Retrospective evaluation of risk factors for oral cavity and oropharynx cancers in patients under the program of head and neck cancers prevention

Introduction: The aim of the study was to analyze the risk factors for oral cavity and pharyngeal cancer in people examined under the Head and Neck Cancer Prophylaxis Program. Material and methods: The study was conducted in a total of 300 patients, including 186 women and 114 men, as part of the Head and Neck Cancer Prevention Program in 2014–2018. Before the laryngological examination, the patients completed a demographic and medical questionnaire regarding the risk factors of head and neck cancer, including education, reported disease symptoms, smoking addiction, number of cigarettes smoked daily, alcohol consumption, frequency of visits in a dental office, oral hygiene measures, number of sexual partners, oral sex, family medical history of head and neck cancer. Results: The subjects reported the following symptoms: hoarseness 43.33%, difficulty swallowing 21.33%, pain or mouth burning 20.33% and other symptoms were observed in 46.33%. The main dental symptoms were: bleeding from the gums during teeth brushing in 48.89%, dry mouth 45.56%. Currently 20.33% of respondents smoke, whereas 54% of patients smoked in the past. In the analyzed material, the majority (80%) consumed alcoholic beverages. 27.67% of respondents admitted having oral sex, including 24.73% of women and 32.46% of men. After performing the extended diagnostics, the tumor was found in 10% of the subjects. C onclusions: Statistical significance of differences was found: between hoarseness and alcohol consumption, both in women and in men, between hoarseness and smoking in women, between difficulty in swallowing and smoking in women, between burning/pain in the mouth and smoking in men, between hoarseness and the cultivation of oral sex in men, between the difficulty of swallowing and the practice of oral sex in the studied men and between burning/pain in the oral cavity and the occurrence of malignancy.

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Analysis of risk factors for oral cavity and oropharynx cancer in the authors’ own material

Otolaryngologia Polska ◽

10.5604/01.3001.0009.8411 ◽

2017 ◽

Vol 71 (2) ◽

pp. 23-28 ◽

Cited By ~ 1

Author(s):

Joanna Nowosielska-Grygiel ◽

Kalina Owczarek ◽

Marzena Bielińska ◽

Magdalena Wacławek ◽

Jurek Olszewski

Keyword(s):

Risk Factors ◽

Head And Neck Cancer ◽

Oral Cavity ◽

Head And Neck ◽

Neck Cancer ◽

Sexual Partners ◽

Oral Sex ◽

Cancer Awareness ◽

Oropharynx Cancer ◽

Hoarse Voice

Introduction: The aim of the study was to analyse the risk factors for oral cavity and oropharynx cancer in peopled examined under the Head and Neck Cancer Awareness Week in 2016, Lodz. Material and methods. In Lodz, 21st September 2016, under the Head and Neck Cancer Awareness Week, 106 people, including 67 women aged 29–77 and 39 men aged 23–84, underwent preventive examinations in the hospital department. Prior to the laryngological examination, the patients were asked to answer questions that referred to their education, medical case history, symptoms, smoking habits with the number of cigarettes per day, alcohol intake, the number of lifetime sexual partners, oral sex engagement, incidents of head and neck cancer in the family history. Results: The major part of the examined patients were women and men with the secondary and high level of education, 47,76% and 35,82%, and 58,97% and 35,91% respectively. The patients were informed by mass media about the planned preventive medical examinations – 80,60% women and 79,49% men. The most common symptoms reported by women were: hoarse voice in 61,19% cases, dysphagia in 32,84% cases and burning sensation and/or pain in the oral cavity in 29,85% cases. The examined male patients mainly showed hoarse voice (46,15%), other symptoms (43,59%) and dysphagia (25,64%). 28,35% women and 28,20% men smoked cigarettes, while passive smokers were 22,38% and 25,64% respectively. Alcohol consumption was reported by 67,16% women and 82,05% men, rather occasionally. Having oral sex was noted in 25,37% women and 38,46% men, mostly with multiple sexual partners. Among the studied patients, 13,43% women and 5,12% men suffered from malignant cancer, including 2,98% women and 2,56% men who reported head and neck carcinoma in the medical interview. On the basis of the interview and ENT examination, 11,94% women and 17,94% men were qualified for the extended oncological diagnostics. Conclussion. The Fourth Head and Neck Cancer Awareness Week shows the increased interest in preventive screening, especially oncological screening, and thus the necessity of such preventive activities in the future.

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Profile of Head and Neck Cancer Patients at Hasan Sadikin Hospital in 2013-2018

Oto Rhino Laryngologica Indonesiana ◽

10.32637/orli.v50i2.361 ◽

2021 ◽

Vol 50 (2) ◽

pp. 141

Author(s):

Nur Nathania ◽

Yussy Afriani Dewi ◽

Agung Dinasti Permana

Keyword(s):

Risk Factors ◽

Head And Neck Cancer ◽

Nasopharyngeal Carcinoma ◽

Alcohol Consumption ◽

Head And Neck ◽

General Hospital ◽

Neck Cancer ◽

Undifferentiated Carcinoma ◽

Salted Fish ◽

Stadium Iv

ABSTRACTBackground: Head and neck cancer (HNC) is the 6th highest cancer worldwide. Risk factors include history of smoking, exposure of carcinogen, diet, oral hygiene, HPV and EBV infections, genetic, and alcohol consumption. Purpose: To identify the profile of HNC patients in the Department of Otorhinolaryngology-Head and Neck Surgery (ORL-HNS) Hasan Sadikin General Hospital Bandung from 2013 to 2018. Method: A retrospective descriptive study was conducted in 2013-2018 in the Department of ORL-HNS Hasan Sadikin General Hospital, using total sampling method. Medical record of the patients were used as secondary data. Result: There were 2952 HNC patients consisted of 1689 males and 1263 females. Most of the subjects were graduated from elementary school (45.56%), with mean age 47.45 years old. The majority types of HNC were nasopharyngeal (31.20%), sinonasal (19.65%) and laryngeal (14.16%) carcinoma. The main histopathological types were undifferentiated carcinoma (47.15%) and squamous cell carcinoma (34.08%). The major risk factors were smoking and salted fish consumptions. Discussion: Unlike previous studies, our study found out that most HNC cases occurred in patients under the age of 30 years old. In this research, smoking was the highest risk factor of research subjects, followed by salted fish intake, mosquito burnt coils, and alcohol consumption. Nasopharyngeal carcinoma and stadium IV were the highest incidence of HNC, mostly found in male patients. Histopathologically, the dominant type was the undifferentiated carcinoma. Conclusion: Nasopharyngeal carcinoma was the main cancer type. The main histopathological type was undifferentiated carcinoma. The main risk factors were smoking and salted fish consumptions. ABSTRAKLatar belakang: Karsinoma kepala leher (KKL) merupakan keganasan terbanyak ke enam di dunia. Faktor risiko KKL antara lain riwayat merokok, paparan karsinogen, diet, kebersihan mulut, infeksi Human Papilloma Virus, Virus Epstein Barr, genetika, konsumsi alkohol. Tujuan: Untuk mengetahui profil penderita KKL di Departemen T.H.T-K.L Rumah Sakit Hasan Sadikin Bandung, tahun 2013- 2018. Metode: Penelitian deskriptif retrospektif dengan total sampling, pada periode 2013-2018 di Dept/KSM THT-KL RSUP Dr Hasan Sadikin. Rekam medis subjek penelitian digunakan sebagai data sekunder. Hasil: Terdapat 2.952 penderita KKL terdiri dari 1.689 laki-laki dan 1.263 perempuan. Mayoritas berpendidikan SD (45,56%), dengan rerata usia 47,45 tahun. Jenis KKL terbanyak karsinoma nasofaring (31,20%), sinonasal (19,65%), dan laring (14,16%). Karakteristik histopatologi terbanyak karsinoma tak berdiferensiasi (47,15%) dan karsinoma sel skuamosa (34,08%). Faktor risiko terbanyak merokok serta konsumsi ikan asin. Diskusi: Berbeda dengan penelitian sebelumnya, penelitian kami mendapatkan kasus KKL terbanyak didapati pada pasien di bawah usia 30 tahun. Didapatkan juga faktor risiko tertinggi adalah merokok, diikuti oleh mengonsumsi ikan asin, obat nyamuk bakar, dan minum alkohol. Angka kejadian KKL terbanyak adalah karsinoma nasofaring stadium IV, yang kebanyakan didapati pada pasien laki-laki. Secara histopatologi, tipe yang dominan adalah jenis karsinoma tak berdiferensiasi. Kesimpulan: Karsinoma nasofaring merupakan jenis KKL terbanyak. Jenis histopatologi terbanyak karsinoma tak berdiferensiasi. Faktor risiko KKL yang paling banyak ditemui yaitu merokok dan konsumsi ikan asin.

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Alcohol Drinking Pattern and Risk of Head and Neck Cancer: A Nationwide Cohort Study

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph182111204 ◽

2021 ◽

Vol 18 (21) ◽

pp. 11204

Author(s):

Hye Yeon Koo ◽

Kyungdo Han ◽

Dong Wook Shin ◽

Jung Eun Yoo ◽

Mi Hee Cho ◽

...

Keyword(s):

Risk Factor ◽

Cohort Study ◽

Head And Neck Cancer ◽

Alcohol Consumption ◽

Oral Cavity ◽

Head And Neck ◽

Neck Cancer ◽

Daily Amount ◽

Average Alcohol ◽

Drinking Frequency

Alcohol consumption is a major risk factor for head and neck cancer (HNC), yet little data exist examining drinking patterns and HNC risk. In this population-based, retrospective cohort study, 11,737,467 subjects were recruited from the Korean National Health Insurance Service database. The risks of overall HNC and HNC subtypes according to average alcohol consumption, drinking frequency, and daily amount were examined using Cox proportional hazard models. Over the median follow-up of 6.4 years, 15,832 HNC cases were identified. HNC risk linearly increased with drinking frequency (p-trend < 0.01; adjusted hazard ratio [aHR] 1.55, 95% confidence interval [CI] 1.45–1.67 in subjects who drank 7 days/week). HNC risk also increased according to daily amount of alcohol consumption (p-trend < 0.01), but plateaued from 5–7 units/occasion (aHR 1.25, 95% CI 1.19–1.31) to >14 units/occasion (aHR 1.26, 95% CI 1.13–1.40). When stratified by average alcohol consumption, drinking frequency, but not daily amount, showed a linear relationship with HNC risk in moderate and heavy drinkers. When comparing the HNC subtypes, similar tendencies were observed in cancers of the oral cavity, pharynx, and larynx, but not in the salivary gland. In conclusion, drinking frequency is a stronger risk factor for HNC, especially for cancer of the oral cavity, pharynx, and larynx, than the daily amount of alcohol consumption.

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