Reactor buildings of 600 MW CANDU nuclear power plants consist of a prestressed concrete containment structure, cylindrical in shape with a double spherical dome, and of a reinforced concrete internal structure with heavy walls and slabs that support the nuclear reactor, the primary heat transport system, control and safety mechanisms, etc. Both structures are supported on a common circular slab.In this paper, an outline of the static and seismic response analyses performed for these buildings is presented. Several computer models and codes are used and advantage is taken of the symmetry of revolution of part of the structure.By combining the results produced by the various models and accounting for discontinuities caused by openings, etc., a complete picture of the forces, displacements, or accelerations existing in the reactor building under operating conditions and during postulated accidents or seismic events may be drawn.This process has been partly automated by the development of relevant software. A flow chart of the whole analysis process is given. Key words: nuclear power plants, reactor building, containment, analysis, static, seismic, finite elements.