Safety and success rate of vaginal birth after two cesarean sections: retrospective cohort study

Objective. To determine the effectiveness of trial of labor after cesarean section (TOLAC) and the factors associated with a successful TOLAC. Materials and Methods. A retrospective cohort study was conducted on consecutive singleton pregnancies with a previous single low-transverse cesarean section planned for TOLAC at a tertiary teaching hospital. The potential risk factors of a successful TOLAC were compared with those associated with a failed TOLAC. A simple audit system used in the first two years was also taken into account in the analysis as a potential factor for success. Results. During the study period, 2,493 women were eligible for TOLAC and 704 of them were scheduled for TOLAC, but finally 592 underwent TOLAC. Among them, 355 (60%) had a successful vaginal birth and 237 (40%) had a failed TOLAC. The independent factors associated with the success rate included the audit system, prior vaginal birth, low maternal BMI, and lower birth weight or gestational age, whereas induction of labor and recurring indications in previous pregnancy significantly increased the risk of having a failed TOLAC. Strikingly, the strongest predictor of a successful TOLAC was the audit system with OR of 6.4 (95%CI: 3.9-10.44), followed by a history of vaginal birth in previous pregnancies (OR: 3.2; 95%CI: 1.87-5.36). Conclusion. The simple audit system had the greatest impact on the success rate of TOLAC, instead of the less powerful obstetrical factors as reported in previous reports. The audit system is the only potential factor that could be strengthened to improve the success rate.

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Factors Predisposing to Perinatal Death Related to Uterine Rupture During Attempted Vaginal Birth After Caesarean Section: Retrospective Cohort Study

Yearbook of Pediatrics ◽

10.1016/s0084-3954(07)70228-2 ◽

2006 ◽

Vol 2006 ◽

pp. 383-384

Author(s):

J.A. Stockman

Keyword(s):

Cohort Study ◽

Caesarean Section ◽

Retrospective Cohort Study ◽

Uterine Rupture ◽

Retrospective Cohort ◽

Perinatal Death ◽

Vaginal Birth ◽

Vaginal Birth After Caesarean

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Status and Determinants of Treatment Outcomes Among New Tuberculosis Patients in South Korea: A Retrospective Cohort Study

Asia Pacific Journal of Public Health ◽

10.1177/10105395211000529 ◽

2021 ◽

pp. 101053952110005

Author(s):

Hyunjin Son ◽

Jeongha Mok ◽

Miyoung Lee ◽

Wonseo Park ◽

Seungjin Kim ◽

...

Keyword(s):

Cohort Study ◽

South Korea ◽

Success Rate ◽

Treatment Outcomes ◽

Retrospective Cohort Study ◽

Retrospective Cohort ◽

Health Care Facilities ◽

Tuberculosis Patients ◽

Lost To Follow Up

This is a retrospective cohort study using notification data in South Korea. We evaluated the nationwide status, regional differences, and the determinants of treatment outcomes among tuberculosis patients. Treatment success rate improved from 77.0% in 2012 to 86.0% in 2015. The lost to follow-up rate was higher among older people, males, and foreign nationals. Health care facilities designated for the Public-Private Mix (PPM) project showed higher success rate and lower rate of lost to follow-up. Moreover, municipalities with low regional deprivation index had higher PPM project coverage. Since there is a large regional difference in the coverage of the PPM project, an additional community-based support program should be implemented, especially for tuberculosis patients residing in region with low PPM project coverage.

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Effect of chest tube position on the success rate of pleurodesis: A retrospective cohort study

Egyptian Journal of Chest Diseases and Tuberculosis ◽

10.1016/j.ejcdt.2017.08.005 ◽

2017 ◽

Vol 66 (4) ◽

pp. 635-638

Author(s):

Tomoyasu Takemura ◽

Shunkichi Ikegaki ◽

Emiko Saito ◽

Hirotaka Matsumoto ◽

Mariko Shinomiya ◽

...

Keyword(s):

Cohort Study ◽

Success Rate ◽

Retrospective Cohort Study ◽

Chest Tube ◽

Retrospective Cohort ◽

Tube Position

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Risk factors for obstetric anal sphincter injuries at vaginal birth after caesarean: a retrospective cohort study

International Urogynecology Journal ◽

10.1007/s00192-019-03978-x ◽

2019 ◽

Vol 30 (10) ◽

pp. 1747-1753 ◽

Cited By ~ 4

Author(s):

Joanna C. D’Souza ◽

Ash Monga ◽

Douglas G. Tincello

Keyword(s):

Risk Factors ◽

Cohort Study ◽

Anal Sphincter ◽

Retrospective Cohort Study ◽

Retrospective Cohort ◽

Vaginal Birth ◽

Obstetric Anal Sphincter Injuries ◽

Vaginal Birth After Caesarean

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Factors predisposing to perinatal death related to uterine rupture during attempted vaginal birth after caesarean section: retrospective cohort study

BMJ ◽

10.1136/bmj.38160.634352.55 ◽

2004 ◽

Vol 329 (7462) ◽

pp. 375 ◽

Cited By ~ 92

Author(s):

Gordon C S Smith ◽

Jill P Pell ◽

Dharmintra Pasupathy ◽

Richard Dobbie

Keyword(s):

Cohort Study ◽

Caesarean Section ◽

Retrospective Cohort Study ◽

Uterine Rupture ◽

Retrospective Cohort ◽

Perinatal Death ◽

Vaginal Birth ◽

Vaginal Birth After Caesarean

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1342. Impact of HIV Infection on Treatment Outcome of New Tuberculosis Patients Attending Tuberculosis and Antiretroviral Treatment Services in the Community-Based Hospital, Thailand: A Retrospective Cohort Study

Open Forum Infectious Diseases ◽

10.1093/ofid/ofz360.1206 ◽

2019 ◽

Vol 6 (Supplement_2) ◽

pp. S485-S486

Author(s):

Subencha Pinsai

Keyword(s):

Cohort Study ◽

Treatment Outcome ◽

Hiv Infection ◽

Success Rate ◽

Retrospective Cohort Study ◽

Retrospective Cohort ◽

Treatment Success ◽

Treatment Success Rate ◽

Factors Associated ◽

The Impact

Abstract Background Tuberculosis (TB) and HIV are one of the significant public health problems in Thailand, and an estimated 15,000 individuals have a dual infection. Both HIV and TB each disease speeds up the progression of each other. TB is the leading cause of death in HIV-infected individuals, and HIV coinfected TB patients have disease-specific, and treatment affected their treatment outcomes. There is insufficient evidence on issues of TB and HIV co-infection patients received treatment. This study aimed to assess the impact of HIV status on treatment outcome of TB patients. Methods We conducted a retrospective cohort study among TB patients who registered to service at Chaophraya Abhaibhubejhr Hospital, Prachin Buri, Thailand from October 1, 2017 to October 31, 2018. All patients’ demographic data, diagnosis, and treatment were retrieved. Clinical characteristics, treatment outcome, and factors associated with treatment outcome were analyzed. Results There were 49 (10.65%) HIV among 460 TB patients with a median (IQR) age of 44 (32–61) years old and 65.2% were males. Disseminated TB and extrapulmonary TB were higher in HIV coinfected group (P < 0.001). All pulmonary TB patients’ lower lobe involvement was higher in HIV coinfected group (62.50 vs. 36.00, P = 0.001). In HIV coinfected group median CD4 was 134 cell/mm3 (IQR 19–294), 66.67% were diagnosed HIV infection after TB diagnosis, the median time from TB diagnosed to antiretroviral was 29 days (IQR 21–48). The overall treatment success rate was 93.04%; the treatment success rate was similar in HIV coinfected TB patients (89.80%) and non- HIV-infected patients (93.43%) (P = 0.66).Adverse drug reactions were higher in HIV coinfected group (44.89% vs 12.41%) (P < 0.001). By multiple stepwise logistic regression, factors associated with anti-TB drug adverse reactions were having HIV infection (OR 7.99; 95% CI 3.73–17.10, P < 0.001), Age >60 years (OR 2.64; 95% CI 1.43–4.87, P = 0.002) and female sex (OR 1.97; 95% CI 1.11–3.52, P = 0.02). Conclusion There is a high TB treatment success rate among patients who have treated for TB, but adverse drug events in HIV co-infected TB patients is higher than that observed in non-HIV-infected patients. Disclosures All authors: No reported disclosures.

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