary Care Centre in North India

JMS SKIMS ◽  
2020 ◽  
Vol 23 (1) ◽  
pp. 48-49
Author(s):  
Javaid Ahmad Bhat ◽  
Shariq Rashid Masoodi
Keyword(s):  
Staphylococcus Aureus ◽  
Antimicrobial Resistance ◽  
Tertiary Care ◽  
Resistance Mechanisms ◽  
North India ◽  
Global Public Health ◽  
Care Centre ◽  
Tertiary Care Centre ◽  
Effective Prevention ◽  
Mupirocin Resistance

Apropos to the article by Dr Bali, titled “Mupirocin resistance in clinical isolates of methicillin-sensitive and resistant Staphylococcus aureus in a tertiary care centre of North India” (1), the authors have raised important issue of emerging antimicrobial resistance (AMR). Antimicrobial resistance is an increasingly serious threat to global public health that requires action across all government sectors and society. As per WHO, AMR lurks the effective prevention and management of an ever-increasing spectrum of infections caused by bacteria, parasites, fungi and viruses. Novel resistance mechanisms are emerging and spreading globally, threatening the man’s ability to treat common infectious diseases.

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