MATERNAL FETAL FEATURES IN A GROUP OF PREGNANT WOMEN DIAGNOSED WITH CHRONIC AUTOIMMUNE THYROIDITIS AND VITAMIN D DEFICIENCY

2019 ◽  
Author(s):  
Olesea Scrinic
Keyword(s):  
Vitamin D ◽  
Pregnant Women ◽  
Vitamin D Deficiency ◽  
Autoimmune Thyroiditis ◽  
Chronic Autoimmune Thyroiditis

scholarly journals “Vitamin D Deficiency Is More Common in Women with Autoimmune Thyroiditis: A Retrospective Study”

2021 ◽  
Vol 2021 ◽  
pp. 1-6
Author(s):  
Nino Turashvili ◽  
Lali Javashvili ◽  
Elene Giorgadze
Keyword(s):  
Vitamin D ◽  
Retrospective Study ◽  
Vitamin D Deficiency ◽  
Autoimmune Thyroiditis ◽  
Thyroid Stimulating Hormone ◽  
Primary Hypothyroidism ◽  
Thyroid Autoantibody ◽  
Chronic Autoimmune Thyroiditis ◽  
Antithyroglobulin Antibodies ◽  
Stimulating Hormone

Background. Vitamin D is a hormone that is mainly produced in the skin upon ultraviolet B radiation exposure and has important influence on various organs. In recent years, data have been collected that vitamin D deficiency plays an important role in the development of various nonskeletal diseases, including autoimmune diseases. Chronic autoimmune thyroiditis (Hashimoto’s thyroiditis) is one of the most common organ-specific autoimmune endocrine diseases. It is characterized by increased level of antithyroid peroxidase and/or antithyroglobulin antibodies in blood, which often leads to thyroid dysfunction and structural changes of the gland. There is an opinion that vitamin D deficiency may be considered as an important risk factor for development of chronic autoimmune thyroiditis, but data of various small studies are controversial. Despite the fact that Georgia is a sunny country, vitamin D deficiency is a widespread problem here. Thyroid diseases, including the chronic autoimmune thyroiditis, are also very common in Georgia. The aim of our research was to compare the level of vitamin D between the patients with chronic autoimmune thyroiditis and the healthy subjects. Methods. This retrospective study enrolled subjects, who were 18–70 years old and visited the clinics “Cortex” and “National Institute of Endocrinology” in 2018 or in 2019 from mid-spring to mid-summer. Data of thyroid-stimulating hormone, free thyroxine, antithyroid peroxidase antibodies, antithyroglobulin antibodies, thyroid ultrasonography, and 25(OH) vitamin D were retrospectively analysed based on medical history. In total, data of 1295 patients were collected. The statistical processing of data was performed through the SPSS 20 program. Results. The negative association between thyroid-stimulating hormone, antithyroid peroxidase antibodies, antithyroglobulin antibodies, heterogeneous parenchyma of thyroid gland, and vitamin D was found in women. Statistically significant association was not detected in men. Conclusions. Serum vitamin D is lower in women with autoimmune thyroiditis and primary hypothyroidism. Further studies are needed to evaluate the influence of vitamin D supplementation on thyroid autoantibody positivity or primary hypothyroidism.

scholarly journals Vitamin D and thyroid autoimmunity

2015 ◽  
Vol 21 (3) ◽  
pp. 157-162
Author(s):  
Eugenia Petrova ◽  
C. Dumitrache ◽  
Andra Buruiana ◽  
Maria Olaru ◽  
Irina Popescu ◽  
...  
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Autoimmune Thyroiditis ◽  
Thyroid Autoimmunity ◽  
Vitamin D Status ◽  
Chronic Thyroiditis ◽  
Autoimmune Thyroid ◽  
Chronic Autoimmune Thyroiditis ◽  
Vitamin D Levels ◽  
A Prospective Study

ABSTRACT Vitamin D deficiency is a global health problem, its role as an immune modulator being recently emphasized. Recent studies are increasingly suggesting that vitamin D plays a significant role in reducing the incidence and progression of autoimmune diseases. Furthermore, it was reported that patients with Hashimoto’s thyroiditis, an autoimmune thyroid disease had lower vitamin D levels [1]. We initiated a prospective study, for a period of 6 months with a study group represented by 160 patients admitted to the National Institute of Endocrinology “CI Parhon” in the period 2013 -2014. Patients were divided into 3 groups: 121 patients without thyroid pathology, 22 patients diagnosed with chronic autoimmune thyroiditis, who received 2000 IU cholecalciferol daily, 17 patients diagnosed with chronic autoimmune thyroiditis, which did not receive cholecalciferol. We found that patients with chronic thyroiditis have a poor vitamin D status with ATPO values negatively correlating with 25 (OH) vitamin D levels. Treatment with cholecalciferol not only improves vitamin D status but also lowers antithyroid antibodies titres. Keywords: vitamin D deficiency, chronic

Prevalence and determinants of vitamin D deficiency in pregnant women and their neonates: a multicentric study in Switzerland

2017 ◽  
Author(s):  
JP Krieger ◽  
S Cabaset ◽  
A Richard ◽  
L Ganeo-Christoffel ◽  
C Canonica ◽  
...  
Keyword(s):  
Vitamin D ◽  
Pregnant Women ◽  
Vitamin D Deficiency ◽  
Multicentric Study

Determination of Pregnant women Knowledge toward Risk Factors of Vitamin D Deficiency and Measuring Level During Pregnancy in Al- Nasiriyah City

2020 ◽  
Vol 23 (13) ◽  
Author(s):  
Ali Abdulhakeem Hassan Albakaa ◽  
Amer Muhssen Naser ◽  
Ali Riyad Saleim
Keyword(s):  
Risk Factors ◽  
Vitamin D ◽  
Pregnant Women ◽  
Vitamin D Deficiency

scholarly journals Pooled estimate of vitamin D deficiency among pregnant women in India: a systematic review and meta-analysis

2021 ◽  
Vol 40 (1) ◽  
Author(s):  
Angeline Jeyakumar ◽  
Vidhya Shinde ◽  
Reshma Ravindran
Keyword(s):  
Systematic Review ◽  
Vitamin D ◽  
Pregnant Women ◽  
Vitamin D Deficiency ◽  
Meta Analysis ◽  
Health Concern ◽  
Study Quality ◽  
Care Services ◽  
Pooled Prevalence ◽  
Women In India

Abstract Background Vitamin D deficiency among pregnant women is a public health concern globally. In India, individual studies report high prevalence. However, lack of national data masks the true burden. This work determined the pooled prevalence of vitamin D deficiency among pregnant women in India through a systematic review of literature and meta-analysis. Methods Three different search engines yielded 15 eligible articles. Study quality was assessed by 10 different criteria and summary of study quality was categorized as per Cochrane standards. Meta-analysis was performed to estimate pooled prevalence of vitamin D deficiency among healthy pregnant women and heterogeneity among selected studies. A sample of n = 4088 was used to study the pooled prevalence among pregnant women. Results The random effects combined estimate was 32.35% (95% CI, (12.58–117.48). High heterogeneity (tau2 = 0.39, I2 = 100%) and high risk of bias was observed among the selected studies. The test for overall effect was observed to be z = 2.54(P = 0.01). Conclusion Pooled estimate > 30% emphasizes the need for screening through antenatal care services and initiate preventive measures to address the deficiency.

Severe vitamin D deficiency among pregnant women and their newborns in Turkey

2014 ◽  
Vol 28 (5) ◽  
pp. 548-551 ◽  
Author(s):  
Mesut Parlak ◽  
Salih Kalay ◽  
Zuhal Kalay ◽  
Ahmet Kirecci ◽  
Ozgur Guney ◽  
...  
Keyword(s):  
Vitamin D ◽  
Pregnant Women ◽  
Vitamin D Deficiency ◽  
Severe Vitamin

Most Pregnant Women and A Half of 1-year-old Children in Japan Have Vitamin D Deficiency: Results from An Inner-City Birth Cohort

2018 ◽  
Vol 141 (2) ◽  
pp. AB159
Author(s):  
Fumiya Yamaide ◽  
Madoka Tomura ◽  
Mamoru Sato ◽  
Yoichi Suzuki ◽  
Fumio Nomura ◽  
...  
Keyword(s):  
Vitamin D ◽  
Inner City ◽  
Pregnant Women ◽  
Vitamin D Deficiency ◽  
Birth Cohort

scholarly journals Vitamin D status in pregnant women and their newborns in a tertiary care hospital

2018 ◽  
Vol 7 (12) ◽  
pp. 5071
Author(s):  
Harleen Kour ◽  
Shashi Gupta ◽  
Swarn K. Gupta ◽  
Bawa Ram Bhagat ◽  
Gagan Singh
Keyword(s):  
Vitamin D ◽  
Pregnant Women ◽  
Vitamin D Deficiency ◽  
Tertiary Care ◽  
North India ◽  
Care Hospital ◽  
Vitamin D Status ◽  
Pregnant Females ◽  
Vitamin D Levels ◽  
Maternal And Newborn

Background: In the recent years there has been an increased understanding of the role that vitamin D plays in regulation of cell growth, calcium absorption and immunity and its impact on the developing fetus and maternal health is of significant concern. This study aims at evaluating the Vitamin D status in pregnant women and their newborns.Methods: A cross sectional study was done on 100 pregnant females according to inclusion and exclusion criteria. At the time of delivery, maternal blood was collected, and newborn samples were taken from newborn side of umbilical cord and sent for analysis.Results: The prevalence of Vitamin D deficiency has been found to be 85% of pregnant females and 91% of the newborns. Only 5% of pregnant females and 1% of the newborns showed Vitamin D sufficiency. Maternal and newborn vitamin D levels show a positive correlation. Mean maternal and newborn Vitamin D levels were found to be 16.78±7.04 ng/mL and 11.29±5.75 ng/ml.Conclusions: Vitamin D deficiency is highly prevalent among pregnant women in north India. Low maternal vitamin D levels lead to vitamin D deficiency in the newborns also.

scholarly journals Prevalence of vitamin D deficiency and insufficiency in pregnant women: a longitudinal study

2010 ◽  
Vol 69 (OCE1) ◽  
Author(s):  
V. A. Holmes ◽  
M. S. Barnes ◽  
H. D. Alexander ◽  
P. McFaul ◽  
J. M. W. Wallace
Keyword(s):  
Vitamin D ◽  
Longitudinal Study ◽  
Pregnant Women ◽  
Vitamin D Deficiency
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