Synchronous appearance of extensive pleomorphic adenoma with Warthin’s tumour within the superficial lobe of the parotid

2017 ◽  
Vol 6 (1) ◽  
pp. 35-38 ◽  
Author(s):  
Edward Mollin ◽  
Dominik Stodulski ◽  
Czesław Stankiewicz
Keyword(s):  
Parotid Gland ◽  
Pleomorphic Adenoma ◽  
Surgical Approach ◽  
Course Of Disease ◽  
Superficial Lobe ◽  
Warthin’S Tumour

The paper describes 65-year-old man diagnosed with a widespread pleomorphic adenoma of accesory gland coexisting with Wartin’s tumor of the parotid gland superficial lobe. The course of disease and its treatment considering the surgical approach are presented.

Pleomorphic Adenoma: A Preliminary Histopathologic Comparison between Tumors Occurring in the Deep and Superficial Lobes of the Parotid Gland

1992 ◽  
Vol 71 (6) ◽  
pp. 254-257 ◽  
Author(s):  
D. M. Fliss ◽  
R. Rival ◽  
P. Gullane ◽  
D. Mock ◽  
J. L. Freeman
Keyword(s):  
Parotid Gland ◽  
Mitotic Activity ◽  
Pleomorphic Adenoma ◽  
Cell Population ◽  
Surgical Approach ◽  
Deep Lobe ◽  
Histopathological Features ◽  
Superficial Lobe ◽  
Aggressive Surgical Approach ◽  
Tumoral Cell

Twenty-four cases of pleomorphic adenoma of the parotid gland were retrospectively reviewed. The histopathological features of capsular thickness, penetration and completeness, tumoral cell population and mitotic activity were analyzed in twelve superficial lobe and twelve deep lobe tumors. The capsules were found to be significantly thicker and less likely to be penetrated by tumor in the deep lobe group. No significant differences in completeness of encapsulation, cell population or mitotic activity were found between the two groups. This may explain the clinical suggestion that the less aggressive surgical approach which is often performed does not compromise the prognosis for recurrence in the deep lobe lesions.

Co-existing pleomorphic and tubular basal cell adenomas of the parotid gland

1997 ◽  
Vol 111 (2) ◽  
pp. 182-185 ◽  
Author(s):  
Louis T. C. Chow ◽  
W. H. Chow
Keyword(s):  
Parotid Gland ◽  
Pleomorphic Adenoma ◽  
Basal Cell ◽  
Double Layers ◽  
Basal Cell Adenoma ◽  
Cystic Change ◽  
Cell Adenoma ◽  
Superficial Lobe ◽  
Warthin’S Tumour ◽  
Left Parotid Gland

AbstractWe report a hitherto undescribed case of co-existence of a pleomorphic adenoma and a tubular basal cell adenoma affecting the superficial lobe of the left parotid gland of a 53-year-old man. The histology of the pleomorphic adenoma is also of interest in that the prominent adipose metaplasia of its myxoid stroma yielded an appearance reminiscent of myxoid lipoma. The tubular basal cell adenoma showed gross cystic change, and its solid portion consisted of closely packed tubules lined by double layers of cuboidal cells with little intervening stroma. Unlike Warthin's tumour and membranous basal cell adenoma, both pleomorphic and tubular basal cell adenomas exhibit no propensity towards multicentricity or bilaterality. We, therefore, believe that their co-existence in the superficial lobe of the parotid gland of our patient is a mere concidence rather than association.

scholarly journals A Rare Case of Paediatric Pleomorphic Adenoma of the Parotid Gland

2021 ◽  
Vol 8 (2) ◽  
Author(s):  
Tantry D ◽  
◽  
Chitra G ◽  
Keyword(s):  
Parotid Gland ◽  
Pleomorphic Adenoma ◽  
Surgical Excision ◽  
Interesting Case ◽  
Tumour Mass ◽  
Salivary Gland Tumours ◽  
Superficial Lobe ◽  
The Face ◽  
Utmost Care ◽  
The Right

Pleomorphic adenomas are benign salivary gland tumours, which predominantly affect the superficial lobe of the parotid gland. The “pleomorphic” nature of the tumour can be explained on the basis of its epithelial and connective tissue origin. The tumour has a female predilection between 30-50 years of age. Slowly progressing asymptomatic swelling is the usual presentation of the tumour. Surgical excision of the tumour mass forms the mainstay of treatment, with utmost care taken to preserve the facial nerve. This case report aims to throw light on an interesting case of pleomorphic adenoma of the parotid gland in a 10 years old female patient. The patient presented with a slowly progressing asymptomatic swelling on the right side of the face, which was diagnosed to be pleomorphic adenoma of right parotid gland. The aim of the study is to discuss how to proceed regarding the further management.

scholarly journals Etiology and familial inheritance of pleomorphic adenomas

2017 ◽  
Vol 5 (1) ◽  
Author(s):  
Krysten Clark
Keyword(s):  
Salivary Gland ◽  
Parotid Gland ◽  
Pleomorphic Adenoma ◽  
White Male ◽  
Salivary Gland Tumor ◽  
Major Salivary Gland ◽  
Gland Tumor ◽  
Superficial Lobe ◽  
Increased Risk ◽  
Pleomorphic Adenomas

Background: A pleomorphic adenoma is the most common salivary gland neoplasm in both children and adults. Pleomorphic adenomas are derived from ductal and myoepithelial cells and are most commonly found in the superficial lobe of the parotid gland. The purpose of this article is to discuss the genes involved in pleomorphic adenomas and the possible autosomal dominant mode of inheritance. Case Description: The first patient was a white male who was diagnosed with carcinoma ex pleomorphic adenoma, a highly aggressive tumor, at the age of 57. He had an undiagnosed pleomorphic adenoma for approximately 15 years prior. The tumor was excised and the patient underwent radiation in the location of his parotid gland for 4 years until he deceased. The second patient is a white female, his daughter, who was diagnosed with a benign pleomorphic adenoma at the age of 46. Her salivary gland tumor was excised and normal follow up appointments occurred. Practical Implications: Pleomorphic adenomas most commonly affect the parotid gland, the largest of the three major salivary gland tumors. Occurrence and excision of this salivary gland tumor will cause a decrease in the secretion of saliva, leading to a dry mouth and an increased risk of caries.

scholarly journals A Case of Pleomorphic Adenoma of the Deep Lobe Mis-conceived as Tumor of Superficial Lobe of the Parotid Gland

1994 ◽  
Vol 5 (1) ◽  
pp. 114-117
Author(s):  
Sung Wan Kim ◽  
Jong Hoon Won ◽  
Yul Gwan Lee ◽  
Kwang Il Kim
Keyword(s):  
Parotid Gland ◽  
Pleomorphic Adenoma ◽  
Deep Lobe ◽  
Superficial Lobe

scholarly journals Recurrent Multinodular Pleomorphic Adenoma of Parotid Gland- A Case Report

2021 ◽  
Author(s):  
Priya Kanagamuthu ◽  
Swetha Thirumurthi ◽  
S Rajasekaran ◽  
S Prabakaran ◽  
RB Namasivaya Navin
Keyword(s):  
Parotid Gland ◽  
Facial Nerve ◽  
Pleomorphic Adenoma ◽  
Previous History ◽  
Significant Risk ◽  
Superficial Parotidectomy ◽  
Parotid Region ◽  
Superficial Lobe ◽  
History Of ◽  
The Right

Pleomorphic adenoma or benign salivary gland tumours predominantly affects the superficial lobe of parotid gland. It is a slow growing swelling with or without facial nerve involvement with female predilection in third and fifth decade of life. The origin of the tumour is both epithelial and connective tissue and hence it is of pleomorphic nature. After surgery, its recurrence rate varies considerably and seems to depend more on the surgical technique used. A 49-year-old male patient, presented with complaints of swelling in front of right ear and right parotid region for past eight years. He gave previous history of similar swelling in the right parotid region and history of previous surgery done elsewhere in 2009. Right superficial parotidectomy was done following which he was asymptomatic for two years. On examination of right parotid- a multilobulated irregular swelling was present in right parotid region and the swelling extended till the right ear lobule. The swelling hid previous surgical scar. Facial nerve was clinically intact. Fine Needle Aspiration Cytology (FNAC) was suggestive of Pleomorphic Adenoma. Magnetic Resonance Imaging (MRI) with contrast revealed that the lesions were arising from superficial lobe of the parotid gland. Right superficial parotidectomy was planned. Mass was excised and sent for histopathological examination and was reported to be Pleomorphic Adenoma. Patient is still on follow-up and no recurrence has been noted. The rate of recurrence depends on tumour spillage, intra-surgical rupture, or any histopathological feature. There is significant risk for local recurrence if the microscopic finger like formation (pseudopodia) of tumour tissue extends beyond the main mass.

scholarly journals Pleomorphic Adenoma of Three Different Sites: a Consecutive Case Series

2021 ◽  
Vol 28 (2) ◽  
pp. 253-256
Author(s):  
Felice FAIZAL ◽  
◽  
Ankur AHUJA ◽  
R. CHATTERJEE ◽  
◽  
...  
Keyword(s):  
Salivary Gland ◽  
Parotid Gland ◽  
Pleomorphic Adenoma ◽  
Salivary Gland Tumor ◽  
Case Series ◽  
Neck Region ◽  
Surgical Excision ◽  
Histopathological Analysis ◽  
Superficial Lobe ◽  
Utmost Care

Background: Pleomorphic adenomas are benign salivary gland tumors predominantly arising from the superficial lobe of the parotid gland and rarely from the small salivary glands located at various locations including parotid, lacrimal duct, lip, floor of the mouth etc. Surgical excision of the tumor mass is the treatment of choice with utmost care taken to preserve the facial nerve in cases involving the parotid gland. Case details: This case series highlights three consecutive cases of pleomorphic adenoma arising from three different locations. Conclusion: Pleomorphic adenoma is the commonest salivary gland tumor characterized by diverse histomorphological features and can occur at any site where salivary tissue is present. Careful histopathological analysis should be done in all tumors arising especially in the head and neck region.

scholarly journals Co-expression of Myoepithelial and Melanocytic Features in Carcinoma Ex Pleomorphic Adenoma

2021 ◽  
Author(s):  
Costantino Ricci ◽  
Federico Chiarucci ◽  
Francesca Ambrosi ◽  
Tiziana Balbi ◽  
Barbara Corti ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Salivary Gland ◽  
Parotid Gland ◽  
Pleomorphic Adenoma ◽  
Salivary Gland Tumors ◽  
Melanin Pigment ◽  
Carcinoma Ex Pleomorphic Adenoma ◽  
Pertinent Literature

AbstractThe presence of melanin pigment and melanocytic markers expression have been rarely reported in salivary gland tumors. Herein, two cases of carcinoma arising in pleomorphic adenoma of the parotid gland and showing diffuse expression of myoepithelial and melanocytic markers are described. The clinical-pathological clues useful in the differential diagnosis with melanoma are discussed. In addition, a review of the pertinent literature is also proposed, discussing the pathologic mechanisms potentially involved in this phenomenon.

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